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Dai J.,State Key Laboratory for Modification of Chemical Fibers and Polymer MaterialsDonghua UniversityShanghai201620China | Bai J.,State Key Laboratory for Modification of Chemical Fibers and Polymer MaterialsDonghua UniversityShanghai201620China | Jin J.,State Key Laboratory for Modification of Chemical Fibers and Polymer MaterialsDonghua UniversityShanghai201620China | Yang S.,State Key Laboratory for Modification of Chemical Fibers and Polymer MaterialsDonghua UniversityShanghai201620China | Li G.,State Key Laboratory for Modification of Chemical Fibers and Polymer MaterialsDonghua UniversityShanghai201620China
Advanced Engineering Materials | Year: 2015

Biodegradable materials used for bone repair have recently gained greater attention. The improvement of the mineralization rate and the biocompatibility of are critical. In this study, natural pearl powder is added to polylactic acid (PLA) to accelerate both two properties of PLA. The results show that the amount of hydroxyapatite (HA) deposition on PLA/pearl composite increased with pearl content increasing up to 15wt%, especially at the beginning of mineralization. The HA is a poorly crystallized calcium-deficient type as indicated by FTIR, EDS, and XRD. Osteoblasts are used to evaluate cellular proliferation. An MTT assay reveals that composites are non-toxic and show better proliferation than pristine PLA. It is concluded that PLA/pearl could be more appropriate for bone repairs than PLA. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Source

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