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Radiastuti N.,State Islamic University of Jakarta | Mutea D.,State Islamic University of Jakarta | Sumarlin L.O.,State Islamic University of Jakarta
AIP Conference Proceedings | Year: 2017

An endophytic fungus is microorganisms that live inside plant tissues without harming its host and is capable of producing the same secondary metabolites as its host plant. The endophytic fungus is very diverse and important group of microorganisms. The objectives of the study are to identify endophyte Colletotrichum spp. using ITS rDNA analyze, alkaloid cinchona and antibacterial characteristics. Phylogenetic analysis of ITS rDNA regions and morphology are used to identify the species. The Chloroform extracts of filtrate were analyzed using the High Pressure Liquid Chromatography (HPLC) to determine the production of quinine. There were 13 isolates of Colletotrichum spp as endophytes with associated with Cinchona calisaya Wedd. from fruit (6 isolates), leaf (5 isolates), twig (1 isolate) and root (1 isolate). This is the first report as endophytes are associated with C. calisaya. Based on ITS phylogenetic analysis are introduced of 7 strains Colletotrichum sp, 1 strain closely with C. aegnigma, 2 strains closely C. cordylinicola, 1 strains C arxii, 2 strains nested C. karstii. The Colletotrichum sp. M1 (leaf), M3 (bark), M8 (fruit) and C. karstii M5 (fruit) are potential alkaloid quinine. Five strains of Colletotrichum spp. have antibacterial activity are selected against Staphylococcus aureus and nine Colletotrichum spp. against Escherichia coli. The endophyte identification of Colletotrichum species needs another gene other than ITS rDNA. © 2017 Author(s).


Artanti N.,Indonesian Institute of Sciences | Firmansyah H.,State Islamic University of Jakarta | Darmawan A.,Indonesian Institute of Sciences
Journal of Applied Pharmaceutical Science | Year: 2012

Mistletoes or benalu in bahasa Indonesia is a semi-parasitic plant that also known as medicinal plant. It used in t raditional/alternative medicine such as for for cough, diabetes, hypertension, cancer, diuretic, smallpox, ulcer, skin infection and after child-birth treatment. There are many species of mistletoes in Indonesia. Dendrophthoe pentandra (L.) Miq. is one of the Indonesian mistletoes species that commonly found grew on many different species of host plant. In this paper we reported in vitro toxicity, antioxidant and antidiabetes activities of MeOH and water extracts of D. pentandra grew on four different host plants (Stelechocarpus burahol, Spondias dulcis, Annona squamosa and Camellia sinensis). Toxicity was measured using brine shrimp lethality test (BSLT). Antioxidant activity was measured using DPPH free radical scavenging assay. Antidiabete s activity was measured using a-glucosidase inhibitor assay. The results show that all mistletoe s extracts tested (MeOH and water extracts) were non-toxic and show significant antidiabetes activity, whereas for antioxidant activity, only MeOH extracts show significant activity. Therefore, it is suggest that D. pentandra extracts are potential source for natural antioxidant and antidiabetes compounds.


Shahab N.,State Islamic University of Jakarta | Shahab N.,Kyushu University | Kajioka S.,Kyushu University | Seki N.,Kyushu University | Naito S.,Kyushu University
Urology | Year: 2012

Objective: We investigated the role of muscarinic receptor subtypes in calcium sensitization and their contribution to rho-kinase (ROK) and protein kinase C (PKC) pathways in carbachol (CCh)-induced contraction of human detrusor smooth muscle (DSM). Materials and Methods: α-toxin-permeabilized human DSM strips were prepared and mounted horizontally to record isometric force. The roles of M 2 and M 3 muscarinic receptors in Ca 2+ sensitization were studied using selective antagonists of M 2 (AF-DX116) and M 3 (4-DAMP) receptor subtypes. The effects of a selective inhibitor of ROK, Y-27632, and a selective inhibitor of PKC, bisindolylmaleimide I (GF-109203X), were also studied on contraction induced by 10 μM CCh with 100 μM guanosine triphosphate at a fixed 1 μM [Ca 2+] i after preincubation with 1 μM AF-DX116 or 1 μM 4-DAMP. Results: Carbachol-induced Ca 2+ sensitization was predominantly inhibited by 4-DAMP compared with AF-DX116. Four-DAMP equivalently inhibited the relaxation effect of 5 μM GF-109203X as well as that of 5 μM Y-27632 on CCh-induced Ca 2+ sensitization. AF-DX116 reduced the relaxation effect of Y-27632 to a greater degree than GF-109203X. Conclusion: The results of the present study have demonstrated the predominant role of M 3 receptor subtype in Ca 2+ sensitization and the relative contribution to ROK and PKC pathways. Our study also shows that the ROK pathway is dominant compared with the PKC pathway after M 2 receptor activation, which in turn is inferior, but not negligible, in producing Ca 2+ sensitization. © 2012 Elsevier Inc.


Nurhayati,State Islamic University of Jakarta
Lecture Notes in Electrical Engineering | Year: 2015

A problem of unbalanced energy consumption exist and it primarily depend role and on location of a particular node in the network. The in order to make use of their potential, researchers must find solution to some difficulties that are slowing down the wide spread use these networks. The other case the problem faced by wireless sensor networks is the energy efficiency that are used during routing occurs, it affects the lifetime of sensor and residual energy of wireless network. Cluster-based routing protocols are not the same in wireless sensor network (UCR), nodes are grouped into clusters that are not the same size or Unequal Cluster Routing Protocol (UCR) has disadvantages in choosing the head of the cluster if the distance from the node away from the base station and the higher energy from other nodes cause trouble hot spots. In this research will offer a solution efficiency energy and balance energy consumption to prolong lifetime of sensor nodes based on Dynamic Unequal Clustering Routing Protocol namely by focusing the cluster will be done with consideration of dynamic routing on the cluster node are unequal cluster. The next step can do re-clustering node to change between nodes as cluster member or cluster head, so they can save energy on the condition of the hot spots on the node closest to the base station. The routing protocol algorithm called The Dynamic Unequal Cluster Routing Protocol Based on Efficiency Energy in Wireless Sensor Network (DUCRBEE). The research methodology used is primary and secondary data collection and simulation methods. And the results will be shown by the simulation comparing DUCR new algorithm that will extend the lifetime of sensor nodes when compared with BCDCP and UCR. © Springer Science+Business Media Singapore 2015.


Atilola O.,University of Ibadan | Singh Balhara Y.P.,All India Institute of Medical Sciences | Stevanovic D.,General Hospital Sombor | Avicenna M.,State Islamic University of Jakarta | Kandemir H.,Harran University
Journal of Developmental and Behavioral Pediatrics | Year: 2013

Objective: To evaluate the prevalence, pattern, and sociodemographic correlates of self-reported mental health problems among a pilot sample of adolescents from 5 developing countries and to speculate the methodology and design of a larger scale study. Methods: The sociodemographic questionnaire was developed based on extant literature on the sociodemographic correlates of mental health problems among adolescents. Additional information about the socioeconomic status of parents/caregivers of the participants was obtained using the Family Affluence Scale (FAS). Mental health problems were evaluated using the Strength and Difficulty Questionnaire (SDQ). Logistic regression analysis was done to determine independent sociodemographic correlates of mental health problems. Results: A total of 1894 adolescents sampled from 5 countries completed the study. The prevalence of self-reported mental health problems was 10.5% (range, 5.8-15) with conduct and emotional problems being the most prevalent. When the raw total-SDQ scores were adjusted for age, gender, and FAS scores, there was a statistically significant difference in the mean scores among the adolescents from different countries (F = 17.23, p < .001). After controlling for all potential sociodemographic confounders, living with single parents or other nonparent care givers, having a chronic disabling physical condition, lower maternal education, and coming from a family in the lower FAS-score category were all independently associated with higher odds of mental health problems. Conclusions: Study has added to the currently limited data on prevalence of mental health problems among adolescents in developing countries. It further established that socioeconomic and family factors still play a major role in the mental health of children irrespective of region of the world. Significant but surmountable methodological issues for a larger scale study were raised. Copyright © 2013 Lippincott Williams & Wilkins.


King M.,McGill University | Noor H.,State Islamic University of Jakarta | Taylor D.M.,McGill University
Studies in Conflict and Terrorism | Year: 2011

Families might be an important source of norms that legitimize terrorism, an assumption that has yet to be tested empirically. To investigate this, surveys were administered to 20 immediate relatives of 16 Jema'ah Islamiyah (JI) members in Indonesia. Family members were found to agree with their kin's involvement in the violent activities of JI, and perceived their community as being supportive. Agreement with their relative's involvement in JI was predicted by anti-Western sentiment, not support for violent jihad. Kinship to a suicide bomber predicted less support for their family member's involvement in JI. Implications for deradicalization strategies are discussed. © Taylor & Francis Group, LLC.


Agus Y.,St. Luke's College of Nursing | Agus Y.,State Islamic University of Jakarta | Horiuchi S.,St. Luke's College of Nursing
BMC Pregnancy and Childbirth | Year: 2012

Background: Every year, nearly half a million women and girls needlessly die as a result of complications during pregnancy, childbirth or the 6 weeks following delivery. Almost all (99%) of these deaths occur in developing countries. The study aim was to describe the factors related to low visits for antenatal care (ANC) services among pregnant women in Indonesia.Method: A total of 145 of 200 married women of reproductive age who were pregnant or had experienced birth responded to the questionnaire about their ANC visits. We developed a questionnaire containing 35 items and four sections. Section one and two included the women's socio demographics, section three about basic knowledge of pregnancy and section four contained two subsections about preferences about midwives and preferences about Traditional Birth Attendant (TBA) and the second subsections were traditional beliefs. Data were collected using a convenience sampling strategy during July and August 2010, from 10 villages in the Tanjung Emas. Multiple regression analysis was used for preference for types of providers.Results: Three-quarter of respondents (77.9%) received ANC more than four times. The other 22.1% received ANC less than four times. 59.4% received ANC visits during pregnancy, which was statistically significant compared to multiparous (p = 0.001). Women who were encouraged by their family to receive ANC had statistically significant higher traditional belief scores compared to those who encouraged themselves (p = 0.003). Preference for TBAs was most strongly affected by traditional beliefs (p < 0.001). On the contrary, preference for midwives was negatively correlated with traditional beliefs (p < 0.001).Conclusions: Parity was the factor influencing women's receiving less than the recommended four ANC visits during pregnancy. Women who were encouraged by their family to get ANC services had higher traditional beliefs score than women who encouraged themselves. Moreover, traditional beliefs followed by lower income families had the greater influence over preferring TBAs, with the opposite trend for preferring midwives. Increased attention needs to be given to the women; it also very important for exploring women's perceptions about health services that they received. © 2012 Agus and Horiuchi; licensee BioMed Central Ltd.


Tyastuti D.,Tokyo International University | Onishi H.,Tokyo International University | Ekayanti F.,State Islamic University of Jakarta | Kitamura K.,Tokyo International University
Journal of Interprofessional Care | Year: 2014

Complex health care needs in developing countries are stimulating development and implementation of interprofessional education (IPE). To better understand IPE, it is necessary to develop and evaluate an educational program that focuses on interprofessional learning (IPL) in Indonesia. However, no instrument in the Indonesian language has been developed to measure attitudes toward IPL. The aim of this study is to describe the process of a cross-cultural adaptation of the Readiness for Interprofessional Learning Scale (RIPLS) in an Indonesian version including determining its reliability and validity. The study was conducted among students enrolled in medical, nursing, pharmacy and public health courses at the State Islamic University, Jakarta, Indonesia, in 2012. The completed responses to RIPLS were collected from 755 students. The psychometric properties were analyzed by both exploratory factor analysis (EFA) and confirmatory factor analysis (CFA). EFA on 18-items revealed three factors accounting for 59.9% of the total variance. CFA resulted in a three-factor model over 16 items with satisfactory reliability (alpha coefficients >0.7), construct validity and acceptable indices of goodness of fit. We conclude that this Indonesian version of RIPLS with a three-factor model over 16 items is a valid tool to measure students' attitudes toward IPL. © 2014 Informa UK Ltd.


Subiyakto A.,State Islamic University of Jakarta | Bin Ahlan A.R.,International Islamic University Malaysia
International Conference on Research and Innovation in Information Systems, ICRIIS | Year: 2013

Although there has been significant research on information and communication technology (ICT) project success, but there are still gaps around this field. Thus, further understanding to ensure the level of ICT project success is still required in both theory and practice. The ultimate aim of this study is develops a coherent critical success factors (CSFs) framework for helping ICT project managers to deal with the complexity of project dimensions which have influenced the shaping of project success. The four consideration points in this framework development are: first, based on a comprehensive success definition as guidance for measuring the critical connection between the success criteria level and the CSFs level; second, integrating coherently four project dimensions for encouraging the high content validity; third, presenting the alternating critical connection between the project success definition and the CSFs determination; lastly, adopting the project stakeholder perceptions from multiple levels of an ICT project organization's environment. However, it is a proposition concept, but this proposed CSF framework is reasonable in the context of the ICT project success improvement. © 2013 IEEE.


Nurhayati,State Islamic University of Jakarta
2012 International Conference on Computer and Communication Engineering, ICCCE 2012 | Year: 2012

Hierarchical clustering algorithms are very important to increase the network's lifetime. In this paper we proposed Algorithm Routing Protocol based BCDCP and LEACH that called Inner Cluster Routing Protocol Wireless Sensor Network (ICRP), a new hierarchical clustering algorithm that have ability to create equal cluster with the same number of sensor like BCDCP method and then divided into small cluster with the same number of cluster like method in LEACH. In ICRP algorithm, the first step is deploying random of sensor node in field area, and then the sensor nodes will broadcast all information to the base station. Further, the base station compute variables to find the most efficient energy with a formula, called MER (Most of Efficient Energy Ratio). The sensor determine cluster by a message sent from the base station and save all information in information table message. This algorithm consists of three phases: initial, set-up and maintenance phase. The Simulation results shows that our algorithm reduce energy dissipation and prolong network lifetime compared with BCDCP and LEACH. The goals of this routing are to find the efficiency energy and to get balance energy consumption for prolong network lifetime. © 2012 IEEE.

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