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Ulrikh E.,State Educational Institution of Higher Education | Suhih S.,State Educational Institution of Higher Education | Dishluk L.,State Educational Institution of Higher Education | Avstrievskikh A.,State Educational Institution of Higher Education
Biology and Medicine | Year: 2015

This article studies the disintegration of capsule shells derived from plant analogs of pharmaceutical gelatin in buffer solutions with different indices of pH, and in the gastric and intestinal juices. The photos taken during analysis are presented. It was determined that the fastest dissolution of capsule shells from plant analogs of pharmaceutical gelatin occurs in gastric and intestinal juices. It was also found that in each solution's variants, the capsule shells had swollen. But in the case of gastric juice, the capsule shells were destroyed; the contents got out and made a slick on the surface of the solution. The highest degree of destruction was observed in gastric juice. These findings prove appropriateness of using the plant analogs of pharmaceutical gelatin for making soft capsules' shells, which are used in dietary supplements. These shells are readily soluble and digestible in stomach. It was also proved that during the destruction of shells derived from plant analogs of pharmaceutical gelatin, the shells acidify the solution. © 2015 Ulrikh et al. Source


Ulrikh E.,State Educational Institution of Higher Education | Kozlova O.,State Educational Institution of Higher Education | Dishluk L.,State Educational Institution of Higher Education | Arkhipov A.,State Educational Institution of Higher Education
Advances in Environmental Biology | Year: 2014

In production of soft capsules, natural and semi-synthetic vegetative analogues for pharmaceutical gelatin are used. This work is devoted to defining elemental composition of vegetative analogs for pharmaceutical gelatin using the electron probe microanalysis method. The electron probe microanalysis is one of the most popular methods of quantitative and semi-quantitative nondestructive elemental analysis. Spectrometric profiles are described for defining the composition of carboxymethylcellulose CMC Akutsel 3265; cognac gum; pectin ARA 105; sodium alginate NO4-600. According to the results of spectrophotometric profile analysis, mass fraction of chemical elements (oxygen, nitrogen, carbon, sodium, chlorine) was estimated. © 2014 AENSI Publisher All rights reserved. Source

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