Chang H.-C.,Chung Shan Medical University |
Huang C.-N.,Chung Shan Medical University |
Yeh D.-M.,Chung Shan Medical University |
Wang S.-J.,STANDARD Foods Co. |
And 2 more authors.
Plant Foods for Human Nutrition | Year: 2013
Obesity is associated with a great diversity of diseases including non-alcoholic fatty liver disease. Our recent report suggested that oat, rich in beta-glucan, had a metabolic-regulating and liver-protecting effect in an animal model. In this study, we performed a clinical trial to further confirm the effect of oat. Subjects with BMI ≧27 and aged 18-65, were randomly divided into a control (n = 18) and an oat-treated (n = 16) group, taking a placebo or beta glucan-containing oat cereal, respectively, for 12 weeks. Our data showed that consumption of oat reduced body weight, BMI, body fat and the waist-to-hip ratio. Profiles of hepatic function, including AST, but especially ALT, were useful resources to help in the evaluation of the liver, since both showed decrements in patients with oat consumption. Nevertheless, anatomic changes were still not observed by ultrasonic image analysis. Ingestion of oat was well tolerated and there was no adverse effect during the trial. In conclusion, consumption of oat reduced obesity, abdominal fat, and improved lipid profiles and liver functions. Taken as a daily supplement, oat could act as an adjuvant therapy for metabolic disorders. © 2013 Springer Science+Business Media New York.
Hsu B.Y.,National Taiwan University of Science and Technology |
Hsu B.Y.,University of Kang Ning |
Lu T.J.,National Taiwan University of Science and Technology |
Chen C.H.,National Taiwan University of Science and Technology |
And 2 more authors.
Food Chemistry | Year: 2013
Ginseng and lingzhi (Ganoderma lucidum) both are valuable traditional Chinese medicines and have been extensively utilised in functional foods and traditional medicines in many Asian countries. However, massive quantity of ginseng residue is produced after extraction of ginseng which still contains a lot of bioactive compounds such as ginsenosides. The goal of this study was to reuse the American ginseng extraction residue as the fermentation medium of G. lucidum to produce bioactive ginsenoside enriched biotransformation products. The changes of ginsenosides in the fermentation products were analysed during fermentation. Our results showed that after 30 days of fermentation, ginsenoside Rg1, Rd, and compound K (CK) significantly increased, especially Rd, while other ginsenosides (Re, Rb1 and Rc) decreased during fermentation. Ginsenoside Rd is the major ginsenoside in the final fermentation product. Furthermore, the biotransformation of ginsenosides was the major reaction in this fermentation process. © 2013 Elsevier Ltd.
Wang H.-C.,National Health Research Institute |
Hung C.-H.,Chung Shan Medical University |
Hsu J.-D.,Chung Shan Medical University |
Yang M.-Y.,Chung Shan Medical University |
And 2 more authors.
Journal of Cereal Science | Year: 2011
Recently, the incidence of colon cancer has been rapidly increasing in previously low-risk countries other than the Western world. Since dietary factors are thought to be key components involved in high risk colon cancer, the current trend for colon cancer prevention is toward dietary intervention. To explore if whole oat functions as a chemoprevention agent, an inflammation-related mouse colon cancer model, initiated with 1, 2-dimethylhydrazine (DMH), followed by dextran sodium sulfate (DSS), was performed to evaluate the preventive effect of whole oat containing diets. The result indicated middle and high dose whole oat diets significantly reduced the number of aberrant crypt foci (ACF) as well as colon tumors. Further, human colon carcinoma cells were subcutaneously inoculated into BALB/cAnNg-Foxn1 nude mice to measure the growth inhibition on whole oat diets. Low, middle and high dose whole oat diets significantly decreased the tumor volumes by 13%, 17% and 43%, respectively, indicating a dose dependent inhibitory effect. Meanwhile, 38% and 54% reductions in tumor weights were observed in middle and high dose whole oat diets. Together, the evidence suggests whole oat helps protect against colon cancer development and could be a good chemoprevention agent taken as a daily supplement. © 2010 Elsevier Ltd.
Standard Foods Corporation | Date: 2011-08-23
Standard Foods Corporation | Date: 2013-01-15
sunflower oil; rape flower oil, grape seed oil, plant oil, namely, olive oil, salad oil, corn oil, soybean oil, meat, meat extracts, namely, chicken extracts, peanut soup, red beans soup, mung beans soup, swallow-nests soup.