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Lupu V.V.,Grigore T. Popa University of Medicine and Pharmacy | Ignat A.,Grigore T. Popa University of Medicine and Pharmacy | Paduraru G.,Grigore T. Popa University of Medicine and Pharmacy | Mihaila D.,St Mary Childrens Emergency Hospital | And 2 more authors.
Medicine (United States) | Year: 2015

Heterotopic gastric mucosa (HGM) of the esophagus is a congenital anomaly consisting of ectopic gastric mucosa. It may be connected with disorders of the upper gastrointestinal tract, exacerbated by Helicobacter pylori. The diagnosis of HGM is confirmed via endoscopy with biopsy. Histopathology provides the definitive diagnosis by demonstrating gastric mucosa adjacent to normal esophageal mucosa. HGM located in the distal esophagus needs differentiation from Barretts esophagus. Barretts esophagus is a well-known premalignant injury for adenocarcinoma of the esophagus. Malignant progression of HGM occurs in a stepwise pattern, following the metaplasiadysplasia adenocarcinoma sequence. We present a rare case of a teenage girl with HGM located in the distal esophagus, associated with chronic gastritis and biliary duodenogastric reflux. Endoscopy combined with biopsies is a mandatory method in clinical evaluation of metaplastic and nonmetaplastic changes within HGM of the esophagus. © 2015 Wolters Kluwer Health, Inc. All rights reserved. Source


Straticiuc-Ciongradi I.,St Mary Childrens Emergency Hospital | Straticiuc-Ciongradi I.,Grigore T. Popa University of Medicine and Pharmacy | Olaru C.,St Mary Childrens Emergency Hospital | Olaru C.,Grigore T. Popa University of Medicine and Pharmacy | And 8 more authors.
Archives of Biological Sciences | Year: 2015

Iatrogenic esotracheal fistula in pediatric patients is an extremely rare complication, and appears either because of the pressure exercised by the tracheostomy cannula or in patients that are long-term bearers of esogastric tubes, which will cause, together with the cannula, ischemic injuries and necrosis of the tissue. The treatment of these lesions is controversial. The paper presents the management of a pediatric patient with an acquired esotracheal fistula, secondary to a tracheostomy. Source


Gimiga N.,St Mary Childrens Emergency Hospital | Gimiga N.,Grigore T. Popa University of Medicine and Pharmacy | Burlea M.,St Mary Childrens Emergency Hospital | Burlea M.,Grigore T. Popa University of Medicine and Pharmacy | And 4 more authors.
Archives of Biological Sciences | Year: 2015

The aims of this five-year retrospective study was to investigate the common etiologies, clinical, biological and pathological patterns of lower gastrointestinal bleeding in children from a hospital center in northeastern Romania. We included in the study 118 children with lower gastrointestinal hemorrhage or two consecutive positive fecal occult blood tests. Patients were divided into three age groups (0-2 years, 3-10 years, 11-18 years) and the findings were reported separately for each group. Gastrointestinal bleeding was more common among 3-10-year-old children. Hematochezia was the most common form of presentation (54.2%), followed by rectorrhagia (40.7%). Each patient underwent a colonoscopy with bioptic mapping. The most common colonoscopy finding was solitary colorectal polyps in 39 cases (33.1%), followed by suggestive aspects for ulcerative colitis in 26 patients (22.0%); only 15 (12.7%) were histologically confirmed. Endoscopic polypectomy was performed in all cases. We report two perforations and one hemorrhage that required surgery. Source

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