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Mirandola, Italy

Fini N.,University of Modena and Reggio Emilia | Georgoulopoulou E.,University of Modena and Reggio Emilia | Vinceti M.,University of Modena and Reggio Emilia | Monelli M.,University of Modena and Reggio Emilia | And 6 more authors.
Muscle and Nerve | Year: 2014

Introduction: We performed a population-based study to assess amyotrophic lateral sclerosis (ALS) survival after noninvasive ventilation (NIV), invasive ventilation (IV), and enteral nutrition (EN). Methods: We included patients diagnosed from 2000 to 2009 in Modena, where a prospective registry and a Motor Neuron Diseases Centre have been active since 2000. Results: Of the 193 incident cases, 47.7% received NIV, 24.3% received tracheostomy, and 49.2% received EN. A total of 10.4% of the patients refused NIV, 31.6% refused IV, and 8.7% refused EN. The median survival times after NIV, IV, and EN were 15, 19, and 9 months, respectively. Of the tracheostomized patients, 79.7% were discharged from the hospital; 73.0% were discharged to home. The median survival times for tracheostomized patients who were cared for at home and in nursing homes were 43 and 2 months, respectively. The multivariate analysis demonstrated that the place of discharge was the only independent prognostic factor after IV (P<0.01). Conclusions: Service organizations may promote adherence to NIV, IV, EN, and influence postprocedure survival. These data may be useful in defining health plans regarding advanced ALS care and in patient counseling. © 2014 Wiley Periodicals, Inc. Source

Bellasi A.,University of Bologna | Ferramosca E.,University of Bologna | Ratti C.,St Maria Bianca Hospital | Block G.,Denver Nephrology | Raggi P.,Emory University
Journal of Nephrology | Year: 2012

Background: Vascular and valvular calcifications are a common finding in chronic kidney disease (CKD) patients and are associated with increased morbidity and mortality. We investigated the hypothesis that calcification of the cardiac valves is a marker of coronary artery calcification (CAC) and thoracic aorta calcification (AoC) in hemodialysis (CKD-5) patients. Methods: This was a cross-sectional study of 145 maintenance CKD stage 5 (CKD-5) patients. All patients underwent electron beam tomography for quantification of CAC and AoC score via the Agatston score. The presence of calcification of the cardiac valves was assessed by standard bi-dimensional echocardiography. Results: Eighty-four of the study patients (58%) had echocardiographic evidence of valvular calcification. A significant and graded association between valvular calcification and CAC as well as AoC was detected. Patients with 1 or 2 calcified valves had a significantly greater likelihood of having a CAC score >1,000 (odds ratio [OR] = 5.94; 95% confidence interval [95% CI], 1.91-18.44; p=0.002; and OR=3.27; 95%CI, 1.36-7.88; p=0.007, respectively). Similarly, the presence of 1 or 2 calcified valves was associated with an eightfold and threefold increased probability of an AoC score greater than the third quartile, respectively. Conclusions: This cross-sectional analysis shows that calcification of the cardiac valves is closely associated with vascular calcification, an established marker of risk in prevalent hemodialysis patients. © 2011 Società Italiana di Nefrologia. Source

Andreani A.,St Maria Bianca Hospital | Cappiello G.,St Maria Bianca Hospital | Valli M.,St Maria Bianca Hospital | Businarolo E.,St Maria Bianca Hospital | And 3 more authors.
Clinical Respiratory Journal | Year: 2013

One of the known agent that causes an organizing pneumonia could be the chronic inhalation of food, but generally we can't find the specific food that caused this pattern. We show a case where, with an accurate medical history, supported by the various histological investigation steps, we could reach the specific cause of it. © 2013 John Wiley & Sons Ltd. Source

Andreani A.,St Maria Bianca Hospital | Rossi G.,Section of Pathologic Anatomy | Giovannini M.,St Maria Bianca Hospital | Cappiello G.F.,St Maria Bianca Hospital
Canadian Respiratory Journal | Year: 2012

Pulmonary actinomycosis is a rare disease frequently misdiagnosed, even by experienced clinicians, as primary or metastatic lung cancer or as other more conventional lung infections. It is often an unexpected disease that is basically detected only on cytological/histological examination. A case involving a patient who presented with a mass in the bronchial stump (of a previous pulmonary lobectomy) is described. Despite a strong suspicion of recurrent lung cancer, positron emission tomography confirmed a diagnosis of a suture-related bronchial actinomycosis. ©2012 Pulsus Group Inc. All rights reserved. Source

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