St. John Fisher College is a private liberal arts college located in Pittsford, New York, United States, an eastern suburb of Rochester. Fisher is ranked by U.S. News & World Report among the Doctoral Research Universities , which reflects the college's growth in the area of doctoral program offerings. It is named after St. John Fisher, the former Bishop of Rochester, in England. Wikipedia.
Amidon S.,St. John Fisher College |
Brown J.E.,St. John Fisher College |
Dave V.S.,St. John Fisher College
AAPS PharmSciTech | Year: 2015
Colon-specific drug delivery systems (CDDS) are desirable for the treatment of a range of local diseases such as ulcerative colitis, Crohn’s disease, irritable bowel syndrome, chronic pancreatitis, and colonic cancer. In addition, the colon can be a potential site for the systemic absorption of several drugs to treat non-colonic conditions. Drugs such as proteins and peptides that are known to degrade in the extreme gastric pH, if delivered to the colon intact, can be systemically absorbed by colonic mucosa. In order to achieve effective therapeutic outcomes, it is imperative that the designed delivery system specifically targets the drugs into the colon. Several formulation approaches have been explored in the development colon-targeted drug delivery systems. These approaches involve the use of formulation components that interact with one or more aspects of gastrointestinal (GI) physiology, such as the difference in the pH along the GI tract, the presence of colonic microflora, and enzymes, to achieve colon targeting. This article highlights the factors influencing colon-specific drug delivery and colonic bioavailability, and the limitations associated with CDDS. Further, the review provides a systematic discussion of various conventional, as well as relatively newer formulation approaches/technologies currently being utilized for the development of CDDS. © 2015, American Association of Pharmaceutical Scientists.
Lavigne J.,St. John Fisher College
Currents in Pharmacy Teaching and Learning | Year: 2012
Objectives: To assess learning outcomes of "Educating Pharmacists to Improve Quality" (EPIQ), an "off-the-shelf" curriculum funded by the Pharmacy Quality Alliance. Methods: EPIQ was delivered to P3 students (n = 63) and P2 students (n = 73) in 2009-2010. The Healthcare Quality Book was added in 2010. Descriptive statistics characterized changes in student self-reported outcomes on the EPIQ standardized survey. Results: Students reported better skills and knowledge after EPIQ yet rated as only "fair" to "good" their ability or motivation to pursue quality improvement. Use of The Healthcare Quality Book was associated with a significant improvement in students' ratings of the expected usefulness of EPIQ training in pharmacy practice. Conclusions: Tools and applications are our new focus, beginning with the migration of exercises to experiential courses. Future assessments will include demographic data and separate evaluations of the course, materials, and instructor. Survey items will be grouped by knowledge, attitudes, and skills. © 2012 Elsevier Inc.
News Article | November 21, 2016
Liz Mertz has been promoted to director of client services for Catalyst, a Rochester, New York-based marketing agency specializing in acquisition, retention, customer relationship management (CRM) and customer experience design (CX). A ten-year agency veteran, Mertz will lead the Catalyst account team in developing data-driven, customer-centric communications programs. Elizabeth (Liz) Mertz will serve as the new director of client services for Catalyst, a marketing agency specializing in acquisition, retention, CRM and CX. Formerly the agency’s senior account director, Mertz will lead strategy development for Catalyst clients, who include Valvoline Instant Oil Change, Preferred Mutual, Kroger, TTI Floor Care North America, and many others. “Liz has been a Catalyst rock star for more than ten years,” said Jim Dellavilla, chief client officer. “She’s successfully led the Valvoline Instant Oil Change account during all ten of those years and is a proven leader. She’s created dozens of profitable marketing programs for many Catalyst clients. We’re thrilled to offer her this new position.” Mertz holds a master’s degree in business administration and management from St. John Fisher College. She is an active volunteer with Meals on Wheels and tutors fourth graders at a Rochester area primary school. Mertz resides in Victor, New York with her husband and four children. Catalyst (www.catalystinc.com) is a marketing agency that helps clients develop more profitable customer relationships. We take the guesswork out of marketing decisions by combining our intellectual curiosity and inquisitiveness with hard-core analytics and measurement. It’s a powerful combination that improves our clients’ marketing, because it yields deeper insights that anticipate customers’ needs better. Headquartered in Rochester, NY, our clients include AAA, ACI Worldwide, American Family Insurance, Embrace Home Loans, Heraeus Kulzer, Kodak Alaris, Kroger, Preferred Mutual, Rise Broadband, TTI Floor Care North America, University of Rochester, Valvoline, and Xeikon, among others.
News Article | February 28, 2017
BOSTON--(BUSINESS WIRE)--Brook Venture Partners, a Boston-based growth equity firm is pleased to announce the promotions of Brennan Mulcahey, Jonathan Green and Kyle Stanbro to Partner. They join Partners and Board members Fred Morris, Ned Williams and Walter Beinecke, and Director of Finance and Operations Jenn Mosto, as members of the senior management team. The firm has also promoted Ryan Wittman and Amit Nagdev to Associate. Commenting on the promotions, Fred Morris said, “Brook has doubled its assets under management over the past five years while evolving its focus from earlier stage investments to control, growth equity investments in technology and technology-enabled service companies. These three upcoming Partners and two Associates have been integral to this growth and evolution of focus. I am very pleased to see the next generation of talent rise to the Partner level.” Brennan Mulcahey joined Brook in 2011 and focuses primarily on leading new investments in Healthcare Information Technology, B2B Software, and Tech-Enabled Services, working with companies that have a proven business model and are looking to accelerate growth through enhanced sales and marketing. Brennan serves on the Board of Directors of Brook portfolio company Medicine-On-Time and is a Board observer at seven Brook portfolio companies. Brennan earned his BA in Finance from the University of Rochester in three years and holds an MBA from the Simon School of Business at the University of Rochester. Jonathan Green joined Brook in 2004 and is the head of Investor Relations. Prior to joining Brook, Jonathan was Vice President of Investor Relations for Boston American Asset Management, Inc. where he launched the firm’s second fund, doubling assets under management. Previously he founded or turned around various technology firms including Crestec Los Angeles, Inc., Aurora Graphics, and Touchmark, Inc. He holds a B.S. in Business Administration from the Whittemore School of Business at the University of New Hampshire. Kyle Stanbro joined Brook in 2014 and is the head of the Financial Planning and Analysis team, working very closely with Brook’s portfolio companies to manage their financial reporting, analysis, and planning. He is also engaged in evaluating strategic acquisition opportunities for these companies as they arise. Prior to joining Brook, Kyle held financial management positions at Travelers and Kodak. Kyle earned his BS in Corporate Finance from St. John Fisher College in Rochester, NY and holds an MBA from the Simon Graduate School of Business at the University of Rochester, completing concentrations in Finance and Corporate Accounting. Ryan Wittman joined Brook in 2014 and works closely with several of Brook’s portfolio companies to help with their financial reporting, analysis and planning. Prior to Brook, Ryan worked as a Financial Analyst at CSM Corporation, a Minneapolis based Real Estate Acquisition Company. Ryan earned his BA in Applied Economics and Management from Cornell University and holds an MBA from Boston College with a specialization in Corporate Finance. Amit Nagdev joined Brook in 2015 and works closely with several of Brook’s portfolio companies to help with their financial reporting, analysis and planning. Prior to joining Brook, Amit held corporate finance positions at Liberty Mutual, Constellation Brands, and Remy Cointreau. Amit earned his BA from Bentley University, holds an MBA from the University of Rochester, and has completed all three levels of the CFA exam. Brook Venture Partners makes growth equity control investments in Information Technology and IT-enabled service companies located in the eastern United States. The firm focuses on initial acquisition investments of $2-15 million and specializes in both financing and providing the strategic and planning support necessary to effectively manage growth. Brook is headquartered outside Boston in Wakefield, MA. For more information on Brook Venture Partners, see www.brookventure.com.
Kraft B.M.,St. John Fisher College |
Brennessel W.W.,University of Rochester
Organometallics | Year: 2014
A series of neutral organosilicon compounds, R3Si(OPO) (R = Me (1), Et (2), Ph (3)), cis-R2Si(OPO)2 (R = Me (4), Et (5), iPr (6), tBu (7), Ph (9)), (CH2) 3Si(OPO)2 (8), and cis-R2Si(OPO)Cl (R = Me (10), Et (11)) (OPO = 1-oxo-2-pyridinone) have been prepared and fully characterized. X-ray crystallographic analyses show 1 to be tetracoordinate, 3, 7, and 10 to be pentacoordinate, and 4-6, 8, and 9 to be hexacoordinate. In the hexacoordinate structures, a mixture of diastereomers is observed in the form of C/N site disorder in each OPO ligand. Variable-temperature 13C and 29Si NMR studies indicate reversible Si←OC bond dissociation occurring in all pentacoordinate and hexacoordinate complexes to a varying degree with greater tendency toward dissociation in hydrogen-bonding donor solvents. Significant weakening of the dative Si←OC bond in 3 is observed in the cocrystallized adduct solvate 3·Ph3SiOH· 1/2C5H12, providing structural evidence for the decrease in coordination number of the OPO ligand by hydrogen-bonding donors. In the hexacoordinate complexes, increasing steric bulk of ancillary ligands also was found to promote dissociation. 1H and 13C VT-NMR studies of 4, 6, 8, and 9 indicate stereoisomerization equilibria concurrent with Si←OC bond dissociation proposed to occur through trigonal-bipyramidal intermediates. © 2013 American Chemical Society.
Bowllan N.M.,St. John Fisher College
Journal of School Health | Year: 2011
Background: This intervention study examined the prevalence of bullying in an urban/suburban middle school and the impact of the Olweus Bullying Prevention Program (OBPP). Methods: A quasi-experimental design consisting of a time-lagged contrast between age-equivalent groups was utilized. Baseline data collected for 158 students prior to implementation of the OBPP were compared to 112 students who received the OBPP intervention for 1 year. Multiple perspectives on bullying were collected using the Revised-Olweus Bully/Victim Questionnaire. Similarly, a teacher questionnaire collected data for 17 teachers on prevalence of bullying and capacity to intervene pre- and post- OBPP intervention. Descriptive and inferential statistics were generated to analyze findings. Results: Statistically significant findings were found for 7th grade female students who received 1 year of the OBPP on reports of prevalence of bullying (p = .022) and exclusion by peers (p = .009). In contrast, variability in statistical findings was obtained for 8th grade females and no statistical findings were found for males. Following 1 year of the OBPP, teachers reported statistically significant improvements in their capacity to identify bullying (p = .016), talk to students who bully (p = .024), and talk with students who are bullied (p = .051). Other substantial percentile changes were also noted. Conclusion: Findings suggest a significant positive impact of the OBPP on 7th grade females and teachers. Other grade and gender findings were inconsistent with previous literature. Recommendations for further research are provided along with implications for school health prevention programming. © 2011, American School Health Association.
Hunter R.,St. John Fisher College
Computers and Composition | Year: 2011
The collaborative affordances of the wiki, in conjunction with local literacy practices, have important implications for the development of contemporary online notions of authorship. Using discourse analytic methods focused on the talk pages of several World of Warcraft Wiki (WoWWiki) articles, this essay seeks to identify particular patterns of language use in the interactions between members of this online voluntary writing group in order to identify how contributors think about authorship in a clearly collaborative writing space. Candace Spigelman's (1998) theoretical construct of " habits of mind" and James Paul Gee (1989) theory of discourse are used to describe more or less effective ways of collaborating on writing in this context. The findings suggest the direction of this writing is toward much more collaborative and communal notions of authorship-ones in which the meaning of " collaborative" and " authorship" are being redefined. Successful collaborative writing on WoWWiki is a result of writers sharing common " habits of mind," and collaboration can be disrupted by those who hold more author-centric perspectives of textual ownership. © 2010 Elsevier Inc.
Oplinger M.,St. John Fisher College |
Andrews C.O.,St. John Fisher College
Annals of Pharmacotherapy | Year: 2013
OBJECTIVE: To investigate the evidence leading to nitrofurantoin contraindication in patients with a creatinine clearance (CrCl) below 60 mL/min. DATA SOURCES: Literature was searched in PubMed (1965-June 2012) by using the key words and MeSH terms urinary tract infections-drug therapy, chronic kidney insufficiency, kidney diseases, pharmacokinetics, safety, and efficacy, combined with nitrofurantoin. Articles were limited to the English language. References from the identified studies, Food and Drug Administration-approved product information packets, drug information resources, and pharmacology books were also reviewed. DATA SYNTHESIS: The contraindication of nitrofurantoin in patients with a CrCl below 60 mL/min was included in the product information packets sometime between 1988 and 2003. The 1988 Macrodantin product information indicated a CrCl cutoff level of 40 mL/min, but the current contraindication of less than 60 mL/min is found in the 2003 Macrobid product information. It is unclear when and why this change occurred, but it may have followed the work of Sachs and colleagues in 1968, who reported very little drug recovery in the urine of patients with a CrCl below 60 mL/min. This and previous studies have several and severe limitations, such as the inclusion of a small number of patients, an undefined or poorly defined method to determine CrCl and renal impairment, measurement of amounts of nitrofurantoin excreted in the urine instead of urinary concentrations, and most importantly, a lack of clinical efficacy end points. More recently, a chart review on clinical cure of urinary tract infections treated with nitrofurantoin provided grounds for further investigations on the utility of this drug for patients with a CrCl of 60 mL/min or lower. Concerns of increased risks of serious adverse reactions in patients with reduced renal function have further limited the use of nitrofurantoin. However, although not completely clear, these complications seem to be linked most often to prolonged treatment, genetic variability, and predisposition to hypersensitivity. CONCLUSIONS: Data supporting the contraindication of nitrofurantoin for patients with a CrCl less than 60 mL/min are nonexistent. Well-designed clinical trials with urinary concentration information and clinical end points on patients with various degrees of renal impairment are much needed. Until such a study becomes available, the limited data available would support considering using this drug in patients with a CrCl of 40 mL/min or higher. © 1967-2013 Harvey Whitney Books Co.
Van Cura M.,St. John Fisher College
Journal of School Health | Year: 2010
Background: This study sought to understand the relationship between school-based health centers (SBHCs) and academic outcomes such as early dismissal and loss of seat time (the time students are available in school to learn or to access support services).Methods: A quasi-experimental research design was used to compare rates of early dismissal and loss of seat time between students who received SBHC and traditional school nursing services and students who received only traditional school nursing services. This study was a secondary data analysis of 764 " walk-in" visits during a 3-week period in 2 urban high schools in western New York state. Both schools provided school nursing services, and 1 of the 2 offered the option to enroll in an SBHC.Results: SBHCs significantly reduced the number of early dismissals from school (p = .013) in a comparison with students who received school nursing services alone. Students not enrolled in an SBHC lost 3 times as much seat time as students enrolled in an SBHC. Race, gender, age, poverty status, and presence of a preexisting illness did not influence these findings.Conclusions: These findings suggest that SBHCs have a direct impact on educational outcomes such as attendance. Recommendations for further research include replication of this study to increase confidence in its findings and using early dismissal and loss of seat time as indicators of attendance to measure other health outcomes related to SBHCs and school nursing. © 2010, American School Health Association.
Agency: NSF | Branch: Standard Grant | Program: | Phase: | Award Amount: 111.88K | Year: 2012
In this collaborative project undergraduate students enrolled in senior-level analytical chemistry laboratory courses at St. John Fisher College and Kennesaw State University are creating two novel experiments that are being validated through Analytical Method Transfer (AMT). Students at one college develop the experimental method, standard operating procedures, and figures of merit (i.e., accuracy, precision, specificity, selectivity, sensitivity, repeatability, reproducibility, linearity, range, detection limit, quantitation limit, robustness, and ruggedness). The experiment is transferred to the partnering college to undergo method equivalency testing by students. The experiments involve the dissolution of pharmaceutical dosage forms with the development of dissolution curves (release rates). Using UV-Vis spectroscopy or HPLC methods, the students determine the concentration of the active pharmaceutical ingredient in the dissolution media. A statistical comparison of the figures of merit determines the success of the AMT. The transferred experiments and student-generated data are being developed into case studies that use POGIL exercises. The student learning outcomes related to the AMT are being assessed through a standard pre-test and post-test method using multiple choice and free-response questions. In addition, students at four other colleges are evaluating the developed POGIL activities but are not using instrumentation. The collected data will be used to determine whether the learning outcomes for students participating in a laboratory POGIL activity (with access to instrumentation) are equivalent to those for students participating in a classroom POGIL activity (with no access to instrumentation). Student interviews are being conducted to determine whether any learning gains in AMT may be attributed to the POGIL activities. The interview results provide contextual information allowing project staff to tailor the POGIL activities to the students experiences. Site visits also are being used to evaluate the fidelity of the implementation of the POGIL activities by documenting variables such as adherence to project goals and use of effective POGIL. The findings from the project are being disseminated through publications and presentations.
Intellectual Merit. The teaching of AMT places students at the forefront of the global learning environment in analytical chemistry. Students 1) use a new instrument, a dissolution tester, not currently available in most analytical chemistry laboratories, and 2) address the curriculum concept of AMT, which is conducted world-wide but not currently taught to undergraduates. This engages both students and faculty in the discovery of acceptance criteria for an AMT based on figures of merit.
Broader Impact. This project is designed to facilitate adaptation of a new laboratory experiment at other sites and promotes a collaborative effort of an inter-institutional faculty-student partnership. The results are being disseminated broadly, helping to build a STEM education community. The technical skills of students are being broadened, enabling them to become competitive in the global market place.