Flynn A.,St Jamess Hospital Dublin |
Burke N.,St Jamess Hospital Dublin |
Byrne B.,The Coombe Women and Infants Maternity Hospital |
Gleeson N.,St Jamess Hospital Dublin |
And 2 more authors.
Obstetric Medicine | Year: 2015
Generalized pustular psoriasis of pregnancy is a rare dermatosis with potential serious consequences for both the mother and fetus. Treatment is difficult and historically steroids were the mainstay of treatment. Cyclosporin has been used for a few cases resistant to steroids. We report our own experience of two cases of generalized pustular psoriasis of pregnancy. Cases of generalized pustular psoriasis of pregnancy need review by a dermatologist with experience of skin disorders in pregnancy. Both the fetus and mother need to be monitored closely when systemic illness occurs, as there is a risk of stillbirth. Maternal sepsis is a known complication of generalized pustular psoriasis of pregnancy. Cyclosporin, when used appropriately is effective and relatively safe. © 2016, © The Author(s) 2016.
Laird E.,Trinity College Dublin |
Shannon T.,St Jamess Hospital Dublin |
Crowley V.E.F.,St Jamess Hospital Dublin |
Healy M.,St Jamess Hospital Dublin
Irish Journal of Medical Science | Year: 2016
Context: There have been few published reports of visualising vitamin D status at a micro level, i.e., within large individual urban centres of countries. Objective: To produce a visual map of the vitamin D status [25-hydroxy vitamin D—25(OH)D] of a large urban centre (n > 350,000) incorporating the regions of Dublin city that constitute the general practitioner catchment area of a large academic teaching adult hospital. Design, setting and participants: An observational investigation of 5287 free living Irish adults (>18 years). Results: Approximately, 15.2 % of those sampled in the winter period (October–February) were vitamin D deficient (<30 nmol/L) compared with 10.8 % of those sampled in the summer period (March–September). Vitamin D tests requested from the most social economically deprived urban locations (Dublin 8 and Lucan postal districts) had the highest rates of deficiency (23.5 and 20.4 %, respectively, both seasons). On average, females had a significantly higher 25(OH)D concentration compared with males (57.9 vs 52.3 nmol/L, respectively), while the younger participants (18–50 years) mean 25(OH)D concentration was 27 % lower in winter and 20.7 % lower in summer in comparison with the older participants (>50 years) (P < 0.0001). Conclusions: For the first time in Ireland, a visual depiction of data can be used to aid in the rapid identification of vitamin D status trends within a major urban area. These findings provide useful data to help inform public health policy regarding endemic vitamin D insufficiency to help target the population groups and resident location areas most at risk. © 2016 Royal Academy of Medicine in Ireland