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Agarwal J.,SRMS Institute of Medical science | Sharma R.,SRMS Institute of Medical science | Kumar V.,SRMS Institute of Medical science
Clinical Rhinology | Year: 2016

Background: The nose is the most prominent feature on the face, giving it an exaggerated importance than other facial features. Many people have some complaints about the shapes of their noses. There is increasing interest in cosmetic rhinoplasty in recent times, but reports of anthropometric measurements of the Indian population are limited. Aims: The objective of this survey was to provide anthropometric data for reconstructive and cosmetic surgery, and medical esthetics. Materials and methods: A random sample of medical students of both the sexes between the ages of 18 and 25 years from our medical college was obtained for this study. We measured the nasal height, nasal width, and anatomical nasal index. We also inquired about the degree of satisfaction and, in case of dissatisfaction, what an individual wants with his/her nose. The data were analyzed statistically. Results: Nasal indices were leptorrhine type and showed sexual dimorphism (female vs male: 60.44 vs 67.79). Most of the individuals were satisied with their nose. Those unsatisied had larger nasal indices and wanted smaller noses. Conclusion: This study can help in understanding the need of those who want a more “shapely” nose and can contribute to satisfactory results of cosmetic and reconstructive nasal surgery, anthropology, and forensic medicine. © 2016, Jaypee Brothers Medical Publishers (P) Ltd. All rights reserved.

Kumari A.,SRMS Institute of Medical science | Agrawal S.C.,SRMS Institute of Medical science
Pakistan Paediatric Journal | Year: 2013

Chronic or progressive ataxia in children may be caused by a number of conditions, including brain tumors, malformations and hereditary disorders.We report here a case of a 5 year old boy who presented with ataxia and developmental delay and on investigation was found to be a case of Joubert syndrome. MRI of the brain shows the characteristic molar tooth sign. Although, Joubert syndrome is not a common condition, yet it has clinical features which are very commonly found; that is why a high index of suspicion is needed, as such children are frequently misdiagnosed.

Agrawal S.C.,Muzaffarnagar Medical College | Agrawal S.C.,Formerly at SRMS Institute of Medical science | Kumari A.,SRMS Institute of Medical science
Indian Journal of Community Health | Year: 2014

Background: Despite the ongoing National Immunization Program, the immunization coverage in our country remains unsatisfactory, particularly in U.P.; moreover, a wide disparity is seen in the immunization coverage of children at different ages. Objectives: The present study was conducted to know the immunization status of children, up to the age of 6 years, and particularly to evaluate the same with regard to the age of the child. Methods: The present study was carried out as a cross sectional study, between September, 2012 and May, 2013 at the pediatric OPD of SRMS Institute of Medical Sciences, Bareilly. A total of 1000 children, aged up to 6 years were included. Immunization status with regard to the doses of BCG, OPV, DPT, DT and measles vaccine given at different time was assessed by interviewing parents and checking immunization cards. An endeavor was also made to know the various factors responsible for incomplete or no immunization through interviewing parents. Results: Over all, number of children with complete, partial and no immunization were 41.4%, 44.8% and 13.8% respectively. An inverse correlation exists between the age of the child and the vaccine acceptability - lesser the age, better is the coverage. Besides, a selective pattern is seen, the OPV-1 being the most preferred and DT booster (5-6 years) as the least preferred vaccine. Conclusions: There is need for improving the immunization coverage, particularly for the older children for reducing the burden of vaccine preventable diseases.

Subhanshu K.,SRMS Institute of Medical science | Sharma R.,SRMS Institute of Medical science | Sharma V.K.,SRMS Institute of Medical science
Indian Journal of Otology | Year: 2015

Background: Chronic suppurative otitis media is one of the common causes of deafness in India and occupies a considerable amount of clinic and operating time of otolaryngologists. Materials and Methods: This was a prospective study containing 50 patients, which was further divided into two groups of 25 patient each. One group was cartilage palisade technique group and other was temporalis fascia technique group (TFT group). Detailed history and examination along with pure tone audiometry was performed. Pre-and postoperative hearing results and graft uptake were compared. All surgeries were performed through the post aural approach. Cartilage was harvested from cymba concha and fascia from temporalis muscle. Results: Hearing improved significantly when either of the technique was used. Though this was slightly better, but stastically insignificant in TFT. there was no significant difference in the graft uptake rates, but it was better in cases of Eustachian tube dysfunction when cartilage palisades were used. Conclusion: There was no statistically significant difference in results in terms of success and auditory function but cartilage palisade technique gave better results in specific conditions like Eustachian tube dysfunction.

Sharma R.,SRMS Institute of Medical science | Sharma V.K.,SRMS Institute of Medical science
Indian Journal of Otology | Year: 2012

Background: Chronic suppurative otitis media (CSOM) still remains a major cause of conductive hearing loss in our country. On contrary a few patients also display an added sensorineural component. Materials and Methods: Hundred patients with unilateral CSOM undergoing ear surgery at our department were included in the study. The affected ears formed the ′CSOM group′ and the normal ears formed the ′Control group′. Detailed otologic history, clinical, surgical, and audiometric findings were recorded and analyzed. Results: It was inferred that though CSOM is associated with sensorineural (SN) loss in small majority of patients only. No co-relation was established between the duration of discharge and SN loss. Conclusions: Though, greater SN loss was seen in patients of CSOM with cholesteatoma but it was not statistically significant. It can be further studied that whether an early surgery in CSOM can prevent SN loss or not.

Baliarsingh S.,SRMS Institute of Medical science | Sharma N.,SRMS Institute of Medical science | Mukherjee R.,SRMS Institute of Medical science
Archives of Physiology and Biochemistry | Year: 2013

Context: Serum uric acid (SUA) has been known to be associated with cardiovascular diseases. "Atherogenic index of plasma" (AIP) is considered a very sensitive predictor of future cardiovascular events. Objectives: This study was conducted to analyse the association of AIP with SUA and various other lipid parameters. Methods: Parameters were measured on a fully automated analyser using standard reagent kits in a retrospective study involving 248 male Indian subjects between 40 to 59 years of age. Results: AIP correlates: moderately with TC/HDL-C (r = 0.47, p < 0.0001); to a lesser extent but comparably (r = 0.2, p < 0.01) with SUA, LDL-C/HDL-C and TC; negligibly with LDL-C and age. Discussion and conclusion: As SUA is positively associated with AIP it can be used as a supplementary marker for atherosclerosis/CVD in upper-middle-aged men. © 2013 Informa UK, Ltd.

Sharma N.,SRMS Institute of Medical science | Baliarsingh S.,SRMS Institute of Medical science
Archives of Physiology and Biochemistry | Year: 2012

Background: Atherogenic index of plasma, a newly emerging lipid parameter, has been employed only in a few studies in diabetics and not at all in non-diabetics. Methods: Association between fasting serum glucose and lipid parameters in 321 non-diabetic males aged 30 to 60 years was studied retrospectively. Glucose and lipid parameters were measured on fully automated analyser using standard reagent kits. Body mass index was also ascertained. Results: On comparing the various lipid parameters between normo-glycaemic and pre-diabetic men, a significant increase in TG (p = 0.0328), VLDL-C (p = 0.0328) and AIP (p = 0.0373) was observed only in pre-diabetic men ≥ 45 years. In non-diabetic men ≥ 45 years a slight but statistically positive correlation between glucose and AIP was also seen. Conclusions: Increased blood glucose in men ≥ 45 years, even in the non-diabetic range is associated with increased risk of CVD, as indicated by an increased atherogenic index of plasma. © 2012 Informa UK, Ltd.

Srivastava R.D.,SRMS Institute of Medical science | Kumar M.,SRMS Institute of Medical science | Shinghal R.,SRMS Institute of Medical science | Sahay A.P.,SRMS Institute of Medical science
Indian Journal of Physiology and Pharmacology | Year: 2010

Cold pressor test (CPT) is a simple and well documented laboratory test to evaluate the propensity for hypertension and sympathetic autonomic functions. Role of sex hormones was tested in the present study for the cold pressor response (CPR) in young adults of both sexes and in elderly population. The subjects comprised of young male (n=55), female (n=32) medical students of 17-25 years and elderly males (n=39) and females (n=25) of 50-70 years of age. The CPT was carried out in young and elderly males and females with one minute immersion of one hand in ice cold water (0-4°C). Both in young males and females the absolute rise in SBP and DBP in response to Cold pressor test (CPT) was highly significant, with diastolic percent rise exceeding systolic. In comparison to young males, the females showed greater percent rise in SBP and DBP. Similarly, in elderly groups of both sexes, CPR was associated with significant absolute rise in SBP and DBP with diastolic percent rise more than systolic in males only. Both in young versus elderly males and young versus elderly females comparison yielded comparable percent rise in SBP and DBP. The SBP and DBP percent rise was again comparable between elderly males and females. The greater responsiveness to CPT in young females could be attributed to increased pain sensitivity to cold, and/or genetic and hereditary factors overwhelming the hormonal protection offered by estrogen and nitric oxide (NO).

Kumari A.,SRMS Institute of Medical Science | Agrawal S.C.,SRMS Institute of Medical Science
Journal of Pediatric Neurosciences | Year: 2011

Pneumocephalus is a rare condition, characterized by the presence of gas in the cranial cavity, resulting from trauma, tumors and surgical or diagnostic procedures. Intracranial infection, without any predisposing factor like trauma or surgical intervention as a cause of pneumocephalus is relatively uncommon. While, intracranial infections by gas producing organisms as a cause of pneumocephalus are well known, a spontaneous intracranial infection caused by Staphylococcus aureus causing pneumocephalus is little known. We report here a child who developed pneumocephalus following staphylococcal lung infection with meningitis and eventually showed complete recovery. Meningitis should be considered as a possible cause of pneumocephalus in absence of trauma and surgical intervention.

Kumar M.,SRMS Institute of Medical science | Narayan J.,SRMS Institute of Medical science | Verma N.S.,University of Lucknow | Saxena I.,SRMS Institute of Medical science
Indian Journal of Physiology and Pharmacology | Year: 2010

Gender differences in pain perception have been reported in literature. However, most such studies have ignored the role of female sex hormones in influencing pain response across menstrual cycle (MC). In this study, we have investigated the variation in pain response on different days of the menstrual cycle. Ninety subjects (60 females) were subjected to experimental pain of cold pressor task, on days 1, 7, 14, and 21 of the MC (females), and on four consecutive Mondays of a month (males). Male subjects showed no variation in pain response. Females reported higher pain sensitivity on days 7 and 14 of MC. We suggest that experimental pain studies involving female menstruating subjects should be carried out only during a particular phase of the cycle, and this phase should be reported in literature to increase the reproducibility of the experiment.

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