Tel Aviv, Israel
Tel Aviv, Israel
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The present invention relates to a new composition, containing boric acid and a mixture of at least two lactobacilli selected from L. rhamnosus, L. crispatus, L. jensenii and L. gasseri. The present invention further relates to the use of the above composition in the treatment of fungal and/or bacterial vulvovaginitis.


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: MG-1.1-2014 | Award Amount: 5.71M | Year: 2015

This project will focus on the development of technologies and methodologies which have the potential to save costs and time across the whole life cycle of the aircraft (design, production, maintenance, overhaul, repair and retrofit), including for certification aspects. Moreover it will also target the integration of additional functions or materials in structural components of the aircraft, the increased use of automation. The first proposed step is the introduction of the -TiAl alloy, a well known promising advanced material for aerospace applications and a revolutionary manufacturing technology. Its specific stiffness and strength, as compared to its low weight, potentially leads to large weight savings (50%), and therefore lower mechanical loads on thermomechanical stressed parts, compared to the common Ni based superalloys. The integration of new material and new manufacturing technology will positively impact several aspects of the manufacturing and maintenance chain, starting from the design, the production, the repair). The aim of this project is twofold: - On one side the work will be focused on the development and integration at industrial of a IPR protected gas atomization process for producing TiAl powders, whose properties must be highly stable from batch to batch. Thanks to the stability of the chemical and granulometric properties of the powders, the application of the Rapid Manufacturing technique to the production of TiAl components will be economically affordable. While this technique is by now well-known, its main drawback resides in the scarce quality of the starting powders. - The other main drawback for the wide industrial application of TiAl components is the integrated optimisation of all the machining steps, that means the setting up of machine tool characteristics and parameters, cutting tool geometry, substrate and coating materials, advanced lubrication technologies.


Grant
Agency: European Commission | Branch: FP7 | Program: CP-TP | Phase: FoF.NMP.2013-11 | Award Amount: 7.51M | Year: 2013

The aim of the project is to develop a completely new manufacturing system for the volume production of miniaturised components by overcoming the challenges on the manufacturing with a wide range of materials (metallic alloys, composites, ceramics and polymers), through: (i) developing a high-throughput, flexible and cost-efficient process by simultaneous electrical-forming and electric-fast-sintering (Micro-FAST); (ii) scaling up the process to an industrial scale; (iii) further developing it towards an industrial production system for micro-/nano-manufacturing. These will be enabled/supported by developing: (i) a new machine concept: Micro-FAST CNC Machine; (ii) an innovative inline monitoring and quality inspection system; (iii) innovative multiscale modelling techniques for the analysis of the micro-structural behaviours of materials and its interactions with the production processes; (iv) new tooling techniques for high-performance tools, and (v) high-performance nano-material systems. The whole development will take into account energy savings, cost and waste reduction, and recycling issues which will be studied thoroughly through an expertise Life-Cycle Assessment. The development should lead to substantial improvements in the manufacture of components at micro and nanoscale with a good balance on cost and performance. The consortium seeks: reduction of the overall manufacturing cost by 50-100%; energy consumption by more than 30-50%; achieving full-density (100% density) components; direct economic gains for the SME participants of up to 5-25%. The whole development will support the EU-wide product innovations involving use of miniature and micro-components in many manufacturing sectors and, especially with difficult-to-cut and difficult-to-form materials. Adopting the production system in industry should help the EU manufacturing sectors to gain new technological and business competiveness significantly.


Grant
Agency: European Commission | Branch: H2020 | Program: CSA | Phase: EE-04-2014 | Award Amount: 1.43M | Year: 2015

The Train-to-NZEB project is designed to establish a functioning network of training and consultation centres (Building Knowledge Hubs, BKHs), providing practical trainings, demonstrations and complex consulting services for the implementation of nearly-zero energy buildings (NZEB). Using the improved training facilities, the BKHs will provide enhanced capacity for conduction of trainings on curricula developed on BUILD UP Skills II, thus reaching a significant number of workers not covered by the initiative. Additionally, BKHs will offer trainings for highly-qualified building professionals and demonstrations for non-specialists with decision-making authority, which, combined with administrative and financial consultancy service, will result in increased capacity for implementation of NZEB projects in the involved countries. In order to reach this goal, the following objectives are set: 1. Development of publicly available Terms of Reference for the setting up of the BKHs; 2. Adaptation of existing and development of new training programs; 3. Actual setting up of 4 training and consultation centres (BKHs) according to the Terms of Reference; 4. Building of internal capacity through train-the-trainer activities, targeting at least 90 qualified trainers; 5. Actual training courses according to annual training plans, resulting in: (a) 120 training courses for construction workers, targeting additional qualification of 2400 trainees; (b) 24 training courses for highly-qualified building specialists, targeting additional qualification of 480 trainees; (c) 36 training courses for non-specialists, targeting additional qualification of 720 trainees; 6. Strict monitoring and evaluation for constant improvement of the offered services. 7. Setting up of a web-based networking platform providing facilities for knowledge sharing and exchange between the BKHs; 8. Conduction of a targeted dissemination and communication campaign to increase the market demand for NZEB projects.


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: SC5-09-2016 | Award Amount: 5.08M | Year: 2016

NAIAD aims to operationalise the insurance value of ecosystems to reduce the human and economic cost of risks associated with water (floods and drought) by developing and testing - with key insurers and municipalities - the concepts, tools, applications and instruments (business models) necessary for its mainstreaming. We will do this in detail for 8 demonstration sites (DEMOs) throughout Europe and develop tools and methods applicable and transferable across all of Europe. The assumption is that Natural Assurance Schemes can reduce risk, especially to drought and flooding, and this risk reduction can be assessed and incorporated within insurance schemes. NAIADs conceptual frame is based on three pillars: (i) to help build a resilience approach to risk management through nature based solutions, (ii) the operationalisation and testing of scientific methods using a source-to-sea in DEMOs, (iii) the uptake of nature based solutions that are cost-effective and provide environmental, social and economic benefits. Trans-disciplinarity and stakeholder engagement are at the core of NAIAD for two reasons: first, because the conceptual and assessment methodologies combine physical, social and cultural and economic aspects, integrated into tools and methods but second, and most importantly road tested and validated with the stakeholders and end users themselves at the DEMOs. NAIAD will contribute to providing a robust framework for assessing insurance value for ecosystem services by (i) enabling full operationalisation through improved understanding of ecosystem functionality and its insurance value at a broad range of scales in both urban and rural context; (ii) making explicit the links between ecosystem values and social risk perception; and (iii) the application of developed methods and tools in water management by relevant stakeholders, especially businesses, public authorities and utilities.


Grant
Agency: European Commission | Branch: FP7 | Program: CP-TP | Phase: NMP.2013.4.0-3 | Award Amount: 5.97M | Year: 2013

Environmental wellbeing backed by increasingly severe legislation dictates that pollution and energy consumption by automobiles must be reduced significantly. The outcomes of this project will enable both these imperatives to be achieved simultaneously. The project aim is to establish production lines in Europe that manufacture components for lightweight complex-shaped automobile body structures that are significantly lighter and of comparable strength and stiffness to those currently available. This will be achieved by exploiting a new patented thermo-mechanical processing technology (HFQ) for sheet aluminium alloy that enables, for the first time, parts in heat treatable alloys to be produced to net-shape with maximum attainable mechanical properties. The life-cycle energy consumption of automobiles will be reduced; in the production stage, by the low energy requirements of HFQ, which is enhanced by the potential use of low cost recycled raw material and in the driving stage, by the reduced fuel consumption associated with lightweight vehicles. Reduced pollution is a natural corollary of low energy consumption. Exploitation of this groundbreaking technology will be achieved through refinement of its laboratory scale development by university, research institution and manufacturing SME collaboration, leading to production lines being established in Tier 1 companies. Two such lines are anticipated as an outcome of the project. In 8 year period, over 30 production lines will be established in Europe and over 1000 jobs could be created. It is expected that new Al-alloy body and chassis structures will be produced in a mass-production scale, with weight saving of over 40% for the Classes C&D and above segment vehicles (which are currently made of steel). Thus, 60% of cars could be made with Al-body and chassis structures, and the resultant fuel saving in car usage would be up to 23% on average.


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: NMBP-08-2016 | Award Amount: 8.00M | Year: 2016

The overall aim of LoCoMaTech is, in the first place, to enable the novel HFQ process, (patented by ICL) in its latest most advanced form, which includes 10 recently patented refining technologies (TRL4), to be used for the manufacture of lightweight, high strength body and chassis structures and components for low-cost vehicles, by establishing a prototype, full scale pilot production line (TRL6), supported by a supply chain ranging from raw material to end of life. This will be the first low-cost technology in the world enabling manufacture of high-strength lightweight complex-shaped aluminium parts and low environmental impact. The 1st generation of HFQ technology has already been commercially used in manufacturing 4 types of niche vehicles. This project aims at bringing the materials and manufacturing cost significantly down, through introducing newly patented technological measures, by which the technology could be used for producing low-cost vehicles. The low-cost HFQ technology will be used first for mass production of aluminium car body and chassis structures (eventually for all vehicles), which will lead to substantial improvement in energy efficiency, performance and travel range of low-end vehicles. LoCoMaTech will construct a world first low-cost HFQ aluminium production line (prototype), targeting reduction of energy consumption per vehicle by 15.3-22%, and cost-effective weight savings from 8.55 to 2.16 /kg-saved and improvement of LCA environmental impact by 15.39-26.8%. LoCoMaTech plans to assist in creating 53 commercial production lines and 1700 jobs, in year 6 from the completion of the project. The potential market for low-cost HFQ technology for passenger cars alone is over 160 billion pa, and double this, if buses, trucks, trains and aircraft are considered. This will create huge wealth for Europe and place European automotive industry in a world leading position for lightweight manufacturing technologies for low-end vehicle production.


Grant
Agency: European Commission | Branch: H2020 | Program: MSCA-ITN-ETN | Phase: MSCA-ITN-2014-ETN | Award Amount: 3.84M | Year: 2015

MUltiSectoral Integrative approaches to CArdiac care MUSICA - is proposed by a team of universities, companies and hospitals from 4 EU countries (Italy, United Kingdom, The Netherlands, Belgium). The main scope of MUSICA is to structure a new trans-sectoral and multidisciplinary network capable of developing research and technology with no barriers between academia, industries and clinicians in the cardiac arena, and of shaping young researchers with a novel and truly multidisciplinary mindset, capable of developing clinical- and business-oriented technology including tools for the advancement of base knowledge. MUSICA activity will impact on the field of cardiac surgery in three ways: i) from a scientific standpoint, new knowledge will be gained regarding the response of tissues to their surgical reshaping, to the implantation of devices and to drugs; ii) from a technological standpoint, new technologies will be developed to improve the design and generation of new clinical solutions, the clinical training, and image-based diagnosis and prognosis; iii) from an educational standpoint, a new paradigm of PhD track will be implemented, which will combine academic research in the field of biomedical engineering with industrial research activities and with on-the-field activity within clinical infrastructures. This novel PhD track will be accessed by 15 Early Stage Researchers (ESRs) recruited in the project by universities (7) and companies (8).


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: FoF-08-2015 | Award Amount: 4.00M | Year: 2015

The advances in the Information and Communication Technologies are revolutionizing our everyday life. However, the manufacturing industry does not yet take complete advantage of this huge potential. Using the latest ICT developments, MC-SUITE project wants to boost the productivity of manufacturing industry. On the one hand, machining process modelling empowered by High Performance Computing technologies allows simulating precisely the cutting process including force and surface quality. On the other hand, monitoring of the machine empowered by Big Data and Cloud technologies allows analysing the real process including vibration and process instability issues. Bridging the gap between virtual and real worlds, correlations of the simulated and monitored cutting process will allow optimizing both simulation and machining performances. In agreement with the work programme, the combination of manufacturing technologies and ICT is at the core of the construction of this consortium. The project will complement science with innovation to propose new software frameworks which can collect information from multi-monitoring devices as turnkey technologies to improve the machining process. MC-SUITE will produce multiple impacts in the European industry, reflecting the trans-disciplinary nature of the project. The participation of industrial partners, both SMEs and large companies from ICT and industrial sectors, will ensure that the project will directly impact on wide range of industries such as metal part manufacturing, Computer-Aided Manufacturing software, machine tool industry. MC-SUITE project has the opportunity to produce a new breakthrough in the productivity of the European manufacturing industry.

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