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Kudur M.H.,Srinivas Institute of Medical science and Research Center
Indian Journal of Dermatology | Year: 2013

Cutaneous piloleiomyoma is a rare benign tumor of skin originating from skeletal muscle of arrector pili attached to hair follicle. It can be single or multiple, solitary piloleiomyoma are common over genitalia. Multiple cutaneous piloleiomyomas are rare and they can cause pain on exposure to cold or with emotional disturbance. The prognosis of cutaneous piloleiomyomas after surgical excision is good. Here, we present a rare case of generalized multiple cutaneous piloleiomyoma in a young male. © Indian Journal of Dermatology 2013. Source


Hegde S.V.,Srinivas Institute of Medical science and Research Center | Adhikari P.,Manipal University India | Nandini M.,Manipal University India | D'Souza V.,Manipal University India
Complementary Therapies in Clinical Practice | Year: 2013

This study sought to examine whether consumption of two low-calorie fruit/day for 3-months can effectively improve oxidative stress, anthropometry, blood pressure and glycaemic control in type 2 diabetes mellitus. Study involved 123 patients who were assigned to receive either standard care or with additional dietary therapy. Dietary intervention resulted in significant reduction in malondialdehyde, plasma glucose, glycated haemoglobin and improvement in antioxidants like vitamin C and reduced glutathione when compared to controls. Mean plasma levels of vitamin C increased by 64% (p < 0.001). There were no differences in waist circumference, waist-to-hip ratio, blood pressure, vitamin E and superoxide dismutase in the intervention group at follow-up. Diet rich in fruits can improve some antioxidants which are likely to reduce oxidative stress in type 2 diabetes. Regular consumption of fruits can lower the glycaemic status in these patients. The study supports the usefulness of plasma vitamin C as a biomarker for fruit intake. © 2012 Elsevier Ltd. Source


Vijaya M.,Srinivas Institute of Medical science and Research Center | Malathi M.,Father Muller Medical College | Shivashankara A.R.,Father Muller Medical College
Asian Pacific Journal of Cancer Prevention | Year: 2012

Background: This study was conducted to determine levels of lipid peroxidation and antioxidant vitamin status in patients with oral cavity and oropharyngeal cancer. Methods: The study group consisted of a total number of 80 subjects between the age 40-68 years, 40 with clinically and histopathologically proved cases of oral cavity and oropharyngeal cancer and 40 normal healthy, age and sex matched volunteers as controls. Levels of lipid peroxidation products as malondialdehyde (MDA) and antioxidant vitamins as vitamin A and vitamin C were estimated and compared between the two groups. Results: There was a statistical significant difference in the mean MDA, plasma vitamin A and vitamin C in the oral and oropharyngeal cancer patients compared with the healthy controls (p<0.0001). Conclusions: Lipid peroxidation (MDA) is higher and plasma antioxidant vitamins like vitamin A and vitamin C were lower in oral cavity and oropharyngeal cancer patients than healthy controls. Source


Menezes R.G.,Srinivas Institute of Medical science and Research Center
The Medico-legal journal | Year: 2012

It was a sad and emotional moment for the citizens of Mangalore, India when the "Dubai to Mangalore" Air India Express Boeing 737-800 flight IX-812 crashed at the Mangalore International Airport on 22 May 2010, killing 158 people on board. Identification of the victims was difficult as most of the bodies were charred beyond easy recognition. The practical problems faced by the legal authorities in identifying the charred victims in a populous and developing country like India are discussed in this paper. Source


Hegde S.V.,Srinivas Institute of Medical science and Research Center | Adhikari P.,Manipal University India | Kotian S.,Manipal University India | Pinto V.J.,Manipal University India | And 2 more authors.
Diabetes Care | Year: 2011

OBJECTIVE - To assess the effect of yoga on anthropometry, blood pressure, glycemic control, and oxidative stress in type 2 diabetic patients on standard care in comparison with standard care alone. RESEARCH DESIGN AND METHODS - The study involved 123 patients stratified according to groups with microvascular complications, macrovascular complications, and peripheral neuropathy and without complications and assigned to receive either standard care or standard care along with additional yoga for 3 months. RESULTS - In comparison with standard care alone, yoga resulted in significant reduction in BMI, glycemic control, and malondialdehyde and increase in glutathione and vitamin C. There were no differences in waist circumference, waist-to-hip ratio, blood pressure, vitamin E, or superoxide dismutase in the yoga group at follow-up. CONCLUSIONS - Yoga can be used as an effective therapy in reducing oxidative stress in type 2 diabetes. Yoga in addition to standard care helps reduce BMI and improve glycemic control in type 2 diabetic patients. © 2011 by the American Diabetes Association. Source

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