Srinakharinwirot University is a public university located in Bangkok, Thailand. The university was founded in 1949. It was named by King Bhumibol Adulyadej after his mother and is the leading Thai university in the field of education and fine arts. It is the first institution of higher education in Thailand to concentrate solely on teacher training. Built upon the basis of Advanced Teacher’s College and Educational College, Srinakharinwirot University has firmly established educational basis within democratic, Thai society. Six decades following the basis were well carried through principles and educational theories. Developments include changes in university management, from a practitioner’s college to a multi-science university or comprehensive university. For three decades, the multi-science university has aimed at applying multiple science to empower intellectual society by putting efforts in research and academic excellence. Srinakharinwirote University currently has two campus:Prasarnmit Campus, BangkokOngkharak Campus, Ongkharak district, Nakhon Nayok Province Wikipedia.
Saiyudthong S.,Srinakharinwirot University |
Marsden C.A.,University of Nottingham
Phytotherapy Research | Year: 2011
Bergamot essential oil (BEO), Citrus aurantium subsp. bergamia (Risso) Wright & Arn. (Rutaceae), is used widely in aromatherapy to reduce stress and anxiety despite limited scientific evidence. A previous study showed that BEO significantly increased gamma-aminobutyric acid levels in rat hippocampus, suggesting potential anxiolytic properties. The aim of this study was to investigate the effect of BEO (1.0%, 2.5% and 5.0% w/w) administered to rats on both anxiety-related behaviours (the elevated plus-maze (EPM) and hole-board tests) and stress-induced levels of plasma corticosterone in comparison with the effects of diazepam. Inhalation of BEO (1% and 2.5%) and injection of diazepam (1 mg/kg, i.p.) significantly increased the percentage of open arm entries on the EPM. The percentage time spent in the open arms was also significantly enhanced following administration of either BEO (2.5% and 5%) or diazepam. Total arm entries were significantly increased with the highest dose (5%), suggesting an increase in locomotor activity. In the hole-board test, 2.5% BEO and diazepam significantly increased the number of head dips. 2.5% BEO and diazepam attenuated the corticosterone response to acute stress caused by exposure to the EPM. In conclusion, both BEO and diazepam exhibited anxiolytic-like behaviours and attenuated HPA axis activity by reducing the corticosterone response to stress. Copyright © 2010 John Wiley & Sons, Ltd.
Chittasupho C.,Srinakharinwirot University
Therapeutic Delivery | Year: 2012
Multivalent interactions of biological molecules play an important role in many biochemical events. A multivalent ligand comprises of multiple copies of ligands conjugated to scaffolds, allowing the simultaneous binding of multivalent ligands to multiple binding sites or receptors. Many research groups have successfully designed and synthesized multivalent ligands to increase the binding affinity, avidity and specificity of the ligand to the receptor. A multimeric ligand is a promising option for the specific treatment of diseases. In this review, the factors affecting multivalent interactions, including the size and shape of the ligand, geometry and an arrangement of ligands on the scaffold, linker length, thermodynamic, and kinetics of the interactions are discussed. Examples of the multivalent ligand applications for therapeutic delivery are also summarized. © 2012 Future Science Ltd.
Nitayaphat W.,Srinakharinwirot University
Materials Today: Proceedings | Year: 2017
The adsorption performance of chitosan beads was investigated after coffee residue blending for the removal of Reactive Red 152 as an anionic dye. The study of the dye removal of chitosan/coffee residue composite beads as a function of coffee residue concentration indicated that mass ratio of chitosan to coffee residue of 60/40 was the most useful for enhancing the dye removal. The effects of contact time, initial pH, and adsorbent dosage on the adsorption efficiency were investigated systematically. The equilibrium adsorption isotherm of chitosan/coffee residue composite beads exhibited better fit to the Langmuir isotherm model than to the Freundlich isotherm model. The maximum adsorption capacity of composite bead was 4.27 mg/g. The dye desorption of composite bead was 24.83%. SEM images confirm that after adsorption the dye were dispersed onto the composite bead surface. This study demonstrated that the chitosan/coffee residue composite can effectively remove reactive dye from aqueous solution and simply with low cost. © 2017 Elsevier Ltd. All rights reserved.
Nitayaphat W.,Srinakharinwirot University
Chiang Mai Journal of Science | Year: 2014
Chitosan/bamboo charcoal composites were prepared by blending chitosan with bamboo charcoal and forming composite beads. The composites were used as reactive dye adsorbents. Adsorption equilibrium experiments were carried out as a function of contact time, bamboo charcoal concentration, pH value, and adsorbent dosage level. The equilibrium time of dye adsorption was found to be 8 h. Composite adsorbent had the highest adsorption efficiency when the weight ratio was 50/50. The maximum dye removal took place at the initial pH value of 4.0. The optimum adsorbent dosage for dye removal was 6.0 g. Under above optimal conditions the maximum dye removal was 98.4%. The adsorption isotherm of chitosan and chitosan/bamboo charcoal composite beads agreed well with the Langmuir model. The maximum adsorption capacity was 3.47 mg/g for chitosan bead and 4.32 mg/g for chitosan/bamboo charcoal composite bead, respectively. SEM micrographs confirm that after adsorption the pores were packed with Reactive Red 152.
Sangsawang B.,Srinakharinwirot University |
Sangsawang N.,Srinakharinwirot University
International Urogynecology Journal and Pelvic Floor Dysfunction | Year: 2013
Introduction and hypothesis: Stress urinary incontinence (SUI) is the most common type of urinary incontinence (UI) in pregnant women and is known to have detrimental effects on the quality of life in approximately 54.3 %. Pregnancy is the main risk factor for the development of SUI. This review provides details of the pathophysiology leading to SUI in pregnant women and SUI prevalence and treatment during pregnancy. Methods: We conducted a PubMed search for English-language and human-study articles registered from January 1990 to September 2012. This search was performed for articles dealing with prevalence and treatment of SUI during pregnancy. In the intervention studies, we included studies that used a randomized controlled trial (RCT) design or studies comparing a treatment intervention to no treatment. Results: A total of 534 articles were identified; 174 full-text articles were reviewed, and 28 of them met eligibility criteria and are reported on here. The mean prevalence of SUI during pregnancy was 41 % (18.6-60 %) and increased with gestational age. The increasing pressure of the growing uterus and fetal weight on pelvic-floor muscles (PFM) throughout pregnancy, together with pregnancy-related hormonal changes, may lead to reduced PFM strength as well as their supportive and sphincteric function. These cause mobility of the bladder neck and urethra, leading to urethral sphincter incompetence. Pelvic floor muscle exercise (PFME) is a safe and effective treatment for SUI during pregnancy, without significant adverse effects. Conclusions: Understanding these issues can be useful for health-care professionals when informing and counseling pregnant women to help prevent SUI during pregnancy and the postpartum period. © 2013 The Author(s).
Neruntarat C.,Srinakharinwirot University
Laryngoscope | Year: 2011
Objective: To study long-term results in patients undergoing uvulopalatal flap (UPF) for obstructive sleep apnea (OSA). Design: Prospective, clinical trial at tertiary referral center. Material and Methods: A study was undertaken on 83 OSA patients with palatal obstruction based on radiography and physical findings. UPF was conducted to increase the airway space and data were analyzed. Results: Patients had a mean age of 36.5 ± 12.3 years and a mean body mass index (BMI) of 29.4 ± 4.3 kg/m2. The mean follow-up was 54.2 ± 8.9 months, with a range of 48 to 62 months. The mean baseline apnea-hypopnea index (AHI), short-term AHI, and long-term AHI were 45.6 ± 10.3, 13.4 ± 5.2, and 19.4 ± 5.1, respectively. The mean baseline lowest oxygen saturation (LSAT), short-term LSAT, and long-term LSAT were 82.6 ± 5.4%, 89.2 ± 4.8%, and 88.1 ± 3.2%, respectively. Forty-three patients (51.8%) had long-term success, and 15 patients(25.8%) had an increase in the AHI over the follow-up period such that they were no longer considered success by traditional AHI criteria. Serious complications were not encountered. Conclusions: UPF is a safe and effective procedure that results in long-term success for OSA. However, a regular follow-up is important because some patients will relapse in the long term. © 2010 The American Laryngological, Rhinological, and Otological Society, Inc.
Hongratanaworakit T.,Srinakharinwirot University
Natural Product Communications | Year: 2011
Although blended essential oils are increasingly being used for the improvement of the quality of life and for the relief of various symptoms in patients, the scientific evaluation of the aroma-therapeutic effects of blended essential oils in humans is rather scarce. In this study, we hypothesized that applying blended essential oil would provide a synergistic effect that would have a chance for success in treating depression or anxiety. Therefore, the main objective of this study was to investigate the effects of the blended essential oil on autonomic parameters and on emotional responses in humans following transdermal absorption. The blended essential oil consisted of lavender and bergamot oils. Human autonomic parameters, i.e. blood pressure, pulse rate, breathing rate, and skin temperature, were recorded as indicators of the arousal level of the autonomic nervous system. In addition, subjects had to rate their emotional condition in terms of relaxation, vigor, calmness, attentiveness, mood, and alertness in order to assess subjective behavioral arousal. Forty healthy volunteers participated in the experiments. Blended essential oil was applied topically to the skin of the abdomen of each subject. Compared with placebo, blended essential oil caused significant decreases of pulse rate, and systolic and diastolic blood pressure, which indicated a decrease of autonomic arousal. At the emotional level, subjects in the blended essential oil group rated themselves as 'more calm' and 'more relaxed' than subjects in the control group. This finding suggests a decrease of subjective behavioral arousal. In conclusion, our investigation demonstrates the relaxing effect of a mixture of lavender and bergamot oils. This synergistic blend provides evidence for its use in medicine for treating depression or anxiety in humans.
Naphon P.,Srinakharinwirot University
International Journal of Heat and Mass Transfer | Year: 2016
The heat transfer and flow characteristics of the nanofluids in the horizontal spirally coiled tubes are investigated. The spirally coiled tubes are fabricated by bending a 8.50 mm inner diameter straight copper tube into a spiral-coil of five turns. The test section with three different curvature ratios of 0.035, 0.043, 0.06 are tested. Effects of curvature, nanofluids concentration and hot water temperature on the nanofluids heat transfer characteristics and pressure drop are considered. The results showed that the Nusselt number is about 21.29%, 29.02%, 34.07% for (0.01%, 0.025%, 0.05% by volume concentration, respectively) higher than the Nusselt number obtained for water as working fluid. However, the friction factor of nanofluids as working fluid increase slightly compared that of water as working fluid. Two correlations for predicted the Nusselt number and friction factor in the spirally coiled tube under constant wall temperature are proposed. © 2015 Elsevier Ltd.All rights reserved.
Sangsawang B.,Srinakharinwirot University
European Journal of Obstetrics Gynecology and Reproductive Biology | Year: 2014
The most common type of urinary incontinence (UI) in pregnant women is stress urinary incontinence (SUI). The number of pregnant women with SUI was variable, the prevalence ranged from 18.6% to 75% and increased with gestational age. It can affect the quality of life (QoL) of approximately 54.3% of all pregnant women in four domains including physical activity, travel, social relationships and emotional health. Pregnancy is one of the main risk factors for the development of SUI in young women. Physiological changes during pregnancy, such as increasing pressure of the growing uterus and fetal weight on the pelvic floor muscle (PFM) throughout pregnancy, together with pregnancy-related hormonal changes such as increased progesterone, decreased relaxin, and decreased collagen levels, may lead to reduced strength and supportive and sphincteric function of the PFM. Pregnancy may associate with the reduction of the PFM strength which can develop the SUI. However, the exact causes of pregnancy-related SUI remain unclear. Multiple factors have been found to be associated with the development of SUI during pregnancy. In genetic risk factors, aging is an important role in SUI development. The other risk factors such as obesity, smoking, constipation, pre-pregnancy SUI, gestational diabetes mellitus (GDM), and pelvic floor muscle exercise (PFME) that utilized preventive strategies can reduce SUI in pregnant women. The purpose of this review is to identify the risk factors for the development of SUI in pregnant women. These understanding can be useful for health professions to inform and counsel the pregnant women to prevent and reduce the risk factors that contribute to the development of SUI during pregnancy and postpartum period. © 2014 Elsevier Ireland Ltd.
Phisut N.,Srinakharinwirot University
International Food Research Journal | Year: 2012
Spray drying is a process widely used to produce fruit juice powders. In powders, it results with the good quality, low water activity, easier transport and storage. The physicochemical properties of powders produced by spray drying depend on the variables of process and/or operating parameters. In the present review, the principle of spray drying was described. In addition, some factors such as inlet temperature, air dry flow rate, atomizer speed, feed flow rate, types of carrier agent and their concentration were reviewed.