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Bangkok, Thailand

Srinakharinwirot University is a public university located in Bangkok, Thailand. The university was founded in 1949. It was named by King Bhumibol Adulyadej after his mother and is the leading Thai university in the field of education and fine arts. It is the first institution of higher education in Thailand to concentrate solely on teacher training. Built upon the basis of Advanced Teacher’s College and Educational College, Srinakharinwirot University has firmly established educational basis within democratic, Thai society. Six decades following the basis were well carried through principles and educational theories. Developments include changes in university management, from a practitioner’s college to a multi-science university or comprehensive university. For three decades, the multi-science university has aimed at applying multiple science to empower intellectual society by putting efforts in research and academic excellence. Srinakharinwirote University currently has two campus:Prasarnmit Campus, BangkokOngkharak Campus, Ongkharak district, Nakhon Nayok Province Wikipedia.

Chitanuwat A.,Srinakharinwirot University
Journal of oral science | Year: 2013

High mobility group box 1 (HMGB1) was originally defined as a nuclear protein. However, later studies showed that HMGB1 was released from damaged cells into the extracellular milieu and functioned as a danger signaling molecule. HMGB1 has also been shown to exert proliferative and chemoattractant effects on many cell types. In this study, we investigated the in vitro effect of human recombinant HMGB1 on the proliferation and migration of human gingival fibroblasts (HGF) and human periodontal ligament fibroblasts (HPDLF). For the proliferation assay, HGF and HPDLF were cultured in the presence of 5, 10, and 50 ng/mL HMGB1. After a period of 6 days, cell proliferation was determined by MTT assay. The migration assay was performed by culturing the two cell types in Transwells with HMGB1 in the lower chamber as a chemoattractant. Cell migration during 16 h was determined by crystal violet staining of the cells that migrated across the membrane. The results showed that HMGB1, at 50 ng/mL, was able to significantly induce proliferation of HGF by up to 171.4 ± 17.1%. No such proliferation induction was seen for HPDLF. In the migration assay, however, 100 ng/mL HMGB1 induced migration of both cell types. The counts of cells that migrated across the membrane, as compared with the control, were increased to 273 ± 24.1% and 410.3 ± 158% for HGF and HPDLF, respectively. Since proliferation and migration are basic abilities of cells required for proper tissue repair, these data suggest that HMGB1 plays an important role in these functions of periodontal cells. Source

Naphon P.,Srinakharinwirot University
International Journal of Heat and Mass Transfer | Year: 2016

The heat transfer and flow characteristics of the nanofluids in the horizontal spirally coiled tubes are investigated. The spirally coiled tubes are fabricated by bending a 8.50 mm inner diameter straight copper tube into a spiral-coil of five turns. The test section with three different curvature ratios of 0.035, 0.043, 0.06 are tested. Effects of curvature, nanofluids concentration and hot water temperature on the nanofluids heat transfer characteristics and pressure drop are considered. The results showed that the Nusselt number is about 21.29%, 29.02%, 34.07% for (0.01%, 0.025%, 0.05% by volume concentration, respectively) higher than the Nusselt number obtained for water as working fluid. However, the friction factor of nanofluids as working fluid increase slightly compared that of water as working fluid. Two correlations for predicted the Nusselt number and friction factor in the spirally coiled tube under constant wall temperature are proposed. © 2015 Elsevier Ltd.All rights reserved. Source

Neruntarat C.,Srinakharinwirot University
European Archives of Oto-Rhino-Laryngology | Year: 2011

Successful results of palatal implants in the treatment of obstructive sleep apnea (OSA) have been reported in the short term; however, there are limited data in the long-term results. The aim of this study was to evaluate the long-term results and to determine factors that predicted the responders in patients undergoing palatal implants in the treatment of OSA. A study was undertaken on 92 OSA patients. Palatal implants were conducted to stiffen the soft palate and data were analyzed. Patients tolerated the procedure well. They were examined between 26 and 32 months after the operation (mean 28.9 ± 4.8). Age range was 25-65 years (38.4 ± 10.5) and BMI was 27.3 ± 2.4 kg/m. The mean preoperative ESS score was 12.3 ± 2.6 and long-term ESS was 7.9 ± 1.8 (p < 0.001). The mean VAS for snoring in the baseline was 8.2 ± 1.2 and long-term VAS was 3.8 ± 2.3 (p < 0.001). The mean preoperative LSAT and long-term LSAT were 87.4 ± 6.7 and 89.2 ± 4.8%, respectively (p < 0.01). The mean AHI decreased from 21.7 ± 6.8 to 10.8 ± 4.8 (p < 0.001). Forty-eight (52.2%) patients had long-term surgical response. Responders had significantly lower preoperative BMI, AHI, and MMP level than non-responders. Implant extrusion occurred in seven patients (7.6%) and palatal abscess in one patient (1.1%). Bleeding and airway obstruction were not encountered. Palatal implants in carefully selected patients suffering from mild OSA, give fairly good long-term results and have a low complication rate. © 2011 Springer-Verlag. Source

Neruntarat C.,Srinakharinwirot University
Laryngoscope | Year: 2011

Objective: To study long-term results in patients undergoing uvulopalatal flap (UPF) for obstructive sleep apnea (OSA). Design: Prospective, clinical trial at tertiary referral center. Material and Methods: A study was undertaken on 83 OSA patients with palatal obstruction based on radiography and physical findings. UPF was conducted to increase the airway space and data were analyzed. Results: Patients had a mean age of 36.5 ± 12.3 years and a mean body mass index (BMI) of 29.4 ± 4.3 kg/m2. The mean follow-up was 54.2 ± 8.9 months, with a range of 48 to 62 months. The mean baseline apnea-hypopnea index (AHI), short-term AHI, and long-term AHI were 45.6 ± 10.3, 13.4 ± 5.2, and 19.4 ± 5.1, respectively. The mean baseline lowest oxygen saturation (LSAT), short-term LSAT, and long-term LSAT were 82.6 ± 5.4%, 89.2 ± 4.8%, and 88.1 ± 3.2%, respectively. Forty-three patients (51.8%) had long-term success, and 15 patients(25.8%) had an increase in the AHI over the follow-up period such that they were no longer considered success by traditional AHI criteria. Serious complications were not encountered. Conclusions: UPF is a safe and effective procedure that results in long-term success for OSA. However, a regular follow-up is important because some patients will relapse in the long term. © 2010 The American Laryngological, Rhinological, and Otological Society, Inc. Source

Nitayaphat W.,Srinakharinwirot University
Chiang Mai Journal of Science | Year: 2014

Chitosan/bamboo charcoal composites were prepared by blending chitosan with bamboo charcoal and forming composite beads. The composites were used as reactive dye adsorbents. Adsorption equilibrium experiments were carried out as a function of contact time, bamboo charcoal concentration, pH value, and adsorbent dosage level. The equilibrium time of dye adsorption was found to be 8 h. Composite adsorbent had the highest adsorption efficiency when the weight ratio was 50/50. The maximum dye removal took place at the initial pH value of 4.0. The optimum adsorbent dosage for dye removal was 6.0 g. Under above optimal conditions the maximum dye removal was 98.4%. The adsorption isotherm of chitosan and chitosan/bamboo charcoal composite beads agreed well with the Langmuir model. The maximum adsorption capacity was 3.47 mg/g for chitosan bead and 4.32 mg/g for chitosan/bamboo charcoal composite bead, respectively. SEM micrographs confirm that after adsorption the pores were packed with Reactive Red 152. Source

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