Srinagar, India
Srinagar, India
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Hussain A.,Srinagar | Aziz S.A.,Medical Oncology | Bhatt G.M.,Srinagar | Lone A.R.,Srinagar | And 3 more authors.
Journal of Obstetrics and Gynecology of India | Year: 2015

Aims: Gestational trophoblastic neoplasia (GTN) comprise a spectrum of interrelated conditions originating from the placenta. With sensitive assays for human chorionic gonadotropin (β-hCG) and current approaches to chemotherapy, most women with GTN can be cured with preservation of reproductive potential. The purpose of this analysis was to address the outcome of GTN in patients from a tertiary care center of India. Materials and Methods: We undertook a retrospective and prospective review of GTN cases treated at our center over a period of 7 years from 2008 to 2014. Patients of GTN were assigned to low-risk or high-risk categories as per the FIGO scoring system. The low-risk group was treated with combination of actinomycin-D and methotrexate and the high-risk group received the Etoposide, Methotrexate, Actinomycin-D/ Cyclophosphamide, Vincristine (EMA/CO) regimen. Salvage therapy was Etoposide, Paclitaxel /Paclitaxel, Cisplatin (EP/TP). Treatment was continued for three cycles after normalization of β-hCG level, after which the patients were followed up regularly. Results: In total, 41 GTN patients were treated at our institution during the above period; 17 were in the low-risk and 24 were in the high-risk category. The lung was the most common site of metastasis. All low-risk patients achieved complete remission. Among high-risk patients, one patient died while receiving first cycle chemotherapy, one patient relapsed, and 22 patients achieved complete remission. The single relapsed patient also achieved remission with second-line chemotherapy. Conclusion: Risk-stratified treatment of GTN was associated with acceptable toxicity and resulted in outcome that was comparable with international standards. The use of two-drug combination in low-risk patients is a better option especially in developing countries. © 2015 Federation of Obstetric & Gynecological Societies of India

Khan M.A.,Srinagar
Lakes and Reservoirs: Research and Management | Year: 2015

Hokersar wetland (altitude of 1584 masl), a shallow (0.5 m) floodplain waterfowl habitat in Kashmir, India, gained international importance in 2005 with its declaration as a Ramsar site. Although isolated in the western Himalayan mountains, it is being impacted by a silt-laden river (Doodhganga). Human activities, not the least of which is affected by the closeness of the wetland to suburban areas, have gradually altered its trophic state. Its alkaline- and calcium-rich waters contain many planktonic diatoms, green algae and cyanobacteria. Nitrate-nitrogen and total phosphorus concentrations are high (370-4750 and 101-968 μg L-1, respectively). A pronounced seasonal cycle in phytoplankton production (g C m-2 day-1) was evident in a minimum value of 0.38 (Jan-Feb, 2002) and a maximum value of 4.02 (July, 2002), closely paralleling the seasonal cycles of temperature and light. The photosynthetic efficiency of the wetland was highest (1.97%) during the summer. The annual phytoplankton production of this wetland ecosystem was 210 × 102 KJ m-2, suggestive of a meso-eutrophic status. © 2015 Wiley Publishing Asia Pty Ltd.

Wani I.A.,Srinagar | Bhat M.Y.,Srinagar | Banday F.A.,Srinagar | Khan I.A.,Srinagar | And 3 more authors.
Plant Archives | Year: 2012

Studies were carried out to find out association between different characters and magnitude of association of different characters in thirty three genotypes of pomegranate (Punica granatum L.). Data revealed that plant height, plant spread, number of fruit per tree, yield per tree and yield efficiency exhibited highly significant positive correlation. Among fruit characters, fruit length, fruit diameter, fruit weight, fruit volume, total aril weight, number of arils per fruit, rind thickness and rind weight recorded maximum positive correlation at phenotypic level. This study revealed that number of fruits per tree, yield per tree, fruit size; fruit weight and anthocyanin content form selection criteria for yield improvement in pomegranate. Therefore, direct emphasis need to be laid on the traits showing positive direct effects while selection for the number of fruits and fruit weight in pomegranate.

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