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Chandru K.,Sri Siddhartha Medical College
Indian Journal of Forensic Medicine and Toxicology | Year: 2010

Back ground and objective: With wide spread use of electricity at home and work place the amount of electrical related injuries are on the rise. The present study attempts to know distribution pattern of electrical injuries and Histo Pathological changes in skin with electrical contact mark and in internal organs. Methods: Study was conducted on deaths due to electrocution brought to Victoria hospital mortuary during the period of two years. Specimen of skin with contact mark and internal organs like heart, kidney was sent for Histo Pathological examination. Data will be collected from police inquest and photographic evidence from scene of occurrence. Result: Total number of 61 cases was studied in two-year period. High voltage electrocution constituted 54% of cases. Low voltage electrocution constituted 46%. High voltage electrocution mainly presented as flash burns, while low voltage electrocution presented with contact mark. Typical Histo Pathological changes were seen in skin and heart specimen sent for examination. Histo Pathological changes in kidney were nonspecific. Conclusion: Electric contact mark is diagnostic criteria for electrocution. Histo Pathological changes were used as supportive evidence in determining cause of death. Main reasons for electrocution deaths were found to be human negligence, faulty electrical equipments and connections and lack of protective measures. Source


Ajith S.,Sri Siddhartha Medical College
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2015

Eye is a mirror that reflects pathological changes occurring in many organs of the body. Chronic renal failure is irreversible and progressive process that result in End stage renal disease [ESRD] where patient depend on renal replacement for survival1. In this study we are looking for diabetic retinopathy in patients with ESRD of diabetic origin. To record the stage of retinopathy in end stage renal disease patients of diabetic origin and record the progress of retinopathy at the end of 6 months and 12 months in these patients. The study was done in Sri Siddartha Medical College, Tumkur from May 2014 to May 2015. This is a prospective non randomized study of 50 patients who were diagnosed end stage renal disease of diabetic etiology with or without hypertension. Majority of patients were in age group of 55-60 years accounting 60%, men 32% and women 28%. All patients were known to be diabetic for more than 5 years. Patients who were diabetic for about 11-15 years were the majority. All patients of NIDDM with ESRD had retinopathy. Source


Haniadka R.,Research and Development | Popouri S.,Sri Siddhartha Medical College | Palatty P.L.,Research and Development | Arora R.,Office of the Controller Research and Development Life science and International Collaboration | Baliga M.S.,Research and Development
Integrative Cancer Therapies | Year: 2012

Chemotherapy- and radiotherapy-induced nausea and vomiting are the most common, intractable and unpleasant side effects in patients undergoing treatment for cancer. 5-Hydroxytryptamine-3 (5-HT3) receptor antagonists plus dexamethasone have significantly improved the control of acute nausea and vomiting, but delayed nausea and vomiting remains a significant clinical problem. Combined neurokinin-1 receptor antagonists with 5-HT3 antagonists and steroids are observed to be better in the control of both acute and delayed emesis. However, the use of these antiemetics is observed to possess inherent side effects. The medicinal plants such as Scutellaria baicalensis, Korean red ginseng, American ginseng berry, Ganoderma lucidum, Zingiber officinale, grape seed extract, and the oil of Mentha spicata are reported to be effective in the treatment of nausea and vomiting mostly in preclinical studies. Of these, ginger has also been evaluated for its efficacy in humans and the results have been contradictory. The current review for the first time summarizes the results related to these properties. An attempt is also made to address the lacunae in these published studies and to emphasize aspects that need further investigations for these plants to be of use in clinics in the future. © The Author(s) 2012. Source


Belagavi A.C.,Ms Ramaiah Medical College And Hospitals | Shalini M.,Sri Siddhartha Medical College
Journal of Association of Physicians of India | Year: 2011

Objectives: to assess the utility of C-reactive protein (CrP) levels and adenosine deaminase (ADA) activity in the cerebrospinal fluid (CsF) as rapid screening tests to differentiate various types of meningitis in adults and to establish a cut off level for ADA. Methods: CsF samples were obtained from 50 patients who presented to the emergency room and out-patient of sri siddhartha medical Hospital, tumkur during the period between August 2006 and september 2008. Diagnosis of meningitis was based on the clinical presentation and CsF analysis. Results: Out of a total of 50 patients who were enrolled in the study, 24 were diagnosed as tubercular meningitis (tbm) based on the clinical features and CsF analysis. the mean Adenosine deaminase (ADA) activity was 14.14±7.44 U/l in the tbm group. the sensitivity and specificity was 73.9% and 92.6% respectively when a cut-off value of ADA of 10U/l was used, with an accuracy of 84%. CsF-C reactive protein (CrP) was significantly higher in pyogenic meningitis compared to non-pyogenic meningitis. the sensitivity and specificity of the test was 83.3% and 100% respectively with an accuracy of 98%. Conclusions: 2 rapid screening tests- CrP and ADA activity in the CsF can help in the differential diagnosis of pyogenic from non-pyogenic meningitis and tubercular from viral meningitis respectively. CrP being elevated in pyogenic meningitis and ADA activity noted to be higher in tbm. the levels of ADA and CrP were found to be low in viral meningitis. © JAPI. Source


Gangadhar S.B.,Sri Siddhartha Medical College | Gopal T.M.,Maidstone General Hospital | Sathyabhama,Maidstone General Hospital | Paramesh K.S.,Kingston Hospital
Indian Journal of Anaesthesia | Year: 2012

The number of day-care surgeries is increasing every day. The boundaries of day-care surgeries are being redefined on a continual basis. Multi-dimensional benefits to the patient, hospital and national economy are the driving forces behind the changing scenario on the horizon of day surgery. The literature search included Google, medlinx, pubmed and medline. We have attempted to look at the controversies in patient selection with comorbidities, preoperative assessment and an acceptable ASA grade of patients. An attempt is also made to look at suitable surgical procedures, a pathway of introducing procedures, which are still complex and specialist procedures in challenging environment. The techniques of general anaesthesia, central neuraxial blocks, regional nerve blocks with indwelling catheters and monitoring techniques are deliberated upon. Finally the most important post-operative issues of discharge criteria, including recovery after spinal anaesthetic, oral fluid intake, voiding and travel after day surgery, are considered. Source

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