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Tirupati, India

Sri Padmavati Mahila Visvavidyalayam is a women's university in Tirupati, Andhra Pradesh, India. It was established as a state university by the Andhra Pradesh legislature in 1983, named after the goddess Sri Padmavati, the consort of Lord Venkateswara. The university has approximately 3,000 students. Wikipedia.


Pounambal M.,Vellore Institute of Technology | Krishna P.V.,Sri Padmavati University
International Journal of Communication Systems | Year: 2016

In wireless mesh networks, the availability of spectrum should be utilized efficiently because the exchanging of traffic rate of multimedia applications is increasing day to day. The traffic of multimedia content may degrade the network performance in terms of high packet loss and throughput degradation because of asynchronous behavior between the sender and the receiver. The proposed Efficient Channel Reservation and Assignment (EchRA) results in successful originating and handing off of multimedia call transmissions using the four dimensional Markov chain process. The EChRA algorithm, proposed in this paper, achieves the maximum throughput performance considering the parameters of blocking probability, dropping probability, and synchronized dwell time between the source and destination. The quality of service is guaranteed by sharing the available slots and by using efficient queuing model to service the incoming and handoff calls, and henceforth, the successful completion of handoff calls rate is increased. Copyright © 2015 John Wiley & Sons, Ltd. Source


Asuntha G.,S P W Polytechnic | Prasannaraju Y.,UCSI University | Prasad K.V.S.R.G.,Sri Padmavati University
Tropical Journal of Pharmaceutical Research | Year: 2010

Purpose: Indigofera tinctoria Linn. of the Fabaceae family is claimed to be useful in the treatment of a variety of epileptic disorders in Indian traditional system of medicine. The present study was designed to verify this claim. Methods: Status epilepticus was induced in male albino rats of Wistar strain by administration of pilocarpine (30 mg/kg, i.p.) 24 h after injection of lithium chloride (3 mEq/kg, i.p.). Different doses of the ethanol extract of Indigofera tinctoria were administered orally 1 h before the injection of pilocarpine. The severity of status epilepticus was observed and recorded every 15 min for 90 min and thereafter every 30 min for another 90 min, using Racine scoring system. In-vivo lipid peroxidation of rat brain tissue was measured in terms of the thiobarbiturate-reactive substances (TBARS). Both in-vitro free radical nitric oxide (NO) and 2-diphenyl-2-picryl hydrazyl (DPPH) scavenging activities of the extract were also determined. Results: The severity of status epilepticus was significantly (p < 0.01) reduced following oral administration of the extract at 500 and 1000 mg/kg doses. No test animal group exhibited stage 4 seizure. The extract also exhibited both in-vivo and in-vitro antioxidant activities. Conclusion: The ethanol extract of Indigofera tinctoria was found to be useful in controlling lithium/pilocarpine-induced status epilepticus in albino rats. © Pharmacotherapy Group. Source


Soumya V.,Sri Padmavati University | Muzib Y.I.,Sri Padmavati University
Indian Journal of Pharmacology | Year: 2016

Objective: To evaluate the potential effect of bamboo seed oil in decreasing the major metabolic symptoms associated with letrozole-induced polycystic ovarian disease using female rat model. Materials and Methods: A new method of microwave-assisted extraction was developed. Female rats were grouped into four with six animals each. All rats were daily administered with letrozole (1 mg/kg b.wt.) for 21 days except control, and during this period, changes in estrous cycle were observed. After letrozole treatment, Group 2 was considered negative control, Groups 3 and 4 were treated orally with bamboo oil, 0.5 ml/kg b.wt. and 1 ml/kg b.wt., respectively, for 3 weeks (five consecutive estrus cycles). Various parameters such as estrus cycle, blood sugar level, lipid profile, and weights of reproductive system were determined. The characteristics of cystic ovaries were evaluated by histopathological studies. Results: The isolated bamboo oil restored estrus cyclicity showed hypoglycemic and hypolipidemic effects. 1 ml/kg b.wt. of bamboo oil showed a marked glucose reduction from 254.04 ± 2.08 to 92.6 ± 1.63, and levels of total cholesterol, very low-density lipoprotein, triglyceride were reduced from 186.45 ± 2.28, 30.07 ± 2.36, 100.36 ± 2.35 to 152.14 ± 2.63, 25.94 ± 1.66, 93.32 ± 1.09, respectively. Histopathological results showed the presence of ovulation and recovery from cystic ovaries. Conclusion: A novel and promising drug was isolated in the treatment and maintenance of various metabolic symptoms associated with polycystic ovary disease. © 2016 Indian Journal of Pharmacology Published by Wolters Kluwer - Medknow. Source


Asha S.,Sri Padmavati University | Vidyavathi M.,Sri Padmavati University
Applied Biochemistry and Biotechnology | Year: 2010

Drug metabolism studies are essential and necessary during the evaluation of drugs. This review discusses the in vitro human liver models to estimate the drug metabolic fates in vivo. Different approaches are provided and emphasis is placed on the potential of human liver microsomes for drug metabolism and inhibition studies. The methodology for these studies using human liver microsomes, applications of human liver microsomes, and the drugs studied by human liver microsomes are listed. Human liver microsomes represent a critical experimental model for the evaluation of drug metabolites with a high probability of clinical success. © 2009 Humana Press. Source


Akondi K.B.,Sri Padmavati University | Lakshmi V.V.,Sri Padmavati University
OMICS A Journal of Integrative Biology | Year: 2013

Microorganisms constitute two out of the three domains of life on earth. They exhibit vast biodiversity and metabolic versatility. This enables the microorganisms to inhabit and thrive in even the most extreme environmental conditions, making them all pervading. The magnitude of biodiversity observed among microorganisms substantially supersedes that exhibited by the eukaryotes. These characteristics make the microbial world a very lucrative and inexhaustible resource for prospecting novel bioactive molecules. Despite their vast potential, over 99% of the microbial world still remains to be explored. The primary reason for this is that the culture-dependent methods used in the laboratories are grossly insufficient, as they support the growth of under 1% of the microorganisms found in nature. This limitation necessitated the development of techniques to circumvent culture dependency and gain access to the outstanding majority of the microorganisms. The development of culture-independent techniques has essentially reshaped the study of microbial diversity and community dynamics. Application of genomic and metagenomic approaches is contributing substantially towards characterization of the real microbial diversity. The amenability of these techniques to high throughput has opened the doors to explore the vast number of "uncultivable" microbial forms in substantially lesser time. The present article provides an update on the recent technological advances and emerging trends in exploring microbial community. © Copyright 2013, Mary Ann Liebert, Inc. 2013. Source

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