Sri Manakula Vinayagar Medical College & Hospital

Puducherry, India

Sri Manakula Vinayagar Medical College & Hospital

Puducherry, India
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PubMed | Sri Lakshminarayana Institute of Medical science and Sri Manakula Vinayagar Medical College & Hospital
Type: Journal Article | Journal: Sultan Qaboos University medical journal | Year: 2016

The infrahyoid muscles are involved in vocalisation and swallowing; among these, the sternothyroid muscle is derived from the common primitive sheet. The improper differentiation of this muscle may therefore result in morphological variations. We report an unusual variation found during the dissection of a 65-year-old male cadaver at the Sri Manakula Vinayagar Medical College, Madagadipet, Pondicherry, India, in 2015. An anomalous belly of the right sternothyroid muscle was observed between the internal jugular (IJ) vein and the internal carotid artery with an additional insertion into the tympanic plate and petrous part of the temporal bone and the presence of a


Mangaiarkkarasi A.,Sri Manakula Vinayagar Medical College Hospital | Meher Ali R.,Sri Manakula Vinayagar Medical College Hospital | Gopal R.,Sri Manakula Vinayagar Medical College Hospital
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2013

Escherichia coli is one of the common cause of both nosocomial and community acquired infections in humans. Occurrence of multiresistant strains necessitates periodic monitoring of its susceptibility pattern. This retrospective study was done in the Department of Pharmacology and Microbiology at Sri Manakula Vinayagar Medical College Hospital, Pondicherry. During the period from January 2012 to August 2012, a total of 5381 specimens (Urine, Blood, Pus, Swab, Cerebrospinal fluid etc.) were processed for culture and sensitivity according to CLSI recommendations. Sensitivity pattern was shown using descriptive stastistics. Gram negative bacteria accounted for about 62% of the isolates. The main species were E.coli 483(52.6%), Klebsiella sp.196 (21.3%), Pseudomonas sp.167 (18%), Proteus sp.38(4%), Salmonellasp.17(2%), Citrobacter 8 (0.8%), Moraxella 3(0.3%), Vibrio 2(0.2%), and H.influenza, Acinectobacter and Enterobacter 1(0.1%). E.coli showed high level of susceptibility to Imipenem (99.7%), Piperacillin+Tazobactum (97%), Meropenam(95%), Nitrofurantoin(92%) and Amikacin(84%). Very high rates of resistance was seen with Ampicillin(88%), Nalidixic acid and(86%), Amoxycillin + clavulanic acid(84%) and Cotrimoxazole(74%). Periodicmonitoring of antimicrobial susceptibility both in the community and hospital settings isrecommended to identify the sensitivity and resistant patterns of E.coli.


Poomalar G.K.,Sri Manakula Vinayagar Medical College Hospital | Rekha R.,Sri Manakula Vinayagar Medical College Hospital
Journal of Clinical and Diagnostic Research | Year: 2014

Scrub typhus is endemic and re-emerging in eastern and southern Asia. Illness varies from mild and self-limiting to fatal. Only few studies were published about its effect in maternal and neonatal outcome. A retrospective analysis was done in six prenatal and two postnatal women with scrub typhus. Details about clinical presentation, investigations, treatment given, response to treatment and pregnancy outcome were collected. The common symptoms were fever with chills, vomiting, myalgia, headache and abdominal pain. Typical features of eschar and lymphadenopathy were noted in only two cases. Two patients presented with jaundice and altered liver function test. Two patients presented with breathlessness. One patient developed oligohydramnios. Two postnatal women developed scrub typhus following blood transfusion for postpartum haemorrhage. Because of its high prevalence, scrub typhus should be included in fever investigations in endemic areas, even in the absence of eschar. Early diagnosis of cases will help in less severe organ damage and easy recovery with antibiotics. Few evidences state that scrub typhus can spread through blood transfusion. Correlation between blood transfusion and scrub typhus has to be further evaluated. © 2014, Journal of Clinical and Diagnostic Research. All rights reserved.


Mangaiarkkarasi A.,Sri Manakula Vinayagar Medical college Hospital | Ivan E.A.,Sri Manakula Vinayagar Medical college Hospital | Gopal R.,Sri Manakula Vinayagar Medical college Hospital
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2013

Antimicrobial resistance is a global emerging problem in the community and in hospitals. The present study was undertaken to evaluate the antimicrobial susceptibility patterns of common gram negative organisms isolated from hospital specimens. Antimicrobial susceptibility data of organisms isolsted from different samples were analyzed in the department of pharmacology and Microbiology at Sri Manakula Vinayagar Medical College Hospital, Pondicherry over eight months period. Out of 5381 specimens, the culture positive specimens were pus 60%, Cerebrospinal fluid 31.5%, urine 26%, synovial fluid 25%, swabs 25%, ascitic fluid 23.2%, sputum 18.6%, stool 18%, pleural fluid 15.5%, blood 13%, & others 27.7%. Gram negative bacteria accounted for 62% of isolates. The main species were E.coli (52.6%), Klebsiella spp. (21.3%), Pseudomonas spp. (18%) and Proteus spp. (4%). Maximum susceptibility of E. coli was observed with Imepenam (99.7%), Pipercillin+ Tazobactam, (97% each) followed by Meropenem (95%), Nitrofurantoin (92%) and Amikacin(84%); of Klebsiella spp. and Proteus spp. to Meropenem, Pipercillin + Tazobactam, (100% each) and of Pseudomonas spp. to Imepenam (82.6%), Aztreonam, Ciprofloxacin (80%each) followed by Tobramycin (77.7%). High level of resistance was observed with Amoxycillin + Clavulanicacid (80-90%), Ampicillin (65-95%), Co-trimoxazole (70-90%), Ciprofloxacin (60-90%). Based on the above study Imepenam, Pipercillin+ Tazobactam, Meropenem were the effective antimicrobials for E. coli, Proteus spp. and Klebsiella spp. and Imepenam, Aztreonam, Ciprofloxacin and Tobramycin for Pseudomonas spp.


Mangaiarkkarasi A.,Sri Manakula Vinayagar Medical College Hospital | Meher Ali R.,Sri Manakula Vinayagar Medical College Hospital | Gopal R.,Sri Manakula Vinayagar Medical College Hospital
International Journal of Pharma and Bio Sciences | Year: 2013

The present study was undertaken with an aim to assess the existing antimicrobial susceptibility pattern of Pseudomonas aeruginosa from diverse clinical samples of our hospital. A total of 5381 biological specimens were processed for culture and sensitivity between January to August 201. Pseudomonas aeruginosa accounted for 15% of the gram negative organisms, predominantly isolated from pus (64%) and urine (16.6%) samples. Maximum susceptibility was observed to meropenam (100%), imepenam (82.6%), aztreonam(80%), followed by ciprofloxacin, tobramycin (77.7%), ceftazidime (57.5%) and ceftriaxone (57.1%). A high level of resistance was observed to ticarcillin (69.2%) and amikacin (50%). Based on the above study, the use of meropenam, imepenam, aztreonam, ciprofloxacin and tobramycin appears to be rationale and warrant careful consideration by clinicians to monitor and optimize the use of antimicrobials to reduce occurrence and spread of resistant pathogen.


Poomalar G.K.,Sri Manakula Vinayagar Medical College Hospital | Arounassalame B.,Sri Manakula Vinayagar Medical College Hospital
Journal of Clinical and Diagnostic Research | Year: 2013

Introduction: The overall health and well-being of middle-aged women has become a major public health concern around the world. More than 80% of the women experience physical or psychological symptoms in the years when they approach menopause, with various distresses and disturbances in their lives, leading to a decrease in the quality of life. The aim of our study was to assess the quality of life and the impact of hormonal changes in perimenopausal and postmenopausal women and to correlate the prevalence of the symptoms with their duration since menopause. Material and Methods: A cross- sectional study was done at Sri Manakula Vinayagar Medical College and Hospital, Puducherry, from January 2012 to April 2012. Five hundred women who were in the age group of 40-65 years, who came from rural areas to our hospital, were included in the study. The women who were receiving hormonal treatment and those who refused to participate in the study were excluded. The data such as the socio-demographic information and the menstruation status, which were based on the reported length of time since the last menstrual period and the experience of the symptoms, as were tested in the Menopause Specific Quality of Life (MENQOL) questionnaire, were collected from each patient. The women who were included in the study were divided into three groups as the menopause transition, early postmenopausal and the late postmenopausal groups. All the data which were gathered were analyzed by using SAS 9.2. The Chi square test and the relative risk and the confidence interval calculations were applied to compare the frequencies of the symptoms among the women with different menopausal statuses. A p-value of less than 0.05 was considered to be statistically significant. Results: Mean menopausal age in the study group was 45 years. The most common symptom within study subjects were low back ache (79%) and muscle-joint pain (77.2%). The least frequent symptoms were increase in facial hair (15%) and feeling of dryness during intimacy (10.8%). Scores of vasomotor domain were significantly more in menopause transition group. Scores of physical domain were significantly more in late postmenopausal group. Conclusion: The menopause related symptoms had a negative effect on the quality of life of the perimenopausal and the postmenopausal women. Such regional studies can help in creating awareness and in educating women on the early identification of the common menopausal symptoms.


PubMed | Sri Manakula Vinayagar Medical College & Hospital
Type: Journal Article | Journal: Indian journal of physiology and pharmacology | Year: 2013

Prehypertension (PHT) leads to hypertension (HT) and cardiovascular (CVD) disease risk. Identification of CVD risk factors in PHT will reduce the burden of HT and CVD in the population. Three hundred staffs of a medical college were screened for prehypertension (PHT). Sixty five PHT and 91 normotensives (NT) were enrolled. Anthropometric measurements and fasting blood glucose and lipid variables were measured. Prevalence of PHT was 22% (males 71%; females 29%). Hip circumference, waist circumference (WC), body mass index (BMI), fasting blood glucose (FBS) and atherogenic lipid indices triglycerides (TG), VLDL cholesterol, TG/HDL and LDL/HDL were increased in PHT. PHT showed significant positive association with BMI, WC, FBS, TG and TG/HDL. Regression analysis revealed BMI, TG and TG/HDL as the independent CVD risk factors in PHT. PHT is predominant in males and BMI, TG are the independent CVD risk factors in Puducherry.


PubMed | Sri Manakula Vinayagar Medical College Hospital
Type: Journal Article | Journal: World journal of diabetes | Year: 2015

Gestational diabetes mellitus (GDM) is on the rise globally. In view of the increasing prevalence of GDM and fetal and neonatal complications associated with it, there is a splurge of research in this field and management of GDM is undergoing a sea change. Trends are changing in prevention, screening, diagnosis, treatment and future follow up. There is emerging evidence regarding use of moderate exercise, probiotics and vitamin D in the prevention of GDM. Regarding treatment, newer insulin analogs like aspart, lispro and detemir are associated with better glycemic control than older insulins. Continuous glucose monitoring systems and continuous subcutaneous insulin systems may play a role in those who require higher doses of insulin for sugar control. Evidence exists that favors metformin as a safer alternative to insulin in view of good glycemic control and better perinatal outcomes. As the risk of developing GDM in subsequent pregnancies and also the risk of overt diabetes in later life is high, regular assessment of these women is required in future. Lifestyle interventions or metformin should be offered to women with a history of GDM who develop pre-diabetes. Further studies are required in the field of prevention of GDM for optimizing obstetric outcome.


PubMed | Sri Manakula Vinayagar Medical College Hospital
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2015

Scrub typhus is endemic and re-emerging in eastern and southern Asia. Illness varies from mild and self-limiting to fatal. Only few studies were published about its effect in maternal and neonatal outcome. A retrospective analysis was done in six prenatal and two postnatal women with scrub typhus. Details about clinical presentation, investigations, treatment given, response to treatment and pregnancy outcome were collected. The common symptoms were fever with chills, vomiting, myalgia, headache and abdominal pain. Typical features of eschar and lymphadenopathy were noted in only two cases. Two patients presented with jaundice and altered liver function test. Two patients presented with breathlessness. One patient developed oligohydramnios. Two postnatal women developed scrub typhus following blood transfusion for postpartum haemorrhage. Because of its high prevalence, scrub typhus should be included in fever investigations in endemic areas, even in the absence of eschar. Early diagnosis of cases will help in less severe organ damage and easy recovery with antibiotics. Few evidences state that scrub typhus can spread through blood transfusion. Correlation between blood transfusion and scrub typhus has to be further evaluated.


PubMed | Sri Manakula Vinayagar Medical College Hospital
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2013

The overall health and well-being of middle-aged women has become a major public health concern around the world. More than 80% of the women experience physical or psychological symptoms in the years when they approach menopause, with various distresses and disturbances in their lives, leading to a decrease in the quality of life. The aim of our study was to assess the quality of life and the impact of hormonal changes in perimenopausal and postmenopausal women and to correlate the prevalence of the symptoms with their duration since menopause.A cross- sectional study was done at Sri Manakula Vinayagar Medical College and Hospital, Puducherry, from January 2012 to April 2012. Five hundred women who were in the age group of 40-65 years, who came from rural areas to our hospital, were included in the study. The women who were receiving hormonal treatment and those who refused to participate in the study were excluded. The data such as the socio-demographic information and the menstruation status, which were based on the reported length of time since the last menstrual period and the experience of the symptoms, as were tested in the Menopause Specific Quality of Life (MENQOL) questionnaire, were collected from each patient. The women who were included in the study were divided into three groups as the menopause transition, early postmenopausal and the late postmenopausal groups. All the data which were gathered were analyzed by using SAS 9.2. The Chi square test and the relative risk and the confidence interval calculations were applied to compare the frequencies of the symptoms among the women with different menopausal statuses. A p-value of less than 0.05 was considered to be statistically significant.Mean menopausal age in the study group was 45 years. The most common symptom within study subjects were low back ache (79%) and muscle-joint pain (77.2%). The least frequent symptoms were increase in facial hair (15%) and feeling of dryness during intimacy (10.8%). Scores of vasomotor domain were significantly more in menopause transition group. Scores of physical domain were significantly more in late postmenopausal group.The menopause related symptoms had a negative effect on the quality of life of the perimenopausal and the postmenopausal women. Such regional studies can help in creating awareness and in educating women on the early identification of the common menopausal symptoms.

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