Entity

Time filter

Source Type


Amarnath S.,Sri Lakshminarayana Institute of Medical SciencesPuducherry | Sharma A.,Sri Lakshminarayana Institute of Medical SciencesPuducherry | Rathna Kumar K.,Sri Lakshminarayana Institute of Medical SciencesPuducherry | Basalingappa S.,Sri Lakshminarayana Institute of Medical SciencesPuducherry | And 3 more authors.
International Journal of Pharmaceutical Sciences Review and Research | Year: 2014

Botulinum toxin is a neurotoxin produced by Clostridium botulinum which causes ‘Botulism’. Historically it has been associated with food intoxication and was used as a lethal weapon since ancient times. Identification of C. botulinum in the late 19th century by Van Ermengem led to clearer understanding of the action of this toxin and characterization of the microbe’s culture requirements. It has come a long way since and is now used therapeutically for a variety of clinical conditions like strabismus, blepharospasm, axillary hyperhidrosis etc. by employing a wide variety of available preparations (Botox®, Dysport® etc). This review highlights the clinical pharmacology of botulinum toxin along with the side effect profile and outlines the shift from using it as a lethal weapon to a promising therapeutic tool. © 2014 International Journal of Pharmaceutical Sciences Review and Research. Source

Discover hidden collaborations