Sri Kgs Arts College

Tamil Nadu, India

Sri Kgs Arts College

Tamil Nadu, India
Time filter
Source Type

Thangakrishnakumari S.,Sri Kgs Arts College | Nishanthini A.,Ethnopharmacology Unit | Muthukumarasamy S.,Sri Kgs Arts College | Mohan V.R.,Ethnopharmacology Unit
International Journal of Research in Ayurveda and Pharmacy | Year: 2012

The aim of the study was to investigate the hepatoprotective activity of ethanol extract of whole plant of Canscora perfoliata in CCl4 induced hepatotoxic rats. Administration of hepatotoxins (CCl4) showed significant elevation of serum SGOT, SGPT, ALP, bilirubin, conjugated, unconjugated bilirubin and lipid peroxidation. Treatment with Canscora perfoliata (150 and 300mg/kg) significantly reduced the above mentioned parameters. The plant extract also enhanced the antioxidant activity. The ethanol extract of Canscora perfoliata have significant effect on the CCl4 induced hepatotoxicity animal models.

Sankar U.,Sri KGS Arts College | Chithambrathanu T.,St Hindu College
Optik | Year: 2014

Triglycine sulphate crystals admixtured with picric acid (TGSPi) were grown by slow evaporation method in 30 days. Solubility of the grown sample is found to be increasing with increase in temperature. The grown TGSPi crystals are observed to be crystallizing in monoclinic structure. The mechanical strength of the crystal was estimated by Vickers hardness test. FTIR studies were performed to identify the presence of various functional groups present in the grown crystals. UV-vis spectral studies explain the transmission ability of the grown crystals. EDAX analysis confirms the elemental confirmation in TGSPi crystal. Kurtz-Perry powder technique was used to check the nonlinear optical activity of the sample. The grown crystals were also subjected to thermal analysis and dielectric studies. The obtained results are presented and discussed. © 2013 Elsevier GmbH.

PubMed | Sri Kgs Arts College, Manonmaniam Sundaranar University, Annamalai University and Vels University
Type: | Journal: International journal of biological macromolecules | Year: 2016

Fucoidan is one of the dominant sulfated polysaccharide which was extracted from the brown seaweed Turbinaria decurrens. In the behavioral study mice treated with fucoidan showed better response than the MPTP treated mice. Antioxidants and dopamine level has been increased in the fucoidan treated mice when compared to MPTP induced mice. In Immunohistochemistry, the increase of TH positive cells in the fucoidan treated group is correlated with the TH protein levels in substantia nigra and corpus striatum. The increase is greater than the content of dopamine and DOPAC, which may be explained that the dopaminergic terminals are more sensitive to MPTP toxicity and therefore are more severely damaged than the dopaminergic cell bodies. In immunoblotting TH and DAT was used, both the antibodies expression in MPTP was reduced and reversed in other groups. From the results it was conformed that the fucoidan has a neuroprotective effect without any side effects.

Vijayakumar N.,Sri Kgs Arts College | Subramanian E.,Manonmaniam Sundaranar University | Pathinettam Padiyan D.,Manonmaniam Sundaranar University
Synthetic Metals | Year: 2012

The present work is an investigation of AC impedance behaviors of polyaniline (PANI) and its poly(vinyl pyrrolidone) (PVP) blends. The materials were prepared by polymerization of aniline hydrochloride without/with PVP using FeCl 3 oxidant. PANI-PVP blends have greater AC conductivities than that of PANI in proportion to the amount of PVP incorporated. At lower frequencies (10 Hz - critical frequency f c) conductivity remains independent but at frequencies >f c, conductivity raises with frequency. In the entire range, however, the universal power law σ ac(ω) = Aω s holds good. In fresh condition PANI exhibits an increase in bulk resistance (R b) and frequency exponent s up to 373 K and blends up to 423 K beyond which they show a decrease. The trend in conduction could be explained by the operation of small polaron tunneling up to 373/423 K and afterwards correlated barrier hopping (CBH) conduction mechanisms. Studied PANI, PANI-PVP blend materials and a fresh but annealed (463 K) PANI all display only a decrease in R b and s values in the entire temperature range of study and hence they follow only CBH mechanism. The fresh samples, together with change of conduction mechanism with temperature also undergo submicron to nanoparticles conversion and changes in other physico-chemical properties. All these changes have the origin on elimination of occluded water from the fresh materials on heating. © 2011 Elsevier B.V. All rights reserved.

Rajasekar S.,Bharathidasan University | Jeyakumari S.,Sri KGS Arts College | Chinnathambi V.,Sri KGS Arts College | Sanjuan M.A.F.,Rey Juan Carlos University
Journal of Physics A: Mathematical and Theoretical | Year: 2010

We report our investigation into the role of depth and location of minima of a double-well potential on vibrational resonance in both underdamped and overdamped Duffing oscillators. The systems are driven by both low- and high-frequency periodic forces. We obtain theoretical expressions for the amplitude g of the high-frequency force at which resonances occur. The depth and location of the minima of the potential wells have a distinct effect on vibrational resonance in the underdamped and overdamped cases. In the underdamped system at least one resonance and at most two resonances occur and the number of resonances can be altered by varying the depth and location of the minima of the potential wells. We show that in the overdamped system there is always one and only one resonance, and the value of g at which resonance occurs is independent of the depth of the wells, but varies linearly with the locations of the minima of the wells. © 2010 IOP Publishing Ltd.

Ravichandran V.,Sri Kgs Arts College | Chinnathambi V.,Sri Kgs Arts College | Rajasekar S.,Bharathidasan University
Pramana - Journal of Physics | Year: 2012

We study the nonlinear resonance, one of the fundamental phenomena in nonlinear oscillators, in a damped and periodically-driven Duffing oscillator with two types of time-delayed feedbacks, namely, fixed and integrative. Particularly, we analyse the effect of the time-delay parameter α and the strength γ of the time-delayed feedback. Applying the perturbation theory we obtain a nonlinear equation for the amplitude of the periodic response of the system. For a range of values of γ and α, the response amplitude is found to be higher than that of the system in the absence of delayed feedback. The response amplitude is periodic on the parameter a with period 2p/ω where ω is the angular frequency of the external periodic force. We show the occurrence of multiple branches of the response amplitude curve with and without hysteresis. © Indian Academy of Sciences.

Jeyakumari S.,Sri Kgs Arts College | Chinnathambi V.,Sri Kgs Arts College | Rajasekar S.,Bharathidasan University | Sanjuan M.A.F.,Rey Juan Carlos University
International Journal of Bifurcation and Chaos | Year: 2011

We analyze how the asymmetry of the potential well of the Duffing oscillator affects the vibrational resonance. We obtain, numerically and theoretically, the values of the low-frequency and amplitude of the high-frequency forces at which vibrational resonance occurs. Furthermore, we observe that an additional resonance is induced by the asymmetry of the potential well. We account the additional resonance in terms of resonant frequency of the slow motion of the system. Resonance occurs in the asymmetric system for the input signal frequency range for which it is not possible in the symmetric system. Resonance is also studied with nonsinusoidal input signals and in the presence of additive Gaussian white noise. © 2011 World Scientific Publishing Company.

Thangakrishnakumari S.,Sri Kgs Arts College | Nishanthini A.,Ethnopharmacology Unit | Muthukumarasamy S.,Sri Kgs Arts College | Mohan V.R.,Ethnopharmacology Unit
Asian Journal of Pharmaceutical and Clinical Research | Year: 2013

Objective: To evaluate the hypoglycemic and hypolipidemic effects of ethanol extract of Sarcostemma secamone whole plant in alloxan induced diabetic rats. Methods: Diabetes was induced in Albino rats by administration of alloxan monohydrate (150mg/kg i.p). The ethanol extracts of Sarcostemma secamone whole plant at a dose of 150 and 300 mg/kg of body weight were administrated at a single dose per day to diabetes induced rats for a period of 14 days. The effect of ethanol extract of Sarcostemma secamone whole plant extract on blood glucose, plasma insulin, urea, creatinine, glycosylated haemoglobin, serum lipid profile [total cholesterol (TC), triglycerides (TG), low density lipoprotein-cholesterol(LDL-C), very low density lipoprotein-cholesterol (VLDL-C), high density lipoprotein- cholesterol (HDL-C) and phospholipid (PL), serum protein, albumin, globulin, serum enzymes [serum glutamate pyruvate transaminases] (SGPT), serum glutamate oxaloacetate transaminases (SGOT) and alkaline phosphatase (ALP)] were measured in the diabetic rats. Results: In the acute toxicity study, ethanol extract of Sarcostemma secamone whole plant was non-toxic at 2000 mg/kg in rats. The increased body weight, decreased blood glucose, glycosylated haemoglobin and other biochemical parameters level was observed in diabetic rats treated with both doses of ethanol extract of Sarcostemma secamone whole plant compared to diabetic control rats. In diabetic rats, ethanol extract of Sarcostemma secamone whole plant administration, altered lipid profiles were reversed to near normal than diabetic control rats. Conclusion: Ethanol extract of Sarcostemma secamone whole plant possess significant hypoglycemic and hypolipidemic activity in diabetic rats.

Valarmathi M.,Nkr Government Arts College W | Gomathi A.,Sri Kgs Arts College | Manisankar P.,Alagappa University
International Journal of Environmental Analytical Chemistry | Year: 2013

The voltammetric behaviour of two anthraquinone dyes such as Alizarin Red S (ARS) and Reactive blue 4 (RB4) was investigated at plain glassy carbon electrode (GCE), multiwalled carbon nano tube modified GCE (MWCNT/GCE) and zeolite modified GCE (ZE/GCE) using cyclic voltammetry. Effects of pH, scan rate and concentration were studied. The surface morphology of the modified electrode in the absence and presence of dye molecules was characterized by scanning electron microscopy (SEM). A systematic study on the variation of experimental parameters with differential pulse stripping voltammetry (DPSV) was carried out and the optimized experimental conditions were arrived. MWCNT/GCE performed well among the three electrode systems and the limit of detection (LOD) was 0.036 μg mL-1 for ARS and 0.05 μg mL-1 for RB4 on this modified system. Suitability of the differential pulse stripping voltammetric method for the trace determination of textile dyes in effluents was also realized. © 2013 Copyright Taylor and Francis Group, LLC.

Thanga Krishna Kumari S.,Sri Kgs Arts College | Muthukumarasamy S.,Sri Kgs Arts College | Mohan V.R.,Ethnopharmacolgy unit
Journal of Applied Pharmaceutical Science | Year: 2012

In the present study, the bioactive components of Canscora perfoliata whole plant have been evaluated using GC-MS. The chemical compounds of the ethanol extract of Canscora perfoliata Lam. were investigated using Perkin-Elmer Gas chromatography-Mass spectrometry. GC-MS analysis of ethanol extracts of Canscora perfoliata revealed the existence of seventeen compounds. This is the first report of identification of active constituents from the whole plant of Canscora perfoliata Lam.

Loading Sri Kgs Arts College collaborators
Loading Sri Kgs Arts College collaborators