Sri Guru Ram Rai Institute of Medical and Health science

Dehradun, India

Sri Guru Ram Rai Institute of Medical and Health science

Dehradun, India
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Nautiyal N.,Sri Guru Ram Rai Institute of Medical and Health Science | Bhardwaj A.,Sri Guru Ram Rai Institute of Medical and Health Science | Acharya S.,Sri Guru Ram Rai Institute of Medical and Health Science | Kishore S.,Sri Guru Ram Rai Institute of Medical and Health Science | Kudesia S.,Sri Guru Ram Rai Institute of Medical and Health Science
Journal of Clinical and Diagnostic Research | Year: 2017

Introduction: Fluid cytology and subsequent utilization of immunocytology on cell block is being used commonly for increasing the diagnostic accuracy in effusion cytology. Aim: To do cytological analysis of fluids and evaluate the role of Epithelial Membrane Antigen (EMA) and Calretinin (CAL) to differentiate between reactive and malignant cell in pleural and peritoneal fluids. Materials and Methods: This was a prospective study carried out in Department of Pathology, Shri Guru Ram Rai Institue of Medical and Health Science, for a period of 18 months from January 2014 to June 2015. A total of 253 samples of pleural and peritoneal fluid were studied by May-Gruenwald-Giemsa (MGG) stain and Papanicolaou (Pap) staining. In 73 cases which were suspicious for malignancy, cell blocks were prepared and IHC was done using two immunomarkers- EMA and CAL. Results: A total of 253 cases of effusion cytology were studied out of which 73 were found positive for malignant cells. Maximum cases of malignant cells or atypical cells were seen in peritoneal fluid. A total of 34 cases were histologically positive for malignancy. All these cases showed strong membranous and cytoplasmic positivity for EMA. Most of cases also showed 2%-5% positivity for CAL. There were 38 cases categorized as atypical or reactive mesothelial cell hyperplasia. These cases showed nuclear and cytoplasmic staining for calretinin and none of these were positive for EMA, although 5 cases showed score 2-3, which was considered as negative. Conclusion: The distinction between reactive and malignant mesothelial cells in cytological specimens can be problematic. A combination of CAL and EMA may help in accurate diagnosis. © 2017, Journal of Clinical and Diagnostic Research. All rights reserved.


Pandey A.K.,Sri Guru Ram Rai Institute of Medical and Health science | Bhardwaj A.,Sri Guru Ram Rai Institute of Medical and Health science | Maithani T.,Sri Guru Ram Rai Institute of Medical and Health science | Rathi S.,Sri Guru Ram Rai Institute of Medical and Health science
Clinical Rhinology | Year: 2016

Pleomorphic adenomas occurring in the nasal cavity are rarely encountered; nevertheless, there is abundance of minor seromucinous glands in that region. Most cases present with a painless, slowly progressing unilateral nasal obstruction, a nasal mass, and epistaxis. Herewith, we present an unusual case of pleomorphic adenoma arising from the lateral wall of the right nasal cavity in a 41-year-old male who complained of right nasal obstruction with no history of epistaxis. Rigid nasal endoscopy revealed a swelling continuous with right inferior concha. Computed tomography showed a well-defined, soft tissue mass in the right nasal cavity. The lesion was completely excised endoscopically. Histopathology confirmed a pleomorphic adenoma consisting of epithelial and mesenchymal elements. Wide exposure is crucial for complete excision with negative margins to achieve positive outcome and to prevent recurrence. © 2016, Jaypee Brothers Medical Publishers (P) Ltd. All rights reserved.


PubMed | Sri Guru Ram Rai Institute of Medical and Health Science and Maulana Azad Medical College
Type: Journal Article | Journal: Journal of orthopaedic case reports | Year: 2017

Volumes have been written and practiced in relation to the crush injuries involving hands, over the decades. Mutilated hand and its treatment demands a thorough knowledge of rehabilitative techniques, and an in depth knowledge about the anatomy of hand, in order to achieve successful outcomes in its treatment.We present three cases of mutilated hand due to being crushed in a sugarcane machine. All three patients were males, with the age of 14yrs, 30yrs and 34yrs respectively.Mutilated hand injuries must be treated aggressively and efficiently which is essential to achieve good functional results. Any delay in effective management may lead to stiffness and very poor functional results.


Luthra M.,Sri Guru Ram Rai Institute of Medical and Health science | Varma A.,Sri Guru Ram Rai Institute of Medical and Health science | Gupta S.K.,Sri Guru Ram Rai Institute of Medical and Health science | Negi K.S.,Sri Guru Ram Rai Institute of Medical and Health science
Indian Journal of Community Health | Year: 2015

Introduction: Scrub Typhus is a trombiculid mite-borne rickettsial zoonosis caused by Orientia tsutsugamushi, which is widely endemic in the Asia-Pacific region and threatens a population of millions. Aim and Objectives: To study epidemiology and clinical profile of Scrub Typhus Cases in a clinical setting and to clarify current diagnostic issues of scrub typhus. Materials and methods: Study period was August to December 2014. 197 clinical cases confirmed by positive result in immunoglobulin (IgG, IgM or IgA) using a rapid immuno-chromatographic assay (Bioline SD Tsutsugamushi One Step Scrub typhus Antibody test) were included. Results: 27.4% cases were in the age group of 20-30 years followed by cases in the age group of 10-20 as well as 40-50 years (15.7%). More than half of all the cases were female (58.4%). 29.9% were still studying and and 17.8% were illiterate/just literate. 29.4% cases were from district Dehradun followed by cases from district Saharanpur (25.4%). Most cases were not working, i.e. were housewives (42.6%) followed by students (29.9%). Most common presenting features were fever with gastro-intestinal symptoms (51.3%). All the cases were treated with appropriate antibiotics (Doxycycline, Azithromycin and a higher generation cephalosporin for secondary complications). 38.1% cases went on to develop a complication during their hospital stay. All were discharged in satisfactory condition except for two mortalities during the study period. © 2015, Indian Association of Preventive and Social Medicine. All rights reserved.


Pandey A.K.,Sri Guru Ram Rai Institute of Medical and Health science | Maithani T.,Sri Guru Ram Rai Institute of Medical and Health science | Bhardwaj A.,Sri Guru Ram Rai Institute of Medical and Health science
Egyptian Journal of Ear, Nose, Throat and Allied Sciences | Year: 2014

Kartagener's syndrome is a rare congenital disorder consisting of sinusitis, bronchiectasis with situs inversus and is associated with infertility. It is the subgroup of disorder called primary ciliary dyskinesia in which well defined morphological or functional abnormalities of cilia result in sinopulmonary involvement with varying severity. Clinical manifestations involve chronic and/or recurrent respiratory infections with much heterogeneity in multisystem involvement. Early diagnosis and management of this condition help to prevent irreversible lung damage and prevent chronic lifelong sequelae. © 2014 Hosting by Elsevier B.V.


Jain N.,Sri Guru Ram Rai Institute of Medical and Health science | Verma P.,Sri Guru Ram Rai Institute of Medical and Health science | Mittal S.,Sri Guru Ram Rai Institute of Medical and Health science | Singh A.K.,Sri Guru Ram Rai Institute of Medical and Health science | Munjal S.,Sri Guru Ram Rai Institute of Medical and Health science
Indian Journal of Physiology and Pharmacology | Year: 2010

Human beings are able to perceive hundreds of shades of color which depends on the three types of cone system and various ratios of stimulation in response to different wavelengths. Perceptually and cognitively, men and women may experience appearance of color differently. Therefore, this study was planned to assess and compare color vision in male and female subjects. This study was carried out in the department of Physiology, SGRRIM&HS, Dehradun on 60 ocular healthy subjects (equal number of males and females) of 17-22 years of age group. The task was to match 22 test color strips with 2 shade charts of different colors. Total number of correct answers and total time taken in matching all the test color strips with the shade charts was recorded in both the sexes and analyzed. The results of this study showed that overall, females gave more correct responses (P<0.001) and also took less time (P<0.01) than males. Color wise also, females gave more correct responses especially for red (P<.001) and green color (P<0.01). The conclusion states that the females can see more shades of colors than males.


Aggarwal B.,Sri Guru Ram Rai Institute of Medical and Health science | Rana S.K.,Sri Guru Ram Rai Institute of Medical and Health science | Chhavi N.,Sri Guru Ram Rai Institute of Medical and Health science
JK Science | Year: 2014

Poisoning is a common medical emergency in children. Most of the poisoning in children is accidental. Unfortunately, the incidence of deliberate poisoning among adolescents is increasing due to changing familial and social conditions in our society. Study design: prospective analysis of poisoning seen in children between January 2010 and December 2013 in an academic center of northern India. Results: Eighty one children (Boys 45, 55%; age median [range] 13 [1-18]) were included. All poisoning episodes were either suicidal (38, 46.9%) or accidental (43, 53.1%). Most of the poisoning events in pre-adolescent children were accidental (34/35, 97%) and among adolescents (13-18 years age group) were suicidal (37/45, 80.4%). The most commonly ingested poisoning agent was kerosene (10/35, 28.6%) in <12 age group and organo-phosphorus compound (8/37, 21.6%) in adolescents. Conclusion: We need to take preventive measures for accidental and intentional poisoning in pre-adolescents and adolescents age group respectively. © 2014, JK Science. All rights reserved.


Agrahari A.K.,Sri Guru Ram Rai Institute of Medical and Health science | Roy S.,Banaras Hindu University | Jain R.K.,Banaras Hindu University
Otorhinolaryngology Clinics | Year: 2014

A unique case of a 5 cm long impacted broken toothbrush in nasopharynx of a 3-year-old male child is being reported. The foreign body remained impacted for a long period of 8 months. The toothbrush was visualized transnasally by endoscopy and removed per oral under general anesthesia. © 2014, Jaypee Brothers Medical Publishers (P) Ltd. All rights reserved.

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