Sri Gokulam Hospital and Research Institute

Salem, India

Sri Gokulam Hospital and Research Institute

Salem, India
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Nagaraja S.B.,ESIC Medical College and PGIMSR | Mittal A.,Nepalese Army Institute of Health science | Rajesh E.,Mahatma Gandhi University | Senthilkumaran S.,Sri Gokulam Hospital and Research Institute | And 2 more authors.
Asian Pacific Journal of Cancer Prevention | Year: 2014

Background: Breast cancer is the second most common cancer in the world and by far the most frequent cancer among women. Objective: The present study was undertaken to assess the awareness of breast cancer warning signs and screening methods among the women of Pokhara valley, Nepal. Materials and Methods: A cross-sectional questionnaire survey was carried out in a community setting with the female population. The questionnaire was administered in face-to-face interviews by trained research assistants. Results: Nepalese women demonstrated poor awareness of warning signs like a breast lump, lump under the armpit, bleeding or discharge from the nipple, pulling of the nipple, changes in the position of the nipple, nipple rash, redness of the breast skin, changes in the size of the breast or nipple, changes in the shape of the breast or nipple, pain in the breast or armpit, and dimpling of the breast skin. While 100% of nurses were aware about breast self-examination (BSE), mammography and warning signs of breast cancer. Levels of knowledge were significantly poorer in women with other occupations. Graduates were more aware about BSE, mammogram and warning signs of breast cancer compared to those with other educational levels. Conclusions: The findings indicated that the level of awareness of breast cancer, including knowledge of warning signs and BSE, is sub-optimal among Nepalese women.


Senthilkumaran S.,Sri Gokulam Hospital and Research Institute | Balamurugan N.,Manipal Hospital | Vohra R.,University of California at San Francisco | Thirumalaikolundusubramanian P.,Chennai Medical College Hospital and Research Center
International Journal of Trichology | Year: 2012

Selenium is a micronutrient. It presents a nutritional conundrum because of its twin status as an essential as well as a highly toxic trace element. Here, we report a case of acute non-intentional selenium toxicity due to increased ingestion of paradise nuts (Lecythis ollaria) which resulted in massive alopecia.


Fazil A.,Manipal University India | Vernekar P.V.,Srinivas Institute of Medical science and Research Center | Geriani D.,Kasturba Medical College | Pant S.,University of Arkansas for Medical Sciences | And 4 more authors.
Journal of Infection and Public Health | Year: 2013

Background: This study was designed to study the patient characteristics, presenting features and complications of malaria in patients with elevated liver enzymes and to compare these data to those of patients with normal liver enzymes. Methods: A convenient sample of 100 patients with malaria was selected from three tertiary care referral hospitals. Study subjects were divided into two groups: (1) patients (controls) with normal liver enzymes and (2) patients (cases) with >3 times the normal liver enzymes in the absence of an alternate explanation for such elevation. Patient characteristics, presenting features and complications of malaria in these two groups were studied. Data were collected using a semi-structured pretested proforma and were analyzed using the statistical analysis program SPSS, version 11.5 (SPSS, Inc., Chicago, IL). Results: The mean ages were 38.12 years for the cases and 35.20 years for the controls with a non-significant p value of 0.289. Males composed 82% of the cases that were diagnosed with malarial hepatopathy; the remaining 18% were females. Falciparum malaria was present in 56% of the cases, compared to 12% of the controls. Icterus was present in 66% of cases of malarial hepatopathy, compared to 32% of the controls. Of the 66% of these cases, 18.18% had serum bilirubin >3. mg%, whereas out of the 32% of the controls presenting with icterus, only 5.55% had serum bilirubin >3. mg% (p=0.003). Of the cases with malarial hepatopathy, 38% suffered from hypoglycemia, compared to 0% of the controls (p< 0.001); 84% of the cases presented with thrombocytopenia, compared to 70% of the controls (p< 0.001); 12% of the cases suffered from renal failure with serum creatinine levels >2. mg%, compared to 2% of the controls (p= 0.060). Conclusion: Plasmodium falciparum infection (either alone or along with P. vivax) is the leading cause of malarial hepatopathy. Jaundice is a common clinical manifestation among these patients. Patients with malarial hepatopathy have increased incidences of hypoglycemia and thrombocytopenia. Malarial hepatopathy occurs in relation to severe infection, most of which are treated with parenteral artesunate. © 2013 King Saud Bin Abdulaziz University for Health Sciences.


Menezes R.G.,Srinivas Institute of Medical science and Research Center | Pant S.,University of Arkansas for Medical Sciences | Kharoshah M.A.,Forensic Medicine Authority | Senthilkumaran S.,Sri Gokulam Hospital and Research Institute | And 7 more authors.
Legal Medicine | Year: 2012

Malaria inflicts a huge health care burden in terms of mortality and morbidity worldwide. There has been evidence in the literature where many unexpected/unexplained deaths turned out to be related to malaria on autopsy. The aim of this study is to review autopsy diagnosed malaria related deaths in the literature with due stress to its biologic and forensic aspects. A meticulous literature search was performed for " sudden malaria death" , " malaria death postmortem diagnosis" and " unexplained death malaria" across PubMed, SCOPUS, Cochrane Database of Systematic Reviews, Allied and Complementary Medicine, British Nursing Index, CINAHL, EMBASE, Ovid-MEDLINE and Google Scholar. All the literature was thoroughly reviewed and analyzed with reference to the type of study, location, travel history, age, gender, circumstance of death, method of diagnosis, species involved, chemoprophylaxis usage and take home message from the particular study. Plasmodium falciparum was responsible in most of the cases. The symptoms mimicked influenza in most of the case reports. Travel to endemic areas was common to most of the victims. The travelers were from all over the world including USA, France, Switzerland, Spain, Portugal, Germany and Asia (China and Japan). Vascular congestion with the presence of malarial pigment laden RBCs in capillaries of various organs was the major histopathology finding. Such lesions were found in the brains of all subjects (100%), liver of 78% of the cases, spleen in 67%, lungs in 56% and myocardium in 43% of the cases. Peripheral smear and rapid diagnostic test was of great aid to the autopsy in many cases. PCR was used for diagnosis as well as exclusion of possibility of co-infection with other species in case of Plasmodium knowlesi related death. The postmortem and histopathology findings in this case were similar to P. falciparum except for the fact that brain sections were negative for intracellular adhesion molecule-1. Chemoprophylaxis was not taken by the victims except for two in whom history of chloroquine based chemoprophylaxis was mentioned. Given the worldwide prevalence of the disease, increasing international travel and rapidly developing drug resistance, malaria will continue to be an important disease and should be considered in all cases of unexpected deaths particularly in malaria endemic regions or in presence of travel history to endemic regions. © 2012 Elsevier Ireland Ltd.


Senthilkumaran S.,Sri Gokulam Hospital and Research Institute | Menezes R.G.,Srinivas Institute of Medical science and Research Center | Pant S.,University of Arkansas for Medical Sciences | Thirumalaikolundusubramanian P.,Chennai Medical College Hospital and Research Center
Wilderness and Environmental Medicine | Year: 2013

Snake bite is an environmental and occupational hazard in many tropical and subtropical countries. It demands a high level of knowledge and skill in managing the envenomation syndrome. Herein, we describe a rare case of acute acalculous cholecystitis (AAC) that developed in a 36-year-old man after an Indian cobra (Naja naja) bite in the absence of any other predisposing factors for AAC. The probable mechanisms for the occurrence of AAC have been highlighted. Recognizing the possibility of such a complication after envenomation will definitely aid in early diagnosis and, subsequently, a better outcome. © 2013 Wilderness Medical Society.


Subba S.H.,Manipal University India | Pant S.,University of Arkansas for Medical Sciences | Senthilkumaran S.,Sri Gokulam Hospital and Research Institute | Menezes R.G.,Srinivas Institute of Medical science and Research Center
Egyptian Journal of Forensic Sciences | Year: 2011

Battered child syndrome, battered baby syndrome, shaken baby syndrome, non-accidental injuries of childhood, etc. are all variants of forms of child abuse that has many names but a single outcome - the child is injured at the hands of a caretaker, more often than not a close relative. Although there are clear guidelines in most developed countries as to what the clinicians should do if they suspect a case of battered child syndrome, no such specific streamlined guidelines exist in most of the developing countries including India. In India, the National Commission for Protection of Child's Rights and the Indian Academy of Pediatricians have recently taken the initiative to educate pediatricians about child abuse and formulate policies on reporting. Although the pediatricians have woken up to the reality of child abuse, rest of the medical fraternity is yet to wake up to the fact that a big proportion of children in India are being battered and most go unnoticed and unreported. In India, there is a need for the medical and nursing educators, practitioners, policy makers, political and legislative wings of the society to get together and raise awareness, formulate specific guidelines regarding the management of a case of suspected battered child; who should investigate and how the investigation has to be done, how to ensure safe settings for at-risk children and facilitate permanent placement for children who cannot return home. © 2011 .


Senthilkumaran S.,Sri Gokulam Hospital and Research Institute | Balamurugan N.,Sri Gokulam Hospital and Research Institute | Suresh P.,Sri Gokulam Hospital and Research Institute | Thirumalaikolundusubramanian P.,Chennai Medical College and Research Center
Urology Annals | Year: 2012

We report the development of low flow priapism in three patients related to simultaneous consumption of sildenafil with pomegranate (Punica granatum) (POM) juice. There were no other concurrent diseases, intake of drugs, and chemicals or other risk factors in these patients. We want to create awareness among patients and practitioners for recognition and timely intervention. Probable mechanisms are highlighted.


Senthilkumaran S.,Sri Gokulam Hospital and Research Institute | Sweni S.,Debrecen University | Ganapathysubramanian,Sri Gokulam Hospital and Research Institute | Suresh P.,Sri Gokulam Hospital and Research Institute | Thirumalaikolundusubramanian P.,Chennai Medical College and Research Center
International Journal of Gerontology | Year: 2011

Successful removal of a live fish impacted in the hypopharynx of a 65-year-old male is reported to emphasize the importance of the speed with which it has to be recognized and intervened. The present report also highlights the altered sensory perception in the oral cavity of elderly people as a potential risk factor for airway obstruction due to a foreign body. Moreover, the possibility of a foreign body has to be suspected, if an elderly patient without any cardiorespiratory illness presents with an acute onset of progressive respiratory distress. Copyright © 2011, Taiwan Society of Geriatric Emergency & Critical Care Medicine. Published by Elsevier. Taiwan LLC. All rights reserved.


PubMed | University of Dammam, Manipal University India, Sri Gokulam Hospital and Research Institute and Forensic Medicine Authority
Type: Case Reports | Journal: La Clinica terapeutica | Year: 2014

During the medico-legal autopsy of a male aged 45 years, a bilobed morphology of the spleen was observed. An oblique fissure was located longitudinally at the mid-region of the diaphragmatic surface of the spleen. The fissure was partially deep and observed throughout the diaphragmatic surface. The clinician should be aware of the developmental anomalies of the spleen; as such anomalies may cause confusion during the procedures like splenic biopsy and splenectomy. We believe that, the present case report is important to the radiologists and clinicians involved in the diagnosis and management of splenic pathology. The knowledge is also enlightening to the morphologists and embryologists. The radiologist and clinician should make sure that the fissure in a spleen is not misinterpreted as a laceration or rupture.


PubMed | Sri Gokulam Hospital and Research Institute
Type: Case Reports | Journal: Pediatric emergency care | Year: 2012

Unintentional organophosphate compound poisoning, although known, contamination of organophosphate compound through laundered uniform and subsequent transcutaneous absorption, in 30 children is reported herewith for its rarity. Emergency physicians have to recognize such entities clinically, confirm by laboratory means wherever possible, and intervene with appropriate measures.

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