Sree Siddhartha Medical College

Tumkūr, India

Sree Siddhartha Medical College

Tumkūr, India
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Pavithra P.,Sree Siddhartha Medical College | Arathi C.A.,Melaka Manipal Medical College | Jayashree J.B.,District hospital
Biomedicine (India) | Year: 2016

Heterotopia is the occurrence of mature tissue at an abnormal location. Cartilaginous heterotopia is seen in several organs, but its occurrence in the omentum is extremely rare. Here, we report a case of incidental detection of chondroid heterotopia in the omentum, not associated with any intra-Abdominal malignancy, in a 35-year-old female during lower segment caesarean section. Omental nodule measured 1x1cm with a glistening surface and microscopy revealed nodules of mature hyaline cartilage surrounded by fibrous and adipose tissue. These may be due to the peritoneal response to previous intraoperative manipulation or could be from multipotent submesothelial rests.

PubMed | Rajiv Gandhi Institute of Public Health and Center for Disease Control, Sree Siddhartha Medical College and National Institute of Mental Health and Neuro Sciences
Type: Journal Article | Journal: Bulletin of emergency and trauma | Year: 2016

To assess the availability of trauma care services in a district referral hospital of Southern India.This was a cross-sectional study being performed during 2013 in a tertiary healthcare centre in Southern Indian. A detailed assessment of trauma care services was done in a 400 bed speciality hospital which is an apex referral hospital in the public health system using a check list based on WHO guidelines for evaluation of essential trauma care services, along with in-depth interviews of hospital stake holders and key informants.The hospital had physical infrastructure in terms of emergency room, inpatient wards, operation theatres, intensive care unit and blood bank facilities. The recently constructed designated building for trauma care services was not operational and existing facilities were used beyond capacity. A designated trauma team was lacking and speciality services for managing polytrauma were deficient and thus, existing personnel were performing multiple tasks. Neurosurgeons and rehabilitative nursing staff were unavailable, and a radiographer was not available on a 24/7 basis. Existing nursing personnel had not received any formal training in trauma care and standard operating protocols were not available for trauma care. Resources for acute resuscitation were partially adequate. The hospital lacked adequate resources to manage head, abdomen, chest and spine injuries, and most of the polytrauma cases were referred to nearby city hospitals.District hospital, the only referral hospital in public health system for trauma victims of that region, had inadequate resources to manage trauma victims, which was probably responsible for delay in trauma care, improper referrals, high cost of care and poor outcomes.

PubMed | Sree Siddhartha Medical College and Christian Medical College
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2016

We present a few cases of Proximal Interruption of the Pulmonary Artery, an uncommon developmental anomaly associated with congenital heart disease. The cases had varied clinical presentations. Chest radiograph showed a hypoplastic lung with an ipsilateral small hilum on the side of the interruption and hyperinflation of the contralateral lung. Contrast CT confirmed the diagnosis, demonstrating non-visualization of the left or right pulmonary artery, and other related findings.

Arundhathi S.,Sree Siddhartha medical college | Sunitha S.,Basaweshwara medical college
International Journal of Pharma and Bio Sciences | Year: 2014

Diagnosis by direct immunofluorescence (DIF) requires skin biopsies with preserved immunoreactants for which biopsies are snap-frozen in liquid nitrogen or placed in Michel's fixative that facilitates transport. Retrospective study was conducted on 30 perilesional skin biopsies of immune- vesciculobullous lesions in Michel's medium to analyse its efficiency as transport medium. DIF was performed and samples were grouped according to the number of days they had been maintained in Michel's medium. DIF was positive in 28 cases, accounting for 93.33%. DIF was positive in 100%, 92.31% and 83.33% of biopsies even after 5, 10 and 15 days of preservation in Michel's medium, respectively. As the number of days in transport medium increased, the intensity of immunofluorescence decreased. There was no statistical significance (>0.05) between the intensity of immunofluorescence and the number of days the biopsies were in transport medium. Michel's medium is an efficient transport medium, when used within 15 days, in countries where DIF facilities are not available.

Geetha J.P.,Sree Siddhartha Medical College | Pavithra P.,Sree Siddhartha Medical College
Biomedicine (India) | Year: 2015

Introduction: Fine needle aspiration cytology (FNAC) is a reliable and inexpensive diagnostic method in developing countries for the diagnosis of primary and secondary malignant disorders involving the lymph nodes. Aim: To study the role of FNAC in the diagnosis of suspected and unsuspected lymph node malignancies. Materials and Methods: A prospective study was done on all lymph node lesions over a period of three years in a tertiary care hospital. FNAC was performed with a 23 gauge needle; slides were prepared, stained and examined microscopically. Results: Out of 320 cases of lymph node FNACs, a total of 65 nodes were reported as "positive for metastasis. The most common subtype of metastatic malignant tumor was squamous cell carcinoma in 36 cases (55.38 %) followed by poorly differentiated carcinoma in 16 (24.61%), adenocarcinoma in 3 (4.61%), breast ductal Carcinoma in 3 (4.61%), papillary carcinoma thyroid in 3 (4.61%), nasopharyngeal carcinoma in 2 (3.01%), anaplastic carcinoma thyroid and malignant melanoma in 1 each (1.54 %). Majority (53.84%) of the patients belonged to the age group of 50-70 years with a male preponderance. Cervical group of lymph nodes were most Commonly involved. Conclusion: FNAC is a safe, rapid and accurate method for diagnosing metastatic lesions with good certainty. It confirms the presence of metastasis, gives a clue to the origin of primary tumor, prognosis as well as Management of patients for staging purposes.

Arathi C.,Sree Siddhartha Medical College | Vijaya C.,Sree Siddhartha Medical College
Journal of Cytology | Year: 2010

The low incidence and the non-specific clinical symptoms led us to conclude that the diagnosis of a sebaceous carcinoma of the eyelid often occurs very late. Sebaceous carcinoma of the ocular adnexa is a malignant neoplasm which can exhibit aggressive local behavior, can have pagetoid spread and can metastasize to regional lymph nodes and distant organs. The neoplasm is known to masquerade as other benign and less malignant lesions, and has relatively high morbidity and mortality. Scrape cytology was done in a 70-year-old female with a tumor in left upper lid. Cytological smears were suggestive of sebaceous carcinoma. Subsequently, histopathology confirmed the diagnosis of sebaceous gland carcinoma. The article highlights the role of scrape cytology in early diagnosis and subsequent appropriate surgical management of eyelid sebaceous gland carcinoma, to prevent recurrence and metastasis.

Pavithra P.,Sree Siddhartha Medical College | Rashmi M.V.,Sree Siddhartha Medical College
International Journal of Pharma and Bio Sciences | Year: 2014

Fine needle aspiration cytology (FNAC) has become an accepted and cost effective procedure for preoperative diagnosis of thyroid lesions. Present study was carried out to study the spectrum of thyroid lesions on cytology and to evaluate the diagnostic accuracy of FNAC in palpable thyroid lesions by comparing with histopathology wherever available. Total of 250 cases of thyroid swellings were aspirated over a period of 5 years in a tertiary care hospital. Cytologically, the cases were classified into 5 groups, namely, benign, inadequate, suspicious, malignant and cellular follicular lesions. There were 221 benign cases, 11 malignant, 2 suspicious, 6 inadequate and 10 with cellular follicular lesions. FNAC reports were compared with histopathology results and statistical indices were calculated. The sensitivity, specificity and diagnostic accuracy were 75.86% & 58.82%, 100% & 76.47% and 89.70% & 72.05% respectively considering suspicious cases alternatively as positives and negatives. FNAC is a highly sensitive and specific test with high diagnostic accuracy for preoperative evaluation of patients with thyroid swelling.

Srinivasa Reddy P.,Sree Siddhartha Medical College
Indian Journal of Forensic Medicine and Toxicology | Year: 2012

A 23 year old male, complained of chest pain and breathlessness on getting up from bed in the early morning at 4.00 AM. On arrival at the casualty of Sri Siddhartha Medical College Hospital, Tumkur, he was declared brought dead to the hospital by the casualty medical officer at 6.15 AM on 8/7/09. Autopsy was conducted in the Department of Forensic Medicine, revealed no demonstrable changes in the myocardium except obstruction to the left coronary main trunk.

Pavithra P.,Sree Siddhartha Medical College | Geetha J.P.,Sree Siddhartha Medical College
International Journal of Pharma and Bio Sciences | Year: 2014

Fine needle aspiration cytology (FNAC) is a reliable and an inexpensive method for diagnosis of palpable masses at various sites. FNAC was performed on 319 patients with palpable lymphadenopathy over a period of three years. Ziehl Neelson staining was done wherever required. Clinicocytological correlation was done. FNAC diagnosis was found to be as follows: tubercular lymphadenitis in 135 cases (42.31%) followed by metastatic carcinoma in 64 (20.06%), reactive hyperplasia in 56 (17.55%), granulomatous lymphadenitis in 37 (11.59%), suppurative granulomatous in 10 (3.13%), suppurative lymphadenitis in 6 (1.88%) and lymphoma in 5 (1.56%). Aspirates were inadequate in 6 (1.88%) cases. FNAC is a useful and reliable tool in diagnosing non neoplastic and neoplastic lesions of lymph nodes and helps in making a wise decision in further management of patients as reactive and tubercular lymphadenitis can be treated conservatively while surgery might be required for malignant cases.

Manjunath M.K.,Sree Siddhartha Medical College | Annam V.,Sree Siddhartha Medical College | Suresh D.R.,Sree Siddhartha Medical College
Journal of Laryngology and Otology | Year: 2010

Background and objectives: Laryngeal and hypopharyngeal cancer is a multifactorial disease caused by various carcinogens such as tobacco, alcohol and viruses. Likewise, oxidative stress is known to cause aberrations in the cell membrane and DNA, leading to cancer. We conducted this prospective study in order to evaluate the level of oxidative stress in laryngeal and hypopharyngeal cancer patients. Methods: Fifty patients with laryngeal and hypopharyngeal cancer and 40 control subjects were selected. Serum malondialdehyde concentrations and ferric reducing antioxidant power were assessed, in order to evaluate oxidative stress. Results were analysed by Student's t-test.Results: Malondialdehyde levels were significantly higher and ferric reducing antioxidant power lower in the cancer patients, compared with the controls, indicating higher oxidative stress in the former. There was no statistically significant difference in malondialdehyde concentration or ferric reducing antioxidant power, comparing patients with versus without neck secondaries, and patients with early stage versus late stage tumours. Conclusion: Oxidative stress may have a role to play in the initiation of laryngeal and hypopharyngeal cancers, especially in patients with other risk factors such as tobacco and alcohol use. Copyright © JLO (1984) Limited 2009.

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