Sree Narayana Guru College

Coimbatore, India

Sree Narayana Guru College

Coimbatore, India
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Rafiqkhan M.,Sree Narayana Guru College | Saranya,Sree Narayana Guru College
International Journal of Pharmacy and Pharmaceutical Sciences | Year: 2013

Objective: Medicinal plants have played a significant role in ancient traditional systems of medication in many countries. Achyranthes aspera Linn is one of the important medicinal plants having many therapeutic uses. The present study deals with pharmacognostic profile and preliminary phytochemical investigations of Achyranthes aspera Linn. Method: Various parameters like fluorescence analysis of powdered as well as its extractives and phytochemical screening of different extractives were studied. Result: Phytochemical screening of the plant revealed the presence of phenolics, flavonoids, tannins, alkaloids, proteins and carbohydrates. Conclusion: The present study revealed that Achyranthes aspera Linn is an important source of many therapeutically and pharmacologically active constituents. The plant has been widely studied for its pharmacological activities and finds its position as a versatile plant having a wide spectrum of medicinal activities.

Sagadevan P.,Kongunadu Arts and Science College | Sagadevan P.,Sree Narayana Guru College | Suresh S.N.,Kongunadu Arts and Science College | Suresh S.N.,Sree Narayana Guru College
International Journal of PharmTech Research | Year: 2015

Antifungal and anticancer effect of the methanolic leaf extract of A. paniculata was studied against Candida albicans and MCF-7 cell lines, respectively. To determine anticancer activity, different concentrations of methanolic leaf extracts were tested on MCF-7, a human breast adenocarcinoma cell-line by 3-(4, 5 dimethyl thiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay. A. paniculata extracts showed a significant antiproliferative activity and a dose dependent effect was observed. Minimum inhibition of 9.47% was shown by extract at a concentration of 31.25 μg/ml and maximum inhibition of 99% was observed at 500 μg/ml. These results indicate the possible potential use of A. paniculata as Antineoplastic agent. © 2015, International Journal of PharmTech Research. All Rights Reserved.

Janaki C.,Lrggovt Arts College For Women | Jeyanthi V.,Sree Narayana Guru College
Procedia Computer Science | Year: 2014

The aim of this paper is to introduce and investigate a new decomposition of sets called πgμr-locally closed sets and a new decomposition of continuous maps called πgμr-LC continuous maps. Furthermore, we obtain several properties and characteristics of the new notions. © 2015 The Authors. Published by Elsevier B.V.

Lydia Rajakumari M.,Bharathiar University | Saravana Kumari P.,Sree Narayana Guru College
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2016

The largest diabetic population in India is around 50.8 million that could reach an epidemic proportion by 2030. The most common chronic oral diseases encountered worldwide are the oral infections seen in diabetes like the dental caries, gingivitis and periodontitis. The aim of the present study is to investigate the prevalence of oral bacterial flora in the buccal cavity of Diabetes mellitus individuals and control. A total of 400 buccal samples were collected from diabetic and non diabetic individuals (200 buccal samples each). Nutrient agar was used for the primary isolation of bacterial species. Morphological, Biochemical and Phylogenetic characterization along with additional tests using selective and differential media were used for identification. Results revealed that the normal oral flora in diabetic individual were higher, compared to non diabetic individuals. Staphylococcus aureus was the most predominant bacteria followed by Streptococcus species in diabetic individuals. In-vitro anti microbial susceptibilitytesting was performed using Amikacin (30mcg), Amoxicillin (30mcg), Erythromycin(15mcg), Gentamicin (30mcg) and Tetracycline (30mcg). Results showed that the antibiotics used in the test were effective against the isolated bacterial species. In-vitro antimicrobial susceptibility testing is needed for proper management of the disease.

Narayanasamy K.,Sree Narayana Guru College | Ragavan B.,P.A. College
E-Journal of Chemistry | Year: 2012

The present study reveals the phytochemical and mineral screening of Zanthoxylum tetraspermum W & A., a member of the family 'Rutaceae', which is used for treating microbial infections, antifungal activities and tooth ache. The preliminary screening of phytochemicals, thin layer chromatographic (TLC) profile of secondary metabolites and minerals from the stem bark of Zanthoxylum tetraspermum have shown the presence of various important secondary metabolites such as alkaloids, flavonoids, glycosides, Phenols, sterols, saponins, tannins in higher levels in hydroethnolic and aqueous extracts and some minerals in the plant extract. The generated data has provided the basis for its therapeutic value and can be used as a therapeutant.

Sandeep P.,Bharathiar University | Saravana Kumari P.,Sree Narayana guru college
International Journal of Pharma and Bio Sciences | Year: 2016

The study was aimed to evaluate the impact of probiotic bacteria on HEK-293 kidney cell lines and action on pathogenic microbes. The heat killed and live L.plantarum cultures were treated on the HEK 293 cell lines and on pathogenic bacteria. The percentage of viability of the cell line was carried out by using Trypan blue dye exclusion method, by mtt assay it was proved that different concentrations of Heat killed and live strains of L.plantarum were treated on HEK-293 human embryonic kidney cells. The cell viability was not affected by the liver as well as heat killed strains. An antimicrobial assay was carried out to see the action on pathogens. The strain was most effective against gram positive Staphylococcus aureus and least effective against Shigella flexneri. The heat killed strain of L.plantarum is not harming the cell lines and works against pathogens.

Lydia Rajakumari M.,Bharathiar University | Saravana Kumari P.,Sree Narayana Guru College
International Journal of Pharma and Bio Sciences | Year: 2016

Our aim is to determine the bacterial flora in the oral cavity of diabetic individuals in Pondicherry. In this study 200 buccal swabs from Diabetic individuals from age group 35±30 were included in the study. Blood Agar was used for the primary isolation of the bacterial isolates. Morphological, biochemical and phylogenetic classification were used for the identification of bacteria. Gram positive bacteria were predominant organisms in the oral cavity of diabetic individuals. Disturbances caused by the changes in the normal flora may lead to changes in the oral cavity, this may cause pathogenic micro flora to multiply and further lead to diseases. The normal flora of every individual is not same and depends on the oral hygiene. The prevalence and isolation of bacteria from the oral cavity of diabetic individuals was studied. Staphylococcus aureus and Streptococcus species were the predominant micro flora in this study.

Radharani S.,Sree Narayana Guru College | Valarmathi M.L.,Government College of Technology, Coimbatore
2014 International Conference on Electronics and Communication Systems, ICECS 2014 | Year: 2014

This paper proposes a content based color watermarking scheme based on block SVD and Arnold Transformation [1]. The main intention of watermarking system is to meet two conflicting objectives. They are robustness and transparency. DWT is used as a feature (Content based Watermark) to embed it in the host image. The watermark's pixel is embedded into the maximum singular value bit of each block obtained from the block SVD transformation of host image in each RGB channel. To increase the security, Arnold Transformation is used to watermark scrambling pretreatment. Experimental result shows the robustness of this scheme against common image processing operations such as JPEG compression, noise, rotation, rescaling, etc.., © 2014 IEEE.

Priya N.C.,Bharathiar University | Saravana Kumari P.,Sree Narayana Guru College
International Journal of Pharma and Bio Sciences | Year: 2016

The present investigation deals with the identification of phytochemical compounds present in chloroform and methanol extract of Piper longum and P. nigrum. It showed the presence of phytochemical constituents like tannins, terpenoids, and phenolic compounds, alkaloids and flavonoids. The total phenolic content was determined using the Foin-Ciocalteu assay and total flavonoids by the Aluminium chloride colorimetric assay. Percentage of phenol in mg equivalence of gallic acid of both the peppers in chloroform and methanol extract was same and the percentage of flavonoids in mg equivalence of Quercetine was high in both pepper species. In order to find out the chemical compounds GC-MS analysis was done. It showed the presence of 10-15 volatile compounds and it gave an integrated percentage of many compounds. The black pepper in chloroform contains 15 components, out of that highest integrated percentage of Aspartic acid were present. In the case of long pepper in chloroform extracts gave 14 components, out of that the highest integrated percentage of Micosporine and Graveoline were present. However further studies are focussed towards the importance of these compounds to prevent diseases.

Rafiqkhan M.,Sree Narayana Guru College | Viswambharan V.,Sree Narayana Guru College
International Journal of Pharma and Bio Sciences | Year: 2015

Knowledge of herbs has been handed down from generation to generation for thousands of years. Herbal drugs constitute a major part in all traditional systems of medicines. Plants above all other agents have been used for medicine from time immemorial because they have fitted the immediate personal need and are easily accessible and inexpensive. The medicinal plants find application in pharmaceutical, cosmetic, agricultural and food industry. In last few decades, Syzyium cumini is extensively studied for its medicinal properties by advanced scientific techniques and a variety of bioactive compounds have been isolated from the different parts of the plant and were analysed pharmacologically. In our present investigation, pharmacognostic profile and phytochemical screening of Syzyium cumini bark has been evaluated for the presence of bioactive compounds. The study revealed the presence of alkaloids, flavonoids, terpenoids, phenolic compounds, sterols, carbohydrates, glycosides and tannins. The results suggest that methanolic extract of Syzyium cumini bark has promising therapeutic potential, its pharmacological properties which if properly harness can be used in the management of various diseases and can serve as a base for the development of novel potent drug in ethomedicine.

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