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Prakashiny,Sree Balaji Medical College Hospital | Ganapathy H.,Sree Balaji Medical College Hospital
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2014

Necrobiosis lipoidica is a non-infectious granulomatous disease of unknown etiology and pathogenesis. It is more commonly seen in young adults and early middle aged individual. It is often associated with diabetics and typified by indurated plaques of the shin. Herein, we report a case of necrobiosis lipoidica in a 62 year old non-diabetic female who presented with the complaints of pain and swelling over right knee joint for 3 weeks duration. On examination there was diffuse edema of right lower limb and pigmentation with papule in the right knee joint. Skin biopsy taken from the papule and sent for histopathological examination. Histopathology showed a granulomatous dermatitis, pointing towards necrobiosis lipoidica. Special stain showed Acid Fast Bacilli negative. Histopathology plays a major role in the diagnosis of this rare disorder, besides clinical history.


Jayakumari S.,Bharath University | Prabhu K.,Sree Balaji Medical College & Hospital | Johnson W.M.S.,Sree Balaji Medical College & Hospital | Kalaiselvi V.S.,Sree Balaji Medical College & Hospital
International Journal of Pharmaceutical Sciences Review and Research | Year: 2016

Menstrual cycle function was closely associated with a women’s ability to become pregnant. Various studies explain the possible relationship between menstrual cycle pattern and other reproductive outcome. Based on this background this study was designed to know the menstrual cycle pattern in adolescent girls and the same in their mother. The aim of the study is to assess the menstrual cycle pattern in relation to food habit, BMI and same as in their mothers. 185 adolescent girls (aged 17-22 years) and their parents (34-55) were included in this study. Age at menarche, menstrual cycle pattern, and religion and food pattern were asked as questioner. Height and Weight were measured. Body mass index were calculated by using (BMI; kg m) as an index relative weight. In 87.02% of adolescent girls and 84.86% mothers cycles were regular. Only a few cases both the mothers and daughters had irregular cyclical. The irregular cycle pattern in adolescent girls correlated with increased BMI. Menstrual cycle pattern is associated with the nutritional status and life style modification. Future research could build on this study by associations between parent and daughters cycle by their physical activity. © 2016, Global Research Online. All rights reserved.


Prakashiny,Sree Balaji Medical College Hospital | Parijatham B.O.,Sree Balaji Medical College Hospital | Ganapathy H.,Sree Balaji Medical College Hospital
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2015

The most common type of lesions in the ovary are the cysts and the tumors. Majority of the ovarian cysts are benign with few cases being malignant. This is a retrospective study of all ovarian lesions in the department of Pathology, SBMCH, Chennai for a period of 1 year from August 2012 to September 2013. The specimens were received in 10% formalin from the obstetrics and gynaecological department of SBMCH. The specimen was processed in the histopathology lab and routine Haemotoxylin & eosin staining done. A total of 80 cases were studied during this one year period. Among the 80 cases, cystic lesions accounted for 22.5%,benign ovarian tumor accounted for a majority of 72.5% and malignant tumor for 3.75%. 1 case of borderline seromucinous tumor was reported. The most common type of ovarian tumor was simple serous cystadenoma (42%) followed by mature cystic teratoma (12.5%).2 cases of benign mucinous cystadenoma reported.3 cases of serous papillary cystadenocarcinoma were reported.


Lokeshwari V.,Sree Balaji Medical College Hospital | Hemalatha G.,Sree Balaji Medical College Hospital | Parijatham B.O.,Sree Balaji Medical College Hospital
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2015

65/F came with c/o swelling in the left breast for 6months, on palpation - single nodule felt beneath the nipple and areola. Aspirated blood stained material from the swelling and reported as carcinoma left breast. Mastectomy was done and the specimen was sent for histopathological examination to department of pathology, SBMCH and reported as Ductal carcinoma insitu with microinvasion. DCIS accounts for 25% of all breast carcinomas while DCIS with microinvasion accounts 5% - 10% only. Most commonly occurs during 6th decade. Overall prognosis for microinvasive ductal carcinoma is very good.


PubMed | Sree Balaji Medical College & Hospital
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2013

A 25-year-old male was seen with complaints of itchy skin lesions over left thigh. On examination multiple annular scaly plaques with wavy borders, peripheral papules and central clearing was seen. Closer examination revealed multiple forked tracts with excoriated papules. A diagnosis of cutaneous larva migrans was made and the patient treated using T.Albendazole 400 mg twice daily for 7 days which resulted in complete clinical cure.


PubMed | Bharath University and Sree Balaji Medical College & Hospital
Type: Journal Article | Journal: Diabetes & metabolic syndrome | Year: 2016

Metabolic syndrome has a silent but a fatal course. So, if we are able to identify the subjects in the early course of the disease then we will be able to prevent them from fatal complications later.To study the lipid status among euglycemic offspring of diabetic parents by appropriately matching for sex, and age in controls.It is a case control study involving 52 subjects and 25 controls done in a tertiary care center in Chennai.Using inclusion and exclusion criteria 52 euglycemic offspring as subjects and 25 controls were taken. Serum high density lipoprotein (HDL), serum triglycerides, blood pressure and waist circumference we obtained. The results were tabulated and studied.Student t test was employed.Siblings of diabetic parents had lower levels of serum HDL. Odds ratio showed that offsprings of diabetic parents had the odds of having low HDL 4.67 times when compared to the controls with a confidence interval of 1.6001-13.6563, P value of 0.0048. The other parameters did not show any gross variation. Siblings of diabetic fathers had a more deranged profile than the siblings of diabetic mothers.There is significant association between parental diabetic status and dyslipidemia. If they are detected early then progress to complications can be delayed.


PubMed | Sree Balaji Medical College & Hospital
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2013

Lymphangiomas are congenital lesions of the lymphatic system which are most commonly found in the head and neck, with over 90 % of lesions manifesting in children who are less than 2years of age. Haemolymphangiomas are rare variant of lymphangioma, with the presence of red blood cells within the lymphatic channels. Laryngeal sites are usually in continuity with foci of disease in the neck. In general, symptoms are non-specific and they vary with the site and size of the mass. Usually, they occur before 2 years of age. Isolated cases of lymphangiomas with involvement of epiglottis are rare and only a few cases have been reported so far. We are reporting the case of a six-year-old girl who presented with a mass in the epiglottis.


PubMed | Sree Balaji Medical College & Hospital
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2014

Prostatism is a common malady in the geriatric age group. Benign prostatic hyperplasia and Carcinoma of the prostate are increasingly frequent with advancing age. The aim of the present study is to study the spectrum of prostatic lesions among the biopsies received in a rural hospital.One hundred and six cases of prostatic biopsies received in the Department of Pathology, Rajah Muthiah Medical College and Hospital - Annamalai University were included in the present study. There were 44 needle biopsies and 62 TURP specimens. All the specimens were fixed in 10% neutral buffered formalin and 5 sections were stained with Hematoxylin and Eosin stain (H & E stain). Relevant clinical data including age, the presenting complaints and S.PSA values in suspected cases of carcinoma prostate were recorded.Among the 106 biopsies received, 79 (74.52%) cases were of Benign prostatic hyperplasia, two cases (1.89%) were Prostatic intraepithelial neoplasia and 25 cases (23.58%) were Carcinoma of Prostate. Prostatitis was the most common associated lesion in cases of benign prostatic hyperplasia presenting in 25.31% patients. Among the Carcinoma patients, 20 cases (80%) were of Adenocarcinoma of prostate and 5 cases (20%) were Small cell carcinoma of prostate. Both Benign prostatic hyperplasia and Carcinoma prostate were common in the seventh decade. Most common clinical presentation was difficulty in micturition. Most common histological type of Carcinoma prostate was Adenocarcinoma. Serum PSA estimation was done in 49 cases of prostate biopsies. Elevations of serum PSA levels were noted in both BPH and Carcinoma prostate patients.Eight cases of BPH, had serum PSA values in the range of 0-4ng/ml. Six cases of Carcinoma prostate ,had serum PSA values in the range of >80 ng/ml.Benign prostatic hyperplasia is the most commonly encountered prostatic lesion. Although, investigations like transrectal ultrasonogram and serum PSA estimation aids in diagnosis, a definitive diagnosis of benign and malignant lesions of prostate can be made by histopathological study of prostatic biopsies.


PubMed | Sree Balaji Medical College & Hospital and Bharath University
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2014

Over the past decade, medical schools have made new efforts to provide accurate, reliable, and timely assessments of the competence of trainees. All methods of assessment have strengths and intrinsic flaws. Written examination questions forms an important item in knowledge assessment and are typically classified according to whether they are open-ended or multiple choices. At present questions are prepared casually just before the examination and are not put through any quality check to correct any possible mistakes or ambiguity in the questions. This may lead to confusion or wrong understanding of the questions by the students which will be reflected in their answers as well. Question Vetting is the process when an expert person examines or evaluates and edits questions to make it free of any mistakes. The importance of vetting and re-vetting of examination questions cannot be overstated in the present scenario of medical education. There is a prescribed structure and protocol of question setting and vetting for examinations in medical education programmes. The areas that need to be examined during question vetting are for technical accuracy, content level and language aspects. The use of the prescribed structure and protocol of question vetting ensures a consistently high standard of question presentation during examinations which will help the students to understand the questions better and to answer them correctly. This article is intended to highlight the importance of introducing question vetting in our medical education scenario in order to improve the quality of assessment of medical students.


PubMed | Sree Balaji Medical College & Hospital
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2013

Welding fumes are considered as a risk factor for pulmonary diseases and a periodic spirometry is essential to evaluate the lung function of the welders. The Red Cell Distribution Width (RDW) is a red cell measurement which is provided by automated haematology analyzers. It reflects the range of the red cell sizes which are measured within a sample. Few studies have shown a relationship between the RDW values and the changes in the spirometry.This study was aimed at correlating the RDW% and the spirometry FEV1/FVC ratio (%) among automobile welders (cases). Further, we have analyzed the effect of smoking on the FEV1/FVC ratio% and the RDW% in the cases.A cross sectional study was done on 50 welders and 50 non-welding office workers (controls) who were working in an automobile industry on the outskirts of Chennai, india. All the cases were arc welders and the controls were from the same production unit, who had never worked as welders. This study was conducted during the period from March 2012 to May 2012.The demographic data, smoking habits, work history and the respiratory symptoms were gathered by using a standard self -administered questionnaire. A complete haemogram study was done and pulmonary function tests were performed for both the cases and the controls. All the cases and the controls were examined in the hospital outpatients room and subsequently, their blood samples were collected. The pulmonary function tests were conducted in the spirometry room in the hospital. The statistical analysis was done using the SPSS, version 15.0.A statistically significant inverse correlation was found between the RDW% and the FEV1/FVC ratio% in the cases.RDW can be used as a biomarker to identify the pulmonary compromise in automobile welders.

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