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Dauphin Island, AL, United States

Spring Hill College is a private, Roman Catholic Jesuit liberal arts college in the Spring Hill neighborhood of Mobile, Alabama, United States. It was founded in 1830 by Most Rev. Michael Portier, Bishop of Mobile. It was the first Catholic college in the South, fifth oldest Catholic college in the United States, and third oldest of the 28 member Association of Jesuit Colleges and Universities. It is accredited by the Commission on Colleges of the Southern Association of Colleges and Schools. In 2010, U.S. News & World Report reported that Spring Hill College ranked 14th among the top colleges in the South offering both bachelor's and master's level degreesThe Spring Hill academic calendar is divided into two semesters, a fall semester of 15 weeks beginning at the end of August and ending before Christmas, and a spring semester of 15 weeks beginning in early January and ending in early May. There are May and June mini-sessions, and summer school during June and July. Wikipedia.

Mutchnick M.G.,Spring Hill College | Williams J.M.,Drexel University
Applied Neuropsychology | Year: 2012

The present study examined the relationship of extra-test anxiety to memory test performance among patients undergoing cardiopulmonary bypass (N=47) and back surgery (N=24). These patients were chosen because they are often anxious before surgery and thus serve as a model of extra-test anxiety. This examination is important in neuropsychology because anxiety may serve as an extraneous factor compromising the validity of attention and memory scores. Anxiety level, determined from self-report and experimenter ratings, and memory performance, as measured by the Memory Assessment Scales and memory self-report, were assessed 1 to 2 days presurgery and approximately 6 weeks post surgery. The study further examined whether anxiety's influence on test performance is mediated by an impulsive cognitive style, as indicated by the Matching Familiar Figures Test. Multivariate analysis of variance (MANOVA) revealed no significant change in state anxiety during the testing interval. MANOVA did reveal significant differences between the two surgery groups on anxiety, and younger patients demonstrated greater anxiety about their upcoming surgery. An examination of the intercorrelations of anxiety and memory scores revealed that they do not share variance and are essentially unrelated. Although the subjects were moderately anxious about the upcoming surgery, this did not apparently influence their performance on memory tests. Copyright © Taylor and Francis Group, LLC. Source

Holbert B.,Spring Hill College | Huber M.,University of Texas at Arlington
Universal Access in the Information Society | Year: 2011

The human-computer interface remains a mostly visual environment with little or no haptic interaction. While haptics is finding inroads in specialized areas such as surgery, gaming, and robotics, there has been little work to bring haptics to the computer desktop, which is largely dominated today by the GUI/mouse relationship. The mouse as an input device, however, poses many challenges for users with physical disabilities, and it is believed that a haptically enhanced interface could have significant impact assisting in target selection. This paper presents a study intended to evaluate haptic effects used with a force feedback mouse on a computer desktop and a prediction algorithm designed to focus those effects on the desired target. Results of the experiment were partially successful and indicated future directions for improvement. The paper introduces the proposed framework and presents experimental results from targeting tasks using differing haptic effects with a group of physically disabled users. © 2010 Springer-Verlag. Source

Flanagan T.W.,University of Mississippi Medical Center | Files J.K.,Clinton High School | Files J.K.,Spring Hill College | Casano K.R.,Saint Andrews Episcopal School | And 2 more authors.
Biology Open | Year: 2016

Mammals express six major somatic linker histone subtypes, all of which display dynamic binding to chromatin, characterized by transient binding at a given location followed by rapid translocation to a new site. Using photobleaching techniques, we systematically measured the exchange rate of all six mouse H1 subtypes to determine their relative chromatin-binding affinity. Two subtypes, H1.1 and H1.2, display binding affinities that are significantly lower than all other subtypes. Using in vitro mutagenesis, the differences in chromatin-binding affinities between H1.1 (lower binding affinity) and H1.5 (higher binding affinity) were mapped to a single amino acid polymorphism near the junction of the globular and C-terminal domains. Overexpression of H1.5 in density arrested fibroblasts did not affect cell cycle progression after release. By contrast, overexpression of H1.1 resulted in a more rapid progression through G1/S relative to control cells. These results provide structural insights into the proposed functional significance of linker histone heterogeneity. © 2016. Published by The Company of Biologists Ltd. Source

Qin X.,Vanderbilt University | Byrne M.,Spring Hill College | Xu Y.,Vanderbilt University | Mori T.,Vanderbilt University | Johnson C.H.,Vanderbilt University
PLoS Biology | Year: 2010

Cyanobacteria are the only model circadian clock system in which a circadian oscillator can be reconstituted in vitro. The underlying circadian mechanism appears to comprise two subcomponents: a post-translational oscillator (PTO) and a transcriptional/translational feedback loop (TTFL). The PTO and TTFL have been hypothesized to operate as dual oscillator systems in cyanobacteria. However, we find that they have a definite hierarchical interdependency-the PTO is the core pacemaker while the TTFL is a slave oscillator that quickly damps when the PTO stops. By analysis of overexpression experiments and mutant clock proteins, we find that the circadian system is dependent upon the PTO and that suppression of the PTO leads to damped TTFL-based oscillations whose temperature compensation is not stable under different metabolic conditions. Mathematical modeling indicates that the experimental data are compatible with a core PTO driving the TTFL; the combined PTO/TTFL system is resilient to noise. Moreover, the modeling indicates a mechanism by which the TTFL can feed into the PTO such that new synthesis of clock proteins can phase-shift or entrain the core PTO pacemaker. This prediction was experimentally tested and confirmed by entraining the in vivo circadian system with cycles of new clock protein synthesis that modulate the phosphorylation status of the clock proteins in the PTO. In cyanobacteria, the PTO is the self-sustained core pacemaker that can operate independently of the TTFL, but the TTFL damps when the phosphorylation status of the PTO is clamped. However, the TTFL can provide entraining input into the PTO. This study is the first to our knowledge to experimentally and theoretically investigate the dynamics of a circadian clock in which a PTO is coupled to a TTFL. These results have important implications for eukaryotic clock systems in that they can explain how a TTFL could appear to be a core circadian clockwork when in fact the true pacemaker is an embedded biochemical oscillator. © 2010 Qin et al. Source

De Rooy S.L.,Louisiana State University | El-Zahab B.,Louisiana State University | El-Zahab B.,Massachusetts Institute of Technology | Li M.,Louisiana State University | And 5 more authors.
Chemical Communications | Year: 2011

Herein we report the synthesis of a fluorescent organic salt through anion exchange and the subsequent fabrication of 1D-nanostructures via a facile templating method. © 2011 The Royal Society of Chemistry. Source

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