Iskandar M.E.,University of California at Riverside |
Aslani A.,Spire Inc |
Liu H.,University of California at Riverside
Journal of Biomedical Materials Research - Part A | Year: 2013
Magnesium (Mg) alloys, a novel class of degradable, metallic biomaterials, have attracted growing interest as a promising alternative for medical implant and device applications due to their advantageous mechanical and biological properties. Although its biodegradability is an attractive property, rapid degradation of Mg in the physiological environments imposes a major obstacle that limits the translation of Mg-based implants to clinical applications. Therefore, the objective of this study was to develop a nanostructured hydroxyapatite (nHA) coating on polished Mg substrates to mediate the rapid degradation of Mg while improving its integration with bone tissue for orthopedic applications. The nHA coatings were deposited on polished Mg using the patented transonic particle acceleration (Spire Biomedical) process. Surface morphology, elemental compositions, and crystal structures were characterized using scanning electron microscopy, energy dispersive X-ray spectroscopy, and X-ray diffraction (XRD) analysis, respectively. The degradation of nHA-coated and non-coated Mg samples was investigated by incubating the samples in phosphate buffered saline and revised simulated body fluid, under standard cell culture conditions. Rat bone marrow stromal cells (BMSCs) were harvested and cultured with nHA-coated and non-coated Mg samples to determine cytocompatibility. The degradation results suggested that the nHA coatings decreased Mg degradation. Improved BMSC adhesion was observed on the surfaces of the nHA-coated and non-coated Mg samples, in comparison with the cells on the culture plate surrounding the Mg samples. In conclusion, nHA coatings showed promise for improving the biodegradation and cytocompatibility properties of Mg-based orthopedic implants and should be further studied. Copyright © 2013 Wiley Periodicals, Inc. Source
Spire Inc | Date: 2014-05-30
The present invention provides a system that provides and extends wireless RF signals to any distance location beyond the normal transmission/broadcast of cellular tower utilizing a existing network. The system provides wireless communication carried by wire lines for communication and testing between remote locations in real-time.
Spire Inc | Date: 2013-03-15
In one embodiment, the present invention includes a lighting system. The lighting system comprises a light fixture. The light fixture includes a plurality of light emitting diode (LED) strings and a housing. The plurality of LED strings are electrically coupled in a low voltage configuration. The housing has the plurality of LED strings disposed in the direction of a longitudinal axis of the housing and includes a first and second member. The first member protrudes from a first end of the housing and has a first set of conductive elements electrically coupled across the plurality of LED strings. The second member protrudes from a second end of the housing and has a second set of conductive elements electrically coupled across the plurality of LED strings. The first and second members are complimentary to provide mechanical and electrical coupling between the light fixture and other fixtures without external wiring.
Spire Inc | Date: 2014-02-07
A method and system can generate video content from a video. The method and system can include generating audio files and image files from the video, distributing the audio files and the image files across a plurality of processors and processing the audio files and the image files in parallel. The audio files associated with the video to text and the image files associated with the video to video content can be converted. The text and the video content can be cross-referenced with the video.
Spire Inc | Date: 2011-06-03
In one embodiment, the present invention includes an apparatus for contacting a plurality of contact locations of a semiconductor device. The apparatus includes a housing, a support member, a plurality of probe members, and an adhesive substance. The housing has a plurality of apertures that provides a low leakage pathway for high frequency signals to reach the semiconductor device through the plurality of probe members. The plurality of probe members are aligned on the support member and the adhesive substance secures the plurality of probe members to the supporting member. The housing, supporting member, and adhesive substance match in thermal expansion to reduce the error in alignment between the plurality of contact locations and the plurality of probe members over a temperature variance.