Sparrow Hospital

Lansing, MI, United States

Sparrow Hospital

Lansing, MI, United States
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DUARTE, CA--(Marketwired - May 25, 2017) - Prolacta Bioscience®, the pioneer in human milk-based neonatal nutritional products for premature infants, announced today that it passed the halfway point in a clinical trial evaluating the effect of adding Prolact CR®, a caloric fortifier made from 100 percent human milk cream, to an exclusive human milk-based diet (EHMD)1 for very low birth weight (VLBW) premature infants. The study is evaluating the length of stay and incidence of bronchopulmonary dysplasia (BPD) and has enrolled 127 of the 210 participants weighing between 500 and 1,250g (1 lb 1 oz to 2 lbs 12 oz). The randomized controlled study is evaluating whether adding the human milk cream-based caloric fortifier can decrease the length of hospital stay and reduce BPD, a form of debilitating chronic lung disease not uncommon in VLBW babies. The milk cream caloric fortifier is added as a supplement to an EHMD, which includes the use of 100 percent human milk-based fortifier Prolact+ H2MF®, and is the recommended diet for VLBW infants. "Due to the increased energy and macronutrient requirements of VLBW infants in general, and those with BPD in particular, unfortified human milk does not meet their nutritional needs," said Amy Hair, M.D., lead investigator, Assistant Professor of Pediatrics at Baylor College of Medicine, and the Director of Neonatal Nutrition at Texas Children's Hospital. "VLBW infants require 20 to 40 percent more calories than their age-matched counterparts. These infants also are at higher risk for postnatal growth failure due to disruptions in their feeding regimens. An earlier randomized clinical trial looking at growth suggested that Prolact CR® reduced the incidence and severity of BPD in the group receiving additional nutrients provided from fat." The study, "A Randomized Trial of the Use of Human Milk Cream to Decrease Length of Stay in Extremely Premature Infants," is currently being conducted at Akron Children's Hospital at Boardman, Boardman, Ohio (Linda Cooper, M.D.); Innsbruck Medical University, Innsbruck, Austria (Ursula Kiechl-Kohlendorfer, M.D.); Michigan State University-Sparrow Hospital, Lansing, Mich. (Padmani Karna, M.D.); University of Texas Health Science Center at San Antonio, San Antonio, Texas (Cynthia Blanco, M.D.); Winnie Palmer Hospital for Women & Babies, Orlando, Fla. (Jose Perez, M.D.); Wasatch Neonatal LC, Orem, Utah (Dale Gerstmann, M.D.); St. Joseph's Women's Hospital, Tampa, Fla. (Jenelle Ferry, M.D.); St. John Medical Center, Tulsa, Okla. (Craig Anderson, D.O.); Cook Children's Medical Center, Fort Worth, Texas (David Riley, M.D.); St. Louis Children's Hospital, St. Louis, Mo. (Stephanie Attarian, M.D.); The University of Oklahoma Health Sciences Center, Oklahoma City, Okla. (Andrea Willeitner, M.D.); and Texas Tech University Health Sciences Center El Paso, El Paso, Texas (Lewis Rubin, M.D.). "This clinical trial is the result of secondary findings that were observed in an earlier trial, and underscores the need for continued study of the unique properties in human milk," said Scott Elster, CEO of Prolacta. "We look forward to seeing how Prolact CR® affects lengths of stay and BPD with the hope of uncovering new therapeutic benefits for this fragile patient population." This new clinical trial seeks to verify observations on length of stay and BPD with the use of Prolact CR® from a prior multi-center, randomized trial ("Premature Infants 750-1,250g Birth Weight Supplemented with a Novel Human Milk-Derived Cream are Discharged Sooner," published in Breastfeeding Medicine in 2016). This analysis found that infants who received Prolact CR® were discharged, on average, 12 days earlier than those who did not receive the cream supplement. In the initial trial, infants who developed BPD may have derived an even greater benefit, a finding which prompted this new study. About Prolacta Bioscience Prolacta Bioscience, Inc. is a privately-held life sciences company dedicated to Advancing the Science of Human Milk®. The company pioneered the development of human milk-based neonatal nutritional products to meet the needs of critically ill, premature infants in the neonatal intensive care unit (NICU). Prolacta leads the industry in the quality and safety of nutritional products made from donor breast milk, and operates the first and only pharmaceutical-grade manufacturing facility for the processing of human milk. 1 An EHMD is when 100% percent of the protein, fat and carbohydrates in an infant's intake are derived solely from human milk.


News Article | October 28, 2016
Site: www.prweb.com

Dr. Ahmed Sufyan is proud to report his recent educational talks given at various medical facilities throughout the state. This well-known and respected facial plastic surgeon and ENT has given three talks most recently. All three community outreach seminars focused on topics that helped people understand more about facial plastic surgery and ENT procedures. The talks were geared toward patients as well as plastic surgery and ENT residents. Dr. Sufyan offered the first of his East Lansing-area outreach seminars on April 29, 2016 at McLaren Hospital. This talk discussed topics relating to nasal airway obstruction, nasal allergies, and nasal surgery. He offered another educational seminar on August 9, 2016 at the same hospital. This talk focused primarily on facial reconstruction. Dr. Sufyan's last educational outreach seminar was offered on September 13, 2016 at Sparrow Hospital. During this talk, he spoke about the management of facial trauma. Dr. Sufyan's audience during this seminar consisted of emergency room doctors and surgical residents. Dr. Sufyan brings with him years of expertise and training accrued during his collegiate and post-graduate medical careers. He graduated in Summa Cum Laude in the top one percent from Wayne University with a Bachelor's degree in Biological Sciences. During his time at Wayne University, he was the recipient of a presidential scholarship. He continued his medical training at Indiana University School of Medicine. Completing a residency in Otolaryngology-Head and Neck Surgery, during which he was drawn to the facial plastic surgeon specialty, Dr. Sufyan was one of two physicians who graduated with both research and academic honors. He also achieved the top score in the national specialty training examination. After he completed his residency, Dr. Sufyan then went on to train under the tutelage of current American Academy of Facial Plastic and Reconstructive Surgery president Dr. Edwin Williams, who is recognized as an international leader and foremost expert in facial plastic surgery. While participating in this highly sought after fellowship program, Dr. Sufyan developed his private practice that offers a full range of cosmetic and reconstructive procedures. When he is not offering community outreach seminars or treating patients, Dr. Sufyan likes to volunteer his time in New York where he helps to foster the facial plastic surgery skills and knowledge of Otolaryngology residents. He is a lifelong Michigan resident, having been born and raised in Deerborn, and is also a proud member of the American Academy of Facial Plastic and Reconstructive Surgery, Inc. He likewise garners favorable reviews from his patients. One of his patients, Bob from Charlotte, MI, offers a testimonial in which he says Dr. Sufyan is “very polite and knowledgeable.” To learn more about Dy. Sufyan's upcoming lectures please visit eastlansingplasticsurgery.com or contact the practice at 1500 Abbot Rd. Suite #400 in East Lansing by calling (517) 332-0100.


Centor R.M.,University of Alabama at Birmingham | Atkinson T.P.,Birmingham Childrens Hospital | Ratliff A.E.,Diagnostic Mycoplasma Laboratory | Xiao L.,Diagnostic Mycoplasma Laboratory | And 7 more authors.
Annals of Internal Medicine | Year: 2015

Background: Pharyngitis guidelines focus solely on group A β-hemolytic streptococcal infection. European data suggest that in patients aged 15 to 30 years, Fusobacterium necrophorum causes at least 10% of cases of pharyngitis; however, few U.S. data exist. Objective: To estimate the prevalence of F. necrophorum; Mycoplasma pneumoniae; and group A and C/G β-hemolytic streptococcal pharyngitis and to determine whether F. necrophorum pharyngitis clinically resembles group A β-hemolytic streptococcal pharyngitis. Design: Cross-sectional. Setting: University student health clinic. Patients: 312 students aged 15 to 30 years presenting to a student health clinic with an acute sore throat and 180 asymptomatic students. Measurements: Polymerase chain reaction testing from throat swabs to detect 4 species of bacteria and signs and symptoms used to calculate the Centor score. Results: Fusobacterium necrophorum was detected in 20.5% of patients and 9.4% of asymptomatic students. Group A β-hemolytic streptococcus was detected in 10.3% of patients and 1.1% of asymptomatic students. Group C/G β-hemolytic streptococcus was detected in 9.0% of patients and 3.9% of asymptomatic students. Mycoplasma pneumoniae was detected in 1.9% of patients and 0 asymptomatic students. Infection rates with F. necrophorum, group A streptococcus, and group C/G streptococcus increased with higher Centor scores (P < 0.001). Limitations: The study focused on a limited age group and took place at a single institution. Asymptomatic students-rather than seasonal control participants-and a convenience sample were used. Conclusion: Fusobacterium necrophorum-positive pharyngitis occurs more frequently than group A β-hemolytic streptococcal- positive pharyngitis in a student population, and F. necrophorum- positive pharyngitis clinically resembles streptococcal pharyngitis. © 2015 American College of Physicians.


Werth S.L.,Sparrow Hospital | Schutte D.L.,Wayne State University | Stommel M.,Michigan State University
Journal of Wound, Ostomy and Continence Nursing | Year: 2014

PURPOSE: The purpose of this study was to investigate what specifi c ostomy self-care educational content is considered the most useful by the new ostomy patient after discharge. DESIGN: A cross-sectional, correlational design was used to address study aims. SUBJECTS AND SETTING: The sample comprised 33 men and 27 women with a mean age of 55.58 ± 15.56 (mean ± SD) years, range 27 to 79 years old. The study setting was a 587-bed teaching hospital, level 1 trauma center in the Midwest, with Magnet designation. METHODS: Demographic data were collected during the patients' hospital stay as part of routine care. This information is used for follow-up with all ostomy patients who have surgery in this hospital. All of the participants in this study completed an interview administered by phone or in person. A semistructured interview guide was used to elicit participant perceptions of the usefulness of 4 categories of ostomy care, including (1) ostomy information (ostomy function), (2) activities of daily living (strategies to manage travel, bathing, intimacy, odor), (3) ostomy care (strategies for managing the ostomy), and (4) other informational needs (social support resources). Participants were asked to rate these 4 areas from most useful to least useful, using a 4-point scale. At the end of the interview, participants were asked, "Has there been anything that has happened or event related to your ostomy that your ostomy teaching did not prepare you for?" The interview took place several weeks after surgery or during their readmission visit for surgical ostomy takedown. RESULTS: Sixty-two patients were enrolled into the study, and 60 participants completed the data collection. The sample included 26 (43%) patients with ileostomies, 18 (30%) with colostomies, and 16 (27%) with urostomies. Ninety percent ranked the education category of ostomy self-care as the most useful content, 55% ranked information on resuming activities of daily living as the second most useful category, and 55% ranked general information as third most useful content area. Fifty respondents (83%) ranked ostomy support as the least useful. Nine (15%) of the participants felt unprepared for their fi rst pouch leak, and 2 (3%) reported diffi culty adjusting to the feel of the stool entering the pouch. Two patients would have liked more photos of peristomal skin conditions and how to treat them. CONCLUSIONS: Since the category of ostomy self-care ranked highest, patient teaching for the new ostomy patient should focus on this skill set, including stoma care, how, and when to empty and change the pouch. © 2014 by the Wound, Ostomy and Continence Nurses Society.


The International Association of HealthCare Professionals is pleased to welcome Preeti Jhaveri, MD, FACOG, obstetrician and gynecologist, to their prestigious organization with her upcoming publication in The Leading Physicians of the World. She is a highly-trained and qualified obstetrician and gynecologist with passion for all facets of her work. Dr. Jhaveri has been practicing for more than 8 years and is currently employed at Heartland Health Centers of Chicago, Illinois. She is also on staff at Swedish Covenant Hospital. Dr. Jhaveri obtained her Doctor of Medicine degree from Dr. D.Y. Patil Medical College, of the University of Mumbai in India in 2002. After returning to the United States, Dr. Jhaveri completed a residency at Michigan State University’s Sparrow Hospital, where she served as chief administrative resident, prior to entering private practice. In 2016, she moved from the private practice world to working with the underserved population in Chicago Dr. Jhaveri has special interest in high risk pregnancies, laparoscopy, and vulvar skin diseases. She remains a member of the International Society for the Study of Vulvovaginal Disease, and has earned the coveted title of Fellow of the American College of Obstetricians and Gynecologists. Dr. Jhaveri attributes her success to her passion for improving a woman’s quality of life and her ability to build rapport with her patients. When not serving patients, she enjoys photography, cooking and activities in the great outdoors. She will also be starting a blog in the upcoming year, related to the many mental, emotional, and spiritual trials she sees women face every day. Learn more about Dr. Jhaveri here: https://www.heartlandhealthcenters.org/doctor/jhaveri-preeti/ and by reading her upcoming publication in The Leading Physicians of the World. FindaTopDoc.com is a hub for all things medicine, featuring detailed descriptions of medical professionals across all areas of expertise, and information on thousands of healthcare topics.  Each month, millions of patients use FindaTopDoc to find a doctor nearby and instantly book an appointment online or create a review.  FindaTopDoc.com features each doctor’s full professional biography highlighting their achievements, experience, patient reviews and areas of expertise.  A leading provider of valuable health information that helps empower patient and doctor alike, FindaTopDoc enables readers to live a happier and healthier life.  For more information about FindaTopDoc, visit: http://www.findatopdoc.com


Johnson S.H.,Sparrow Hospital | Theurer P.F.,Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative | Bell G.F.,Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative | Maresca L.,St. Marys of Michigan | And 2 more authors.
Annals of Thoracic Surgery | Year: 2010

Background: The Michigan Society of Thoracic and Cardiovascular Surgeons (MSTCVS) Quality Collaborative is a voluntary, surgeon-directed quality initiative involving all cardiac surgery programs in Michigan. Understanding that internal mammary artery (IMA) use during coronary artery bypass grafting is an important process measure associated with improved outcomes, this analysis reviews our methodology to understand IMA use and increase appropriate IMA use statewide. Methods: Adult cardiac Society of Thoracic Surgeons data were collected at each Michigan site and submitted quarterly to the Duke Clinical Research Institute and the MSTCVS. Seven cardiac surgery programs with IMA use less than 90% in isolated coronary artery bypass grafting were identified as low IMA users. An improvement plan was adopted at the state level and included quarterly monitoring of IMA use, documenting the rationale for IMA exclusion, evidence-based lectures, feedback letters to sites, and physician-led site visits if no improvement was noted. Results: From 2005 through 2008, 29,114 patients underwent coronary artery bypass grafting in Michigan. Internal mammary artery utilization varied widely at the beginning of this investigation, ranging from 66.2% to 98.4%. Seven Michigan programs were identified as low IMA users. Using the MSTCVS Quality Collaborative's process-improvement plan, collectively the seven low IMA users increased IMA grafting from 82.0% to 92.7% (p < 0.0001). Michigan IMA use increased from 91.9% to 95.8% (p < 0.0001) and is now higher than The Society of Thoracic Surgeons' average. Conclusions: The MSTCVS Quality Collaborative identified programs with low IMA use and created an environment to enhance IMA utilization during coronary artery bypass grafting, a significant operative process. These findings illustrate the value of a statewide surgeon-directed quality initiative in improving processes and outcomes for patients. © 2010 The Society of Thoracic Surgeons.


Pastores S.M.,Sloan Kettering Cancer Center | O'Connor M.F.,University of Chicago | Kleinpell R.M.,Rush University Medical Center | Napolitano L.,University of Michigan | And 4 more authors.
Critical Care Medicine | Year: 2011

Objectives: The Accreditation Council for Graduate Medical Education recently released new standards for supervision and duty hours for residency programs. These new standards, which will affect over 100,000 residents, take effect in July 2011. In response to these new guidelines, the Society of Critical Care Medicine convened a task force to develop a white paper on the impact of changes in resident duty hours on the critical care workforce and staffing of intensive care units. PARTICIPANTS:: A multidisciplinary group of professionals with expertise in critical care education and clinical practice. DATA SOURCES AND SYNTHESIS:: Relevant medical literature was accessed through a systematic MEDLINE search and by requesting references from all task force members. Material published by the Accreditation Council for Graduate Medical Education and other specialty organizations was also reviewed. Collaboratively and iteratively, the task force corresponded by electronic mail and held several conference calls to finalize this report. MAIN Results: The new rules mandate that all first-year residents work no more than 16 hrs continuously, preserving the 80-hr limit on the resident workweek and 10-hr period between duty periods. More senior trainees may work a maximum of 24 hrs continuously, with an additional 4 hrs permitted for handoffs. Strategic napping is strongly suggested for trainees working longer shifts. Conclusions: Compliance with the new Accreditation Council for Graduate Medical Education duty-hour standards will compel workflow restructuring in intensive care units, which depend on residents to provide a substantial portion of care. Potential solutions include expanded utilization of nurse practitioners and physician assistants, telemedicine, offering critical care training positions to emergency medicine residents, and partnerships with hospitalists. Additional research will be necessary to evaluate the impact of the new standards on patient safety, continuity of care, resident learning, and staffing in the intensive care unit. © 2011 by the Society of Critical Care Medicine and Lippincott Williams & Wilkins.


Shaw D.,Michigan State University | Cuison R.,Sparrow Hospital | Ito H.,Michigan State University
Current Oncology | Year: 2014

Follicular dendritic cell sarcoma (fdcs) is a rare entity, often presenting a diagnostic challenge for both the pathologist and the clinician. It accounts for only 0.4% of soft-tissue sarcomas, and its underlying causes are largely unknown. Most of these tumours occur in lymph nodes, and extranodal involvement is uncommon. In the gastrointestinal tract, fdcs is extremely rare. Here, we report a case of primary fdcs originating in the stomach. Upon review of the literature, we identified only 2 additional cases of fdcs presenting as a primary stomach tumour. Given the rarity of this tumour in gastrointestinal sites and the lack of consensus on treatment, evaluation of this entity must continue. © 2014 Multimed Inc.


Chang H.T.,Michigan State University | Chang H.T.,Sparrow Hospital | Olson L.K.,Michigan State University | Schwartz K.A.,Michigan State University
Nutrition and Metabolism | Year: 2013

Background: Recent studies in animal models, based on the hypothesis that malignant glioma cells are more dependent on glycolysis for energy generation, have shown promising results using ketogenic diet (KD) therapy as an alternative treatment strategy for malignant glioma, effectively starving glioma cells while providing ketone bodies as an energy source for normal neurons and glial cells. In order to test this treatment strategy in humans, we investigated the relative expression of several key enzymes involved in ketolytic and glycolytic metabolism in human anaplastic glioma (WHO grade III) and glioblastoma (GBM, WHO grade IV). Methods. Immunohistochemistry was performed on formalin fixed paraffin embedded sections from 22 brain biopsies (17 GBM, 3 anaplastic astrocytoma and 2 anaplastic oligoastrocytoma) using antibodies raised against glycolytic and ketolytic enzymes. The glycolytic enzymes included hexokinase-II (HK2) and pyruvate kinase M2 isoform (PKM2). The ketone body metabolic enzymes included: succinyl CoA: 3-oxoacid CoA transferase (OXCT1), 3-hydroxybutyrate dehydrogenase 1 and 2 (BDH1 and BDH2), and acetyl-CoA acetyltransferase 1 (ACAT1). The immunoreactivities were graded using a semi-quantitative scale based on the percentage of positive cells: POS (>20%), LOW (5-20%), and very low (VLOW) (<5%). Focal non-neoplastic "normal" brain tissue within the biopsy specimens served as internal controls. Results: The rate limiting mitochondrial ketolytic enzymes (OXCT1 and BDH1) were either LOW or VLOW, concordantly in 14 of the 17 GBMs and in 1 of 5 anaplastic gliomas, whereas at least one of the glycolytic enzymes was POS in 13 of these 17 GBMs and all 5 anaplastic gliomas. Cytosolic BDH2 and mitochondrial ACTAT1 were, surprisingly, POS in most of these tumors. Conclusion: Our results showing that malignant gliomas have differential expression of ketolytic and glycolytic enzymes are consistent with previous studies that have shown that these are genetically heterogeneous tumors. It seems reasonable to hypothesize that patients with low or very low expression of key ketolytic enzymes in their malignant gliomas may respond better to the KD therapy than those patients with positive expression of these enzymes. Further studies in animal models and/or a large-scale clinical trial would be needed to test this hypothesis. © 2013 Chang et al.; licensee BioMed Central Ltd.


Gupta M.,Michigan State University | Guertin S.,Michigan State University | Guertin S.,Sparrow Hospital | Martin S.,Michigan State University | And 3 more authors.
Pediatrics | Year: 2012

In a 29-day-old premature infant with respiratory syncytial virus (RSV) pneumonia, we have shown an additive effect of high-frequency oscillatory ventilation (HFOV) and continuous inhalation of prostacyclin (iPGI2) with improvement of ventilation and oxygenation. The addition of continuous inhaled iPGI2 to HFOV was beneficial in the treatment of hypoxemic respiratory failure owing to RSV-associated pneumonia. The improvement in alveolar recruitment by increasing lung expansion by HFOV along with less ventilation-perfusion mismatch by iPGI2 appears to be responsible for the synergistic effect and favorable clinical outcome. We conclude that the combined therapy of HFOV and continuous inhaled iPGI2 may be considered in RSV-associated hypoxemic respiratory failure in pediatric patients. Copyright © 2012 by the American Academy of Pediatrics.

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