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Central, SC, United States

Southern Wesleyan University is a four-year and graduate Christian college, with its main campus in Central, South Carolina. The university was founded in 1906 by what is now the Wesleyan Church.The school prepares students for leadership and graduate study in such fields as business, education, religion, music, medicine, law and a variety of civic and social service professions. It offers approximately 35 major areas of study for undergraduates and also offers graduate degrees in the areas of business and education. The university serves approximately 1,900 students. There are more than 600 traditional undergraduates enrolled at the main campus in Central, South Carolina. In addition, undergraduate and graduate programs are offered in a non-traditional, evening format at regional learning centers in Central, Greenville, Columbia, Charleston, North Augusta, Greenwood and Spartanburg. Dr. Todd Voss serves as Southern Wesleyan University's president.The school has 15 intercollegiate athletic teams. In 2007, women's basketball and men's baseball teams won their respective National Christian College Athletic Association national championships. Men's soccer and individual men's golf won NCCAA National Championships in 2013. Wikipedia.


Yang X.,Clemson University | Tietje A.H.,Southern Wesleyan University | Yu X.,Clemson University | Wei Y.,Clemson University
International Journal of Oncology | Year: 2016

Whereas cancer immunotherapy with cytokines in recent research was demonstrated effective in activating immune response against tumor cells, one major obstacle with the use of these cytokines is their severe side effects when delivered systemically at high doses. Another challenge is that advanced tumor cells often evade immunosurveillance of the immune system as well as of the Fas-mediated apoptosis by various mechanisms. We report the design and preliminary evaluation of the antitumor activity of a novel fusion protein-mIL-12/FasTI, consisting of mouse interleukin-12 and the transmembrane and intracellular domains of mouse Fas. The fusion construct (pmIL-12/FasTI) was transfected into mouse lung carcinoma cell line TC-1. Stable cell clones expressing the fusion protein were established as assayed by RT-PCR and immunohistochemistry. ELISA and cell proliferation analyses demonstrated that NK cells were effectively activated by the fusion protein with increased IFN-γ production and cytotoxicity. Enhanced caspase-3 activity of the clones when co-cultured with NK cells indicated that apoptosis was induced through Fas/FasL signaling pathway. The preliminary results suggest a synergized anticancer activity of the fusion protein. It may represent a promising therapeutic agent for cancer treatment. Source


Hedetniemi S.M.,Clemson University | Hedetniemi S.T.,Clemson University | Jiang H.,Clemson University | Kennedy K.E.,Southern Wesleyan University | McRae A.A.,Appalachian State University
Information Processing Letters | Year: 2012

The efficiency of a set S⊆V in a graph G=(V,E), is defined as ε(S)=|{vεV-S:|N(v)∩>S|=1}|; in other words, the efficiency of a set S equals the number of vertices in V-S that are adjacent to exactly one vertex in S. A set S is called optimally efficient if for every vertex vεV-S, ε(S∪{v})≤ε(S), and for every vertex uεS, ε(S-{u})<ε(S). We present a polynomial time self-stabilizing algorithm for finding an optimally efficient set in an arbitrary graph. This algorithm is designed using the distance-2 self-stabilizing model of computation. © 2012 Elsevier B.V. Source


Hedetniemi S.T.,Clemson University | Jacobs D.P.,Clemson University | Kennedy K.E.,Southern Wesleyan University
Computer Journal | Year: 2013

A set S of nodes in a graph G = (V,E) is independent if no two nodes in S are adjacent.We present two types of self-stabilizing algorithms for finding disjoint independent sets R and B. In one type, R is maximal independent in G and B is maximal independent in the induced subgraph G[V - R]. In the second type, R is maximal independent in G[V - B] and B is maximal independent in G[V - R]. Both the central and distributed schedulers are considered.© The Author 2012. Published by Oxford University Press on behalf of The British Computer Society. All rights reserved. Source


Hedetniemi S.M.,Clemson University | Hedetniemi S.T.,Clemson University | Kennedy K.E.,Southern Wesleyan University | McRae A.A.,Appalachian State University
Parallel Processing Letters | Year: 2013

An unfriendly partition is a partition of the vertices of a graph G = (V,E) into two sets, say Red R(V) and Blue B(V), such that every Red vertex has at least as many Blue neighbors as Red neighbors, and every Blue vertex has at least as many Red neighbors as Blue neighbors. We present three polynomial time, self-stabilizing algorithms for finding unfriendly partitions in arbitrary graphs G, or equivalently into two disjoint dominating sets. © 2013 World Scientific Publishing Company. Source


Health-care professionals currently have the right to conscientiously object to any procedure that they deem as morally illicit or that, in their opinion, could harm the patient. However, the right of conscientious refusal in medicine is currently under severe scrutiny. Medical procedures such as abortion and physicianassisted suicide that are not commonly medically indicated, but that can be requested by the patient, represent a type of medical care that is the penultimate expression of patient autonomy. When a health-care provider exercises his or her conscience in a way that denies the patient immediate access to such procedures, many claim that patient autonomy has been oppressed by the religious convictions of the health-care professional. As such, there is a growing opposition to the protection of conscience rights in health care that deserves attention. A common strategy used to defend conscience rights has been to claim that under the United States Bill of Rights, the health-care professional must be allowed to exercise their religious liberties in the context of their profession. This rationale seems to ignite a more intense opposition to conscience rights as it seems to validate the sense that a health-care professional's religious convictions are protected at the cost of patient autonomy. This paper reviews the current status of this debate and proposes a defense of conscience rights in health care that considers both the autonomy of the health-care worker and that of the patient in the context of the patient-physician relationship. © 2012 by the Catholic Medical Association. All rights reserved. Source

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