Chittagong, Bangladesh
Chittagong, Bangladesh

Southern University Bangladesh or is a private university in Chittagong, Bangladesh. Southern was established as an Institute in 1998. Under the Private University Act.The University founded in the year 2003 got approval from Ministry of Education. Southern University is accredited by the University Grants Commission Bangladeshis the highest controlling authority for Government and Non-Government Universities in Bangladesh. Wikipedia.


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PubMed | Federal University of Piauí, Southern University Bangladesh and Federal University of Pernambuco
Type: Journal Article | Journal: Anais da Academia Brasileira de Ciencias | Year: 2015

Croton zehntneri (Euphorbiaceae) is a native aromatic plant from Northeast region of Brazil. The monoterpenoid estragole (ESL) has been isolated by classical chromatographic methods from the essential oil (EO) of C. zehnteneri leaves and characterized by GC-FID and GC-MS, its antimicrobial and cytotoxic potentials being assessed. The analysis of the EO enabled the identification of 100% of the integrated constituents, of which yield was about 1.8%. The main components identified were: eucalyptol, estragole (84.7%) and spathulenol. The dosage of 50 g/disk of ESL presented fairly significant zones of inhibition against Gram-positive bacteria and fungi. The ESL presented toxicity against Artemia salina with LC50 and LC90 of 4,54 and 8,47 g mL-1. However, in tumor inhibition assays (human cells), there were no rewarding inhibition in any of the human cancer cell lines (MCF-7, HEP-2 and NCI-H292).


Costa J.P.,Federal University of Piauí | De Oliveira G.A.L.,Federal University of Piauí | De Almeida A.A.C.,Federal University of Piauí | Islam M.T.,Federal University of Piauí | And 3 more authors.
Brain Research | Year: 2014

Phytol, a branched chain unsaturated alcohol, is particularly interesting because it is an isolated compound from essential oils of different medicinal plants. The aim of this study was to evaluate the anxiolytic-like effects of phytol in animal models to clarify their possible action mechanism. After acute intraperitoneal treatment with phytol at doses of 25, 50 and 75 mg/kg behavioral models of open-field, elevated-plus-maze, rota-rod, light-dark, marble-burying and pentobarbital sleeping time tests were utilized. In open field test, phytol (25, 50 and 75 mg/kg) [p<0.01] increased the number of crossings and rearings. However, the number of groomings [p<0.01] was reduced. Likewise, the number of entries and the time spent in light space were increased [p<0.01] while the number of marble-burying was decreased [p<0.001], in elevated-plus-maze, light-dark and marble-burying tests, respectively. In motor activity test, phytol (75 mg/kg) impaired the rota-rod performance of mice [p<0.01]. In pentobarbital sleeping time test, phytol 75 mg/kg decreased for latency of sleeping and phytol (25, 50 and 75 mg/kg) increased the sleep time when compared to negative control [p<0.05]. All these effects were reversed by pre-treatment with flumazenil (2.5 mg/kg, i.p.), similarly to those observed with diazepam (2 mg/kg, i.p.; positive control) suggesting that the phytol presents mechanism of action by interaction with the GABAergic system. These findings suggest that acute administration of phytol exerts an anxiolytic-like effect on mice. Furthermore, suppose that phytol interacts with GABAA receptor, probably at the receptor subtypes that mediate benzodiazepines effects, to produce sedative and anxiolytic activities. © 2013 Published by Elsevier B.V.


Mahbubur Rahman A.H.M.,Southern University Bangladesh | Murad M.H.,Daffodil International University
Astrophysics and Space Science | Year: 2014

Some new families of electrically charged stellar models of ultra-compact star have been studied. With the help of particular form of one of the metric potentials the Einstein-Maxwell field equations in general relativity have been transformed to a system of ordinary differential equations. The interior matter pressure, energy-density, and the adiabatic sound speed are expressed in terms of simple algebraic functions. The constant parameters involved in the solution have been set so that certain physical criteria satisfied. Based on the analytic model developed in the present work, the values of the relevant physical quantities have been calculated by assuming the estimated masses and radii of some well known potential strange star candidates like X-ray pulsar Her X-1, millisecond X-ray pulsar SAX J 1808.4-3658, and 4U 1820-30. The analytical equations of state of the charged matter distribution may play a significant role in the study of the internal structure of highly compact charged stellar objects in general relativity. © 2014 Springer Science+Business Media Dordrecht.


Islam Md.T.,Federal University of Piauí | Islam Md.T.,Southern University Bangladesh | De Alencar M.V.O.B.,Federal University of Piauí | Da Conceicao Machado K.,Federal University of Piauí | And 3 more authors.
Chemico-Biological Interactions | Year: 2015

This study aims to review phytol (PYT), through published articles, periodicals, magazines and patents, which were retrieved from the PM, SD, WS, SP; DII, WIPO, CIPO, USPTO and INPI databases. Among the 149 articles and 62 patents, 27.52% articles and 87.09% patients were found on the searched topic, PYT and its sources and synthesis and metabolism; then followed by 15.44% and 14.77% articles on PYT in cytotoxicity/cancer/mutagenicity/teratogenicity and PYT in neurological diseases, respectively. In the pharma-medico viewpoint, PYT and its derivatives have been evident to have antimicrobial, cytotoxic, antitumorous, antimutagenic, anti-teratogenic, antibiotic-chemotherapeutic, antidiabetic, lipid lowering, antispasmodic, anticonvulsant, antinociceptive, antioxidant, anti-inflammatory, anxiolytic, antidepressant, immunoadjuvancy, hair growth facilitator, hair fall defense and antidandruff activities. Otherwise, the important biometebolite of PYT is phytanic acid (PA). Evidence shows PA to have cytotoxic, anticancer, antidiabetic, lipid lowering and aniteratogenic activities. In addition, it may be considered as an important biomarker for some diseases such as Refsum's Disease (RD), Sjögren Larsson syndrome (SLS), rhizomelic chondrodysplasia punctata (RZCP), chronic polyneuropathy (CP), Zellweger's disease hyperpipecolic academia (ZDHA) and related diseases. Thus, phytol may be considered as a new drug candidate. © 2015 Elsevier Ireland Ltd.


PubMed | Federal University of Piauí, Southern University Bangladesh and Federal University of Paraiba
Type: | Journal: Chemico-biological interactions | Year: 2015

This study aims to review phytol (PYT), through published articles, periodicals, magazines and patents, which were retrieved from the PM, SD, WS, SP; DII, WIPO, CIPO, USPTO and INPI databases. Among the 149 articles and 62 patents, 27.52% articles and 87.09% patients were found on the searched topic, PYT and its sources and synthesis and metabolism; then followed by 15.44% and 14.77% articles on PYT in cytotoxicity/cancer/mutagenicity/teratogenicity and PYT in neurological diseases, respectively. In the pharma-medico viewpoint, PYT and its derivatives have been evident to have antimicrobial, cytotoxic, antitumorous, antimutagenic, anti-teratogenic, antibiotic-chemotherapeutic, antidiabetic, lipid lowering, antispasmodic, anticonvulsant, antinociceptive, antioxidant, anti-inflammatory, anxiolytic, antidepressant, immunoadjuvancy, hair growth facilitator, hair fall defense and antidandruff activities. Otherwise, the important biometebolite of PYT is phytanic acid (PA). Evidence shows PA to have cytotoxic, anticancer, antidiabetic, lipid lowering and aniteratogenic activities. In addition, it may be considered as an important biomarker for some diseases such as Refsums Disease (RD), Sjgren Larsson syndrome (SLS), rhizomelic chondrodysplasia punctata (RZCP), chronic polyneuropathy (CP), Zellwegers disease hyperpipecolic academia (ZDHA) and related diseases. Thus, phytol may be considered as a new drug candidate.


Ullah H.M.A.,Gyeongsang National University | Zaman S.,North South University | Juhara F.,North South University | Akter L.,North South University | And 3 more authors.
BMC Complementary and Alternative Medicine | Year: 2014

Background: The present study was aimed to investigate the antinociceptive and anti-inflammatory activity of the Curcuma zedoaria (family Zingiberaceae) ethanolic rhizome extract in laboratory using both in vitro and in vivo methods so as to justify its traditional use in the above mentioned pathological conditions. Methods: Phytochemical screening was done to find the presence of various secondary metabolites of the plant. In vivo antinociceptive activity was performed employing the hot plate method, acidic acid induced writhing test and formalin induced writhing test on Swiss albino mice at doses of 250 and 500 mg/kg body weight. Anti-inflammatory activity test was done on Long Evans rats at two different doses (250 and 500 mg/kg body weight) by using carrageenan induced paw edema test. Finally in vitro anti-inflammatory test by protein-denaturation method was followed. Data were analyzed by one-way analysis of variance (ANOVA) and Dunnett's t-test was used as the test of significance. P value <0.05 was considered as the minimum level of significance. Results: Phytochemical screening revealed presence of tannins, saponins, flavonoids, gums & carbohydrates, steroids, alkaloids, reducing sugars and terpenoids in the extract. In the hot plate method, the extract increased the reaction time of heat sensation significantly to 61.99% and 78.22% at the doses of 250 and 500 mg/kg BW respectively. In acetic acid induced writhing test, the percent inhibition of writhing response by the extract was 48.28% and 54.02% at 250 and 500 mg/kg doses respectively (p < 0.001). The extract also significantly inhibited the licking response in both the early phase (64.49%, p < 0.01) and the late phase (62.37%, p < 0.01) in formalin induced writhing test. The extract significantly (p < 0.05, p < 0.01 and p < 0.001) inhibited carrageenan induced inflammatory response in rats in a dose related manner. In in-vitro anti-inflammatory test, the extract significantly inhibited protein denaturation of 77.15, 64.43, 53.04, 36.78 and 23.70% for doses of 500, 400, 300, 200 and 100 μg/mL respectively. Conclusions: The results obtained from the tests indicate that the plant might have one or more secondary metabolite(s) having central and peripheral analgesic and anti-inflammatory activity. © 2014 Ullah et al.; licensee BioMed Central Ltd.


Chowdhury R.H.,National University of Malaysia | Ullah H.,Southern University Bangladesh | Reaz M.B.I.,National University of Malaysia
Journal of Theoretical and Applied Information Technology | Year: 2015

Muscle fatigue is often caused by unhealthy and irregular work practice. It is defined as a long lasting reduction of the ability to contract and it is the condition when produced force is reduced. Faster walking can cause muscle fatigue, which is unhealthy when the level of fatigue is high. There are many mathematical parameters that are suitable to assess the muscle fatigue during gait. Out of these parameters, the amplitude and frequency of the surface EMG signal (sEMG) reflects the more accurate physiological activity in the motor unit during contraction and at rest. In this research, Empirical mode decomposition (EMD) - based filtering process is applied on sEMG signal for realizing the fatiguing contraction during subject walking exercise. The purpose of this research is to evaluate the surface electromyographic parameters (RMS, IAV and AIF) for addressing the effectiveness of the EMD method. In this study, RMS, IAV and AIF values were used as spectral variable, which extensively categorizes the difference between fatigue and normal muscle when using EMD method compared with other different wavelet functions (WFs). Furthermore, the outcome also demonstrates that, amplitude and frequency of EMG signal significantly changes from rest position to maximum contraction position. In this study, we will try to show that by using the EMD method an identification of reliable discrimination between fatigue and non-fatigue muscle is possible. © 2005 - 2015 JATIT & LLS. All rights reserved.


Nayeem G.M.,Southern University Bangladesh | Khan Md.A.R.,Southern University Bangladesh | Mottalib M.A.,Islamic University of Technology
2012 International Conference on Informatics, Electronics and Vision, ICIEV 2012 | Year: 2012

For the last decade or so wireless and mobile communication and its application has been enjoying tremendous attention because of their unique features. More recently, an increasing emphasis has been on the potential of infrastructure less wireless mobile networks that are easy, fast and in-expensive to set up, with the view that such technologies will enable numerous new applications in a wide range of areas. However, security in ILWN is still its primary stage as very little attention has been devoted so far to this topic by the research community. We identify the initial exchange of authentication and key credentials, referred to as pre-authentication, as well as authentication and key exchange as primary security goals. In particular, the problem of authentication has been widely neglected in existing security solutions, even though it is a necessary pre-requisite for other security goals. The Elliptic curve crypto system (ECC) provides more security in less key length which makes is energy efficient. Through a thorough study and implementation we show the scheme provide better security to infrastructure less wireless networks. © 2012 IEEE.


Khan M.A.A.,Southern University Bangladesh | Islam M.T.,Southern University Bangladesh
Journal of Pharmacy and Bioallied Sciences | Year: 2012

Objectives: The aim of the study was to evaluate analgesic and cytotoxic activity of Acorus calamus L., Kigelia pinnata L., Mangifera indica L., Tabernaemontana divaricata L. extracts by using acetic acid-induced writhing method in mice and brine shrimp lethality assay. Materials and Methods: The ethanolic extracts of the plants were obtained by simple maceration method and were subjected to standardization by using pharmacognostical and phytochemical screening methods, which were followed by acetic acid writhing and brine shrimp lethality test methods. Dose selection was made on the basis of acute oral toxicity study (10-1000 mg/kg body weight). Results and Conclusion: In analgesic test, M. indica L. extract produced 28.16% and 22.02% writhing protection at the doses of 250 and 500 mg/kg body weight in mice, respectively. While the T. divaricata L. extract produced 22.02% and 33.93%, K. pinnata L. extract produced 11.55% and 47.29% and A. calamus L. extract produced 15.16% and 54.51% of writhing protection at the same doses. The percent mortality (mean ± SD) was found to be 58.7 ± 25.22, 56.25 ± 22.88, 52.50 ± 24.37, and 61.25 ± 26.66 with M. indica L., T. divaricata L., K. pinnata L., and A. calamus L., respectively. And the LC 50 and LC 90 values were found to be 100 and 300 μg/mL for M. indica L. and that were (200 and 350 μg/mL), (100 and 350 μg/mL) and (50 and 300 μg/mL) for T. divaricata L., K. pinnata L., and A. calamus L., respectively. Thus it can be concluded that bark of M. indica L., leaves of T. divaricata L., bark of K. pinnata L., and roots of A. calamus L. have significant analgesic and cytotoxic activity and can be preferred in the treatment of pain and tumor.


Daiyan G.M.,Southern University Bangladesh | Mottalib M.A.,Islamic University of Technology | Rahman M.M.,Islamic University of Technology
Proceeding of the 15th International Conference on Computer and Information Technology, ICCIT 2012 | Year: 2012

A high performance decision based median filter is proposed for removal of salt and pepper in images. It is an enhanced Adaptive Switching Median filter which initially detects noise pixels iteratively through several phases and replaces the noisy pixels with median value. It calculates median value without considering noisy pixels to improve the performance of median filter for high density noise. Detection of noise is done by expanding the mask until 7×7 to maintain local information extraction. Moreover, the processing pixel is replaced by last processed pixel if the algorithm fails to detect noise free pixel at 7×7. If the noise free median value is not available at 7×7 processing window, the last processed pixel take into consideration if it is noise free. If the last processed pixel is noisy, the algorithm select a window size with 15×15 dimension and calculate the number of 0's and 255's in the processing window. Then replace the processing pixel with 0 or 255 which is more in number in the selected window. Experiment result shows that it can provide very high quality restored images for images that are contaminated by 'salt & pepper' noise, especially when the noise density is large. © 2012 IEEE.

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