Southern Research Institute is a not-for-profit institute that conducts basic and applied research sponsored by both commercial and non-commercial organizations in areas such as Drug Discovery, Drug Development and Engineering and Environmental science. Wikipedia.
Duke University, University of Kansas and Southern Research Institute | Date: 2014-10-15
This invention relates generally to the discovery of a method of inhibiting, preventing or treating bacterial infections. The invention also relates to a method of inhibiting bacterial capsule biogenesis.
Southern Research Institute | Date: 2015-02-24
The present disclosure relates generally to treating or preventing diseases associated with angiogenesis by administering to a patient certain compounds found to inhibit or substantially reduce angiogenesis. Compounds employed according to the present disclosure exhibit good anti-angiogenic activity as well as demonstrate a prophylactic effect for preventing and substantially reducing angiogenesis. Examples of such compounds include Ritanserin, Amiodarone, Terfenadinc, Perphenazine, Bithionol, and Clomipramine.
Southern Research Institute | Date: 2013-10-11
Provided are compounds represented by the formula: with Y, Ri, and R2 being defined in the present disclosure; pharmaceutically acceptable salts thereof, deuterated forms thereof, isomers thereof, solvates thereof, and mixtures thereof. The compounds can be used for treating a patient suffering from a condition capable of treatment with a partial agonist or antagonist of the dopamine D2/D3 receptors and are especially useful for patients suffering from schizophrenia, depressions, neurodegenerative diseases such as Parkinsons, dyskinesias, substance abuse and relapse to substance abuse and addiction to substances such as cocaine, methamphetamine, nicotine and alcohol, glaucoma, cognitive disorders, restless leg syndrome, attention deficit hyperactivity disorders, hyperprolactinemia, autism, motor disturbances such as akathisia, rigor, dystonias as well as various disorders of the urinary tract and other neurologic disorders. Also provided are processes for the preparation of compounds of the present disclosure.
Southern Research Institute and The Uab Research Foundation | Date: 2014-01-14
Cornell University, The Uab Research Foundation and Southern Research Institute | Date: 2015-07-16
A process for inhibiting a mammalian cancerous cell or virally infected cell includes providing a