Birmingham, AL, United States
Birmingham, AL, United States

Southern Research Institute is a not-for-profit institute that conducts basic and applied research sponsored by both commercial and non-commercial organizations in areas such as Drug Discovery, Drug Development and Engineering and Environmental science. Wikipedia.


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Patent
The Uab Research Foundation and Southern Research Institute | Date: 2015-05-21

In one embodiment, a hinged microfracture awl includes a handle, and a shaft that extends through and from the handle, the shaft being pivotally mounted to the handle with a hinge, wherein a distal end of the shaft includes a sharp tip adapted to pierce bone and a proximal end of the shaft includes an impact head adapted to be struck by a striking tool.


Patent
Southern Research Institute | Date: 2016-07-08

In one aspect, the invention relates to pharmaceutical compositions and methods for treating a cancer comprising administration of an EGFR inhibitor and a MEK or MET inhibitor. In various aspects, the methods can comprise determination of increased levels of HGF, e.g., determining if a patient has an increased level of serum HGF. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.


Patent
Southern Research Institute | Date: 2016-04-26

Disclosed herein is a method and apparatus that uses a brine from a well that is used to both generate electricity and recover valuable minerals present in the brine. The method and apparatus uses a hydrophobic membrane to separate water vapor from the brine to concentrate the brine that is then used to recover the minerals.


Patent
Southern Research Institute | Date: 2016-06-07

Nickel based catalyst structures are described herein that include a plurality of metal oxides formed as crystalline phases within the catalyst structures. Each metal oxide of a catalyst structure includes nickel and/or aluminum, where one or more metal oxides includes a nickel aluminum oxide, and the one or more nickel aluminum oxides is greater than 50% by weight of the catalyst structure. The catalyst structures further have surface areas of at least 13 m^(2)/g. The catalyst structures are resistant to high concentrations of sulfur and are effective in reforming operations for converting methane and other light hydrocarbons to hydrogen and one or more other components. For example, the catalyst structures are effective in coal and biomass gasification systems for the forming and cleanup of synthetic gas.


Patent
Southern Research Institute | Date: 2016-04-12

Disclosed herein are a catalyst and method useful in the process of converting sugars to acrylonitrile.


Patent
Southern Research Institute and The Uab Research Foundation | Date: 2016-01-22

A frame for supporting one or more surgical tools during a surgical procedure. The frame is connectable to a surgical table and has at least one transverse support assembly and at least one longitudinal support assembly. Each longitudinal support assembly extends between and is coupled to the first transverse support assembly and either a second transverse support assembly or a support post that is spaced from the first transverse support assembly relative to a longitudinal axis of the table. Each longitudinal support assembly has a shaft and at least one connector that is coupled to the shaft and configured to engage and support a surgical tool. The frame is connectable to the surgical table such that the first and second transverse support assemblies and the at least one longitudinal support assembly are spaced from the surgical table in an upward direction.


Nickel based catalyst structures are described herein that include a plurality of metal oxides formed as crystalline phases within the catalyst structures. Each metal oxide of a catalyst structure includes nickel and/or aluminum, where one or more metal oxides includes a nickel aluminum oxide, and the one or more nickel aluminum oxides is greater than 50% by weight of the crystalline phases within the catalyst structure. The catalyst structures further have specific surface areas of at least 13 m^(2)/g. Mixed nickel aluminates such as the spinel phase, NiAl_(2)O_(4), and NiAl_(10)O_(16) are shown to have a high stability in reforming reactions. The catalyst structures are resistant to high concentrations of sulfur and are effective in reforming operations for converting methane and other light hydrocarbons to hydrogen and one or more other components. For example, the catalyst structures are effective in coal and biomass gasification systems for the forming and cleanup of synthetic gas.


Grant
Agency: National Aeronautics and Space Administration | Branch: | Program: STTR | Phase: Phase I | Award Amount: 124.97K | Year: 2016

GTL?s SNS technology aids in the operation of new or existing structural health monitoring (SHM) systems by integrating data and power pathways into the structure. The use of this technology within a composite structure would allow engineers to place sensors from an SHM system directly where they are needed on a structure with instant power. GTL?s SNS technology offers the potential for developers to have substantial gains in vehicle performance as well. Embedding power and data transmission within the structure reduces the mass of the system by eliminating the need for wires as well the additional vehicle mass required to contain them. In the proposed effort GTL will perform a series of feasibility studies to assess and optimize the SNS technology. This work will result in the development of the SNS architecture to be employed in the Phase II effort. In this effort, GTL will perform several design iterations of the SNS technology and develop test panels for testing. At the end of the Phase II effort, GTL will deliver an SNS test panel to NASA for evaluation.


Grant
Agency: Department of Defense | Branch: Navy | Program: STTR | Phase: Phase II | Award Amount: 749.95K | Year: 2015

It is critical to the safe use of ceramic matrix composite components that information on the fracture toughness of these materials be available in order to allow an assessment of the likelihood for crack growth. Although Military Standards and American Society for Testing and Materials both serve as resources for room and elevated temperature test methods, there are no standards to obtain the interlaminar fracture toughness in CMCs. This proposal seeks to continue the development of a reliable process for measuring the Mode I and Mode II fracture toughness at any temperature for CMC materials. The process includes the selection of the best test method, the specification of the test procedures, the design of the test specimen, and the determination of the fracture toughness from the measured data.


Patent
Southern Research Institute | Date: 2015-04-17

A method for treating or preventing Hepatitis B virus infection in a subject, which comprises administering to said subject in need thereof a therapeutically effective amount of a compound represented by Formula 1: a pharmaceutically acceptable salt of thereof or solvate thereof or mixtures thereof. The subject can be an animal, particularly mammals and more particularly humans and companion animals such as cats and dogs.

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