Han S.,Korea University |
Lee B.,Korea University |
Shin G.,Songho College |
Choi J.,Korea University |
And 5 more authors.
Radiation Protection Dosimetry | Year: 2012
In this study, diagnostic reference levels (DRLs) were suggested and patient doses were analysed through the dose-area product value in dental radiography. In intraoral radiography, at three sites, i.e. molar, premolar and incisor on the maxilla and acquired third quartile values: 55.5, 46 and 36.5 mGy cm 2, respectively, were measured. In panoramic, cephalometric and cone beam computed tomography, the values were 120.3, 146 and 3203 mGy cm 2 (16 × 18 cm), respectively. It has been shown that, in intraoral radiography, the patient dose changes proportionally to the value of mA s, but the change in extraoral radiography in response to mA s could not be confirmed. The authors could confirm, however, the difference in dose according to the manufacturer in all dental radiography examinations, except for panoramic radiography. Depending on the size of hospital, there were some differences in patient dose in intraoral radiography, but no difference in patient dose in extraoral radiography. © The Author 2011. Published by Oxford University Press. All rights reserved.
Park M.-C.,Songho College
Journal of Next Generation Information Technology | Year: 2013
In this paper, the virtual flight simulation environment for open-source-based avionics test system design and implementation. This paper is proposing an integrated avionics test system for flight manipulation and simulation using the commercial simulation and development software tools such as X-Plane, LabView, and Google Earth. The proposed system is designed of seven parts of user flight control, flight simulation, flight manipulation and verification, data link and distribution, map display, data interface, and actuation systems. For a specific planned flight path, it is found that the proposed system was well operated and could be used in the flight test system.
Munkhdelger J.,Yonsei University |
Kim G.,Yonsei University |
Wang H.-Y.,M Technology Inc. |
Lee D.,Yonsei University |
And 8 more authors.
Experimental and Molecular Pathology | Year: 2014
Recent research has shown that oncogenic human papillomavirus (HPV) DNA, which is currently used in the screening and diagnosis of cervical cancer, can be detected not only in high-grade cervical lesions, but also in low-grade cervical lesions and normal tissues. For this reason, HPV tests targeting the E6 and E7 mRNA of five oncogenic HPV strains (HPV genotypes 16, 18, 31, 33, and 45), which are known to be responsible for the oncogenesis of cervical cancer, have been commercialized using a real-time nucleic acid sequence based amplification (NASBA) assay. Previous data has shown that the real-time NASBA assay has higher clinical specificity than HPV DNA testing (97.1% vs. 53.7%). However, the sensitivity of the real-time NASBA assay was lower than that of HPV DNA testing (41.1% vs. 100%). Despite the fact that there are more than 16 oncogenic HPV genotypes known to cause cervical cancer (HPV genotypes 16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, and 69), the commercialized real-time NASBA kit was designed to detect only five genotypes (16, 18, 31, 33, and 45). Therefore, in the present study, CervicGen HPV RT-qDX (Optipharm), a commercial diagnostic kit targeting a HPV E6/E7 mRNA based on RT-qPCR assay was evaluated with RNA extracted from ThinPrep® Pap samples, and the results were compared to real-time NASBA data. The sensitivity and specificity of the RT-qPCR assay were 91% and 98.6%, respectively, for the detection of cervical intraepithelial neoplasia CIN2+ high-grade cervical lesions. Therefore, the CervicGen HPV RT-qDX assay showed a significantly higher sensitivity (91.1%) compared to the real-time NASBA assay (41.1%). In normal cytohistology cases, the specificity was 98.6% and 53.7% for HPV mRNA RT-qPCR and HPV DNA testing, respectively. These results demonstrate that HPV mRNA RT-qPCR better reflects clinical diagnosis. In conclusion, it is suggested that HPV mRNA RT-qPCR overcomes the shortcomings of lower specificity seen in the DNA assay and the lower sensitivity of the commercialized HPV mRNA real-time NASBA assay when testing from ThinPrep® Pap samples. © 2014 Elsevier Inc.
Wang H.-Y.,M Technology Inc. |
Kim S.,Yonsei University |
Kim H.,Yonsei University |
Kim J.,Yonsei University |
And 6 more authors.
Annals of Clinical Microbiology and Antimicrobials | Year: 2014
Background: Sepsis is one of the main causes of mortality and morbidity. The rapid detection of pathogens in blood of septic patients is essential for adequate antimicrobial therapy and better prognosis. This study aimed to accelerate the detection and discrimination of Gram-positive (GP) and Gram-negative (GN) bacteria and Candida species in blood culture samples by molecular methods.Methods: The Real-GP®, -GN®, and -CAN® real-time PCR kit (M&D, Wonju, Republic of Korea) assays use the TaqMan probes for detecting pan-GP, pan-GN, and pan-Candida species, respectively. The diagnostic performances of the real-time PCR kits were evaluated with 115 clinical isolates, 256 positive and 200 negative blood culture bottle samples, and the data were compared to results obtained from conventional blood culture.Results: Eighty-seven reference strains and 115 clinical isolates were correctly identified with specific probes corresponding to GP-bacteria, GN-bacteria and Candida, respectively. The overall sensitivity and specificity of the real-time PCR kit with blood culture samples were 99.6% and 89.5%, respectively.Conclusions: The Real-GP®, -GN®, and -CAN® real-time PCR kits could be useful tools for the rapid and accurate screening of bloodstream infections (BSIs). © 2014 Wang et al.; licensee BioMed Central Ltd.
Park M.-C.,Songho College |
Ha S.-W.,Gyeongsang National University
Communications in Computer and Information Science | Year: 2011
Flight Waypoint visualization of the aircraft is the system which in order to be solved is used the threat against a low altitude task and terrain altitude widely. But, in order to compose a system with GPS about lower, it is widely used with the restriction must construct terrain information where it is huge to it is difficult. In this paper, flight Waypoint and economically visualization Moving Map systems of the Open-Source based for it proposes. First, UDP it leads first from X-Plane and synthetic flight path information, it acquires demonstration and terrain altitude information from the delivery receiving Google Earth. Moving from map systems terrain altitude of altitude and the present location of the aircraft about under mapping from map sever it leads and Waypoint visualization at map information which it brings. Also, altitude comparison of the terrain altitude which it follows in time interval and the aircraft it leads and indicates the terrain location which has the dangerous characteristic of collision at the projected course the monitoring screen which it provides. The outgrowth of this paper in objective of the flight algorithm research back and the flight visualization field could be used flight Waypoint visualization with the economic tool. © 2011 Springer-Verlag.