Yasuda S.,Tokai University |
Ohkura N.,Tokai University |
Suzuki K.,Tokai University |
Yamasaki M.,University of Miyazaki |
And 5 more authors.
Journal of Dairy Science | Year: 2010
To establish cheese as a dairy product with health benefits, we examined the multifunctional role of cheeses. In this report, we clarify whether different types of commercial cheeses may possess antiproliferative activity using HL-60 human promyelocytic leukemia cell lines as a cancer model. Among 12 cheese extracts tested, 6 (Montagnard, Pont-l'Eveque, Brie, Camembert, Danablue, and Blue) revealed strong growth inhibition activity and induction of DNA fragmentation in HL-60 cells. Based on the quantification of nitrogen contents in different cheese samples, a positive correlation between the ripeness of various cheeses and their antiproliferative activity tested in HL-60 cells was displayed. Four varieties of Blue cheese ripened for 0, 1, 2, or 3 mo demonstrated that the Blue cheese ripened for a long term was capable of causing the strong suppression of the cell growth and the induction of apoptotic DNA damage as well as nucleic morphological change in HL-60 cells. Collectively, these results obtained suggest a potential role of highly ripened cheeses in the prevention of leukemic cell proliferation. © 2010 American Dairy Science Association.
Dietetic substances adapted for medical use, namely, dietetic sugar and dietetic foods adapted for medical use; dietetic beverages adapted for medical purposes; dietetic food adapted for medical purposes; dietetic foods preparations adapted for medical purposes, namely, foods for individuals with special dietary requirements necessitated by medical treatments; medicated confectionery; medicated drinks and medical drinks, namely, electrolyte drinks for medical purposes; medicinal tea; herbal teas for medicinal purposes; mineral enhanced water for medical purposes; therapeutic diets intended to prevent gastro-esophageal reflux adapted for pharmaceutical purposes, namely, food for medically restricted diets; dietetic, vitamin enriched bread adapted for medical use; royal jelly for medical purposes; medicinal herbs; vitamin preparations; vitamins and mineral supplements; dietary and nutritional supplements.
Snowbrand Milk Products Co. | Date: 2010-03-23
There are provided an iron composition including a milk protein and an iron preparation, which is stable in the presence of a substance having a property of releasing iron from the composition or reducing the released iron, and foods or drinks, animal feeds, and medicines blended with the iron composition. A milk protein such as skim milk is blended into an iron preparation, thereby producing the iron composition which is stable in the presence of a substance having a property of releasing iron from the composition or reducing the released iron (e.g., vitamin C or citric acid).
Snow Brand Milk Products Co. | Date: 2011-10-14
Disclosed are: a skin whitening agent comprising, as an active ingredient, a complex of carbonic acid and/or bicarbonic acid, a metal and an LF, a decomposition product of the complex, or a complex of carbonic acid and/or bicarbonic acid, a metal and a decomposition product of an LF; and a food, beverage, feed or cosmetic comprising the skin whitening agent. The skin whitening agent can be ingested safely on a daily basis, and exhibits an excellent skin whitening effect.
Snow Brand Milk Products. Co. | Date: 2011-03-22
Disclosed is: a visceral fat accumulation inhibitor or a food or drink for inhibiting the accumulation of a visceral fat, which composes a fat globule membrane component as an active ingredient; or a agent or food or drink for promoting the increase in the blood adiponection level and/or inhibiting the decrease in the blood adiponection level, which composes a fat globule membrane component as an active ingredient. A fat globule membrane component can inhibit the accumulation of a visceral fat, and/or can promote the increase in or inhibit the decrease in the blood adiponection level.