Dawoodi I.,Smt Kashibai Navale Medical College And General Hospital Narhe
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2014
The aim of this study was to evaluate the analgesic efficacy and safety of a single dose of intravenous acetaminophen in comparison with intravenous fentanyl in patients experiencing pain after surgery. 75 patients were chosen in each group for comparison and a randomized parallel group study was initiated bearing in mind the inclusion and exclusion criteria. Two analgesic drugs, an opioid and a nonopioid were selected for the study with the idea that a non opioid drug if proved to be therapeutically more effective in relieving pain would be useful clinical indicator. Statistically it was observed that acetaminophen 1 gm intravenous dose was not as efficacious as fentanyl 100 mcg (2 ml)dose administered post operatively on a pain scale measured 4 hours after the procedure and 3 days post-surgery.