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Shinde N.S.,D B J College | Shinde N.S.,Smt Chandibai Himathmal Mansukhani College | Khot S.S.,D B J College | Khot S.S.,Smt Chandibai Himathmal Mansukhani College | And 2 more authors.
IEEE Transactions on Magnetics | Year: 2014

Ni0.5Cux/2Zn(0.5-x/2)Fe2O4 (where x \(= 0.3\) , 0.4, 0.5, and 0.6) ferrites were prepared at different chemical reaction temperatures (100 °C, 125 °C, and 150 °C) and then were further sintered using domestic microwave oven. X-ray diffraction revealed the ferrite phase formation and proved that chemical reaction temperature affects the structural properties. Magnetic properties, such as saturation magnetization, coercivity, Curie temperature, and normalized susceptibility were found to be dependent not only on composition, but also on chemical reaction temperature. Grain size was found to be in range of 41.866-200.909 nm. © 1965-2012 IEEE.


Khot S.S.,Dbj College | Khot S.S.,Smt Chandibai Himathmal Mansukhani College | Shinde N.S.,Dbj College | Shinde N.S.,Smt Chandibai Himathmal Mansukhani College | And 2 more authors.
Journal of Magnetism and Magnetic Materials | Year: 2015

Lithium ferrites have attracted considerable attention because they have been used as replacements for garnets due to their low cost. A series of polycrystalline ferrite samples were prepared with the composition of Li XZn(0.6-2X)Cu0.4Fe2O 4(X=0.05, 0.1, 0.15, 0.2, 0.25, 0.3) at chemical reaction temperature 150 °C by sintering with microwave assisted combustion method. The characterization shows the formation of single phase cubic structure when carried out by using the X-rays technique and I-R technique. Magnetization parameters such as saturation magnetization, coercivity, magnetic moment were calculated by using the Hysteresis graph. The Curie temperature obtained using the susceptibility data are found to be in the range 350-700 °C. Anhysteric remanent magnetization is used for estimating the grain size and domain structure of the composition. An attempt has been made to synthesis the nano-particles at lower reaction temperature by using non-conventional microwave sintering method. The advantage of this method is its lower sintering temperature and time compared to the conventional ceramic technique and direct formation of nano-ferrites without ball-milling. © 2014 Elsevier B.V.


Raut V.V.,Bhabha Atomic Research Center | Pandey S.M.,Smt Chandibai Himathmal Mansukhani College | Sainis J.K.,Bhabha Atomic Research Center
Annals of Botany | Year: 2011

Background: and ScopeIn eukaryotes, chromatin remodelling complexes are shown to be responsible for nucleosome mobility, leading to increased accessibility of DNA for DNA binding proteins. Although the existence of such complexes in plants has been surmised mainly at the genetic level from bioinformatics studies and analysis of mutants, the biochemical existence of such complexes has remained unexplored. • Methods: Histone H1-depleted donor chromatin was prepared by micrococcal nuclease digestion of wheat nuclei and fractionation by exclusion chromatography. Nuclear extract was partially purified by cellulose phosphate ion exchange chromatography. Histone octamer trans-transfer activity was analysed using the synthetic nucleosome positioning sequence in the absence and presence of ATP and its analogues. ATPase activity was measured as 32Pi released using liquid scintillation counting. • Key Results: ATP-dependent histone octamer trans-transfer activity, partially purified from wheat nuclei using cellulose phosphate, showed ATP-dependent octamer displacement in trans from the H1-depleted native donor chromatin of wheat to the labelled synthetic nucleosome positioning sequence. It also showed nucleosome-dependent ATPase activity. Substitution of ATP by ATP analogues, namely ATPγS, AMP-PNP and ADP abolished the octamer trans-transfer, indicating the requirement of ATP hydrolysis for this activity. • Conclusions: ATP-dependent histone octamer transfer in trans is a recognized activity of chromatin remodelling complexes required for chromatin structure dynamics in non-plant species. Our results suggested that wheat nuclei also possess a typical chromatin remodelling activity, similar to that in other eukaryotes. This is the first report on chromatin remodelling activity in vitro from plants. © The Author 2011.


Patil A.G.,Birla College | Patil A.G.,Smt Chandibai Himathmal Mansukhani College | Ansari A.Y.,Birla College | Koli S.P.,Birla College | Patil D.A.,Smt Chandibai Himathmal Mansukhani College
Asian Journal of Chemistry | Year: 2013

Chromatographic techniques can be used to document phytochemical fingerprints and quantitate chemical markers in the herbal raw material. Sufoof-e-mohazzil (SM) is one of the most trusted and sold Unani formulation. Sufoof-e-mohazzil which has been used in Unani Pharmacy since antiquity is used as antiobesity agent, digestive and for controlling high cholesterol levels. Thymol as phytochemical marker was quantified using HPTLC from in-house and two marketed formulations (SM-1 and SM-2) of Sufoof-e-mohazzil. Quantification was carried out on silica gel 60 F254 pre-coated HPTLC plates using toluene: ethyl acetate: GAA [97:3:0.2, (v/v/v)] as mobile phase. The response was linear over the range of 1 μg/mL to 5 μg/mL with correlation coefficient of 0.986. Accuracy of the method was checked by recovery studies at three different levels and the average percentage recoveries were found to be 97.94 ± 0.5. The concentration of the thymol was found to be 2.780 μg/mL for in-house formulation whereas 2.180 and 1.768 μg/mL for SM-1 and SM-2 respectively. The method was validated for linearity, precision, accuracy and ruggedness and can be used for routine quality control of Unani formulation Sufoof-e-mohazzil.


Nabar B.M.,Smt Chandibai Himathmal Mansukhani College | Shepal K.B.,Smt Chandibai Himathmal Mansukhani College | Lele H.M.,Smt Chandibai Himathmal Mansukhani College | Lokegaonkar S.P.,Smt Chandibai Himathmal Mansukhani College
West African Journal of Applied Ecology | Year: 2012

Mosquitoes are one of the most medically significant vectors, and they transmit parasites and pathogens, which have major impact on the human population. The vector borne diseases caused by mosquitoes, such as dengue, malaria, yellow fever, chickungunya and filariasis, the major health problems in India. The Waldhuni river of the Thane district is highly polluted and now termed as nalla. The purpose of the study was to document the diversity of the harmful mosquito population in the vicinity of the Waldhuni nalla. Water samples were collected from eight different sites of the Waldhuni nalla and were checked for pH, temperature, biological oxygen demand (BOD), chemical oxygen demand (COD), total suspended solids (TSS) and mosquito population. Respective sites were monitored for the cases of malaria, dengue and filariasis. The biostatistical analysis was performed to study the correlation between water pollution, mosquito population and the mosquito borne diseases. Positive correlation between BOD, COD and TSS with mosquito population was found. Similarly, the significant relationship among malarial cases and Culex population was observed. The study revealed that Waldhuni nalla and its vicinity are good habitat for the adult mosquito in spite of being rich in the pollution.


Mishra R.K.,Banaras Hindu University | Mishra R.K.,Smt Chandibai Himathmal Mansukhani College | Singh S.K.,Banaras Hindu University
Journal of Ayurveda and Integrative Medicine | Year: 2013

Background: The flower buds of Syzygium aromaticum (clove) have been used in indigenous medicines for the treatment of male sexual disorders in Indian subcontinent. Objective: To evaluate the effect of Syzygium aromaticum flower bud on male reproduction, using Parkes (P) strain mice as animal model. Materials and Methods: Mice were orally administered lipid soluble components of Syzygium aromaticum flower bud in doses of 15, 30, and 60 mg/kg body weight for 35 days, and several male reproductive endpoints were evaluated. Results: Treatment with lower dose (15 mg) of Syzygium increased the motility of sperm and stimulated the secretory activities of epididymis and seminal vesicle, while higher doses (30 and 60 mg) had adverse effects on sperm dynamics of cauda epididymidis and on the secretory activities of epididymis and seminal vesicle. Libido was not affected in treated males; however, a significant decrease in litter in females sired by males treated with higher doses of Syzygium was recorded. Conclusion: Treatment with Syzygium aromaticum flower bud causes dose-dependent biphasic effect on male reproductive indices in P mice; lower dose of Syzygium appears stimulatory, while the higher doses have adverse effect on male reproduction. The results suggest that the lower dose of Syzygium may have androgenic effect, but further studies are needed to support this contention.


PubMed | Smt Chandibai Himathmal Mansukhani College
Type: Journal Article | Journal: Indian journal of pharmaceutical sciences | Year: 2010

Extracts of Aloe vera whole plant, Eucalyptus globulus leaves, Ficus infectoria bark, Ficus religiosa bark and Piper betel leaves were studied for antibacterial activity on resistant and sensitive strains, isolated from skin and soft tissue infections. A combination of hot alcoholic extracts of Ficus infectoria, Ficus religiosa and Piper betel were found to be more effective against all the isolates. The combined extract was formulated in different ointment bases such as polyethylene glycol, gelatin, sodium alginate, carbopol, cream base and honey. These were then evaluated to find a suitable base for preparation of an ointment. In vitro study of the release of antimicrobials and kill-time studies of the herbal ointments was carried out against multi-drug resistant isolate of Pseudomonas. The ointment showed bactericidal activity within 2 h against the resistant strain of Pseudomonas spp.

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