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Wound debridement compositions containing the proteolytic enzyme Seaprose and use of such compositions in wound treatment for the enzymatic debridement of wounds.


Patent
Smith & Nephew | Date: 2017-01-31

Oxidation resistant crosslinked ultrahigh molecular weight polyethylene (UHMWPE) is described, wherein at least two different additives in the manufacture synergistically increase the oxidation resistance of crosslinked UHMWPE. This allows the manufacture of oxidation resistant crosslinked UHMWPE using lower levels of additives and/or lower levels of crosslinking irradiation or chemicals. The lower levels of additives and/or crosslinking produce crosslinked UHMWPE having desired physical properties not possible without the synergistic interaction of the additives. This crosslinked UHMWPE may be used in medical prostheses such as in bearing components having desired physical properties such as wear resistance and oxidation resistance not possible without the synergistic interaction of the additives.


Patent
Smith & Nephew | Date: 2017-05-17

An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are moved by a device (which may be a single pump or two pumps) for moving fluid through a flow path which passes through the dressing and a means for providing simultaneous aspiration and irrigation of the wound. The apparatus also comprises means to apply high frequency vibrational energy, e.g. ultrasound, to the wound bed. The former removes materials deleterious to wound healing, while distributing materials that are beneficial in promoting wound healing over the wound bed. The latter promotes healing. The dressing and a method of treatment using the apparatus.


Patent
Smith & Nephew | Date: 2017-05-17

A polyurethane material for the detection or sensing of species or stimulus comprising a polyurethane network comprising immobilised therein, or modified by the immobilisation therein of, a hydrophilic polymer comprising a ligand or moiety for the detection or sensing of species or stimulus and an indicator for indicating detection or sensing wherein species or stimulus is selected from chemical or biological species or stimulus; the material for medical, dental, hygiene, point of use sterilisation, sanitation, personal care, biosurveillance or packaging use, the use thereof preferably for detecting and/or sensing or binding bacteria, or for detecting or sensing pH or for detection or scanning with use of a reader; a Kit and a device comprising the same; and a process for the preparation thereof.


Patent
Smith & Nephew | Date: 2017-05-17

A device for sensing and/or detecting species or stimulus at a locus, preferably at a fluid or moist locus by means of fluid communication therewith, comprising a surface configured to contact the locus, wherein the surface comprises a polyurethane material which material comprises a polyurethane polymer network having a hydrophilic polymer immobilised therein wherein the hydrophilic polymer comprises immobilised therein a ligand or moiety for detecting or sensing species or stimulus and an indicator for indicating detection or sensing prior to contact with the locus and change in indication as a function of species or stimulus present at the locus wherein species or stimulus are selected from chemical and biological species or stimulus; the use thereof preferably for detecting and/or sensing or binding bacteria, or for detecting or sensing pH or for detection or scanning with use of a reader; and a Kit.


Patent
Smith & Nephew | Date: 2017-03-29

A method and apparatus are disclosed for applying negative pressure to a wound site. The apparatus comprises a source of negative pressure, a processing element, and a memory comprising instructions configured to, when executed on the processor, cause the apparatus to perform the steps of, via the source of negative pressure, attempting to generate a desired negative pressure at the wound site, if the desired negative pressure has not been generated after a first predetermined period of time, deactivating the source of negative pressure for a second predetermined period of time, and subsequently attempting to generate the desired negative pressure at the wound site.


Patent
Smith & Nephew | Date: 2017-03-08

The present disclosure relates to a resection device. The resection device includes an outer tubular member; and an inner tubular member disposed within the outer tubular member, the inner tubular member including a burr having a body with flutes extending along a length of the body, the flutes including parabolic wave patterns located along surface edges of the flutes. In an embodiment, the parabolic wave patterns extend along entire lengths of the flutes. Other resection devices are also disclosed.


Patent
Smith & Nephew | Date: 2017-04-26

The present invention provides a coating comprising a bioactive material and an antimicrobial agent, wherein the concentration of said antimicrobial agent varies throughout the thickness of the coating.


Patent
Smith & Nephew | Date: 2017-05-10

An instrument (10, 100) for locating an axis of a blocking screw is disclosed. The instrument (10, 100) is applicable for a retrograde installation of a femoral intramedullary device or an antegrade installation of a tibial intramedullary device. The instrument (10, 100) includes a drill jig (11, 105) with a radiolucent frame portion (14, 120) and a mounting portion (12, 110). The mounting portion (12, 110) is adapted to connect to an intramedullary device (204), and the frame portion (14, 120) has at least one aperture (18, 22, 24, 25, 28, 29, 126, 137, 337) for locating the axis of the blocking screw (210). The drill jig (11, 105) is adjustable to locate the aperture (18, 22, 24, 25, 28, 29, 126, 137, 337) in a longitudinal or rotational direction relative to the intramedullary device (204).


Patent
Smith & Nephew | Date: 2017-09-13

Implants, and processes for installing them, which replace the medial condyle and portions of the patellofemoral channel but preferably not portions of the lateral condyle that articulate relative to the tibia. Processes are provided which allow proper location and orientation of an anterior resection and a distal resection on the femur, which make use of a transition point which can be designated on the bone, for navigating proper positioning of such implants. Proper positioning of the implant relative to the femur for insuring a smooth transition between lateral portions of the implant and the lateral condyle is thus reduced to determining proper medial / lateral location of the implant on the anterior and distal resections. Such implants and processes can allow, among other things, for controlled location and orientation of an implant on the bone which saves lateral compartment bone, which eliminates the need to sacrifice the anterior and posterior cruciate ligaments, and which is adapted for minimally invasive surgery with its attendant benefits.

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