Skn Medical College

Pune, India

Skn Medical College

Pune, India
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Khatib K.I.,Prayag Hospital | Khatib K.I.,Skn Medical College | Borawake K.S.,Prayag Hospital
Journal of Clinical and Diagnostic Research | Year: 2014

Consumption of a glass of bottle gourd juice is thought to work as a health “tonic” and part of traditional healthy living practices in India. The juice may in certain circumstances turn bitter with increased levels of the cytotoxic compound called Cucurbitacins. If the bitter juice is consumed it causes a toxic reaction in the gut, leading to abdominal discomfort/pain, vomiting, hematemesis, and hypotension which may be rarely fatal, especially in persons with pre-existing illness. In the absence of clear cut history regarding the consumption of the bitter bottle gourd juice and the initiation of symptoms, the differential diagnosis for the above symptoms will include diseases causing gastrointestinal bleed with hypotension and/or shock.We report a case of bitter bottle gourd poisoning presenting with abdominal symptoms, hematemesis and shock and with an initial differential diagnosis of septicemia with septic shock and multi-organ involvement. We conduct a literature review and ponder the various differential diagnoses of this clinical scenario. © 2014, Journal of Clinical and Diagnostic Research. All rights reserved.


Sham S.,Mimsr Medical College | Chetana N.,Skn Medical College
Indian Journal of Otolaryngology and Head and Neck Surgery | Year: 2014

The objective of this study was to report and present an approach to combine functional and esthetic technique of endoscopic nasal tumor resection with anterior cranial fossa extension resection in a case of Esthesioneuroblastoma (ENB), a rare slow growing malignant neoplasm of the olfactory mucosa. For this purpose, the mass was excised by nasal endoscopic approach with microdebrider and anterior craniotomy with bi-coronal incision. The cribriform plate defect was reconstructed with temporalis fascia and nasal defect with fascia and rotated middle turbinate. Radiotherapy was given. At 4 years follow up no evidence of tumor locally or systemic metastasis were seen. In conclusion endoscopic excision complimented with anterior craniotomy for the anterior cranial fossa extension of resectable ENB with post-op radiotherapy is an effective treatment modality satisfying both oncosurgical as well as esthetic requirements. © 2011 Association of Otolaryngologists of India.


Karne S.S.,SKN Medical College | Bhalerao N.S.,SKN Medical College
Journal of Clinical and Diagnostic Research | Year: 2016

Introduction: Carpal Tunnel Syndrome (CTS) is an entrapment neuropathy that occurs due to compression of median nerve in the carpal tunnel and hypothyroidism is one of the important causes of CTS. Aim: To study clinical profile of carpal tunnel syndrome in patients with primary hypothyroidism. Materials and Methods: This was cross-sectional study done in Smt. Kashibai Navale Medical College, Pune, Maharashtra. Adult patients with diagnosis of primary hypothyroidism were included in this study. Patients with other possible causes of CTS were excluded. Detailed medical history was obtained and all patients underwent clinical examination and nerve conduction study by electrophysiological method. Results: Total 36 adult patients were included in this study, 86.1% females and 13.9% males. CTS were found in 6 (16.7%) patients. Increased Body Mass Index (BMI) and presence of clinical symptoms and/or signs of CTS correlated independently with presence of CTS in hypothyroidism. (p-value- 0.03 and < 0.0001 respectively). No correlation was found between gender, age of the patient, duration of disease, serum TSH level, aetiology of the disease, thyroid hormone replacement therapy and occurrence of CTS in hypothyroidism. Conclusion: Increase in BMI is an important risk factor for CTS in hypothyroidism and clinical evidence of CTS is a very sensitive parameter for the same. © 2016, Journal of Clinical and Diagnostic Research. All rights reserved.


Somani S.S.,Mimsr Medical College | Naik C.S.,Skn Medical College | Bangad S.V.,Mimsr Medical College
Indian Journal of Otolaryngology and Head and Neck Surgery | Year: 2010

To describe endoscopic power assisted adenoidectomy and review the experience with the procedure demonstrating its safety and efficacy. Prospective study of 44 patients aged between 7 to 15 years undergoing power assisted adenoidectomy between Jan 2004 and July 2006. Tertiary care private teaching hospital. Forty four consecutive children with adenoid hypertrophy undergoing power assisted adenoidectomy. Therapeutic endoscopic adenoidectomy using microdebrider. Operative time, blood loss, complications, completeness and depth of removal, surgeon's satisfaction and recovery period. The average operative time was 12 min (range: 8-16 min) and average blood loss was 30 ml (range: 24-42 ml). Complete resection was possible under vision with few complications. The surgeon satisfaction was high and post-operative recovery good. Power assisted adenoidectomy is quick, precise and safe. There is good visualization during resection thus improving precision and ensuring complete removal of adenoid tissue. © 2011 Association of Otolaryngologists of India.


Ingole J.R.,SKN Medical College | Patel R.D.,SKN Medical College | Ingole S.I.,SKN Medical College
Journal of Clinical and Diagnostic Research | Year: 2015

Introduction: Vitamin B12 deficiency is mainly diagnosed in symptomatic patients. However, the deficiency may also be prevalent in asymptomatic patients. Our aim was to study the prevalence of Vit B12 deficiency in IT professionals (Information Technology Professionals from Software industry) who presented for routine health screening and to correlate the deficiency to various parameters. Materials and Methods: This was single centre, observational study comprising of 84 IT professionals. The data was collected in structured format. The study was designed to identify prevalence of Vit B12 deficiency and correlate to other factors such as type of diet, income level & regular use of medication (such as Antacid & Metformin).Results: Total 28 individuals were found to be deficient (33.34%). Prevalence of Vit B12 deficiency amongst Vegetarian and non vegetarian diet adhering subjects was 47.5% and 20.45% respectively. B12 deficiency was also prevalent in high income age group. Further chronic intake of PPI (Proton pump inhibitor) and Metformin was associated with prevalence of 37.5% and 33.34% in the present study. Conclusion: During health screening of IT Professionals, significant prevalence of Vit B12 deficiency was noted across all income groups &non vegetarian diet consuming subjects also. There is significant correlation between Vit B12 deficiency with chronic use of PPI and Metformin. © 2015, Journal of Clinical and Diagnostic Research. All rights resereved.


Karandikar Y.S.,SKN Medical College | Bansude A.S.,BVDU Medical College | Angadi E.A.,BVDU Medical College
Journal of Clinical and Diagnostic Research | Year: 2016

Introduction: The traditional texts designate Cow Ghee as Medhya Rasayana, beneficial for mental alertness and memory. There has been concern about increased risk of cardiovascular disease due to its high percentage of saturated fatty acids in ghee. Amongst all edible fats, nutrition composition of cow ghee and butter is comparatively similar. Hence we had planned a study to assess effect of cow ghee on memory and lipid profile. Aim: So the aim of this study is to assess the effect of cow ghee on memory and lipid profile Materials and Methods: Nootropic activity of test drugs was assessed by Elevated Plus Maze (EPM) and Morris Water Maze (MWM) model. Rats were divided into four groups namely control, Piracetam, cow ghee and butter. All drugs were given orally for 21 days. Transfer latency was measured in EPM model and probe test was done in MWM model. Results: Cow ghee and butter group showed no significant effect on memory in EPM and MWM model. There was reduction in weight of animals in Cow Ghee group and increase in weight with Butter. In both the models there was a significant increase in Triglyceride (TG) and Very Low Density Lipoproteins (VLDL) levels of rats in butter groups and increase in TG and VLDL of rats with cow ghee in EPM model. Conclusion: The result of experiment suggests that no beneficial effect cow ghee and butter on cognition. However,ghee is relatively safer when compared to Butter in considering lipid profile. © 2016, Journal of Clinical and Diagnostic Research. All rights reserved.


PubMed | SKN Medical College
Type: Journal Article | Journal: Journal of orthopaedic case reports | Year: 2016

A typical presentations of tuberculosis are not uncommon. Periprosthetic infection with tuberculosis after total joint replacement has well published. Tuberculosis of the elbow following open reduction internal fixation of a distal humerus fraeture is extremely rare.We report case of a healthy, immunocompetenet 49-year-old male who underwent open reduction and internal fixation with bicolumnar plating for distal humerus fracture and presented after 18 month with cystic swelling over medial aspect of operated site. There was no wound dehiscence and the underlying fracture was healed well without any signs of implant loosening or bony involvement. Cystic swelling was excised and histopathology provided the diagnosis of tuberculosis. Patient was treated with anti tubercular chemotherapy and patient made uneventful recovery.Although synovial tuberculosis after fracture fixation is a rare entity, tuberculosis should be kept as a differential diagnosis. Surgeons should have high index of suspicion to diagnose atypical presentations of tuberculosis.


PubMed | SKN Medical College
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2016

Vitamin B12 deficiency is mainly diagnosed in symptomatic patients. However, the deficiency may also be prevalent in asymptomatic patients. Our aim was to study the prevalence of Vit B12 deficiency in IT professionals (Information Technology Professionals from Software industry) who presented for routine health screening and to correlate the deficiency to various parameters.This was single centre, observational study comprising of 84 IT professionals. The data was collected in structured format. The study was designed to identify prevalence of Vit B12 deficiency and correlate to other factors such as type of diet, income level & regular use of medication (such as Antacid & Metformin).Total 28 individuals were found to be deficient (33.34%). Prevalence of Vit B12 deficiency amongst Vegetarian and non vegetarian diet adhering subjects was 47.5% and 20.45% respectively. B12 deficiency was also prevalent in high income age group. Further chronic intake of PPI (Proton pump inhibitor) and Metformin was associated with prevalence of 37.5% and 33.34% in the present study.During health screening of IT Professionals, significant prevalence of Vit B12 deficiency was noted across all income groups & non vegetarian diet consuming subjects also. There is significant correlation between Vit B12 deficiency with chronic use of PPI and Metformin.


PubMed | SKN Medical College and BVDU Medical College
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2016

The traditional texts designate Cow Ghee as Medhya Rasayana, beneficial for mental alertness and memory. There has been concern about increased risk of cardiovascular disease due to its high percentage of saturated fatty acids in ghee. Amongst all edible fats, nutrition composition of cow ghee and butter is comparatively similar. Hence we had planned a study to assess effect of cow ghee on memory and lipid profile.So the aim of this study is to assess the effect of cow ghee on memory and lipid profile.Nootropic activity of test drugs was assessed by Elevated Plus Maze (EPM) and Morris Water Maze (MWM) model. Rats were divided into four groups namely control, Piracetam, cow ghee and butter. All drugs were given orally for 21 days. Transfer latency was measured in EPM model and probe test was done in MWM model.Cow ghee and butter group showed no significant effect on memory in EPM and MWM model. There was reduction in weight of animals in Cow Ghee group and increase in weight with Butter. In both the models there was a significant increase in Triglyceride (TG) and Very Low Density Lipoproteins (VLDL) levels of rats in butter groups and increase in TG and VLDL of rats with cow ghee in EPM model.The result of experiment suggests that no beneficial effect cow ghee and butter on cognition was seen. However, ghee is relatively safer when compared to Butter in considering lipid profile.


PubMed | Mimsr Medical College and Skn Medical College
Type: Journal Article | Journal: Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India | Year: 2014

The objective of this study was to report and present an approach to combine functional and esthetic technique of endoscopic nasal tumor resection with anterior cranial fossa extension resection in a case of Esthesioneuroblastoma (ENB), a rare slow growing malignant neoplasm of the olfactory mucosa. For this purpose, the mass was excised by nasal endoscopic approach with microdebrider and anterior craniotomy with bi-coronal incision. The cribriform plate defect was reconstructed with temporalis fascia and nasal defect with fascia and rotated middle turbinate. Radiotherapy was given. At 4years follow up no evidence of tumor locally or systemic metastasis were seen. In conclusion endoscopic excision complimented with anterior craniotomy for the anterior cranial fossa extension of resectable ENB with post-op radiotherapy is an effective treatment modality satisfying both oncosurgical as well as esthetic requirements.

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