Singapore Institute of Neurotechnology

Singapore, Singapore

Singapore Institute of Neurotechnology

Singapore, Singapore
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Thomas Yeo B.T.,National University of Singapore | Thomas Yeo B.T.,Singapore Institute of Neurotechnology | Thomas Yeo B.T.,Massachusetts General Hospital | Krienen F.M.,Massachusetts General Hospital | And 12 more authors.
Cerebral Cortex | Year: 2015

The association cortex supports cognitive functions enabling flexible behavior. Here, we explored the organization of human association cortex by mathematically formalizing the notion that a behavioral task engages multiple cognitive components, which are in turn supported by multiple overlapping brain regions. Application of the model to a large data set of neuroimaging experiments (N=10 449) identified complex zones of frontal and parietal regions that ranged from being highly specialized to highly flexible. The network organization of the specialized and flexible regions was explored with an independent resting-state fMRI data set (N=1000). Cortical regions specialized for the same components were strongly coupled, suggesting that components function as partially isolated networks. Functionally flexible regions participated in multiple components to different degrees. This heterogeneous selectivity was predicted by the connectivity between flexible and specialized regions. Functionally flexible regions might support binding or integrating specialized brain networks that, in turn, contribute to the ability to execute multiple and varied tasks. © 2014 The Author.


Yu H.,Singapore Institute of Neurotechnology | Yu H.,National University of Singapore | Huang S.,Singapore Institute of Neurotechnology | Chen G.,Singapore Institute of Neurotechnology | And 2 more authors.
Mechatronics | Year: 2013

Rehabilitation robots have direct physical interaction with human body. Ideally, actuators for rehabilitation robots should be compliant, force controllable, and back drivable due to safety and control considerations. Series Elastic Actuators (SEA) offers many advantages for these applications and various designs have been developed. However, current SEA designs face a common performance limitation due to the compromise on the spring stiffness selection. This paper presents a novel compact compliant force control actuator design for portable rehabilitation robots to overcome the performance limitations of current SEAs. Our design consists of a servomotor, a ball screw, a torsional spring between the motor and the ball screw, and a set of translational springs between the ball screw nut and the external load. The soft translational springs are used to handle the low force operation, while the torsional spring with high effective stiffness is used to deal with the large force operation. It is a challenging task to design the controller for such a novel design as the control system needs to handle both the force ranges. In this paper, we develop the force control strategy for this actuator. First, two dynamical models of the actuator are established based on different force ranges. Second, we propose an optimal control with friction compensation and disturbance rejection which is enhanced by a feedforward control for the low force range. The proposed optimal control with feedforward term is also extended to the high force range. Third, a switching control strategy is proposed to handle a transition between low force and high force control. The mathematical proof is given to ensure the stability of the closed-loop system under the proposed switching control. Finally, the proposed method is validated with experimental results on a prototype of the actuator system and is also verified with an ankle robot in walking experiments. © 2013 Elsevier Ltd. All rights reserved.

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