Mukka, India


Mukka, India
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Srikousthubha,Kannur Medical College | Sukesh,S.I.M.S and RC | Raghuveer C.V.,S.I.M.S and RC | Hingle S.,S.I.M.S and RC
Journal of Clinical and Diagnostic Research | Year: 2013

Aim and Introduction: Urinary bladder lesions, non-neoplastic and neoplastic, are collectively responsible for significant morbidity and mortality throughout the world. The present study aimed to study the histopathology of various lesions of the bladder through cystoscopic biopsies. Material and Methods: The present prospective study aimed to study the histopathology of various lesions of the urinary bladder through cystoscopic biopsies. All patients who visited Urology Outpatients Department for haematuria and dysuria were subjected to cystoscopy. Results: Histopathological examinations revealed an equal share of non neoplastic lesions and neoplastic lesions. Amongst the non neoplastic lesions, 84% were inflammatory lesions. Urothelial tumours (96%) formed the bulk amongst neoplastic lesions. Conclusion: This article has stressed upon the importance of histopathological examinations in evaluating bladder pathologies.

Devaki R.N.,JSS University | Manjunatha Goud B.K.,Ras al-Khaimah Medical and Health Sciences University | Devi O.S.,Vidya Nursing College | Deepa K.,JSS University | And 3 more authors.
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2012

Diabetes mellitus is a group of metabolic disease characterized by hyperglycemia resulting from defective insulin secretion, insulin action or both. Studies on chronic complications of diabetes established the role of glycosylated hemoglobin (HbA1c) as a marker of evaluation of long term glycemic control and risk for chronic complications. This is a cross sectional study carried out on 40 diabetic patients and 50 normal individuals, between the age group of 40-60 years attending medicine OPD were included as study subjects. Diabetes was diagonsed based on laboratory and clinincal co-relation. 5ml of fasting venous sample was taken from study sujects and following parameters were estimated LDL, FPG and glycatedhemoglobin. The values of HbA1c and FPG were statistically significant in diabetic subjects when compared to controls (p< 0.001). The levels of LDL-C were increased in diabetic subjects but were not statistically significant. In conclusion, significant co-relation between HbA1c and LDL-C levels can be used as a potential biomarker for predicting dyslipidemia in type 2 diabetic patients in addition to long term glycemic control.

Samuel S.E.,Mangalore University | Nayak A.,SIMS and RC | Kotian M.S.,KMC
Biomedicine (India) | Year: 2013

Introduction: The effectiveness of exercise interventions in older people with milder levels of balance dysfunction remains largely unexplored. There is scarce evidence on the effects of exercise interventions designed to prevent falls on the quality of life in older adults. Aim: The aim of this study was to compare functional training and balance training in their influence on quality of life among older adults with mild to moderate fall risk. Materials and Methods: Community dwelling individuals over 65 years of age with balance dysfunction were randomly allocated into functional and balance training interventions for 24 weeks. Quality of life was measured with the WHOQOL- BREF instrument before and after the intervention. Statistical analysis was done by using Student's unpaired "t" test. Results: A total of 116 older adults (82 female, 34 male, mean age of 67.31 ± 3.06 years) completed the study, with 58 subjects in each group. WHOQOL-BREF score changes for the functional training group were 22.71±8.77on the physical domain, 19.59±9.90 on the psychological domain and 2.57±5.31 on the social domain and 22.28±7.76 on the environmental domain. For the balance training group, score changes were 8.21±7.30on the physical domain, 9.95±6.72on the psychological domain and 1.93±5.67 on the social domain and 10.50±6.67 on the environmental domain. While both interventions were beneficial, functional training led to greater improvement in quality of life among community dwelling older adults.

Vaidya K.A.,SIMS and RC | Adiga P.,SIMS and RC | Lakshman I.K.,SIMS and RC
Journal of Clinical and Diagnostic Research | Year: 2012

Villar's Nodule or primary umbilical endometriosis is a rare condition, with an estimated incidence of 0.5 to 1% among all the patients with endometrial ectopia. Endometriosis remains a diagnostic and therapeutic enigma even today, largely due to its variable presentations. We are hereby reporting a case of primary umbilical endometriosis due to its rarity and unusual presentation.

Satheesha K.S.,SIMS and RC | Somesh M.S.,SIMS and RC | Pai S.R.,SIMS and RC | Patil G.V.,SIMS and RC
Journal of Clinical and Diagnostic Research | Year: 2012

Introduction: The model of single artery occlusion in subhuman primates was studied, to verify whether there is any correlation between micro-circulatory perfusion impairment and area of infarction after occlusion of middle cerebral artery and to find out whether there is any definite 'reperfusion window' which could be used effectively to prevent or reduce the area of infarction. Materials and Methods: For the present study 24 healthy adult monkeys of either sex were procured and the Middle cerebral artery (MCA) was occluded and reperfused for given set of time periods and the infarction size of the brain was determined. Results: The percentage of the infarction size after occluding the blood vessel increased considerably, as the time interval prolonged. After the reperfusion of the arteries for shorter intervals like 30 min, 4 hours and 12 hours, there was a significant decrease in the infarct size, whereas there was no effect on the infarct size after 12 hours. Conclusion: In the regions of focal cerebral ischaemia, the ad¬verse effect of focal ischemia may be minimized if, in the acute phase, functional microcirculation is increased by some therapeutic intervention aimed at augmenting blood flow through the ischemic region.

Shetty A.,SIMS and RC | Narasimha A.,SIMS and RC | Jayalakshmi V.J.,SIMS and RC
Breast Disease | Year: 2016

The physiological changes of the breast during pregnancy and lactation make the clinical, radiological and pathological evaluation of a breast mass challenging. Galactoceles are benign lesions containing milk, and generally occur post partum. Fine needle aspiration cytology is a simple, quick and effective technique for the diagnosis of the same during this period, and in case of galactocele the same can be both diagnostic and therapeutic. Although the cytological features of galactocele are straight forward, a few rare interesting variations can be encountered posing a diagnostic challenge to the reporting cytopathologist. We present a case of galactocele in a twenty five year old lactating female with tyrosine crystals on cytology. Milk is composed of a wide variety of proteins and minerals, leading to the formation of calcium lactate or tyrosine crystals under rare circumstances when the milieu is acidic. This is one of the rare cases of crystallizing galactoceles reported in literature till date. © 2016 IOS Press and the authors. All rights reserved.

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