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Kolkata, India

Sidho Kanho Birsha University is a state university established in 2010 and situated in Purulia, West Bengal, India. Tapati Mukherjee has been appointed as the first Vice-Chancellor of the University. The focus of the University would be to promote and protect indigenous culture and language, and especially the Santali language.Sidho-Kanho-Birsha University began its nascent but promising journey as an academic institution of higher learning from the day it was created as a state University in 2010. Since then it has been a chronicle of consistent effort and ascendant drive to keep alive the dynamics of academic flourish. Currently the university is on the throes of novelty of vision and constitutive endeavours to script a new dimension in the annals of higher education. The Post-Graduate Departments of the university started functioning from the session 2011-12 with total number of twelve academic Departments . Over the years in an expansive and forward looking drive, we have enhanced the number into seventeen Departments with the introduction of five new departments many of which are situated in the frontier areas of Science and Social science. We are proud to initiate the Department of Tribal Studies to fulfill the mandate of the University which is situated in the remotest part of the State but having a vibrant social history and indigenous culture. We are soon going to open the Department of Performing Arts and introduction of such wings would provide a greater dimension in our efforts for growth and further development. The University is proud to have highly qualified faculty members, motivated students and adequate supporting and administrative officers and staff in order to absorb the forces of modernization and globalization in the field of Higher Education.Sidho Kanho Birsha University , Purulia aspires to be a premier center for advanced knowledge and top quality research. As a university located in Purulia, it strives to emulate global standards in the domain of higher education and intellectual knowhow. In today`s times, owing to technological access and communicational facilities, it is always possible to keep in touch with the rest of the global academia and therefore, SKBU as an institution of advanced learning and research has got its root firmly planted in the advancement of local knowledge and aspiring at the same to time to elevate its academic credentials in the global educational map. It is situated in a place which has been known as a remote and backward region, but since its inception, SKBU has succeeded in instilling a rippling effect of hope and acceleration in the surroundings. As a university it has acquired the faith of the people and it has generated the required momentum of advancement and thirst for higher education. In other words, this university has ushered in hope and optimism and it has restored faith among the youth about their future. Wikipedia.

Deb J.,Indian Association for The Cultivation of Science | Majumder J.,Indian Association for The Cultivation of Science | Bhattacharyya S.,Sidho Kanho Birsha University | Jana S.S.,Indian Association for The Cultivation of Science
BMC Cancer | Year: 2014

Background: Increasingly, the role of chronic inflammation and its mediators in tumor generation and progression is gaining importance in the field of cancer research. In this context, candidature of non steroidal anti-inflammatory drugs (NSAIDs) as potential anti-tumor therapeutic agent is being evaluated globally. In the present study we have evaluated the anti-cancer effect of a series of newly synthesized naproxen derivatives on human breast cancer cell lines. Methods: MCF-7 (poorly invasive) and MDA-MB-231 (highly invasive) cells were treated with different concentrations of naproxen sodium and its derivatives in vitro, and the underlying mechanism of action was monitored by employing studies related to induction of apoptosis, activation of caspases, cell-cycle progression, synthesis of PGE2 and cellular migration. Results: After a preliminary screening using MCF-7 and MDA-MB-231 cells, it was evident that naproxen derivative 4 has a better killing property compared to its parent compound naproxen sodium (NS). On further investigation, it was apparent that the observed growth inhibitory activity on MDA-MB-231 cells after treatment with 4, was not due to cell cycle arrest but due to an early induction of apoptosis and subsequent induction of caspases 3 and 9. Derivative 4 could also inhibit COX activity in MDA-MB-231 cells as evidenced by reduction in prostaglandin E2 secretion. Moreover, 4 was capable of delaying the overall migration rate of MDA-MB-231 cells in vitro.Conclusion: In this study we report that a naproxen-derivative (4) has powerful anti-inflammatory and anti-tumor properties as it induces appreciable amount of apoptosis in breast cancer cell line, and can also delay migration of cancer cells (MDA-MB-231) which would in turn delay cancer cell invasion and formation of secondary tumours in primary breast cancer patients. Thus, we propose that 4 is worthy of further investigation due to its potential as a therapeutic agent in anti-tumor treatment regimen. © 2014 Deb et al.

Roy S.,Shibpur Dinobundhoo Institution College | Mondal P.,Vivekananda Mahavidyalaya | Sengupta P.S.,Vivekananda Mahavidyalaya | Dhak D.,Sidho Kanho Birsha University | And 3 more authors.
Dalton Transactions | Year: 2015

A 1:2 copperII complex of 1-amino-4-hydroxy-9,10-anthraquinone (QH) having the molecular formula CuQ2 was prepared and characterized by elemental analysis, NMR, FTIR, UV-vis and mass spectroscopy. The powder diffraction of the solid complex, magnetic susceptibility and ESR spectra were also recorded. The presence of the planar anthraquinone moiety in the complex makes it extremely difficult to obtain a single crystal suitable for X-ray diffraction studies. To overcome this problem, density functional theory (DFT) was used to evaluate an optimized structure of CuQ2. In the optimized structure, it was found that there is a tilt of the two planar aromatic anthraquinone rings of the complex with respect to each other in the two planes containing the O-Cu(ii)-O plane. The present study is an important addition to the understanding of the structural aspects of metal-anthracyclines because there are only a few reports on the actual structures of metal-anthracyclines. The theoretical vibrational spectrum of the complex was assigned with the help of vibrational energy distribution analysis (VEDA) using potential energy distribution (PED) and compared with experimental results. Being important in producing the biochemical action of this class of molecules, the electrochemical behavior of the complex was studied in aqueous and non-aqueous solvents to find certain electrochemical parameters. In aqueous media, reduction involves a kinetic effect during electron transfer at an electrode surface, which was characterized very carefully using cyclic voltammetry. Electrochemical studies showed a significant modification in the electrochemical properties of 1-amino-4-hydroxy-9,10-anthraquinone (QH) when bound to CuII in the complex compared to those observed for free QH. This suggests that the copper complex might be a good choice as a biologically active molecule, which was reflected in the lack of stimulated superoxide generation by the complex. This journal is © The Royal Society of Chemistry 2015.

Das B.C.,Vidyasagar University | Das B.,Sidho Kanho Birsha University | Mondal S.K.,Vidyasagar University
Applied Soft Computing Journal | Year: 2015

The presence of multiple markets create profitable opportunities to the supply chain system. In this regard, this paper consists of the joint relationship between a manufacturer and multiple markets in which manufacturer offers part-payment to the markets due to their collection of finished products during the production run time. Here it is also considered that manufacturer is facilitated with credit period by raw material supplier where credit period has been presented as an interactive fuzzy fashion. In this paper, two types of deterioration have been assumed such as one for finished products and the other for raw materials. A solution algorithm is presented to get fuzzy optimal profit for the proposed integrated production inventory system optimizing production run time. A numerical example is used to illustrate the proposed model. Finally, sensitivity analysis has been carried out with respect to the major parameters to demonstrate the feasibility of the proposed model. © 2014 Elsevier B.V. All rights reserved.

Kuiri P.K.,Sidho Kanho Birsha University | Majhi J.K.,Banwarilal Bhalotia College
Plasmonics | Year: 2016

Theoretical calculations of optical absorption (OA) spectra of Zn nanoparticles (NPs) in silica glass, using a simple model, have been resulted in appearance of three OA bands, all of which are found to blueshift with decrease in NP radius due to quantum confinement effects of free electrons. The intensities of the OA bands are seen to increase with increase in incident light energy. Importantly, all the three OA bands have been found to satisfy, accurately, the surface plasmon resonance (SPR) condition. All these observations clearly indicate that the observed OA bands are originated from the SPR absorptions in Zn NPs, but not due to inter-band absorption. © 2016 Springer Science+Business Media New York

Kshetri R.,Sidho Kanho Birsha University
Journal of Instrumentation | Year: 2014

Full energy peak, single escape peak and double escape peak areas have been extracted for an escape suppressed clover detector. Results have been obtained for the single crystal and addback modes of operation as well as the active and passive suppression cases at several gamma energies. We have compared the ratio of single escape peak areas in addback mode with that of single crystal mode to study if the single escape peak gains or loses counts due to addback mode. Detailed analysis has been performed for quantifying the advantages of using addback mode and active suppression. Comparison is made for different types of clover detectors with different volumes. © 2014 IOP Publishing Ltd and Sissa Medialab srl.

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