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Selvarajan S.,Siddha Regional Research Institute | Gayathri Devi V.,Siddha Regional Research Institute | John A.,Siddha Central Research Institute | Jeyakannan J.,Siddha Central Research Institute | And 2 more authors.
International Journal of Pharmacy and Technology | Year: 2015

Tinospora cordifolia commonly known as Guduchi is used in traditional systems of medicine for general debility, dyspepsia, fevers and urinary diseases. The plant also possesses antiviral as well as antibacterial properties. The present study provides a detailed pharmacognostic study based on its physicochemical, macroscopic, microscopic and chromatographic features. The physicochemical parameters such as loss on drying, solubility in different solvents, ash content, acid insoluble ash, water soluble ash, volatile oil, fibre content etc. were determined by standard methods. Anatomical features of the stems of Tinospora cordifolia were determined. For this the sample was fixed in FAA, cast into paraffin blocks and sectioned with the help of Rotary Microtome. The stomata morphology, venation pattern and trichome distribution were studied. Microscopic descriptions of tissues were supplemented with micrographs wherever necessary. Photographs of different magnifications were taken with Nikon Labphot 2 Microscopic Unit. Powder microscopy was carried out using standard methods. HPTLC profile of the methanolic plant extract was carried out in short UV, long UV and using anisaldehyde - sulphuric acid as detection reagent. The Rf values of the spots developed were noted which is an important parameter for identification of plant materials. The pharmacognostical parameters along with the HPTLC profile may be utilized to identify the drug material and for laying down the pharmacopoeial standards. © 2015 International Journal of Pharmacy and Technology. All rights reserved.


John A.,Siddha Central Research Institute | Gayathri Devi V.,Siddha Regional Research Institute | Selvarajan S.,Siddha Regional Research Institute | Gopakumar K.,Siddha Central Research Institute
International Journal of Pharmacy and Technology | Year: 2015

Gossypiumherbaceum Linn. belongs to the family Malvaceae, is commonly known as Karpas or Cotton. The plantoccurs in Middle East countries,Central Asia and Western India. The area of its greatest variability is found in Baluchistan, Iran, Afghanistan and Russian Turkestan. The cultivated types are found in India, China and Middle East countries. Gossypiumherbaceum has been widely used in theproduction of food and medicine as well. The parts of the plant used in medicine are seeds, leaves, flowers, root and root bark. The plant possesses antifertility, antispermatogenic, antitumor, abortifacient, contraceptive, antidiabetic, antiulcer, antiviral and antibacterial activities. In the present paper, a detailed study on Gossypiumherbaceum(flower) based on its physico-chemical analysis and High Performance Thin Layer Chromatographic (HPTLC) studies were carried out to lay down the pharmacopoeial standards. The physico-chemical parameters such as loss on drying at 105oC, solubility in water and alcohol, ash content and acid insoluble ash were determined by standard methods. A preliminary phytochemical study was carried out using different extractives of the plant material. HPTLC profile of the ethanol extract of the plant material was carried out in UV 254nm, UV 366nm and using vanillin- sulphuric acid as derivatisation reagent and the Rf values were noted. All these parameters are helpful in identification and standardization of the flower of Gossypiumherbaceum. © 2015, International Journal of Pharmacy and Technology. All rights reserved.


John A.,Siddha Regional Research Institute | Devi V.G.,Siddha Regional Research Institute | Singh A.,Central Council for Research in Ayurveda science | Gopakumar K.,Siddha Regional Research Institute
International Journal of Pharmacy and Technology | Year: 2013

Plants are the major source of naturally occurring medicaments. The efficacy and popularity of any system of medicine depends on the quality of medicines used for the treatment. To assure the quality of the drug, standardisation has become very essential and need of the present hour. The present paper deals with a detailed study on the root of a common herbal drug, Sida cordifolia Linn, known as Chitraamutti in the Siddha system of medicine. The study was based on the physico-chemical and preliminary phytochemical properties of the plant material to lay down the pharmacopoeial standards. Sida cordifolia Linn. (Family: Malvaceae), is an annual or perennial short, erect, greyishgreen, softly hairy or pubescent woody undershrub, 0.5-1m high. The plant has been used in fever, rheumatism and piththa diseases for centuries. Chitraamutti is used as an ingredient for the preparation of Siddha formulations such as Vaathasura kudineer, Chitraamutti thailam, Sarapungavilvaathi legyam, Dhirakshathi choornam etc. The analytical methods include determination of physico-chemical parameters, thin layer chromatographic (TLC) studies and high performance thin layer chromatographic (HPTLC) profiles. The physico-chemical parameters like loss on drying at 105°C, ash content, acid insoluble ash, water soluble ash, solubility in water and alcohol, volatile oil, etc. were determined by standard methods. The fluorescence characters of the drug in different solvents were detected in visible, short UV and long UV light. The preliminary phytochemical tests were carried out using different extractives of the plant material. TLC and HPTLC fingerprints were taken. These results can be conveniently used as a tool for standardization of the single drug.


Mubarak H.,Siddha Regional Research Institute | Masilamani G.,Siddha Regional Research Institute
Indian Journal of Marine Sciences | Year: 2012

Considerable marine resources are contributing to the pharmaceutics of Siddha Medicine. Among them formulations prepared out of Palagarai (Cypraea moneta Linn.) are the choice of drug for many indications in Siddha medical practice. Literatures of ancient science and current available materials are reviewed to highlight the importance of Palagarai. This information may serve as an evidence to establish current research in traditional medical systems.

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