Shrisathyasai Medical College And Research Institute

India

Shrisathyasai Medical College And Research Institute

India
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Shanmuga Priya R.,ShriSathyaSai Medical College And Research Institute | Malligai E.,Chettinad Medical College and Research Institute | Suganya,ShriSathyaSai Medical College And Research Institute | Rajagopalan B.,ShriSathyaSai Medical College And Research Institute
International Journal of Pharmaceutical Sciences Review and Research | Year: 2016

Metabolic syndrome has already emerged as the major health problem in both developed and developing countries that causes huge economic burden to the world. Insulin resistance and inflammation are the two main underlying factors which leads to Metabolic syndrome. Oxidative stress plays an important role in the etiology and progression of the metabolic syndrome. Increased production of reactive oxygen species (ROS) species may leads to the production of pro inflammatory adipokines TNF -α and IL-6 which leads to insulin resistance. Glutathione(GSH), the most important non protein antioxidant in the cell requires Gammaglutamyl transferase enzyme for its metabolism. Gammaglutamyl transferase also known to have a pro-oxidant role may indicate the incidence of cellular oxidative stress. The aim of the study is to determine the levels of Gamma glutamyl transferase in metabolic syndrome patients and in normal healthy controls. 82 individuals were included in the study, 41 are selected as controls and 41 are selected as metabolic syndrome patients. BMI, Lipid profile, GGT and uric acid were estimated and Statistical analysis was done using SPSS (version 21). GGT and body mass index values are higher in cases than controls. High Density Lipoprotein and Total Cholesterol values are lower in cases than controls. The study may be concluded that Gamma glutamyl transferase a marker of oxidative stress is important in the diagnostic and prognostic aspect of metabolic syndrome. © 2016, Global Research Online. All rights reserved.


Raman R.T.,Shrisathyasai Medical College And Research Institute | Hemanathan G.,Shrisathyasai Medical College And Research Institute | Manimaran D.,Shrisathyasai Medical College And Research Institute | Khan D.M.,Shrisathyasai Medical College And Research Institute | Anuradha S.,Shrisathyasai Medical College And Research Institute
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2014

Filariasis commonly presents with symptoms due to lymphatic obstruction leading to nonpitting edema and only rarely presents as a mass lesion. We encountered a case which presented as a paratesticular mass without a hydrocele. This kind of mass presentation can misleadthe clinician for a neoplastic lesion and may lead to unnecessary panic for the patient. We outline this case of filariasis mimicking as paratesticular neoplasm with review of literature.

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