Kanazawa-shi, Japan
Kanazawa-shi, Japan

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Patent
Shiseido Company | Date: 2016-11-29

The present invention relates to a method for producing artificial skin, comprising: adding a matrix metalloproteinase inhibitor and a heparanase inhibitor to an artificial skin formation culture medium comprising human epidermal keratinocytes and human dermal fibroblasts, culturing the cells in the artificial skin formation culture medium, and forming artificial skin.


Patent
Shiseido Co. | Date: 2017-02-08

The present application provides an oil-in-water type emulsified cosmetic which has the effect of beautifying the appearance of skin and also excels in emulsion stability. The oil-in-water type emulsified cosmetic according to the present invention is characterized by comprising (A) 1 to 20 mass% of a hydrophobized titanium oxide having an average particle size of at least 0.1 m; (B) a sugar ester having a carboxyl group within the structure; (C) a liquid higher fatty acid; (D) a higher alcohol; (E) a non-ionic surfactant; (F) water; and (G) an oil component.


Patent
Shiseido Co. | Date: 2017-05-03

The purpose of the present invention is to provide an oil-in-water emulsion composition exhibiting high UV-protective capabilities with which it is possible to uniformly and stably disperse a hydrophobized metal oxide into an inner phase (oil phase) without detracting from the inherent fresh sensation on use of an oil-in-water emulsion composition even when a high amount of the hydrophobized metal oxide is compounded therewith. In summary, the present invention is an oil-in-water emulsion composition characterized by including (A) 0.1-5 mass% of polyether-modified silicone having an HLB(Si) of 5-14, (B) one or more hydrophilic thickeners, (C) a metal oxide hydrophobized by an agent other than metal soap, and (D) nonvolatile oil other than silicone oil, the (C) hydrophobized metal oxide being present in the inner phase.


Patent
Shiseido Co. | Date: 2017-05-03

The present invention relates to a water-based cosmetic wherein a hydrophobic powder is directly dispersed in the water phase of the water-based cosmetic, the water-based cosmetic having the excellent smoothness, water resistance and cosmetic durability characteristic of hydrophobic powders, while maintaining the refreshing sensation of use that is inherent in water-based cosmetics. The invented water-based cosmetic is characterized by comprising: (A) 0.1 to 5 mass% of a polyether-modified silicone having an HLB (Si) of 5 to 14; (B) one or more hydrophilic thickeners; (C) a polyol and/or an ethyl alcohol; and (D) one or more hydrophobic powders chosen from among metal oxides hydrophobically treated without using a metal soap, hydrophobic organic powders and silicone powders; wherein the (D) hydrophobic powder is dispersed in the water phase.


Patent
Shiseido Company | Date: 2017-06-14

The present invention provides a raw material for cosmetics with which cosmetics excellent in stability and the feeling in use and without skin irritation can easily be produced. A raw material for cosmetics comprising a core-corona type microgel dispersion obtained by the radical polymerization of a polyethylene oxide macromonomer represented by the formula (1), a hydrophobic monomer represented by formula (2), and a cross-linking monomer represented by the formula (3) under defined conditions, including: (A) the mole ratio of said polyethylene oxide macromonomer versus said hydrophobic monomers is in the range of 1/1 to 10:/250 (mole/mole), (B) said cross-linking monomers is in the range of 0.1 to 1.5 % by weight relative to said hydrophobic monomers, (C) said hydrophobic monomer is a monomer composition comprising at least one methacrylic acid selected from the group consisting of methacrylic acid derivatives that have alkyl groups having 1 to 8 carbon atoms, (D) solvent used for polymerization is a mixed solvent of water and polyol that is at least one polyol selected from the group consisting of dipropylene glycol, 1,3-butylene glycol, and isoprene glycol, and (E) said mixed solvent of water and polyol has water versus said polyol ratio that is in the range of 90/10 to 10/90 % by mass at 20 C.


Patent
Shiseido Co. | Date: 2017-06-07

The present invention provides a novel sirtuin-1 activating agent, and a formulation for suppressing cell senescence caused by oxidative stress, comprising the agent. In particular, the invention provides a sirtuin-1 activating agent consisting of a plant body or solvent extract of Peucedanum japonicum Thunb., and a formulation for suppressing cell senescence due to oxidative stress, comprising the agent.


Patent
Shiseido Co. | Date: 2017-06-07

The present invention provides an oil-based cosmetic that can easily be washed out with warm water and is excellent in water resistance. The oil-based cosmetic of the present invention is characterized by comprising (a) to (c):(a) 1 to 25 mass % of a block-type alkylene oxide derivative represented by the below-described formula (I)(b) 1 to 15 mass % of a siliconized pullulan and/or trimethylsiloxysilicic acid(c) 10 mass % or less of waterR^(1)O-[(EO)_(p)(PO)_(q)(EO)_(r)]-R^(2)(I)(In the above formula, EO is an oxyethylene group and PO is an oxypropylene group. The symbols p, q, and r are the average addition mole numbers, and they are p1, r1, 10p+ r70, and 10q60. R^(1) and R^(2) are either identical or different and they are either a hydrogen atom or a hydrocarbon group having 1 to 3 carbon atoms.)


Patent
Shiseido Company | Date: 2017-06-14

An objective of the present invention is to provide a solid powder cosmetic excellent in impact resistance and usability despite that boron nitride and spherical resin particle are blended in a large amount. The present invention provides a solid powder cosmetic comprising: 12-30 mass% of synthetic fluorphlogopite iron; 5-15 mass% of boron nitride; and 5-15 mass% of phenyl-modified silicone spherical elastic powder.


Patent
Shiseido Company | Date: 2016-02-24

An oil-enclosed powdery composition includes an oil-enclosable powder; further comprising; a platy powder, aluminum hydroxide coating the platy powder, having a surface of a specific surface area of at least 10 m^(2)/g, and a fluorine compound coating the aluminum hydroxide; and an oil droplet having at least 50% by mass of hydrocarbon oil based on a total oil component and at least 2.010^(2 )N/m of a surface tension value as a total oil component; wherein the oil-enclosable powder encompassing the oil droplet is like powder having an average particle size of 10 to 150 m and the oil-enclosed powdery composition is liquefiable by inunction.


Sunscreen products that do not require the use of organic, ultraviolet-absorbing agents are provided. Effective protection of the skin from ultraviolet light is attained by increasing the amounts of titanium dioxide and zinc oxide. To mask the excessive whiteness that would otherwise result from the oxides, the sunscreen products contain multilayer-type encapsulations containing pigments. Before use, the pigments are enveloped in capsules that muffle the pigments color. When the sunscreen product is applied to the skin, the capsules break and the pigments are released to counter the excessive whiteness due to titanium dioxide and zinc oxide. Sunscreen product precursors, from which these sunscreen products can be generated by stirring, are also provided. A sunscreen product package contains the sunscreen product precursor and a stirring ball. A method of ultraviolet protection is provided by shaking the sunscreen product package and applying the sunscreen product thus generated to the skin.

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