Wayne, PA, United States
Wayne, PA, United States

Time filter

Source Type

News Article | February 21, 2017
Site: www.businesswire.com

NEW YORK--(BUSINESS WIRE)--Bristol-Myers Squibb Company (NYSE:BMY) announced today that it has appointed Robert J. Bertolini, Matthew W. Emmens and Theodore R. Samuels to its Board of Directors, effective immediately. In connection with these appointments, the Board will temporarily expand to 14 directors until the 2017 Annual Meeting, to be held on May 2, 2017. Only 11 directors will stand for election at the meeting. Bristol-Myers Squibb also announced that it has entered into an accelerated share repurchase (“ASR”) program to repurchase, in aggregate, $2 billion of Bristol-Myers Squibb’s common stock. Giovanni Caforio, M.D., chief executive officer of Bristol-Myers Squibb, said, “Bristol-Myers Squibb continues to take decisive action to best position the company for growth driven by our leading portfolio of Immuno-Oncology medicines, including Opdivo, and by an exciting diversified portfolio of medicines such as Eliquis and Orencia. We are committed to advancing the promising opportunities represented by our portfolio and pipeline in oncology as well as continuing our efforts to diversify through promising pipeline agents in heart failure, immunoscience and fibrosis. Our new directors add important experience and skills managing large businesses and operations, broaden our overall expertise in the pharmaceutical sector and more broadly in capital markets, and complement extremely well the existing skills on our Board. We look forward to working with them to advance our business strategy. “In addition, the decision to implement an accelerated share repurchase program demonstrates our focus on enhancing shareholder returns as we continue to capitalize on our long-term opportunities,” Caforio continued. “I am pleased to welcome Bob, Matt and Ted to the Board, and know that their unique skill sets and experience will be invaluable to the company going forward,” said Lamberto Andreotti, chairman of the Board. “As I announced in December, I will be retiring as chairman, effective May 2, 2017. I am happy to be leaving with such a strong Board in place and am confident Bristol-Myers Squibb has a bright future.” Bristol-Myers Squibb noted that, since JANA Partners LLC (“JANA”) became a Bristol-Myers Squibb shareholder in the fourth quarter of 2016, members of the Board and management have engaged in discussions with representatives of JANA to better understand their views. Today’s Board appointments follow discussions between the two parties regarding the Board. “These three new independent directors will add valuable industry knowledge and fresh perspectives to the Board, and shareholders stand to reap a substantial benefit from the company's sizable investment in its undervalued shares,” said Barry Rosenstein, founder and managing partner of JANA. “These are two very positive developments for all Bristol-Myers Squibb shareholders.” Togo D. West, Jr., the board’s lead independent director, said, “Bristol Myers-Squibb benefits from a strong Board that comprises leaders who have diverse expertise relevant to the company’s strategy and mission. We welcome Bob, Matt and Ted to the Board and look forward to their contributions.” “Bristol-Myers Squibb is widely regarded as an innovator and a leader with a strong portfolio of assets that will help drive value for shareholders,” said Samuels. “I look forward to working with my colleagues on the Board to continue advancing the company’s important mission.” “I am honored to join the Bristol-Myers Squibb Board and to work alongside some of the great minds in science and medicine,” said Emmens. “With a diverse portfolio and a strong pipeline, I am confident that Bristol-Myers Squibb will continue to find solutions for patients with high unmet medical needs.” “I am pleased to be joining the Board during a period of innovation and scientific discovery,” said Bertolini. “I look forward to joining my fellow directors and the management team in helping Bristol-Myers Squibb with the compelling opportunities ahead.” Accelerated Share Repurchase Bristol-Myers Squibb has entered into an ASR program with each of Morgan Stanley & Co. LLC and Goldman, Sachs & Co. to repurchase, in aggregate, $2 billion of Bristol-Myers Squibb’s common stock. The company expects to fund the repurchase with a combination of debt and cash. Approximately 80 percent of the shares to be repurchased under the transaction will be received by Bristol-Myers Squibb on February 28, 2017. The total number of shares ultimately repurchased under the program will be determined upon final settlement and will be based on a discount to the volume-weighted average price of Bristol-Myers Squibb’s common stock during the ASR period. The program is part of Bristol-Myers Squibb’s existing share repurchase authorization. Bristol-Myers Squibb anticipates that all repurchases under the ASR will be completed by the end of the second quarter of 2017. Bristol-Myers Squibb notes that it is commencing a 10b5-1 plan to facilitate continuous stock repurchase activity by the company. Robert J. Bertolini Bob Bertolini, who currently serves on the boards of Charles River Laboratories and Actelion Pharmaceuticals Ltd., is the former president and CFO of Bausch & Lomb. Previously, Bertolini served as executive vice president and CFO at Schering-Plough Corporation and as a Partner and Pharmaceutical Industry Practice Leader at PricewaterhouseCoopers LLC. He brings extensive financial and accounting expertise and significant strategic and operational leadership experience in the biopharmaceutical industry to the Board of Bristol-Myers Squibb. Matthew W. Emmens Matt Emmens is the former chairman, president and CEO of Vertex Pharmaceuticals. Prior to Vertex, Emmens served as chairman and CEO of Shire Pharmaceuticals and as president and CEO of Astra Merck, the joint venture between Merck and Astra AB. He brings to the Board of Bristol-Myers Squibb more than 40 years of experience in the biopharmaceutical industry, with significant management, business development and operations expertise. Theodore R. Samuels Ted Samuels, who currently serves on the boards of Perrigo Company plc and Stamps.com, has more than 35 years of financial industry experience. As the former president of Capital Guardian Trust Company and a former global equity portfolio manager at Capital Group, Samuels has extensive business and operational experience, particularly with respect to economics, capital markets and investment decision making. Morgan Stanley is serving as financial advisor to Bristol-Myers Squibb and Kirkland & Ellis LLP is serving as legal counsel. Covington & Burling LLP is serving as legal counsel to Bristol-Myers Squibb in connection with the ASR. About Bristol-Myers Squibb Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases. For more information about Bristol-Myers Squibb, visit us at BMS.com or follow us on LinkedIn, Twitter, YouTube and Facebook. These materials contain certain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 regarding, among other things, statements relating to goals, plans and projections regarding the company’s financial position, results of operations, market position, product development and business strategy. These statements may be identified by the fact that they use words such as "anticipate," "estimates," "should," "expect," "guidance," "project," "intend," "plan," "believe" and other words and terms of similar meaning in connection with any discussion of future operating or financial performance. Such forward-looking statements are based on current expectations and involve inherent risks and uncertainties, including factors that could delay, divert or change any of them, and could cause actual outcomes and results to differ materially from current expectations. These factors include, among other things, effects of the continuing implementation of governmental laws and regulations related to Medicare, Medicaid, Medicaid managed care organizations and entities under the Public Health Service 340B program, pharmaceutical rebates and reimbursement, market factors, competitive product development and approvals, pricing controls and pressures (including changes in rules and practices of managed care groups and institutional and governmental purchasers), economic conditions such as interest rate and currency exchange rate fluctuations, judicial decisions, claims and concerns that may arise regarding the safety and efficacy of in-line products and product candidates, changes to wholesaler inventory levels, variability in data provided by third parties, changes in, and interpretation of, governmental regulations and legislation affecting domestic or foreign operations, including tax obligations, changes to business or tax planning strategies, difficulties and delays in product development, manufacturing or sales including any potential future recalls, patent positions, the ultimate outcome of any litigation matter, and our level of indebtedness. These factors also include the company’s ability to execute successfully its strategic plans, including its business development strategy, the expiration of patents or data protection on certain products, including assumptions about the company’s ability to retain patent exclusivity of certain products, and the impact and result of governmental investigations. There can be no guarantees with respect to pipeline products that future clinical studies will support the data described in this release, that the compounds will receive necessary regulatory approvals, or that they will prove to be commercially successful; nor are there guarantees that regulatory approvals will be sought, or sought within currently expected timeframes, or that contractual milestones will be achieved. For further details and a discussion of these and other risks and uncertainties, see the company's periodic reports, including the annual report on Form 10-K, quarterly reports on Form 10-Q and current reports on Form 8-K, filed with or furnished to the SEC. The company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise.


News Article | May 15, 2017
Site: globenewswire.com

-- Paolo Tombesi named as Chief Financial Officer -- -- Paul Streck, M.D., appointed as Chief Medical Officer -- -- Eugene Sullivan, M.D., assumes role of Chief Product Strategy Officer -- BRIDGEWATER, N.J., May 15, 2017 (GLOBE NEWSWIRE) -- Insmed Incorporated (Nasdaq:INSM), a global biopharmaceutical company focused on the unmet needs of patients with rare diseases, today announced the appointment of Paolo Tombesi as Chief Financial Officer, effective June 1, 2017, and Paul Streck, M.D., as Chief Medical Officer, effective June 5, 2017. Additionally, Eugene Sullivan, M.D., has been appointed to the newly created role of Chief Product Strategy Officer. “These management changes will strengthen our already solid leadership team and add critical skills to our organization as we collectively advance the clinical development of our portfolio and prepare for the potential commercialization of liposomal amikacin for inhalation,” said Will Lewis, president and chief executive officer of Insmed. Mr. Tombesi brings over 20 years of experience in the biotechnology and pharmaceutical sector, most recently serving as Vice President and Chief Financial and Administrative Officer of Novartis Pharmaceuticals Corporation. In addition, Mr. Tombesi was also a member of Novartis’s Pharma Executive Committee, Commercial Leadership Team, Corporate Compliance Committee, Global Pharma Finance Leadership Team and Global Country CFO Team. He joined Novartis in 2006 as Head of Finance Region Europe, Oncology, and held several positions of increasing responsibility, including serving as Managing Director and CFO of Novartis Japan. Prior to joining Novartis, Mr. Tombesi held various financial positions with Bristol-Myers Squibb. His career began in consumer goods with Unilever NV and Johnson & Johnson. He holds a degree in business and managerial ecomonics from Rome’s La Sapienza University and a degree in accounting from Duca degli Abruzzi Roma. Dr. Streck joins Insmed with over 25 years of clinical development, management and leadership expertise. He most recently served as Vice President, Global Medical Specialty Franchise, Immuno-inflammation at GlaxoSmithKline where he was responsible for portfolio strategy, including drug launch, life cycle management, post-registration clinical strategy and health economics. Previously, he held various positions with functions ranging from clinical development to medical affairs to commercial with Shire Pharmaceuticals and AMGEN USA, Inc.  Dr. Streck also practiced in the Jefferson Health System at Thomas Jefferson University. He received his medical degree from Jefferson Medical College and was a resident in oral and maxillofacial surgery at Thomas Jefferson University Hospital. Dr. Streck also holds a doctorate of dental medicine from Temple University School of Denistry, a Masters of Business Administration from the Duke University Fuqua School of Business and board certification in oral and maxillofacial surgery from the American Board of Oral and Maxillofacial Surgery. Dr. Sullivan joined Insmed as Chief Medical and Scientific Officer in 2015, and has more than 20 years of experience with a focus on pulmonary and orphan diseases. Prior to joining Insmed, and in addition to other roles within the industry, Dr. Sullivan held several positions at the U.S. Food and Drug Administration. Dr. Sullivan’s extensive product strategy development experience uniquely qualifies him for the newly-created position as he will be tasked with overseeing the advancement of Insmed’s product pipeline. “Paolo’s extensive financial and commercial understanding of the pharmaceutical industry will assist us in addressing the challenges faced by rapidly growing, global businesses. Paul brings proven management and leadership skills that are critical to us as a multi-product development organization. Paul has played a crucial role in the clinical development, launch or commercial marketing of more than 25 medications across a broad range of indications, including rare and orphan diseases. In his new role, Gene will continue to rely on his broad clinical and regulatory background and will focus his directly relevant experience with the FDA and demonstrated product strategy expertise on the development of our ongoing portfolio strategy,” added Mr. Lewis. Insmed Incorporated is a global biopharmaceutical company focused on the unmet needs of patients with rare diseases. The company is advancing a global phase 3 clinical study of ARIKAYCE® (liposomal amikacin for inhalation) for adult patients with treatment refractorynontuberculous mycobacteria (NTM) lung disease caused by Mycobacterium avium complex (MAC), which is a rare and often chronic infection that is capable of causing irreversible lung damage and can be fatal. There are currently no approved inhaled products specifically indicated for the treatment of refractory NTM lung disease caused by MAC in the United States or the European Union. Insmed's earlier-stage clinical pipeline includes INS1007, a novel oral reversible inhibitor of DPP1 with therapeutic potential in non-cystic fibrosis bronchiectasis, and INS1009, an inhaled nanoparticle formulation of a treprostinil prodrug that may offer a differentiated product profile for rare pulmonary disorders, including pulmonary arterial hypertension. For more information, visit www.insmed.com. "Insmed" and "ARIKAYCE" are the company's trademarks. All other trademarks, trade names or service marks appearing in this press release are the property of their respective owners. This press release contains forward looking statements.  "Forward-looking statements," as that term is defined in the Private Securities Litigation Reform Act of 1995, are statements that are not historical facts and involve a number of risks and uncertainties.  Words herein such as "may," "will," "should," "could," "would," "expects," "plans," "anticipates," "believes," "estimates," "projects," "predicts," "intends," "potential," "continues," and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) may identify forward-looking statements. The forward-looking statements in this press release are based upon the company's current expectations and beliefs, and involve known and unknown risks, uncertainties and other factors, which may cause the company's actual results, performance and achievements and the timing of certain events to differ materially from the results, performance, achievements or timing discussed, projected, anticipated or indicated in any forward-looking statements. Such factors include, among others: uncertainties in the research and development of our existing product candidates, including due to delays in patient enrollment or failure of our preclinical studies or clinical trials to satisfy pre-established endpoints; failure to develop, or to license for development, additional product candidates, including a failure to attract experienced third party collaborators; failure to obtain, or delays in obtaining, regulatory approval from the United States Food and Drug Administration, the European Medicines Agency, and other regulatory authorities for our product candidates or their delivery devices, including due to insufficient clinical data or selection of endpoints that are not satisfactory to regulators; failure of third parties on which we are dependent to conduct our clinical trials and to manufacture sufficient quantities of our product candidates for clinical or commercial needs; failure to comply with license agreements that are critical for our product development, including our license agreements with PARI Pharma GmbH and AstraZeneca AB; lack of safety and efficacy of our product candidates; inaccuracies in our estimate of the size of the potential markets for our product candidates; failure to maintain regulatory approval for our product candidates, once received, due to a failure to satisfy post-approval regulatory requirements, such as the need for post-clinical trials; uncertainties in the rate and degree of market acceptance of product candidates, if approved; uncertainties in the timing, scope and rate of reimbursement for our product candidates; competitive developments affecting our product candidates; inaccurate estimates regarding our future capital requirements, including those necessary to fund milestone payments or royalties owed to third parties; inability to repay our existing indebtedness or to obtain additional financing when needed; failure to obtain, protect and enforce our patents and other intellectual property; inability to create an effective direct sales and marketing infrastructure or to partner with a third party that offers such an infrastructure for distribution of our product candidates; the cost and potential reputational damage resulting from litigation to which we are a party, including, without limitation, the class action lawsuit pending against us; failure to comply with the laws and regulations that impact our business; loss of key personnel; and changes in laws and regulations applicable to our business, including those related to pricing and reimbursement of our product candidates.  For additional information about the risks and uncertainties that may affect our business, please see the factors discussed in Item 1A, "Risk Factors," in the company's Annual Report on Form 10-K for the year ended December 31, 2016. The company cautions readers not to place undue reliance on any such forward-looking statements, which speak only as of the date of this press release. The company disclaims any obligation, except as specifically required by law and the rules of the Securities and Exchange Commission, to publicly update or revise any such statements to reflect any change in expectations or in events, conditions or circumstances on which any such statements may be based, or that may affect the likelihood that actual results will differ from those set forth in the forward-looking statements.


News Article | May 15, 2017
Site: globenewswire.com

-- Paolo Tombesi named as Chief Financial Officer -- -- Paul Streck, M.D., appointed as Chief Medical Officer -- -- Eugene Sullivan, M.D., assumes role of Chief Product Strategy Officer -- BRIDGEWATER, N.J., May 15, 2017 (GLOBE NEWSWIRE) -- Insmed Incorporated (Nasdaq:INSM), a global biopharmaceutical company focused on the unmet needs of patients with rare diseases, today announced the appointment of Paolo Tombesi as Chief Financial Officer, effective June 1, 2017, and Paul Streck, M.D., as Chief Medical Officer, effective June 5, 2017. Additionally, Eugene Sullivan, M.D., has been appointed to the newly created role of Chief Product Strategy Officer. “These management changes will strengthen our already solid leadership team and add critical skills to our organization as we collectively advance the clinical development of our portfolio and prepare for the potential commercialization of liposomal amikacin for inhalation,” said Will Lewis, president and chief executive officer of Insmed. Mr. Tombesi brings over 20 years of experience in the biotechnology and pharmaceutical sector, most recently serving as Vice President and Chief Financial and Administrative Officer of Novartis Pharmaceuticals Corporation. In addition, Mr. Tombesi was also a member of Novartis’s Pharma Executive Committee, Commercial Leadership Team, Corporate Compliance Committee, Global Pharma Finance Leadership Team and Global Country CFO Team. He joined Novartis in 2006 as Head of Finance Region Europe, Oncology, and held several positions of increasing responsibility, including serving as Managing Director and CFO of Novartis Japan. Prior to joining Novartis, Mr. Tombesi held various financial positions with Bristol-Myers Squibb. His career began in consumer goods with Unilever NV and Johnson & Johnson. He holds a degree in business and managerial ecomonics from Rome’s La Sapienza University and a degree in accounting from Duca degli Abruzzi Roma. Dr. Streck joins Insmed with over 25 years of clinical development, management and leadership expertise. He most recently served as Vice President, Global Medical Specialty Franchise, Immuno-inflammation at GlaxoSmithKline where he was responsible for portfolio strategy, including drug launch, life cycle management, post-registration clinical strategy and health economics. Previously, he held various positions with functions ranging from clinical development to medical affairs to commercial with Shire Pharmaceuticals and AMGEN USA, Inc.  Dr. Streck also practiced in the Jefferson Health System at Thomas Jefferson University. He received his medical degree from Jefferson Medical College and was a resident in oral and maxillofacial surgery at Thomas Jefferson University Hospital. Dr. Streck also holds a doctorate of dental medicine from Temple University School of Denistry, a Masters of Business Administration from the Duke University Fuqua School of Business and board certification in oral and maxillofacial surgery from the American Board of Oral and Maxillofacial Surgery. Dr. Sullivan joined Insmed as Chief Medical and Scientific Officer in 2015, and has more than 20 years of experience with a focus on pulmonary and orphan diseases. Prior to joining Insmed, and in addition to other roles within the industry, Dr. Sullivan held several positions at the U.S. Food and Drug Administration. Dr. Sullivan’s extensive product strategy development experience uniquely qualifies him for the newly-created position as he will be tasked with overseeing the advancement of Insmed’s product pipeline. “Paolo’s extensive financial and commercial understanding of the pharmaceutical industry will assist us in addressing the challenges faced by rapidly growing, global businesses. Paul brings proven management and leadership skills that are critical to us as a multi-product development organization. Paul has played a crucial role in the clinical development, launch or commercial marketing of more than 25 medications across a broad range of indications, including rare and orphan diseases. In his new role, Gene will continue to rely on his broad clinical and regulatory background and will focus his directly relevant experience with the FDA and demonstrated product strategy expertise on the development of our ongoing portfolio strategy,” added Mr. Lewis. Insmed Incorporated is a global biopharmaceutical company focused on the unmet needs of patients with rare diseases. The company is advancing a global phase 3 clinical study of ARIKAYCE® (liposomal amikacin for inhalation) for adult patients with treatment refractorynontuberculous mycobacteria (NTM) lung disease caused by Mycobacterium avium complex (MAC), which is a rare and often chronic infection that is capable of causing irreversible lung damage and can be fatal. There are currently no approved inhaled products specifically indicated for the treatment of refractory NTM lung disease caused by MAC in the United States or the European Union. Insmed's earlier-stage clinical pipeline includes INS1007, a novel oral reversible inhibitor of DPP1 with therapeutic potential in non-cystic fibrosis bronchiectasis, and INS1009, an inhaled nanoparticle formulation of a treprostinil prodrug that may offer a differentiated product profile for rare pulmonary disorders, including pulmonary arterial hypertension. For more information, visit www.insmed.com. "Insmed" and "ARIKAYCE" are the company's trademarks. All other trademarks, trade names or service marks appearing in this press release are the property of their respective owners. This press release contains forward looking statements.  "Forward-looking statements," as that term is defined in the Private Securities Litigation Reform Act of 1995, are statements that are not historical facts and involve a number of risks and uncertainties.  Words herein such as "may," "will," "should," "could," "would," "expects," "plans," "anticipates," "believes," "estimates," "projects," "predicts," "intends," "potential," "continues," and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) may identify forward-looking statements. The forward-looking statements in this press release are based upon the company's current expectations and beliefs, and involve known and unknown risks, uncertainties and other factors, which may cause the company's actual results, performance and achievements and the timing of certain events to differ materially from the results, performance, achievements or timing discussed, projected, anticipated or indicated in any forward-looking statements. Such factors include, among others: uncertainties in the research and development of our existing product candidates, including due to delays in patient enrollment or failure of our preclinical studies or clinical trials to satisfy pre-established endpoints; failure to develop, or to license for development, additional product candidates, including a failure to attract experienced third party collaborators; failure to obtain, or delays in obtaining, regulatory approval from the United States Food and Drug Administration, the European Medicines Agency, and other regulatory authorities for our product candidates or their delivery devices, including due to insufficient clinical data or selection of endpoints that are not satisfactory to regulators; failure of third parties on which we are dependent to conduct our clinical trials and to manufacture sufficient quantities of our product candidates for clinical or commercial needs; failure to comply with license agreements that are critical for our product development, including our license agreements with PARI Pharma GmbH and AstraZeneca AB; lack of safety and efficacy of our product candidates; inaccuracies in our estimate of the size of the potential markets for our product candidates; failure to maintain regulatory approval for our product candidates, once received, due to a failure to satisfy post-approval regulatory requirements, such as the need for post-clinical trials; uncertainties in the rate and degree of market acceptance of product candidates, if approved; uncertainties in the timing, scope and rate of reimbursement for our product candidates; competitive developments affecting our product candidates; inaccurate estimates regarding our future capital requirements, including those necessary to fund milestone payments or royalties owed to third parties; inability to repay our existing indebtedness or to obtain additional financing when needed; failure to obtain, protect and enforce our patents and other intellectual property; inability to create an effective direct sales and marketing infrastructure or to partner with a third party that offers such an infrastructure for distribution of our product candidates; the cost and potential reputational damage resulting from litigation to which we are a party, including, without limitation, the class action lawsuit pending against us; failure to comply with the laws and regulations that impact our business; loss of key personnel; and changes in laws and regulations applicable to our business, including those related to pricing and reimbursement of our product candidates.  For additional information about the risks and uncertainties that may affect our business, please see the factors discussed in Item 1A, "Risk Factors," in the company's Annual Report on Form 10-K for the year ended December 31, 2016. The company cautions readers not to place undue reliance on any such forward-looking statements, which speak only as of the date of this press release. The company disclaims any obligation, except as specifically required by law and the rules of the Securities and Exchange Commission, to publicly update or revise any such statements to reflect any change in expectations or in events, conditions or circumstances on which any such statements may be based, or that may affect the likelihood that actual results will differ from those set forth in the forward-looking statements.


News Article | May 15, 2017
Site: globenewswire.com

Dr. Yaron Daniely to Step Down as Chief Executive Officer, Effective May 31, 2017 Dr. Daniely to Remain on Board of Directors and be Appointed Chairman TEL AVIV, Israel, May 15, 2017 (GLOBE NEWSWIRE) -- Alcobra Ltd. (Nasdaq:ADHD), an emerging pharmaceutical company focused on the development of new medications to treat significant unmet clinical needs, today announced that Dr. Yaron Daniely will be stepping down on May 31, 2017 as President and Chief Executive Officer to become the Chief Executive Officer of Yissum, the technology transfer company of the Hebrew University in Jerusalem, Israel. David Baker, currently Alcobra’s Chief Commercial Officer, will assume the position of interim CEO. Dr. Daniely will remain on the Board of Directors of Alcobra and will be actively involved in ensuring a seamless transition of duties and responsibilities.  The Company’s Board of Directors also announced that it has appointed Dr. Daniely as Chairman of the Board of Directors, effective June 1, 2017. “Dr. Daniely has been a driven and passionate leader for the company and we thank him for years of service as CEO and wish him all the best as CEO of Yissum.  We are grateful that he will continue to provide leadership as chairman of Alcobra and actively support the CEO transition,” said Howard B. Rosen, current Chairman of Alcobra. “Alcobra has significantly advanced a strategic alternatives process to review opportunities to create value for all of our shareholders.  Further, we have made substantial progress in reducing overall costs and expenses.  We look forward to updating shareholders on future developments.” “It has been an honor to lead Alcobra over the past seven years,” said Dr. Yaron Daniely. “I’m proud of what we’ve accomplished, and believe the company has made significant progress over the past few months to advance potential value creation.  I have full confidence in David and the rest of the management team and look forward to an ongoing role at the board level in shaping the future of Alcobra.” Mr. Baker said, “I am proud to succeed Dr. Daniely as Alcobra’s interim CEO. Yaron is an exceptional leader and mentor.  I look forward to working with the rest of Alcobra’s team to continue delivering on the company’s strategic objectives.” Alcobra continues its established process to explore options for creating shareholder value. The company is currently exploring strategic alternatives, which may include partnership or monetization opportunities for the company’s proprietary product candidates – MDX and/or ADAIR, as well as partnering, licensing, M&A opportunities or other transactions to further develop the company’s pipeline and drug- development capabilities for the benefit of increasing shareholder value. About David Baker Mr. Baker joined Alcobra in 2014 as Chief Commercial Officer. Prior to joining Alcobra, he worked at Shire Pharmaceuticals for 10 years, including as Vice President of Commercial Strategy and New Business in the Neuroscience Business Unit. In that role, Mr. Baker led the commercial assessment of neuroscience licensing opportunities, managed commercial efforts on pipeline CNS products, and led the long term strategic planning process. Previously, he served as Global General Manager for Shire’s Vyvanse® where he led the launch of Vyvanse and led global expansion efforts including successful establishment of a partnership in Japan and launches in Canada and Brazil. Prior to that, Mr. Baker served as Vice President of Marketing for all of Shire's ADHD products. From 1990 - 2004, Mr. Baker worked at Merck & Co., where he held positions of increasing responsibility in marketing, sales, market research, and business development. In addition to his knowledge and experience with CNS medications, Mr. Baker's expertise includes therapeutics for osteoporosis, migraine, and hyperlipidemia. He has been directly involved with the marketing of five medications with annual sales in excess of $1 billion each. Mr. Baker graduated Magna Cum Laude with a bachelor's degree in Economics and Computer Science from Duke University. He earned a Master of Business Administration in Marketing from Duke's Fuqua School of Business. About Alcobra Alcobra Ltd. is an emerging pharmaceutical company primarily focused on the development and commercialization of medications to treat significant unmet medical needs. For more information, please visit the company's website, www.alcobra-pharma.com, the content of which is not incorporated herein by reference. Forward Looking Statements This press release contains forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995 and other Federal securities laws. Because such statements deal with future events and are based on the Company’s current expectations, they are subject to various risks and uncertainties and actual results, performance or achievements of the Company could differ materially from those described in or implied by the statements in this press release. For example, forward-looking statements include statements regarding updating shareholders on future developments, creating shareholder value and exploring strategic alternatives. The forward-looking statements contained or implied in this press release are subject to risks and uncertainties, including those discussed under the heading “Risk Factors” in the Company’s Annual Report on Form 20-F for the fiscal year ended December 31, 2016, filed with the Securities and Exchange Commission (SEC) and in subsequent filings with the SEC. Except as otherwise required by law, the Company disclaims any intention or obligation to update or revise any forward-looking statements, which speak only as of the date they were made, whether as a result of new information, future events or circumstances or otherwise.


News Article | May 15, 2017
Site: globenewswire.com

Dr. Yaron Daniely to Step Down as Chief Executive Officer, Effective May 31, 2017 Dr. Daniely to Remain on Board of Directors and be Appointed Chairman TEL AVIV, Israel, May 15, 2017 (GLOBE NEWSWIRE) -- Alcobra Ltd. (Nasdaq:ADHD), an emerging pharmaceutical company focused on the development of new medications to treat significant unmet clinical needs, today announced that Dr. Yaron Daniely will be stepping down on May 31, 2017 as President and Chief Executive Officer to become the Chief Executive Officer of Yissum, the technology transfer company of the Hebrew University in Jerusalem, Israel. David Baker, currently Alcobra’s Chief Commercial Officer, will assume the position of interim CEO. Dr. Daniely will remain on the Board of Directors of Alcobra and will be actively involved in ensuring a seamless transition of duties and responsibilities.  The Company’s Board of Directors also announced that it has appointed Dr. Daniely as Chairman of the Board of Directors, effective June 1, 2017. “Dr. Daniely has been a driven and passionate leader for the company and we thank him for years of service as CEO and wish him all the best as CEO of Yissum.  We are grateful that he will continue to provide leadership as chairman of Alcobra and actively support the CEO transition,” said Howard B. Rosen, current Chairman of Alcobra. “Alcobra has significantly advanced a strategic alternatives process to review opportunities to create value for all of our shareholders.  Further, we have made substantial progress in reducing overall costs and expenses.  We look forward to updating shareholders on future developments.” “It has been an honor to lead Alcobra over the past seven years,” said Dr. Yaron Daniely. “I’m proud of what we’ve accomplished, and believe the company has made significant progress over the past few months to advance potential value creation.  I have full confidence in David and the rest of the management team and look forward to an ongoing role at the board level in shaping the future of Alcobra.” Mr. Baker said, “I am proud to succeed Dr. Daniely as Alcobra’s interim CEO. Yaron is an exceptional leader and mentor.  I look forward to working with the rest of Alcobra’s team to continue delivering on the company’s strategic objectives.” Alcobra continues its established process to explore options for creating shareholder value. The company is currently exploring strategic alternatives, which may include partnership or monetization opportunities for the company’s proprietary product candidates – MDX and/or ADAIR, as well as partnering, licensing, M&A opportunities or other transactions to further develop the company’s pipeline and drug- development capabilities for the benefit of increasing shareholder value. About David Baker Mr. Baker joined Alcobra in 2014 as Chief Commercial Officer. Prior to joining Alcobra, he worked at Shire Pharmaceuticals for 10 years, including as Vice President of Commercial Strategy and New Business in the Neuroscience Business Unit. In that role, Mr. Baker led the commercial assessment of neuroscience licensing opportunities, managed commercial efforts on pipeline CNS products, and led the long term strategic planning process. Previously, he served as Global General Manager for Shire’s Vyvanse® where he led the launch of Vyvanse and led global expansion efforts including successful establishment of a partnership in Japan and launches in Canada and Brazil. Prior to that, Mr. Baker served as Vice President of Marketing for all of Shire's ADHD products. From 1990 - 2004, Mr. Baker worked at Merck & Co., where he held positions of increasing responsibility in marketing, sales, market research, and business development. In addition to his knowledge and experience with CNS medications, Mr. Baker's expertise includes therapeutics for osteoporosis, migraine, and hyperlipidemia. He has been directly involved with the marketing of five medications with annual sales in excess of $1 billion each. Mr. Baker graduated Magna Cum Laude with a bachelor's degree in Economics and Computer Science from Duke University. He earned a Master of Business Administration in Marketing from Duke's Fuqua School of Business. About Alcobra Alcobra Ltd. is an emerging pharmaceutical company primarily focused on the development and commercialization of medications to treat significant unmet medical needs. For more information, please visit the company's website, www.alcobra-pharma.com, the content of which is not incorporated herein by reference. Forward Looking Statements This press release contains forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995 and other Federal securities laws. Because such statements deal with future events and are based on the Company’s current expectations, they are subject to various risks and uncertainties and actual results, performance or achievements of the Company could differ materially from those described in or implied by the statements in this press release. For example, forward-looking statements include statements regarding updating shareholders on future developments, creating shareholder value and exploring strategic alternatives. The forward-looking statements contained or implied in this press release are subject to risks and uncertainties, including those discussed under the heading “Risk Factors” in the Company’s Annual Report on Form 20-F for the fiscal year ended December 31, 2016, filed with the Securities and Exchange Commission (SEC) and in subsequent filings with the SEC. Except as otherwise required by law, the Company disclaims any intention or obligation to update or revise any forward-looking statements, which speak only as of the date they were made, whether as a result of new information, future events or circumstances or otherwise.


News Article | May 15, 2017
Site: globenewswire.com

Dr. Yaron Daniely to Step Down as Chief Executive Officer, Effective May 31, 2017 Dr. Daniely to Remain on Board of Directors and be Appointed Chairman TEL AVIV, Israel, May 15, 2017 (GLOBE NEWSWIRE) -- Alcobra Ltd. (Nasdaq:ADHD), an emerging pharmaceutical company focused on the development of new medications to treat significant unmet clinical needs, today announced that Dr. Yaron Daniely will be stepping down on May 31, 2017 as President and Chief Executive Officer to become the Chief Executive Officer of Yissum, the technology transfer company of the Hebrew University in Jerusalem, Israel. David Baker, currently Alcobra’s Chief Commercial Officer, will assume the position of interim CEO. Dr. Daniely will remain on the Board of Directors of Alcobra and will be actively involved in ensuring a seamless transition of duties and responsibilities.  The Company’s Board of Directors also announced that it has appointed Dr. Daniely as Chairman of the Board of Directors, effective June 1, 2017. “Dr. Daniely has been a driven and passionate leader for the company and we thank him for years of service as CEO and wish him all the best as CEO of Yissum.  We are grateful that he will continue to provide leadership as chairman of Alcobra and actively support the CEO transition,” said Howard B. Rosen, current Chairman of Alcobra. “Alcobra has significantly advanced a strategic alternatives process to review opportunities to create value for all of our shareholders.  Further, we have made substantial progress in reducing overall costs and expenses.  We look forward to updating shareholders on future developments.” “It has been an honor to lead Alcobra over the past seven years,” said Dr. Yaron Daniely. “I’m proud of what we’ve accomplished, and believe the company has made significant progress over the past few months to advance potential value creation.  I have full confidence in David and the rest of the management team and look forward to an ongoing role at the board level in shaping the future of Alcobra.” Mr. Baker said, “I am proud to succeed Dr. Daniely as Alcobra’s interim CEO. Yaron is an exceptional leader and mentor.  I look forward to working with the rest of Alcobra’s team to continue delivering on the company’s strategic objectives.” Alcobra continues its established process to explore options for creating shareholder value. The company is currently exploring strategic alternatives, which may include partnership or monetization opportunities for the company’s proprietary product candidates – MDX and/or ADAIR, as well as partnering, licensing, M&A opportunities or other transactions to further develop the company’s pipeline and drug- development capabilities for the benefit of increasing shareholder value. About David Baker Mr. Baker joined Alcobra in 2014 as Chief Commercial Officer. Prior to joining Alcobra, he worked at Shire Pharmaceuticals for 10 years, including as Vice President of Commercial Strategy and New Business in the Neuroscience Business Unit. In that role, Mr. Baker led the commercial assessment of neuroscience licensing opportunities, managed commercial efforts on pipeline CNS products, and led the long term strategic planning process. Previously, he served as Global General Manager for Shire’s Vyvanse® where he led the launch of Vyvanse and led global expansion efforts including successful establishment of a partnership in Japan and launches in Canada and Brazil. Prior to that, Mr. Baker served as Vice President of Marketing for all of Shire's ADHD products. From 1990 - 2004, Mr. Baker worked at Merck & Co., where he held positions of increasing responsibility in marketing, sales, market research, and business development. In addition to his knowledge and experience with CNS medications, Mr. Baker's expertise includes therapeutics for osteoporosis, migraine, and hyperlipidemia. He has been directly involved with the marketing of five medications with annual sales in excess of $1 billion each. Mr. Baker graduated Magna Cum Laude with a bachelor's degree in Economics and Computer Science from Duke University. He earned a Master of Business Administration in Marketing from Duke's Fuqua School of Business. About Alcobra Alcobra Ltd. is an emerging pharmaceutical company primarily focused on the development and commercialization of medications to treat significant unmet medical needs. For more information, please visit the company's website, www.alcobra-pharma.com, the content of which is not incorporated herein by reference. Forward Looking Statements This press release contains forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995 and other Federal securities laws. Because such statements deal with future events and are based on the Company’s current expectations, they are subject to various risks and uncertainties and actual results, performance or achievements of the Company could differ materially from those described in or implied by the statements in this press release. For example, forward-looking statements include statements regarding updating shareholders on future developments, creating shareholder value and exploring strategic alternatives. The forward-looking statements contained or implied in this press release are subject to risks and uncertainties, including those discussed under the heading “Risk Factors” in the Company’s Annual Report on Form 20-F for the fiscal year ended December 31, 2016, filed with the Securities and Exchange Commission (SEC) and in subsequent filings with the SEC. Except as otherwise required by law, the Company disclaims any intention or obligation to update or revise any forward-looking statements, which speak only as of the date they were made, whether as a result of new information, future events or circumstances or otherwise.


Regenerative Medicine Market is estimated at $20.07 billion in 2015 and is projected to reach $101.3 billion by 2022 growing at a CAGR of 26.0% from 2015 to 2022Pune , India - April 24, 2017 /MarketersMedia/ — Regenerative Medicine Industry Description According to Stratistics MRC, the Regenerative Medicine Market is estimated at $20.07 billion in 2015 and is projected to reach $101.3 billion by 2022 growing at a CAGR of 26.0% from 2015 to 2022. Growing research applications, growing demand in tissue engineering, biomaterials and stem cell therapy systems are some of the factors driving the market growth. However, high cost associated with biomaterials will be a major factor to restrict the market growth. The stem cells application and advancements in nanotechnology will further drive the market over the forecast period. Gene therapies segment is expected to be the fastest emerging technology due to tremendous potential of gene therapy in minimizing immune rejections, which commonly occur after transplantations. Asia-Pacific would be the fastest growing region for regenerative medicine market. Europe and North America together accounted for over 3/4th of the market revenue and anticipated to be most profitable regional market. Some of the key players in the market include Shire Pharmaceuticals, Advanced Cell Technology, Inc, Genzyme, Athersys, Inc., Kinetic Concepts, Inc., NuVasive Inc., Stem cells, Inc., Cytori Therapeutics, Inc., Cytomedix Inc., Mesoblast Ltd. , Zimmer Holdings, Inc., Orthofix, DePuy Synthes Inc., Cell Medica and CryoLife. Request for Sample Report @ https://www.wiseguyreports.com/sample-request/456590-regenerative-medicine-global-market-outlook-2015-2022 Technologies Covered: • Small Molecules and Biologics • Gene Therapy • Cell Therapy Applications Covered: • Dermatology • Cardiovascular Disorders • Central Nervous System (CNS) • Orthopedic • Dental • Other applications o Autoimmune Diseases o Muscle Regeneration o Ocular Diseases o Internal organ regeneration Leave a Query @ https://www.wiseguyreports.com/enquiry/456590-regenerative-medicine-global-market-outlook-2015-2022 Regions Covered: • North America o US o Canada o Mexico • Europe o Germany o France o Italy o UK o Spain o Rest of Europe • Asia Pacific o Japan o China o India o Australia o New Zealand o Rest of Asia Pacific • Rest of the World o Middle East o Brazil o Argentina o South Africa o Egypt What our report offers: - Market share assessments for the regional and country level segments - Market share analysis of the top industry players - Strategic recommendations for the new entrants - Market forecasts for a minimum of 7 years of all the mentioned segments, sub segments and the regional markets - Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations) - Strategic recommendations in key business segments based on the market estimations - Competitive landscaping mapping the key common trends - Company profiling with detailed strategies, financials, and recent developments - Supply chain trends mapping the latest technological advancements Buy now @ https://www.wiseguyreports.com/checkout?currency=one_user-USD&report_id=456590 Continued... Contact Us: Sales@Wiseguyreports.Com Ph: +1-646-845-9349 (US) Ph: +44 208 133 9349 (UK) Contact Info:Name: NORAH TRENTEmail: sales@wiseguyreports.comOrganization: WISE GUY RESEARCH CONSULTANTS PVT LTDAddress: Office No. 528, Amanora Chambers Magarpatta Road, Hadapsar Pune - 411028Phone: +91 841 198 5042Source URL: http://marketersmedia.com/regenerative-medicine-market-2017-global-share-trend-and-opportunities-forecast-to-2022/189453For more information, please visit https://www.wiseguyreports.com/sample-request/456590-regenerative-medicine-global-market-outlook-2015-2022Source: MarketersMediaRelease ID: 189453


News Article | February 28, 2017
Site: www.eurekalert.org

Infants with a genetic polymorphism of the serotonin transporter gene may be more susceptible to a psychosocial intervention designed to promote maternal-infant attachment in South Africa, according to a study in PLOS Medicine. In a study led by Mark Tomlinson from Stellenbosch University, South Africa, with lead author Barak Morgan from the University of Cape Town, South Africa and colleagues, data from a randomized controlled trial were reanalysed in light of new genetic data. In the study, researchers reanalysed data from a randomized controlled trial that was originally published in 2009. This had found that infants whose mothers were visited by lay community workers to provide support and guidance in parenting were significantly more likely to be securely attached to their primary caregiver after 18 months. Using genetic data collected from 220 participants when they were 13 years of age (approximately half of those who participated in the original trial) the researchers were able to compare attachment rates for participants with different polymorphisms of the serotonin transporter gene. Individuals with the short form of the gene, which is involved in nerve signalling in the brain, have previously been found to be sensitive to psychosocial interventions. The researchers found that, for those with the short allele of the serotonin transporter gene, the probability of secure attachment being observed for those who received the intervention was 84% (95% CI [73%, 94%]), compared to 58% (95% CI [43%, 72%]) in the control group. For those with two copies of the long allele of the serotonin transporter gene, the probability of secure attachment being observed for those who received the intervention was 70% (95% CI [59%, 81%]), compared to 71% (95% CI [60%, 82%]) of infants in the control group. The researchers note, "[b]eyond illuminating the role of genetic differential susceptibility in early childhood development, the current finding also speaks to a fundamental issue in the quest to understand and mitigate the developmental effects of poverty through psychosocial intervention. The near large effect size reported here for the intervention in children with susceptible genotypes [...] is at variance with the general conclusion that psychosocial interventions in the context of poverty produce only small to medium effect sizes [...] Without taking account of genetic susceptibility, it is possible that other intervention studies have, at least in some subpopulations, underestimated the impact of their interventions, as we originally did. By the same token [...] other studies might also have underestimated the negative impact on susceptible subpopulations of not receiving an intervention [...] In short, averaging outcomes across all participants may well lead to an invalid conclusion about the efficacy of an intervention. The researchers also note, "[a]n important limitation of this study is that we were not able to follow-up all cases of the individuals from the original trial, and there were missing data for attachment and genotype. In total, our primary analysis included 49% (220/449) of the original sample of children whose mothers were randomized to treatment and control conditions. Although the intervention and control groups were highly similar in our follow-up sample, and the follow-up sample was generally very similar to the original sample, there was some evidence of selective loss to follow-up on two variables [...] This means that randomization within our follow-up subsample may have been imperfect. Attribution of the primary outcome to causal effects of treatment in the present subsample should therefore be treated with caution. This study was supported by a grant from Grand Challenges Canada, grant reference #0066-03). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. MT is a member of the Editorial Board of PLOS Medicine. PF received an honorarium for providing a workshop on attachment at the Meeting of Minds Conference, organised by Shire Pharmaceuticals. Morgan B, Kumsta R, Fearon P, Moser D, Skeen S, Cooper P, et al. (2017) Serotonin transporter gene (SLC6A4) polymorphism and susceptibility to a home-visiting maternal-infant attachment intervention delivered by community health workers in South Africa: Reanalysis of a randomized controlled trial. PLoS Med 14(2): e1002237. doi:10.1371/journal.pmed.1002237 Global Risk Governance Program, Department of Public Law, University of Cape Town, Rondebosch, South Africa NRF Centre of Excellence in Human Development, DVC Research Office, University of Witwatersrand, Johannesburg, South Africa Neonatal Unit, Department of Women's and Children's Health, Karolinska Institute, Stockholm, Sweden Department of Genetic Psychology, Faculty of Psychology, Ruhr University Bochum, Bochum, Germany Research Department of Clinical, Educational and Health Psychology, Faculty of Brain Sciences, University College London, London, United Kingdom Department of Psychology, Stellenbosch University, Stellenbosch, South Africa School of Psychology and Clinical Language Sciences, University of Reading, Reading, United Kingdom Department of Psychology, University of Cape Town, Rondebosch, South Africa Department of Psychology, Western University, London, Ontario, Canada IN YOUR COVERAGE PLEASE USE THIS URL TO PROVIDE ACCESS TO THE FREELY AVAILABLE PAPER: http://journals.


News Article | February 12, 2017
Site: www.theguardian.com

This year marks the 50th anniversary of Harold Wilson’s memorable broadcast following his government’s devaluation of the pound. “It does not mean, of course, that the pound here in Britain, in your pocket or purse or in your bank, has been devalued,” he said. This, depending on your preference for modern or traditional language, is either a) an alternative fact or b) a brazen fib. Even economists weren’t dozy enough to miss that the fact that the same pound paid for Britain’s imports, meaning that after devaluation it bought fewer goods, and therefore domestic prices would go up. So unless wages rose by as much, the pound in your pocket was worth less. It is similar today, where it is not just increases in the price of Marmite that bean counters want to justify by pointing to weaker sterling – as we will be reminded this week. On Tuesday, we will get the latest inflation data for January when, after a long run of near-zero inflation last year, it is expected to hit a new two-and-a-half-year high of 1.9%. So what does it all mean for the pound in our pockets? Well, pay (data also updated this week) is still thought to be outstripping living costs – at least for now. However, there are fears that wage growth will slow, just as inflation is picking up, and as Wilson quickly discovered, folk tend to notice that. There are numbers from engine maker Rolls-Royce, plus full-year results from Shire Pharmaceuticals, which last month agreed to a $350m settlement over US claims that it used “kickbacks and other unlawful methods” to induce doctors to prescribe one of its drugs. The US Department of Justice says Shire staff unlawfully “induced clinics and physicians with lavish dinners, drinks, entertainment and travel” as well as “unwarranted payments” for speaking engagements and cash credits and rebates to boost sales. Anyway, if there is a good time to get caught paying bungs, this wasn’t it, what with US president Donald Trump already hinting that he may have pharmaceuticals companies in his sights over drug pricing. All of which means that the company will try to talk about financials this week, with the City expecting a big boost to sales this year due to currency movements but also as a result of the integration of recent acquisitions. Time to polish up your curriculum vitae to take advantage of the new opportunities Brexit presents. First up are exciting vacancies being advertised for chief trade negotiation advisers where (depending on your point of view) you can either prepare the UK for a new era of dynamic international trade, or attempt to save the country from itself. The successful candidates can earn £160,000 a year, assuming they can demonstrate “extensive experience of overseeing and leading complex and large-scale trade negotiations on an international basis” – which could be a stretch, given that the EU has been doing all that, leaving few Brits with that experience (unless they served under Ted Heath). Still, no matter. No one is likely to kick up a fuss if the talent is imported. Meanwhile, public sector headhunters will also be out in force, searching for a new member of the Bank of England’s monetary policy committee, following last week’s announcement of Kristin Forbes’s decision to turn down a second term and return to her native US. City gossips suggest that the Bank will prefer that another woman to replace Forbes, in an effort to make sure the committee isn’t viewed as even less diverse.


News Article | February 15, 2017
Site: www.businesswire.com

BASEL, Switzerland--(BUSINESS WIRE)--Therachon AG, a biotechnology company focused on rare genetic diseases, announced today the strengthening of its Board of Directors and executive management team. Hans Schikan, Pharm.D., will the join the Board as a non-executive director. Richard Porter, Ph.D., is announced as the Chief Operating Officer and Jeffrey Stavenhagen, Ph.D. as Vice President of Biology. “I am delighted to have Drs. Schikan, Porter and Stavenhagen join our team,” said Luca Santarelli, M.D., Therachon’s Chief Executive Officer and Director. “The addition of these three tenured biopharmaceutical executives extends and deepens our scientific and business expertise. With their experience and successful track record, I am confident that we will be able to harness the full therapeutic potential of our drug candidate, TA-46, for children suffering from achondroplasia.” “I am thrilled to welcome these three industry leaders to our Board and management team,” said Thomas Woiwode, Ph.D., Managing Director at Versant Ventures and Chairman of the Board at Therachon. “Hans, Richard and Jeffrey understand the potential and hope Therachon brings to patients suffering from rare, genetic diseases. Under Luca’s leadership and with the recent completion of our $40 million Series A financing, Therachon is now well positioned to accelerate TA-46 into the clinic.” Hans Schikan currently serves as Chairman at Asceneuron (Switzerland), Complix (Belgium) and InteRNA (Netherlands), and is a non-executive director at Hansa Medical (Sweden), Swedish Orphan Biovitrum (Sweden), Wilson Therapeutics (Sweden) and Dutch Top Sector Life Sciences & Health (Netherlands). Previously, he was the CEO of Prosensa, which used RNA modulation to treat rare diseases such as Duchenne muscular dystrophy (DMD). While at Prosensa, he oversaw the M&A transaction with BioMarin for up to $840 million. Prior to that, he held senior strategic and commercial positions at Genzyme and Organon. Hans Schikan received his Pharm.D. from the University of Utrecht (Netherlands). Richard Porter brings over 20 years of experience working across multiple therapeutic areas in the pharmaceutical and biotech industries. He spent over 14 years at Roche in positions of increasing responsibility, most recently as the Global Head of Operations Management for Neuroscience Ophthalmology and Rare Diseases. He has also served as a Product General Manager in the Emerging Business Unit at Shire Pharmaceuticals, and held scientific leadership positions at Vernalis and ASTRA. He has brought multiple projects through development and brings extensive experience at both an operational and strategic level. He received his Ph.D. from the University of Southampton and completed his postdoctoral training at the University of Oxford (U.K.) and at the University of Rochester (U.S.). Jeffrey Stavenhagen brings 20 years of scientific leadership experience in both the U.S. and Europe using emerging technology platforms for the development of novel biologics. He most recently was a Senior Director at Lundbeck (Denmark) and led their global biologics program to treat CNS diseases. Prior to that, he served as Director, Molecular Immunology at Amplimmune and held roles of increasing responsibility at MacroGenics. Dr. Stavenhagen started his career as an assistant professor at the University of Dayton in the Department of Biology. He received his Ph.D. in molecular biology from Columbia University and conducted Post-Doctoral research at the Fred Hutchinson Cancer Research Center in Seattle, Washington. Therachon is a global biotechnology company focused on developing medicines for rare, genetic diseases that currently have no available treatments. The company’s lead pipeline candidate, TA-46, is a novel protein therapy in development for achondroplasia, the most common form of short-limbed dwarfism. This rare genetic condition affects about one in 25,000 children and is caused by a genetic mutation of the FGFR3 receptor, which stunts child bone growth. Therachon is committed to translating the promise of its science into new treatments for patients with high unmet medical needs. For more information, visit www.therachon.com.

Loading Shire Pharmaceuticals collaborators
Loading Shire Pharmaceuticals collaborators