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Kavitha Kamath B.,Shimoga Institute of Medical science
Journal of Clinical and Diagnostic Research | Year: 2015

A rare variation was seen in the arterial supply of liver and gall bladder during dissection of an adult female cadaver. The right hepatic artery was having a tortuous course with double loops and cystic artery was arising from the distal loop within the hepatobiliary triangle. There was an accessory cystic artery arising from the superior pancreaticoduodenal artery outside the hepatobiliary triangle which ascended anterior to the common bile duct and cystic duct towards the gall bladder. The knowledge of these vascular variations is very much essential owing to increase in surgical interventions involving the biliary tract. Recognition of such vascular variations is essential for laparoscopic surgeons to reduce complications like uncontrolled intraoperative bleeding, iatrogenic extrahepatic biliary injuries and conversion to open cholecystectomy. This report emphasizes the necessity of all surgeons being well aware of vascular variations and anomalies to be able to accomplish safe and uneventful hepatobiliary surgeries. © 2015, Journal of Clinical and Diagnostic Research. All rights reserved.

Kumar D.B.,Shimoga Institute of Medical science | Raghupathi A.R.,Bangalore Medical College and Research Institute
Basic and Applied Pathology | Year: 2012

Background and aim: A study was carried out to analyze the presentation, to identify the causes and to find out the bone marrow morphology in cases of pancytopenia. Pancytopenia was an indication for bone marrow examination in 48 out of a total of 100 cases (48%) for which a bone marrow examination was requested. Methods: The data regarding the various signs and symptoms, the causes and the bone marrow findings were obtained and analyzed using simple statistical methods. All age groups were included for the study. Results: Generalized weakness (70.83%) was the commonest symptom and pallor (45.83%) was the predominant sign. Anisocytosis (79.1%) was the most important peripheral blood finding in pancytopenic patients followed by microcytosis (52.08%). The commonest cause of pancytopenia in the present study was hypoplastic marrow (33.33%), followed by normoblastic erythroid hyperplasia (27.08%), megaloblastic marrow (18.75%), and myelodysplastic syndrome (8.33%). Normal bone marrow and dry tap accounted for three cases each (6.25%). Of the various cases of myelodysplastic syndrome, one was refractory anemia; two were refractory cytopenia with multilineage dysplasia and one myelodysplastic syndrome unclassified. Dry tap was seen in three cases of pancytopenia. Bone marrow biopsy was done in one, which showed features of myelofibrosis. Conclusions: A thorough evaluation of the pancytopenic patients is necessary as it has varied causes. © 2012 The Korean Society for Cytopathology, The Korean Society for Legal Medicine, The Korean Society of Oral and Maxillofacial Pathology, The Korean Society of Pathologists, The Korean Society of Toxicological Pathology, The Korean Society of Veterinary Pathology and Blackwell Publishing Asia Pty Ltd.

Veeresh M.R.,Shimoga Institute of Medical science
Journal of South India Medicolegal Association | Year: 2012

Many women in developing countries are subjected to various forms of pain and suffering, more during the age in which they are more fertile and thrust with newer responsibilities at home. They are battered, bruised, mutilated and killed. Others are driven to commit suicide because of intolerable suffering. In the present study, 438 such cases of harassment to women of reproductive age (13-45 years) who visited the District Hospital, Belgaum, South India and KLE Society's Hospital, Belgaum, and medicolegal cases autopsied at the District Hospital, Belgaum from January to December, 2001 were studied. Among them, 36% were physically assaulted, 32.4% consumed poisons, 22.6% sustained burns, 4.1% met with accidents, 1.4% were sexually assaulted and 0.5% underwent criminal abortion. The victims mainly consisted of married women, those in the age group of 13-34 years, school-educated women and those belonging to class II socioeconomic status. Alcohol was the precipitating factor in 31% of cases. © 2012 South India Medico-Legal Association. All rights reserved.

Koppad R.,Shimoga Institute of Medical science | Girish H.O.,Subbaiah Institute of Medical science & Research Center
Indian Journal of Public Health Research and Development | Year: 2015

Background: As we slowly advance into the 21st Century, we find that the challenges posed by non-communicable diseases (NCDs) present an imminent threat to people worldwide. The rapidly growing epidemic of non-communicable diseases is clearly related to changes in life styles. Objectives: 1) To study the socio-demographic factors of the region. 2) To assess the prevalence of behavioral risk factors for non-communicable diseases. Methods: Study Design: A Community-based cross-sectional descriptive study. Study participants: 2000 urban people of Davangere city, belonging to the age group 15-64 years. Study Period: 1st December 2008 and 30th November 2009 (1 year). Methodology: A multi-stage sampling method with households as sampling unit. Information on behavioral risk factors was obtained through standardized methods as recommended by the STEPS 1 survey guideline of the World Health Organization after modifying to suit the local requirement. Statistical analysis: Proportion and Chi-square test. Results: Total participants in the study were 2000, comprised of 1000 males’ and1000 females. High burden of NCD risk factors was observed among urban population: current smoking- 15.2% (Male-30.1%, Female-0.2%); current smokeless tobacco use -17.8% (Male- 28.8%, Female-6.8%); current alcohol use -17.5% (Male- 32.8%, Female-1.3%); physical inactivity -30.4% (Male- 17.6%, Female-43.3) Interpretation and Conclusions: Substantially high levels of the various behavioral risk factors in this urban population suggest an urgent need for adopting healthy life style modifications among the population in general. The increased risk observed among the younger generation for risk factors such as smoking, alcohol consumption calls for urgent corrective steps and measures for long-term monitoring of all major risk factors as well as the major chronic disease conditions. © 2015, Indian Journal of Public Health Research and Development. All rights reserved.

Hoskeri H.J.,Kuvempu University | Krishna V.,Kuvempu University | Kumar B.V.,Kuvempu University | Shridar A.H.,Kuvempu University | And 2 more authors.
Archives of Pharmacal Research | Year: 2012

The prophylactic effects of oleanolic acid (OA) isolated from chloroform extract (CE) of Flaveria trinervia against ethanol induced liver toxicity was investigated using rats. CE and OA at three different doses were tested by administering orally to the ethanol treated animals during the last week of the 7 weeks study. Silymarin was used as the standard reference. The substantially elevated serum enzymatic levels of serum glutamate oxaloacetate transaminase, glutamate pyruvate transaminase, alkaline phosphatase and bilirubin in ethanol treated animals were restored towards normalcy by treatment of CE and OA. In vivo antioxidant and in vitro free radical scavenging activities were also positive for all the three concentrations of CE and OA. However, OA at 150 mg/kg showed significant activity when compared to the other two doses. Biochemical observations in support with histopathological examinations revealed that CE and OA possess hepatoprotective action against ethanol induced hepatotoxicity in rats.

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