Shijiazhuang, China
Shijiazhuang, China

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Feng G.-L.,Hebei University of Science and Technology | Li Y.,Hebei University of Science and Technology | Geng L.-J.,Hebei University of Science and Technology | Zhang H.-L.,Hebei University of Science and Technology | And 2 more authors.
Synthetic Communications | Year: 2015

A series of trispiropyrrolidine bisoxindoles has been achieved via a three-component 1,3-dipolar cycloaddition reaction of 3-aryl-5-arylmethylenespiro[indole-3′,2-[1,3]thiazolane]-2′(1H),4-dione, isatin, and sarcosine in refluxing toluene, which produced the corresponding cycloadducts in good yields (79-88%). Their structures were determined by infrared, 1H and 13C NMR, elementary analysis, and single-crystal X-ray diffraction analysis, and the cycloaddtion reaction was found to be highly regio-and stereoselective. © 2015 Taylor and Francis Group, LLC.


Feng G.-L.,Hebei University of Science and Technology | Li Y.,Hebei University of Science and Technology | Chen S.-R.,Hebei University of Science and Technology | Geng L.-J.,Hebei University of Science and Technology | Wang K.-F.,Shijiazhuang Yonggangfangjong Co.
Journal of Chemical Research | Year: 2014

The synthesis of novel trispiropyrrolidine derivatives has been achieved by a one-pot, three-component 1,3-dipolar cycloaddition reaction of 3.aryl-5-arylmethylenespiro[indole-3′,2-[1,3]thiazolane]-2′(1H ),4-dione, isatin and sarcosine in refluxing toluene which produced the corresponding cycloadducts in good yields. The structures were determined by 1H NMR, IR and elementary analysis.

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