Sheffield Teaching Hospitals NHS Foundation Trust Sheffield

United Kingdom

Sheffield Teaching Hospitals NHS Foundation Trust Sheffield

United Kingdom
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Rowe F.,University of Liverpool | Wright D.,Altnagelvin Hospitals HHS Trust | Brand D.,NHS Ayrshire and Arran | Jackson C.,Royal United Hospitals Bath NHS Trust | And 18 more authors.
International Journal of Stroke | Year: 2011

Background Ocular causes of reading impairment following stroke include visual field loss, eye movement impairment and poor central vision. Non ocular causes may include cognitive errors or language impairment. Aim The purpose of this study was to identify all patients referred with suspected visual impairment who had reported reading difficulty to establish the prevalence of ocular and non ocular causes. Methods Prospective, multicentre, observation study with standardised referral and assessment forms across 21 sites. Visual assessment included visual acuity measurement, visual field assessment, ocular alignment, and movement and visual inattention assessment. Multicentre ethical approval and informed patient consent were obtained. Results A total of 915 patients were recruited, with a mean age of 69·18 years (standard deviation 14·19). Reading difficulties were reported by 177 patients (19·3%), with reading difficulty as the only symptom in 39 patients. Fifteen patients had normal visual assessment but with a diagnosis of expressive or receptive aphasia. Eight patients had alexia. One hundred and nine patients had visual field loss, 85 with eye movement abnormality, 27 with low vision and 39 patients with visual perceptual impairment. Eighty-seven patients had multiple ocular diagnoses with combined visual field, eye movement, low vision or inattention problems. All patients with visual impairment were given targeted treatment and/or advice including prisms, occlusion, refraction, low vision aids and scanning exercises. Conclusions Patients complaining of reading difficulty were mostly found to have visual impairment relating to low vision, eye movement or visual field loss. A small number were found to have non ocular causes of reading difficulty. Treatment or advice was possible for all patients with visual impairment. © 2011 The Authors. International Journal of Stroke © 2011 World Stroke Organization.


Benkner S.,University of Vienna | Borckholder C.,University of Vienna | Bubak M.,AGH University of Science and Technology | Kaniovskyi Y.,University of Vienna | And 5 more authors.
Proceedings - 27th International Conference on Advanced Information Networking and Applications Workshops, WAINA 2013 | Year: 2013

The VPH-Share project objective is to store, share, integrate, and link data, information, knowledge, and wisdom about the physiopathology of the human body to enable their reuse within the virtual physiological human community. Therefore, the projects develops a modular and generic data management platform on top of a distributed Cloud infrastructure. The data management platform enables the ontological annotation of VPH-relevant datasets, their provisioning in the Cloud, and supports different data integration approaches. In this paper we present the architecture and implementation of this VPH-Share Cloud and data management platform and we go into detail about two different data integration approaches: relational data mediation, which has been realized on top of a distributed data mediation engine, and semantic data integration, which is supported on the basis of the SPARQL federation extension. Both approaches are examined on top of a project-specific scenario executed in the VPH-Share Cloud environment. © 2013 IEEE.

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