Sharp Corporation is a Japanese multinational corporation that designs and manufactures electronic products. Headquartered in Abeno-ku, Osaka, Japan, Sharp employed 50,253 people worldwide as of March 2014. The company was founded in September 1912 and takes its name from one of its founder's first inventions, the Ever-Sharp mechanical pencil, which was invented by Tokuji Hayakawa in 1915. Sharp Corporation was previously the fifth-largest television manufacturer in the world, after Samsung, LG, Sony, and Panasonic. Since 2000, Sharp has heavily invested in LCD panel manufacturing plants; Kameyama in 2004, Sakai in 2009. The Sakai plant is still the only 10th generation LCD manufacturing plant on the globe and best fit for production of 60 inch or larger panels. However, the 2008 financial crisis and strong Yen significantly lowered world demand for Japanese LCD panels. Furthermore, the switch to digital TV broadcasting was virtually completed in Japan by the middle of 2011. Via Japanese government issued coupons for digital TV sets, consumers were encouraged to purchase digital TV sets until March 2011. This hit the Japanese LCD TV market, reducing it almost by half from 2010. All of those events strongly hit Sharp's LCD business. As the result, the Sakai LCD plant suffered a reduced operating rate until Fall 2012. 2012 was the 100th anniversary for Sharp but it announced the worst financial record in its history, with a loss of 376 billion yen in April 2012. In September, Sharp announced job cuts. In 2014, Sharp was able to stem losses and deliver a positive net income for its first quarter results. Wikipedia.
Sharp Corporation | Date: 2016-10-14
The present invention is directed to piperidinone carboxamide azaindane derivatives which are antagonists ofCGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
Sharp Corporation | Date: 2016-11-21
This invention describes an amidation process whereby perfluorinated amino acids can be activated and treated with an amine in the presence of a coupling agent and a pyridine derivative to yield amides, without loss of optical purity.
Sharp Corporation | Date: 2016-08-08
Compounds of Formula I: and their pharmaceutically acceptable salts are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.
Sharp Corporation | Date: 2016-08-11
A class of polycyclic compounds of general formula (I), of general formula (I), or of general formula (I), wherein Base^(1), Base^(2), Y, Y^(a), X^(a), X^(a1), X^(b), X^(b1), X^(c), X^(c1), X^(d), X^(d1), R^(1), R^(1a), R^(2), R^(2a), R^(3), R^(4), R^(4a), R^(5), R^(6), R^(6a), R^(7), R^(7a), R^(8), and R^(8a )are defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are processes for the synthesis and use of compounds.
Sharp Corporation | Date: 2016-09-16
Novel gyrase inhibitors and related compositions and methods are useful for impeding bacterial growth. Compounds of Formula (I), are disclosed: Formula (I), wherein Y is N or CH; Z is N or CR^(5); R^(5 )is H, a substituted or unsubstituted hydrocarbyl residue (1-3C) containing 0-2 heteroatoms selected from O, S and N, or is an inorganic residue; L is O, S, NR^(7), or CR^(8)R^(9); R^(7 )is H or C_(1-3 )alkyl; R^(8 )and R^(9 )are each independently H or C_(1-3 )alkyl; R^(2 )is H, a hydrocarbyl residue (1-40C) containing 0-10 heteroatoms selected from O, S and N optionally substituted with an inorganic residue; R^(4 )is H, an inorganic residue, or a hydrocarbyl residue (1-30C) containing 0-12 heteroatoms selected from O, S and N and containing 0-10 inorganic residues, wherein R^(5 )and R^(4 )together may join to form a fused ring; and R^(6 )is selected from the group consisting of H, C_(1-5 )alkyl, C_(2-5 )alkenyl, C_(2-5 )alkynyl, halo C_(1-5 )alkyl, halo C_(2-5 )alkenyl, halo C_(2-5 )alkynyl, C_(1-5 )hydroxyalkyl, C_(1-5 )alkyl chloride, C_(2-5 )alkenyl chloride, and C_(2-5 )alkynyl chloride; or a pharmaceutically-acceptable salt, ester, or prodrug thereof.
Sharp Corporation | Date: 2016-10-13
A paper feed apparatus includes a paper feeding portion that sends-out a paper placed in a paper placing tray, and is used in an image forming apparatus such as a multifunction machine. The paper feed apparatus comprises a first regulating portion and a second regulating portion that are arranged in the vicinity of a downstream side of a paper feeding position by the paper feeding portion. The first regulating portion is arranged outside a second width paper passage area to regulate a movement of a first width paper such as A4 paper placed in the paper placing tray toward a feeding direction. On the other hand, the second regulating portion is arranged inside the second width paper passage area to regulate a movement of a second width paper such as a name card placed in the paper placing tray toward a feeding direction. Since there are provided with the first regulating portion and the second regulating portion that are arranged outside and inside the second width paper passage area, the second width paper such as a name card can be adequately fed in addition to the first width paper such as A4 paper.
Sharp Corporation | Date: 2016-10-18
Provided is an electric apparatus including a reception unit (for example, hardware key) for receiving an instruction relating to functions of the electric apparatus and having operation states of a power conserving state in which power required for performing the functions thereof is limited and a normal state in which the power is not limited, wherein the reception unit may receive an instruction indicating a return to the normal state in the power conserving state and receive an instruction which is to be originally received in the normal state. When the reception unit receives the instruction, signals at different levels are output depending on the operation state and based on the signal to be output, a return signal relating to the return to the normal state or an execution signal relating to the execution of a function corresponding to the instruction received by the receiving signal is output.
Sharp Corporation | Date: 2016-09-23
The present invention provides antibodies and antigen-binding fragments thereof that bind to the antibody pembrolizumab (pembrolizumab). These antibodies are useful, for example, for use as positive controls in assays for detecting the presence of anti-drug antibodies in a sample, e.g., the blood of a patient who has been administered pembrolizumab.
Sharp Corporation | Date: 2016-11-03
Disclosed is an image forming apparatus including: a printing paper transport path in which printing paper is transported; a secondary transfer unit and a fixing section both disposed on the printing paper transport path; an open/close cover that, when opened, exposes the printing paper transport path in a main body of the apparatus; a pressure roller, disposed in the fixing section, that presses the printing paper on a side thereof facing the open/close cover against the printing paper transport path; and cooling fans that cool down the pressure roller, wherein the secondary transfer unit and the cooling fans are attached to the open/close cover and disposed at such positions that the secondary transfer unit and the cooling fans move following overlapping paths when the open/close cover is opened/closed.
Sharp Corporation | Date: 2016-10-11
A light-emitting device capable of ensuring an electric connection between a light-emitting element and an electrode without generating any problem in practical use, by both connecting methods with a solder and a connector, and a lighting device provided with the light-emitting device are provided. The light-emitting device according to the present invention has a plurality of LED chips, and a soldering electrode land and a connector connecting electrode land electrically connected to the chips, on a ceramic substrate. The soldering electrode land is formed of a first conductive material having a function to prevent diffusion to a solder, and the connector connecting electrode land is formed of a second conductive material having a function to prevent oxidation.