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Yang Z.-J.,China Japan Friendship Hospital | Liu J.,Shanxi Province Peoples Hospital | Ge J.-P.,Peoples Hospital of the Xinjiang Uygur Autonomous Region | Chen L.,Shandong University | And 2 more authors.
European Heart Journal | Year: 2012

Aims Cardiovascular disease (CVD) is now the most prevalent and debilitating disease affecting the Chinese population. The goal of the present manuscript was to analyse cardiovascular risk factors and the prevalence of non-fatal CVDs from data gathered from the 20072008 China National Diabetes and Metabolic Disorders Study. Methods and Results A nationally representative sample of 46 239 adults, 20 years of age or older, was randomly recruited using a multistage stratified design method. Lifestyle factors, diagnosis of CVD, stroke, diabetes, and family history of each subject were collected, and an oral glucose tolerance test or a standard meal test was performed. Various non-fatal CVDs were reported by the subjects. SUDAAN software was used to perform all weighted statistical analyses, with P < 0.05 considered statistically significant. The prevalence of coronary heart disease, stroke, and CVDs was 0.74, 1.07, and 1.78 in males; and 0.51, 0.60, and 1.10 in females, respectively. The presence of CVDs increased with age in both males and females. The prevalence of being overweight or obese, hypertension, dyslipidaemia, or hyperglycaemia was 36.67, 30.09, 67.43, and 26.69 in males; and 29.77, 24.79, 63.98, and 23.62 in females, respectively. In the total sample of 46 239 patients, the prevalence of one subject having 1, 2, 3, or <4 of the 5 defined risk factors (i.e. smoking, overweight or obese, hypertension, dyslipidaemia, or hyperglycaemia) was 31.17, 27.38, 17.76, and 10.19, respectively. Following adjustment for gender and age, the odds ratio of CVDs for those who had 1, 2, 3, or <4 risk factors was 2.36, 4.24, 4.88, and 7.22, respectively, when compared with patients with no risk factors. Conclusion Morbidity attributed to the five defined cardiovascular risk factors was high in the Chinese population, with multiple risk factors present in the same individual. Therefore, reasonable prevention strategies should be designed to attenuate the rapid rise in cardiovascular morbidity. © 2011 The Author.

Zhao L.Q.,Shanxi Province Peoples Hospital
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi | Year: 2011

To investigate the prevalence rates of sleep disorders and the correlative in the elderly from Taiyuan city. All of the 3173 elderly (aged 60 years to 100 years) in Taiyuan city were investigated at home through questionnaires, regarding their sleep condition. Subjects with sleep disorders were then screened through questionnaires and reexamined/diagnosed by special doctors. (1) Among the 3173 elderly, 2132 subjects complained of having sleep disorders. The total prevalence of sleep disorders was 67.2%. The prevalence rates of chronic insomnia, multi-dreams, habitual snoring and daytime drowsiness were 39.65%, 38.58%, 26.66% and 34.32% respectively. (2) In the male elderly, the prevalence rates of being awaken early, having more urination at night, daytime drowsiness, sleep-respiratory disturbance and indiscriminate sleep rhythm increased with age (P < 0.01). However, in the female elderly, the prevalence rates of being awaken early, having daytime drowsiness and indiscriminate sleep rhythm also had a tendency of increase (P < 0.01). (3) Living alone, emotional disorder, pain and nocturia (P < 0.01) were the risk factors of chronic insomnia in the male elderly while living alone, numbness/pruritus (P < 0.01), emotional disorder (P < 0.05), were the risk factors of chronic insomnia in the female elderly. The prevalence rates of some sleep disturbances in the elderly in Taiyuan city were generally correspondent with prevalence rates reported elsewhere that called for more attention be paid to the effect of mood disturbance and diseases related to sleep condition among the elderly.

Yan C.,Harbin Medical University | Li Y.,Shanxi Province Peoples Hospital | Yu Z.,Harbin Medical University
Medicine (United States) | Year: 2016

The aim of this study was to estimate the prevalence and patient outcomes of proximal junctional kyphosis (PJK) in pediatric patients and adolescents who received surgical interventions for the treatment of a spinal deformity. Literature was searched in electronic databases, and studies were selected by following précised eligibility criteria. Percent prevalence values of the PJK in individual studies were pooled to achieve a weighted effect size under the random effects model. Subgroup and meta-regression analyses were performed to appraise the factors affecting PJK prevalence. Twenty-six studies (2024 patients) were included in this meta-Analysis. Average age of the patients was 13.8±2.75 years of which 32±20 % were males. Average follow-up was 51.6±38.8 (range 17±13 to 218±60) months. Overall, the percent prevalence of PJK (95% confidence interval) was 11.02 (10.5, 11.5) %; P<0.00001 which was inversely associated with age (meta-regression coefficient:-1.607 [-2.86,-0.36]; 0.014). Revision surgery rate in the patients with PJK was 10%. The prevalence of PJK was positively associated with the proximal junctional angle at last follow-up (coefficient: 2.248; P=0.012) and the change in the proximal junctional angle from surgery to last follow-up (coefficient: 2.139; P=0.014) but not with preoperative proximal junctional angle. The prevalence of PJK in the children and adolescent patients is 11%. About 10% of those affected require revision surgery. © 2016 Wolters Kluwer Health, Inc. All rights reserved.

Xiao J.,China Japan Friendship Hospital | Weng J.,Sun Yat Sen University | Ji L.,Peking University | Jia W.,Shanghai JiaoTong University | And 7 more authors.
Journals of Gerontology - Series A Biological Sciences and Medical Sciences | Year: 2014

Background.Whether insulin secretion and insulin sensitivity in older Chinese differ from younger persons without diabetes has not been examined and is unknown to us.Methods.Oral glucose tolerance test was performed in a total of 32,245 Chinese without diabetes history. Insulin sensitivity was estimated by Matsuda's insulin sensitivity index (Matsuda ISI), and insulin secretion was measured by the insulinogenic index. The insulin secretion and sensitivity were compared among three age groups: 20-39 (the young), 40-59 (the middle), and greater than or equal to 60 years (the older).Results.A higher proportion of postchallenge hyperglycemia (PH), both in prediabetes and in diabetes stage, was associated with older age. In the young, middle, and older age groups, the insulinogenic index median was 10.64, 8.40, and 6.67, respectively, in individuals with normal glucose tolerance (NGT); it was 8.56, 6.12, and 4.98 in individuals with prediabetes, respectively (p <. 001 vs the young group). In these three age groups, the Matsuda insulin sensitivity index was 8.20, 8.39, and 8.84 in individuals with normal glucose tolerance, and it was 5.23, 5.94, and 6.33 in individuals with prediabetes, respectively (p <. 05 vs the young group). These differences were independent of body mass index and waist circumference.Conclusions.Older Chinese without diabetes are characterized with worse insulin secretion and better insulin sensitivity. Insulin insufficiency and insulin resistance may contribute disproportionately to abnormal glucose tolerance in people of different age. © The Author 2013.

Yang W.,China Japan Friendship Hospital | Lu J.,Chinese Peoples Liberation Army | Weng J.,Sun Yat Sen University | Jia W.,Shanghai JiaoTong University | And 16 more authors.
New England Journal of Medicine | Year: 2010

BACKGROUND: Because of the rapid change in lifestyle in China, there is concern that diabetes may become epidemic. We conducted a national study from June 2007 through May 2008 to estimate the prevalence of diabetes among Chinese adults. METHODS: A nationally representative sample of 46,239 adults, 20 years of age or older, from 14 provinces and municipalities participated in the study. After an overnight fast, participants underwent an oral glucose-tolerance test, and fasting and 2-hour glucose levels were measured to identify undiagnosed diabetes and prediabetes (i.e., impaired fasting glucose or impaired glucose tolerance). Previously diagnosed diabetes was determined on the basis of self-report. RESULTS: The age-standardized prevalences of total diabetes (which included both previously diagnosed diabetes and previously undiagnosed diabetes) and prediabetes were 9.7% (10.6% among men and 8.8% among women) and 15.5% (16.1% among men and 14.9% among women), respectively, accounting for 92.4 million adults with diabetes (50.2 million men and 42.2 million women) and 148.2 million adults with prediabetes (76.1 million men and 72.1 million women). The prevalence of diabetes increased with increasing age (3.2%, 11.5%, and 20.4% among persons who were 20 to 39, 40 to 59, and ≥60 years of age, respectively) and with increasing weight (4.5%, 7.6%, 12.8%, and 18.5% among persons with a body-mass index [the weight in kilograms divided by the square of the height in meters] of <18.5, 18.5 to 24.9, 25.0 to 29.9, and ≥30.0, respectively). The prevalence of diabetes was higher among urban residents than among rural residents (11.4% vs. 8.2%). The prevalence of isolated impaired glucose tolerance was higher than that of isolated impaired fasting glucose (11.0% vs. 3.2% among men and 10.9% vs. 2.2% among women). CONCLUSIONS: These results indicate that diabetes has become a major public health problem in China and that strategies aimed at the prevention and treatment of diabetes are needed. Copyright © 2010 Massachusetts Medical Society. All rights reserved.

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