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Jiang E.,Tianjin Hematonosis Hospital | Pan J.,Shanghai Tissuebank Biotechnology Co. | Han M.,Tianjin Hematonosis Hospital | Chen L.,Tianjin Hematonosis Hospital | And 7 more authors.
International Journal of Legal Medicine | Year: 2016

Alleles at the D7S820 STR locus have 6–14 different numbers of a four-nucleotide (GATA) repeat motif arranged in tandem. The D7S820 tri-allelic pattern is rare and has not been reported in the Chinese population. In this study we report a three-banded pattern at the D7S820 locus observed in a Chinese family, in which four family members in two generations had tri-allelic D7S820 genotype 10-11-12 and one family member had an abnormal bi-allele genotype 10–11. All of the four tri-allelic cases had the genotype 10-11-12, probably due to three copies of the D7S820 STR sequence in all cells (Type 2 tri-allelic pattern), and deduced alleles 10–11 were a linked inheritance in this family. © 2015, Springer-Verlag Berlin Heidelberg.

Pan J.,Shanghai Tissuebank Biotechnology Co. | Chen L.N.,Shanghai Tissuebank Biotechnology Co. | Zhuo X.F.,Shanghai Tissuebank Biotechnology Co. | Huang L.P.,Shanghai Tissuebank Biotechnology Co. | Zheng Z.Z.,Shanghai Tissuebank Biotechnology Co.
Tissue Antigens | Year: 2015

Six novel human leukocyte antigen (HLA) alleles were identified using a sequence-based typing of HLA in Chinese individuals. © 2015 John Wiley & Sons A/S.

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