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Ren L.,Shanghai Jingan Geriatric Hospital | Xu H.-Q.,Shanghai Jingan Geriatric Hospital | Du J.-B.,Shanghai Jingan Geriatric Hospital | Weng Q.-L.,Shanghai Jingan Geriatric Hospital | And 4 more authors.
Journal of Shanghai Jiaotong University (Medical Science) | Year: 2013

Objective: To evaluate the influencing factors of compliance with treatment with noninvasive ventilator. Methods: A total of 138 patients treated with noninvasive ventilator were investigated, among whom 48 experienced respiratory failure and 130 had obstructive sleep apnea-hypopnea syndrome (including 40 patients complicated with respiratory failure). The related data of patients were collected, and the potential influencing factors of compliance with treatment with noninvasive ventilator were evaluated, including sex, age, educational background, smoking, body mass index, nasal factors, basic diseases, cognition, type of positive airway pressure, mask type, output pressure of noninvasive ventilator, adverse reactions, psychological status, education pattern, living conditions, economic status, and duration from diagnosis to treatment. The above factors were analysed with Cox regression analysis. Results: Age <65 years (HR=2.513, 95%CI: 1.222-5.167), higher education level (HR=2.740, 95%CI: 1.765-4.255), type I respiratory failure (HR=2.776, 95%CI: 1.547-4.982), type II respiratory failure (HR=2.545, 95%CI: 1.262-5.133), hypertension (HR=2.404, 95%CI: 1.550-3.729), cognition (HR=1.641, 95%CI: 1.114-2.416), patient-family education (HR=3.105, 95%CI: 1.687-5.715), high level economic status (HR=1.871, 95%CI: 1.048-3.343) and bi-level positive airway pressure (BiPAP)(HR=2.329, 95%CI: 1.065-5.094) were factors for improvement of compliance with treatment with noninvasive ventilator (P<0.05 or P<0.01). Conclusion: Education should be conducted on patients with age ≥65 years, lower education level, recognition disorder and continuous positive airway pressure in ventilation, and patient-family education should be carried out to improve the compliance with treatment with noninvasive ventilator.


Zhang H.-Y.,Shanghai JiaoTong University | Qing Y.-Y.,Shanghai JiaoTong University | Zhang Y.-Q.,Shanghai JiaoTong University | Wang K.,Shanghai Jingan Geriatric Hospital | And 3 more authors.
Journal of Shanghai Jiaotong University (Medical Science) | Year: 2014

Objective: To observe the effects of Tai-ji exercise motor imagery on the walk function of patients with hemiplegia after stroke.Methods: A total of 40 hospitalized patients with hemiplegia after stroke who met the inclusion criteria were selected and divided into the group A (n=20) and group B (n=20) by the cross control design method. The experiment was divided into phase I (week 1 to 3), phase II (week 4 to 5), and phase III (week 6 to 8). For group A, patients were treated with routine rehabilitation training combined with Tai-Ji exercise motor imagery therapy at the phase I and routine training at the phase III. For group B, patients were treated with routine rehabilitation training at the phase I and routine training combined with Tai-Ji exercise motor imagery therapy at the phase III. Phase II was the washout period and patients of two groups were not treated with routine rehabilitation training or motor imagery therapy during phase II. The walk function of patients was evaluated by the lower extremity part of Fugl-Meyer motor assessment (FMA), functional ambulation category (FAC), and Tinetti Gait Assessment (TGA) before the experiment and 3, 5, and 8 weeks after the intervention.Results: Scores of three items of the group A and B increased significantly after the intervention. The differences of scores of 3, 5, and 8 weeks after the intervention were statistically significant (P<0.05). The differences of scores of three items of the group A and B before the intervention were not statistically significant (P>0.05). Scores of three items of the group A 3 weeks after the intervention were higher than those of the group B and the differences were statistically significant (P<0.05 or P<0.01). The differences of scores 5 weeks between the two groups after the intervention were not statistically significant (P>0.05). Scores of three items of the group B 8 weeks after the intervention were higher than those of the group A and the differences were statistically significant (P<0.05 or P<0.01).Conclusion: With the increase of intervention time, Tai-ji exercise motor imagery therapy is more helpful for the recovery of walk function of patients with hemiplegia after stroke on the basis of routine rehabilitation training and improves the effect of rehabilitation training.


Ren L.,Shanghai JiaoTong University | Ren L.,Shanghai Jingan Geriatric Hospital | Li Q.-Y.,Shanghai JiaoTong University | Du J.-B.,Shanghai Jingan Geriatric Hospital | And 3 more authors.
Journal of Shanghai Jiaotong University (Medical Science) | Year: 2011

Objective To investigate the strategies of pulmonary rehabilitation for patients with chronic obstructive pulmonary disease (COPD) of different severity. Methods Eighty-nine patients with COPD in stable stage were divided into moderate COPD group (re = 32), severe COPD group (re = 36) and very severe COPD group (re = 21). Each group of patients were randomly subdivided into pulmonary rehahilitation strategy group 1, pulmonary rehabilitation strategy group 2 and control group, and were intervened for 20 weeks. BODE index, 6 minute walking distance (6MWD), Modified Medical Research Council Scale (MMRC), pulmonary function(FEV 1), body mass index (BMI) and acute exacerbation frequency of COPD were compared before and after intervention and among groups. Results After pulmonary rehabilitation intervention for 20 weeks, 6MWD in patients with moderate and severe COPD treated with strategy 2 significantly improved (P < 0. 01), while BODE index, MMRC, BMI and FEV 1 after intervention were not significantly different from those before intervention (P > 0. 05). MMRC of patients with very severe COPD treated with strategy 1 significantly improved after intervention (P < 0.05), while BODE index, 6MWD, BMI and FEV 1 after intervention were not significantly different from those before intervention (P >0. 05). BODE index and 6MWD of severe COPD group treated with strategy 2 improved significantly (P < 0. 000 1), and MMRC of very severe COPD group treated with strategy 1 improved significantly (P < 0. 01). Poisson regression analysis revealed that acute exacerbation frequency of severe COPD patients significantly reduced by pulmonary rehabilitation (P <0.01), while there was no significant change in the other groups (P >0. 05). Conclusion Patients with different severity of COPD may take different pulmonary rehabilitation strategies to achieve the optimal effect.


Liu W.Y.,Shanghai University of Sport | He W.,Shanghai jingAn Geriatric Hospital | Li H.,Neijiang Normal University
Oxidative Medicine and Cellular Longevity | Year: 2013

This work investigates the effects of oxidative stress due to exhaustive training on uncoupling protein 2 (UCP2) and Bcl-2/Bax in rat skeletal muscles. A total of 18 Sprague-Dawley female rats were randomly divided into three groups: the control group (CON), the trained control group (TC), and the exhaustive trained group (ET). Malondialdehyde (MDA), superoxide dismutase (SOD), xanthine oxidase (XOD), ATPase, UCP2, and Bcl-2/Bax ratio in red gastrocnemius muscles were measured. Exhaustive training induced ROS increase in red gastrocnemius muscles, which led to a decrease in the cell antiapoptotic ability (Bcl-2/Bax ratio). An increase in UCP2 expression can reduce ROS production and affect mitochondrial energy production. Thus, oxidative stress plays a significant role in overtraining. © 2013 W. Y. Liu et al.


Sun M.,Shanghai Jingan Geriatric Hospital | Ling X.-M.,Shanghai Jingan Geriatric Hospital | Yu D.-F.,Shanghai Jingan Geriatric Hospital
Journal of Shanghai Jiaotong University (Medical Science) | Year: 2011

Objective To investigate the effects of personalized health education on quality of life in patients with stroke. Methods Seventy patients with stroke were randomly divided into control group and treatment group. Patients in control group were given rehabilitation training and routine health education, while specific and systematic health education on the basis of rehabilitation training were conducted in treatment group. Hamilton anxiety scale (HAMA) was employed to assess the anxiety status, Banthel index scale was adopted to evaluate the daily living, and life satisfaction index was used to assess the life satisfaction of patients. The anxiety status, daily living and life satisfaction were compared between groups before and after treatment. Results There was no significant difference in the scores of HAMA, Banthel index and life satisfaction index between groups before treatment (P>0.05). The scores of HAMA after treatment were significantly lower than those before treatment in two groups (P<0.05), and the scores of Banthel index and life satisfaction index after treatment were significantly higher than those before treatment in two groups (P<0.05). After treatment, the score of HAMA in treatment group was significantly lower than that in control group (P<0.05), and the scores of Banthel index and life satisfaction index in treatment group were significantly higher than those in control group (P<0.05). Conclusion On the basis of rehabilitation training, specifically and systematically personalized health education may improve the quality of life in patients with stroke.

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