Shanghai Jiading Nanxiang Hospital
Shanghai Jiading Nanxiang Hospital
Liu X.-K.,Shanghai Jiading Nanxiang Hospital |
Zhao X.-H.,Shanghai Tongji Hospital |
Yang H.-B.,Shanghai Jiading Nanxiang Hospital |
Lyu J.-L.,Shanghai Jiading Nanxiang Hospital |
Fu Z.-G.,Shanghai Jiading Nanxiang Hospital
Chinese Journal of Medical Imaging Technology | Year: 2015
Objective: To explore the imaging manifestations of congenital abnormalities of inferior vena cava (IVC) and clinical significance with MSCT. Methods: Abdominal contrast enhanced MSCT data of 48 congenital abnormalities of IVC in 960 patients were retrospectively reviewed. The anatomies of IVC on MSCT arterial and venous phase were observed. Post-processing reconstruction methods including MPR and VR were used for analysis. Results: The incidence of congenital abnormalities of IVC was 5.00% (48/960); 4 cases (4/48, 8.33%) were left IVC, showing IVC left to aorta inferior to the renal hilum; 5 cases (5/48, 10.42%) were double IVC, showing two IVC besides the aorta inferior to the renal hilum; 12 cases (12/48, 25.00%) were retroaortic left renal vein, showing left renal vein crossing posterior to the aorta; 26 cases (26/48, 54.17%) were circumaortic left renal vein, showing two left renal veins around the aorta; 1 case (1/48, 2.08%) was azygos continuation of IVC, contrast-enhanced CT scan demonstrated dilatation azygos continuation of IVC and hepatic vein draining directly into right atrium. Conclusion: MSCT can clearly demonstrate the congenital abnormalities of IVC, which has important clinical value in the diagnosis of some IVC related diseases and preventing vascular injury during surgery. Copyright © 2015 by the Press of Chinese Journal of Medical Imaging and Technology.
Xue Z.,Shanghai Jiading Nanxiang Hospital |
Meng Y.,Shanghai Jiading Nanxiang Hospital |
Ge J.,University of Sichuan
Experimental and Therapeutic Medicine | Year: 2017
The effect and related mechanisms of miR-127-5p on the cartilage differentiation of rat bone marrow mesenchymal stem cells (BMSCs) was investigated. Rat BMSCs were generated and transfected with miR-127-5p, RT-PCR and Safranin O staining were used to detect the effect of miR-127-5p on the cartilage differentiation of rat BMSCs. Western blot analysis was used to detect the related mechanisms of miR-127-5p on the cartilage differentiation of rat BMSCs. Genes related to cartilage differentiation such as Sox9, collagen Ⅱ and aggrecan were significantly increased in the group which were transfected with miR-127-5p, while collagen X, which was related to cartilage hypertrophy, was decreased in the miR-127-5p transfected group. Safranin O staining revealed that the expression of chondroitin sulfate was significantly increased in the group of miR-127-5p, than the miRNA control group. Western blot analysis showed that miR-127-5p transfection promoted the expression of Sox9, while decreased the expression of Runx2 of rat BMSCs. In conclusion, via increasing the expression of Sox9 and decreasing the expression of Runx2, miR-127-5p could promote cartilage differentiation and decrease cartilage hypertrophy of rat BMSCs. © 2017, Spandidos Publications. All rights reserved.
Tang F.,Shanghai Jiading Nanxiang Hospital |
Wang Q.-Y.,Shanghai Jiading Nanxiang Hospital |
Xu Z.-L.,Shanghai Jiading Nanxiang Hospital |
Luo Y.-P.,Shanghai Jiading Nanxiang Hospital |
And 2 more authors.
Chinese Journal of Tissue Engineering Research | Year: 2013
Background: The traditional surgical method have large trauma in the treatment of tibiofibular syndesmosis injury, and cannot well complete the repair of ligament. But the suture anchor has clear effect for ligament repair, ligament reconstruction and bone connection. Objective: To investigate the biomechanical properties of the suture anchor in the treatment of tibiofibular syndesmotic injury, and to compare with lag screw internal fixation. Methods: Eight ankle joint specimens were collected, and the biomechanical experiment was performed for stress analysis. The suture anchor technology and lag screw internal fixation were used respectively to treat the tibiofibular syndesmotic injury. The biomechanical properties of the stress strength, stiffness and stability were compared. Results and conclusion: The biomechanical properties of the stress strength, stiffness and stability of suture anchor technology for the treatment of tibiofibular syndesmotic injury were better than those of lag screw internal fixation, and there were significant differences in the strength and stiffness between two methods (P < 0.05); the stress shielding rate of suture anchor technology was lower than that of lag screw internal fixation, and the difference was significant (P < 0.05); the tibiofibular syndesmosis separated displacement of suture anchor technology was lower than that of lag screw internal fixation, and the difference was significant (P < 0.05). The results indicate that the suture anchor technology is a minimal invasion and good method to realize physiological reconstruction and elastic fixation with stable fixation strength and less trauma, and without secondary operation.
Hu Y.,Shanghai Jiading Nanxiang Hospital |
Yu A.,Shanghai Jiading Nanxiang Hospital |
Chen X.,Shanghai Jiading Nanxiang Hospital |
Wang G.,Shanghai Jiading Nanxiang Hospital |
Feng X.,Shanghai JiaoTong University
BioMed Research International | Year: 2015
Candida africana, an emerging yeast pathogen, is closely related to Candida albicans and most commonly involved in vulvovaginal candidiasis (VVC). However, its prevalence in candidal balanoposthitis is still unclear. In this study, the prevalence of C. africana in both candidal balanoposthitis and VVC in a sexually transmitted diseases (STD) clinic in Shanghai, China, was analyzed, and the molecular characterization and susceptible profiles of C. africana isolates were investigated. As results, C. africana was only isolated in 5 out of 79 (6.3%) cases of candidal balanoposthitis rather than cases with vulvovaginal candidiasis. Among them, 4 out of 5 isolates share the same genotype of DST 782 with an isolate from vaginal swab in Japan published previously. All C. africana isolates were susceptible to amphotericin B, flucytosine, fluconazole, itraconazole, voriconazole, posaconazole, caspofungin, and micafungin. © 2015 Yang Hu et al.